Efficient gene delivery via non-covalent complexes of folic acid and polyethylenimine

Journal of Controlled Release

Volumn 77, Issue 1-2, 2001, Pages 131-138

  Guo, Wenjin ^a   Lee, Robert J ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Folic acid; Polyethylenimine; Polyplex; Transfection

Indexed keywords

CHOLIC ACID; CITRIC ACID; EDETIC ACID; FOLIC ACID; GLUTAMIC ACID; LUCIFERASE; PLASMID DNA; POLYETHYLENEIMINE;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DRUG COMPLEX; DNA TRANSFECTION; DRUG ACTIVITY; DRUG COST; DRUG FORMULATION; GENE TARGETING; GENE THERAPY; GLIOMA CELL; HUMAN; HUMAN CELL; MOUTH CARCINOMA; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PRODUCTIVITY; PROTEIN EXPRESSION; RELIABILITY; SARCOMA CELL; SERUM;

DNA; FOLIC ACID; GENE THERAPY; GENE TRANSFER, HORIZONTAL; HUMANS; KB CELLS; PARTICLE SIZE; POLYETHYLENEIMINE; TRANSFECTION;

EID: 0035834270     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00456-4     Document Type: Article

References (18)

1. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
2. Adenovirus enhancement of polyethylenimine-mediated transfer of regulated genes in differentiated cells
3. Polyethylenimine-mediated transfection of human monocytes with the IFN-g gene: An approach for cancer adoptive immunotherapy
4. Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs
5. ExGen 500 is an efficient vector for gene delivery to lung epithelial cells in vitro and in vivo
6. Rapid crossing of the pulmonary endothelial barrier by polyethylenimine/DNA complexes
7. Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system
8. Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells
9. Efficient gene delivery into human dendritic cells by adenovirus polyethylenimine and mannose polyethylenimine transfection
10. Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway
11. Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery
12. Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody
13. Receptor-targeted gene delivery via folate-conjugated polyethylenimine
14. In vitro gene delivery to hepatocytes with galactosylated polyethylenimine
15. Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold
16. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
17. Lipoplex size is a major determinant of in vitro lipofection efficiency
18. Folate-mediated targeting of therapeutic and imaging agents to cancers