Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction

American Journal of Pathology

Volumn 178, Issue 2, 2011, Pages 572-579

  Kato, Noritoshi ^a   Kosugi, Tomoki ^a   Sato, Waichi ^a   Ishimoto, Takuji ^a   Kojima, Hiroshi ^a   Sato, Yuka ^a   Sakamoto, Kazuma ^a   Maruyama, Shoichi ^a   Yuzawa, Yukio ^a   Matsuo, Seiichi ^a   Kadomatsu, Kenji ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD147 ANTIGEN; GELATINASE A; GELATINASE B; HYALURONIC ACID; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DISEASE SEVERITY; FIBROBLAST; GENE SILENCING; IN VIVO STUDY; KIDNEY FIBROSIS; MACROPHAGE; MOUSE; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; URETER OBSTRUCTION;

EID: 79951823677     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2010.10.009     Document Type: Article

References (56)

1. Schainuck LI, Striker GE, Cutler RE, Benditt EP: Structural-functional correlations in renal disease. II. The correlations. Hum Pathol 1970, 1:631-641
2. Gabbiani G: The myofibroblast in wound healing and fibrocontractive diseases. J Pathol 2003, 200:500-503
3. Mauviel A, Chung KY, Agarwal A, Tamai K, Uitto J: Cell-specific induction of distinct oncogenes of the Jun family is responsible for differential regulation of collagenase gene expression by transforming growth factor-beta in fibroblasts and keratinocytes. J Biol Chem 1996, 271:10917-10923
4. Philipp K, Riedel F, Germann G, Hormann K, Sauerbier M: TGF-beta antisense oligonucleotides reduce mRNA expression of matrix metalloproteinases in cultured wound-healing-related cells. Int J Mol Med 2005, 15:299-303
5. Karsdal MA, Larsen L, Engsig MT, Lou H, Ferreras M, Lochter A, Delaisse JM, Foged NT: Matrix metalloproteinase-dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosis. J Biol Chem 2002, 277:44061-44067 (Pubitemid 36157833)
6. Yu Q, Stamenkovic I: Cell surface-localized matrix metalloproteinase- 9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev 2000, 14:163-176 (Pubitemid 30070982)
7. Jenkins RH, Thomas GJ, Williams JD, Steadman R: Myofibroblastic differentiation leads to hyaluronan accumulation through reduced hyaluronan turnover. J Biol Chem 2004, 279:41453-41460 (Pubitemid 39313585)
8. Meran S, Thomas D, Stephens P, Martin J, Bowen T, Phillips A, Steadman R: Involvement of hyaluronan in regulation of fibroblast phenotype. J Biol Chem 2007, 282:25687-25697 (Pubitemid 47372811)
9. Meran S, Thomas DW, Stephens P, Enoch S, Martin J, Steadman R, Phillips AO: Hyaluronan facilitates transforming growth factor-beta1-mediated fibroblast proliferation. J Biol Chem 2008, 283:6530-6545
10. Webber J, Jenkins RH, Meran S, Phillips A, Steadman R: Modulation of TGFbeta1-dependent myofibroblast differentiation by hyaluronan. Am J Pathol 2009, 175:148-160
11. Webber J, Meran S, Steadman R, Phillips A: Hyaluronan orchestrates transforming growth factor-beta1-dependent maintenance of myofibroblast phenotype. J Biol Chem 2009, 284:9083-9092
12. Biswas C: Tumor cell stimulation of collagenase production by fibroblasts. Biochem Biophys Res Commun 1982, 109:1026-1034
13. Yurchenko V, Constant S, Bukrinsky M: Dealing with the family: cD147 interactions with cyclophilins. Immunology 2006, 117:301-309
14. Biswas C, Zhang Y, DeCastro R, Guo H, Nakamura T, Kataoka H, Nabeshima K: The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res 1995, 55:434-439
15. Riethdorf S, Reimers N, Assmann V, Kornfeld JW, Terracciano L, Sauter G, Pantel K: High incidence of EMMPRIN expression in human tumors. Int J Cancer 2006, 119:1800-1810 (Pubitemid 44356836)
16. Schneiderhan W, Scheler M, Holzmann KH, Marx M, Gschwend JE, Bucholz M, Gress TM, Seufferlein T, Adler G, Oswald F: CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models. Gut 2009, 58:1391-1398
17. Slomiany MG, Grass GD, Robertson AD, Yang XY, Maria BL, Beeson C, Toole BP: Hyaluronan. CD44, and EMMPRIN regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cells. Cancer Res 2009, 69:1293-1301
