Tumor-Stroma Interaction: Positive Feedback Regulation of Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) Expression and Matrix Metalloproteinase-Dependent Generation of Soluble EMMPRIN

Molecular Cancer Research

Volumn 2, Issue 2, 2004, Pages 73-80

  Tang, Yi ^a   Kesavan, Prabakaran ^a   Nakada, Marian T ^a   Yan, Li ^a  

^a CENTOCOR INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD147 ANTIGEN; GELATINASE B; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; PROTEINASE; RECOMBINANT PROTEIN;

ANGIOGENESIS; ARTICLE; BREAST CANCER; CARBOXY TERMINAL SEQUENCE; CELL INTERACTION; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST; GENE EXPRESSION; GENE INDUCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; METASTASIS; NUCLEOTIDE SEQUENCE; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; REGULATORY MECHANISM; SOLID TUMOR; TUMOR GROWTH;

ANTIGENS, CD; ANTIGENS, CD147; ANTIGENS, NEOPLASM; BREAST NEOPLASMS; CELL LINE, TUMOR; CELLS, CULTURED; COCULTURE TECHNIQUES; FEEDBACK, BIOCHEMICAL; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASES; RECOMBINANT PROTEINS; SOLUBILITY; STROMAL CELLS; TRANSFECTION;

