Synthesis and evaluation of a novel ligand for folate-mediated targeting liposomes

International Journal of Pharmaceutics

Volumn 356, Issue 1-2, 2008, Pages 29-36

  Xiang, Guangya ^a,b   Wu, Jun ^b   Lu, Yanhui ^b   Liu, Zhilan ^b,c   Lee, Robert J ^b,d  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b OHIO STATE UNIVERSITY   (United States)

^c WUHAN UNIVERSITY   (China)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

Cancer; Doxorubicin; Folate receptor; Liposomes; Nanotechnology; Targeted drug delivery

Indexed keywords

DOXORUBICIN; FOLATE POLYETHYLENE GLYCOL CHOLESTEROL; FOLATE POLYETHYLENE GLYCOL CHOLESTEROL HEMISUCCINATE; FOLATE RECEPTOR; FOLATE RECEPTOR ALPHA; FOLIC ACID; FOLIC ACID DERIVATIVE; LIPOSOME; POLYCARBONATE;

ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN KB; CONTROLLED STUDY; CYTOTOXICITY; DRUG CLEARANCE; DRUG MECHANISM; DRUG METABOLISM; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PLASMA CLEARANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CARRIER PROTEINS; CHOLESTEROL; CHOLESTEROL ESTERS; DOXORUBICIN; DRUG DELIVERY SYSTEMS; FEMALE; FOLIC ACID; HALF-LIFE; HUMANS; INHIBITORY CONCENTRATION 50; KB CELLS; LIGANDS; LIPOSOMES; MICE; MICE, INBRED ICR; PARTICLE SIZE; POLYETHYLENE GLYCOLS; RECEPTORS, CELL SURFACE;

EID: 42649130036     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.12.030     Document Type: Article

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