18. Chen X, Lin J, Kanekura T, Su J, Lin W, Xie H, Wu Y, Li J, Chen M, Chang J: A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma. Cancer Res 2006, 66:11323-11330 (Pubitemid 46009963)
19. Su J, Chen X, Kanekura T: A CD147-targeting siRNA inhibits the proliferation, invasiveness, and VEGF production of human malignant melanoma cells by down-regulating glycolysis. Cancer Lett 2009, 273:140-147
20. Tang Y, Kesavan P, Nakada MT, Yan L: Tumor-stroma interaction: positive feedback regulation of extracellular matrix metalloproteinase inducer (EMMPRIN) expression and matrix metalloproteinase-dependent generation of soluble EMMPRIN. Mol Cancer Res 2004, 2:73-80 (Pubitemid 38250423)
21. Tang Y, Nakada MT, Kesavan P, McCabe F, Millar H, Rafferty P, Bugelski P, Yan L: Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases. Cancer Res 2005, 65: 3193-3199 (Pubitemid 40524601)
22. Tang Y, Nakada MT, Rafferty P, Laraio J, McCabe FL, Millar H, Cunningham M, Snyder LA, Bugelski P, Yan L: Regulation of vascular endothelial growth factor expression by EMMPRIN via the PI3K-Akt signaling pathway. Mol Cancer Res 2006, 4:371-377 (Pubitemid 44035156)
23. Misra S, Ghatak S, Zoltan-Jones A, Toole BP: Regulation of multidrug resistance in cancer cells by hyaluronan. J Biol Chem 2003, 278: 25285-25288 (Pubitemid 36835275)
24. Marieb EA, Zoltan-Jones A, Li R, Misra S, Ghatak S, Cao J, Zucker S, Toole BP: Emmprin promotes anchorage-independent growth in human mammary carcinoma cells by stimulating hyaluronan production. Cancer Res 2004, 64:1229-1232 (Pubitemid 38235586)
25. Toole BP: Hyaluronan: from extracellular glue to pericellular cue. Nat Rev Cancer 2004, 4:528-539
26. Tang W, Chang SB, Hemler ME: Links between CD147 function, glycosylation, and caveolin-1. Mol Biol Cell 2004, 15:4043-4050 (Pubitemid 39122010)
27. Arora K, Gwinn WM, Bower MA, Watson A, Okwumabua I, MacDonald HR, Bukrinsky MI, Constant SL: Extracellular cyclophilins contribute to the regulation of inflammatory responses. J Immunol 2005, 175:517-522 (Pubitemid 40884357)
28. Kirk P, Wilson MC, Heddle C, Brown MH, Barclay AN, Halestrap AP: CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. EMBO J 2000, 19:3896-3904 (Pubitemid 30608530)
29. Philp NJ, Wang D, Yoon H, Hjelmeland LM: Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells. Invest Ophthalmol Vis Sci 2003, 44:1716-1721 (Pubitemid 36378602)
30. Huet E, Vallee B, Szul D, Verrecchia F, Mourah S, Jester JV, Hoang-Xuan T, Menashi S, Gabison EE: Extracellular matrix metalloproteinase inducer/CD147 promotes myofibroblast differentiation by inducing alpha-smooth muscle actin expression and collagen gel contraction: implications in tissue remodeling. FASEB J 2008, 22: 1144-1154 (Pubitemid 351519969)
31. Igakura T, Kadomatsu K, Kaname T, Muramatsu H, Fan QW, Miyauchi T, Toyama Y, Kuno N, Yuasa S, Takahashi M, Senda T, Taguchi O, Yamamura K, Arimura K, Muramatsu T: A null mutation in basigin, an immunoglobulin superfamily member, indicates its important roles in peri-implantation development and spermatogenesis. Dev Biol 1998, 194:152-165 (Pubitemid 28117579)
32. Igakura T, Kadomatsu K, Taguchi O, Muramatsu H, Kaname T, Miyauchi T, Yamamura K, Arimura K, Muramatsu T: Roles of basigin, a member of the immunoglobulin superfamily, in behavior as to an irritating odor, lymphocyte response, and blood-brain barrier. Biochem Biophys Res Commun 1996, 224:33-36 (Pubitemid 26252407)
33. Naruhashi K, Kadomatsu K, Igakura T, Fan QW, Kuno N, Muramatsu H, Miyauchi T, Hasegawa T, Itoh A, Muramatsu T, Nabeshima T: Abnormalities of sensory and memory functions in mice lacking Bsg gene. Biochem Biophys Res Commun 1997, 236:733-737 (Pubitemid 27384700)
34. Kato N, Yuzawa Y, Kosugi T, Hobo A, Sato W, Miwa Y, Sakamoto K, Matsuo S, Kadomatsu K: The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion. J Am Soc Nephrol 2009, 20:1565-1576