EID: 1342322842     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Nelson AR, Fingleton B, Rothenberg ML, Matrisian LM. Matrix metalloproteinases: biologic activity and clinical implications. J Clin Oncol, 2000;18:1135-49.
2. Fang J, Shing Y, Wiederschain D, Yan L, Butterfield C, Jackson G, et al. Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model. Proc Natl Acad Sci USA, 2000;97:3884-9.
3. Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, et al. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol, 2000;2:737-44.
4. Gilles C, Polette M, Piette J, Birembaut P, Foidart JM. Epithelial-to-mesenchymal transition in HPV-33-transfected cervical keratinocytes is associated with increased invasiveness and expression of gelatinase A. Int J Cancer, 1994;59:661-6.
5. Gilles C, Polette M, Piette J, Munaut C, Thompson EW, Birembaut P, et al. High level of MT-MMP expression is associated with invasiveness of cervical cancer cells. Int J Cancer, 1996;65:209-13.
6. Moses MA, Wiederschain D, Loughlin KR, Zurakowski D, Lamb CC, Freeman MR. Increased incidence of matrix metalloproteinases in urine of cancer patients. Cancer Res, 1998;58:1395-9.
7. Zucker S, Hymowitz M, Conner C, Zarrabi HM, Hurewitz AN, Matrisian L, et al. Measurement of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues. Clinical and experimental applications. Ann NY Acad Sci, 1999;878:212-27.
8. Lokeshwar BL, Selzer MG, Block NL, Gunja-Smith Z. Secretion of matrix metalloproteinases and their inhibitors (tissue inhibitor of metalloproteinases) by human prostate in explant cultures: reduced tissue inhibitor of metalloproteinase secretion by malignant tissues. Cancer Res, 1993;53:4493-8.
9. Powell WC, Knox JD, Navre M, Grogan TM, Kittelson J, Nagle RB, et al. Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice. Cancer Res, 1993;53:417-22.
10. Wood M, Fudge K, Mohler JL, Frost AR, Garcia F, Wang M, et al. In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer. Clin & Exp Metastasis, 1997;15:246-58.
11. Sehgal G, Hua J, Bernhard EJ, Sehgal I, Thompson TC, Muschel RJ. Requirement for matrix metalloproteinase-9 (gelatinase B) expression in metastasis by murine prostate carcinoma. Am J Pathol, 1998;152:591-6.
12. Kuniyasu H, Troncoso P, Johnston D, Bucana CD, Tahara E, Fidler IJ, et al. Relative expression of type IV collagenase, E-cadherin, and vascular endothelial growth factor/vascular permeability factor in prostatectomy specimens distinguishes organ confined from pathologically advanced prostate cancers. Clin Cancer Res, 2000;6:2295-308.
13. Basset P, Wolf C, Chambon P. Expression of the stromelysin-3 gene in fibroblastic cells, of invasive carcinomas of the breast and other human tissues: a review. Breast Cancer Res Treat, 1993;24:185-93.
14. Okada A, Belloeq JP, Rouyer N, Chenard MP, Rio MC, Chambon P, et al. Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc Natl Acad Sci USA, 1995;92:2730-4.
15. Majmudar G, Nelson BR, Jensen TC, Voorhees JJ, Johnson TM. Increased expression of stromelysin-3 in basal cell carcinomas. Mol Carcinog, 1994;9:17-23.
16. Polette M, Gilles C, Marchand V, Lorenzato M, Toole B, Tournier JM, et al. Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers. J Histochem Cytochem, 1997;45:703-709.
17. Guo H, Zucker S, Gordon MK, Toole BP, Biswas C. Stimulation of matrix metalloproteinase production by recombinant extracellular matrix metalloproteinase inducer from transfected Chinese hamster ovary cells. J Biol Chem, 1997;272:24-27.
18. Lim M, Martinez T, Jablons D, Cameron R, Guo H, Toole B, et al. Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38. FEBS Lett, 1998;441:88-92.
19. Biswas C, Zhang Y, DeCastro R, Guo H, Nakamura T, Kataoka H, et al. The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res, 1995;55:434-9.
20. Ellis SM, Nabeshima K, Biswas C. Monoclonal antibody preparation and purification of a tumor cell collagenase-stimulatory factor. Cancer Res, 1989;49:3385-91.
21. Kataoka H, DeCastro R, Zucker S, Biswas C. Tumor cell-derived collagenase-stimulatory factor increases expression of interstitial collagenase, stromelysin, and 72-kDa gelatinase. Cancer Res, 1993;53:3154-8.
22. Sameshima T, Nabeshima K, Toole BP, Yokogami K, Okada Y, Goya T, et al. Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts. Cancer Lett, 2002;157:177-84.
23. Muraoka K, Nabeshima K, Murayama T, Biswas C, Koono M. Enhanced expression of a tumor-cell-derived collagenase-stimulatory factor in urothelial carcinoma: its usefulness as a tumor marker for bladder cancers. Int J Cancer, 1993;55:19-26.
24. Javadpour N, Guirguis R. Tumor collagenase-stimulating factor and tumor autocrine motility factor as tumor markers in bladder cancer - an update. Eur Urol, 1992;21 Suppl 1:1-4.
25. Sameshima T, Nabeshima K, Toole BP, Yokogami K, Okada Y, Goya T, et al. Expression of emmprin (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas. Int J Cancer, 2000;88:21-7.
26. Zucker S, Hymowitz M, Rollo EE, Mann R, Conner CE, Cao J, et al. Tumorigenic potential of extracellular matrix metalloproteinase inducer. Am J Pathol, 2001;158:1921-8.
27. Prescott J, Troccoli N, Biswas C. Coordinate increase in collagenase mRNA and enzyme levels in human fibroblasts treated with the tumor cell factor, TCSF. Biochem Int, 1989;19:257-66.
28. Liotta LA, Kohn EC. The microenvironment of the tumour-host interface. Nature, 2001;411:375-9.
29. Ko K, Yazumi S, Yoshikawa K, Konda Y, Nakajima M, Chiba T, et al. Activation of fibroblast-derived matrix metalloproteinase-2 by colon-cancer cell in non-contact co-cultures. Int J Cancer, 2000;87:165-72.
30. Bordador LC, Li X, Toole B, Chen B, Regezi J, Zardi L, et al. Expression of emmprin by oral squamous cell carcinoma. Int J Cancer, 2000;85:347-52.
31. Taylor PM, Woodfield RJ, Hodgkin MN, Petitt TR, Martin A, Kerr DJ, et al. Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A(2) and 5-lipoxygenase catalyzed pathway. Oncogene, 2002;21:5765-72.
32. Caudroy S, Polette M, Nawrocki-Raby B, Cao J, Toole BP, Zucker S, et al. EMMPRIN-mediated MMP regulation in tumor and endothelial cells. Clin & Exp Metastasis, 2002;19:697-702.
33. Sun J, Hemler ME. Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions. Cancer Res, 2001;61:2276-81.
34. Davidson B, Goldberg I, Berner A, Kristensen GB, Reich R. EMMPRIN (extracellular matrix metalloproteinase inducer) is a novel marker of poor outcome in serous ovarian carcinoma. Clin & Exp Metastasis, 2003;20:161-9.
35. Kanekura T, Chen X, Kanzaki T. Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts. Int J Cancer, 2002;99:520-8.