35. Chen S, Kadomatsu K, Kondo M, Toyama Y, Toshimori K, Ueno S, Miyake Y, Muramatsu T: Effects of flanking genes on the phenotypes of mice deficient in basigin/CD147. Biochem Biophys Res Commun 2004, 324:147-153 (Pubitemid 39311472)
36. Nomura A, Nishikawa K, Yuzawa Y, Okada H, Morgan BP, Piddlesden SJ, Nadai M, Hasegawa T, Matsuo S: Tubulointestinal injury induced in rats by a monoclonal antibody that inhibits function of membrane inhibitor of complement. J Clin Invest 1995, 96:2348-2356
37. Kadomatsu K, Hagihara M, Akhter S, Fan QW, Muramatsu H, Muramatsu T: Midkine induces the transformation of NIH3T3 cells. Br J Cancer 1997, 75:354-359 (Pubitemid 27051049)
38. Kosugi T, Yuzawa Y, Sato W, Arata-Kawai H, Suzuki N, Kato N, Matsuo S, Kadomatsu K: Midkine is involved in tubulointerstitial inflammation associated with diabetic nephropathy. Lab Invest 2007, 87:903-913 (Pubitemid 47267810)
39. Camussi G, Brentijens JR, Noble B, Kerjaschiki D, Malavasi F, Roholt OA, Farquhar MG, Andres G: Antibody-induced redistribution of Hymann antigen on the surface of cultured glomerular visceral epithelial cells: possible role in the pathogenesis of Hymann glomerulonephritis. J Immunol 1985, 135:2409-2416 (Pubitemid 16217128)
40. Tsuboi N, Yoshikai Y, Matsuo S, Kikuchi T, Iwami K, Nagai Y, Takeuchi O, Akira S, Matsuguchi T: Roles of toll-like receptors in C-C chemokine production by renal epithelial cells. J Immunol 2002, 169:2026-2033 (Pubitemid 34857667)
41. Nguyen A, Burack WR, Stock JL, Kortum R, Chaika OV, Afkarian M, Muller WJ, Murphy KM, Morrison DK, Lewis RE, McNeish J, Shaw AS: Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol Cell Biol 2002, 22:3035-3045 (Pubitemid 34437462)
42. Chevalier RL, Forbes MS, Thornhill BA: Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy. Kidney Int 2009, 75:1145-1152
43. Bascands JL, Schanstra JP: Obstructive nephropathy: insights from genetically engineered animals. Kidney Int 2005, 68:925-937
44. Rouschop KM, Sewnath ME, Claessen N, Roelofs JJ, Hoedemaeker I, van der Neut R, Aten J, Pals ST, Weening JJ, Florquin S: CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy. J Am Soc Nephrol 2004, 15:674-686 (Pubitemid 38294797)
45. Wolf G: Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway. Kidney Int 2006, 70:1914-1919
46. Steinmann-Niggli K, Ziswiler R, Kung M, Marti HP: Inhibition of matrix metalloproteinases attenuates anti-Thy1.1 nephritis. J Am Soc Nephrol 1998, 9:397-407
47. Marti HP, McNeil L, Thomas G, Davies M, Lovett DH: Molecular characterization of a low-molecular-mass matrix metalloproteinase secreted by glomerular mesangial cells as PUMP-1. Biochem J 1992, 285(Pt 3):899-905
48. Deora AA, Philp N, Hu J, Bok D, Rodriguez-Boulan E: Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia. Proc Natl Acad Sci U S A 2005, 102:16245-16250 (Pubitemid 41688899)
49. Toole BP, Slomiany MG: Hyaluronan. CD44 and Emmprin: partners in cancer cell chemoresistance. Drug Resist Updat 2008, 11:110-121
50. Klahr S, Morrissey J: Obstructive nephropathy and renal fibrosis. Am J Physiol Renal Physiol 2002, 283:F861-875
51. Lange-Sperandio B, Cachat F, Thornhill BA, Chevalier RL: Selectins mediate macrophage infiltration in obstructive nephropathy in newborn mice. Kidney Int 2002, 61:516-524 (Pubitemid 34102591)
52. Lin SL, Kisseleva T, Brenner DA, Duffield JS: Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am J Pathol 2008, 173:1617-1627
53. Liu Y: New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol 2010, 21:212-222
54. Zavadil J, Bottinger EP: TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 2005, 24:5764-5774
55. Zeisberg M, Maeshima Y, Mosterman B, Kalluri R: Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells. Am J Pathol 2002, 160:2001-2008 (Pubitemid 34663393)
56. Yang J, Liu Y: Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol 2001, 159:1465-1475 (Pubitemid 32947976)