-
1
-
-
70350718157
-
Cutting edge: Natalizumab blocks adhesion but not initial contact of human T cells to the blood-brain barrier in vivo in an animal model of multiple sclerosis
-
Coisne, C., Mao, W. and Engelhardt, B., Cutting edge: Natalizumab blocks adhesion but not initial contact of human T cells to the blood-brain barrier in vivo in an animal model of multiple sclerosis. J. Immunol. 2009. 182: 5909-5913.
-
(2009)
J. Immunol.
, vol.182
, pp. 5909-5913
-
-
Coisne, C.1
Mao, W.2
Engelhardt, B.3
-
2
-
-
48949117580
-
The blood-central nervous system barriers actively control immune cell entry into the central nervous system
-
Engelhardt, B., The blood-central nervous system barriers actively control immune cell entry into the central nervous system. Curr. Pharm. Des. 2008. 14: 1555-1565.
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 1555-1565
-
-
Engelhardt, B.1
-
3
-
-
0032535368
-
The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin
-
Engelhardt, B., Laschinger, M., Schulz, M., Samulowitz, U., Vestweber, D. and Hoch, G., The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin. J. Clin. Invest. 1998. 102: 2096-2105.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 2096-2105
-
-
Engelhardt, B.1
Laschinger, M.2
Schulz, M.3
Samulowitz, U.4
Vestweber, D.5
Hoch, G.6
-
4
-
-
0032981648
-
Adhesion molecule expression and regulation on cells of the central nervous system
-
Lee, S. J. and Benveniste, E. N., Adhesion molecule expression and regulation on cells of the central nervous system. J. Neuroimmunol. 1999. 98: 77-88.
-
(1999)
J. Neuroimmunol.
, vol.98
, pp. 77-88
-
-
Lee, S.J.1
Benveniste, E.N.2
-
5
-
-
67349218765
-
alpha4 Integrin/FN-CS1 mediated leukocyte adhesion to brain microvascular endothelial cells under flow conditions
-
Man, S., Tucky, B., Bagheri, N., Li, X., Kochar, R. and Ransohoff, R. M., alpha4 Integrin/FN-CS1 mediated leukocyte adhesion to brain microvascular endothelial cells under flow conditions. J. Neuroimmunol. 2009. 210: 92-99.
-
(2009)
J. Neuroimmunol.
, vol.210
, pp. 92-99
-
-
Man, S.1
Tucky, B.2
Bagheri, N.3
Li, X.4
Kochar, R.5
Ransohoff, R.M.6
-
6
-
-
37149030961
-
Natalizumab: targeting alpha4-integrins in multiple sclerosis
-
Engelhardt, B. and Kappos, L., Natalizumab: targeting alpha4-integrins in multiple sclerosis. Neurodegener. Dis. 2008. 5: 16-22.
-
(2008)
Neurodegener. Dis.
, vol.5
, pp. 16-22
-
-
Engelhardt, B.1
Kappos, L.2
-
7
-
-
0026574125
-
Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering
-
Ruegg, C., Postigo, A. A., Sikorski, E. E., Butcher, E. C., Pytela, R. and Erle, D. J., Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering. J. Cell Biol. 1992. 117: 179-189.
-
(1992)
J. Cell Biol.
, vol.117
, pp. 179-189
-
-
Ruegg, C.1
Postigo, A.A.2
Sikorski, E.E.3
Butcher, E.C.4
Pytela, R.5
Erle, D.J.6
-
8
-
-
0025124607
-
Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1
-
Guan, J. L. and Hynes, R. O., Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1. Cell 1990. 60: 53-61.
-
(1990)
Cell
, vol.60
, pp. 53-61
-
-
Guan, J.L.1
Hynes, R.O.2
-
9
-
-
0034629151
-
The alpha(4) integrin subunit Tyr(187) has a key role in alpha(4)beta(7)-dependent cell adhesion
-
Ruiz-Velasco, N., Guerrero-Esteo, M., Briskin, M. J. and Teixido, J., The alpha(4) integrin subunit Tyr(187) has a key role in alpha(4)beta(7)-dependent cell adhesion. J. Biol. Chem. 2000. 275: 7052-7059.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7052-7059
-
-
Ruiz-Velasco, N.1
Guerrero-Esteo, M.2
Briskin, M.J.3
Teixido, J.4
-
10
-
-
0027237424
-
Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1
-
Berlin, C., Berg, E. L., Briskin, M. J., Andrew, D. P., Kilshaw, P. J., Holzmann, B., Weissman, I. L. et al., Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell 1993. 74: 185.
-
(1993)
Cell
, vol.74
, pp. 185
-
-
Berlin, C.1
Berg, E.L.2
Briskin, M.J.3
Andrew, D.P.4
Kilshaw, P.J.5
Holzmann, B.6
Weissman, I.L.7
-
11
-
-
0025906789
-
Expression of vascular addressins and ICAM-1 by endothelial cells in the spinal cord during chronic relapsing experimental allergic encephalomyelitis in the Biozzi AB/H mouse
-
O'Neill, J. K., Butter, C., Baker, D., Gschmeissner, S. E., Kraal, G., Butcher, E. C. and Turk, J. L., Expression of vascular addressins and ICAM-1 by endothelial cells in the spinal cord during chronic relapsing experimental allergic encephalomyelitis in the Biozzi AB/H mouse. Immunology 1991. 72: 520-525.
-
(1991)
Immunology
, vol.72
, pp. 520-525
-
-
O'Neill, J.K.1
Butter, C.2
Baker, D.3
Gschmeissner, S.E.4
Kraal, G.5
Butcher, E.C.6
Turk, J.L.7
-
12
-
-
0028283232
-
Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse
-
Steffen, B. J., Butcher, E. C. and Engelhardt, B., Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse. Am. J. Pathol. 1994. 145: 189-201.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 189-201
-
-
Steffen, B.J.1
Butcher, E.C.2
Engelhardt, B.3
-
13
-
-
0029952623
-
ICAM-1, VCAM-1, and MAdCAM-1 are expressed on choroid plexus epithelium but not endothelium and mediate binding of lymphocytes in vitro
-
Steffen, B. J., Breier, G., Butcher, E. C., Schulz, M. and Engelhardt, B., ICAM-1, VCAM-1, and MAdCAM-1 are expressed on choroid plexus epithelium but not endothelium and mediate binding of lymphocytes in vitro. Am. J. Pathol. 1996. 148: 1819-1838.
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 1819-1838
-
-
Steffen, B.J.1
Breier, G.2
Butcher, E.C.3
Schulz, M.4
Engelhardt, B.5
-
14
-
-
0033622029
-
Beta7 integrins contribute to demyelinating disease of the central nervous system
-
Kanwar, J. R., Harrison, J. E., Wang, D., Leung, E., Mueller, W., Wagner, N. and Krissansen, G. W., Beta7 integrins contribute to demyelinating disease of the central nervous system. J. Neuroimmunol. 2000. 103: 146-152.
-
(2000)
J. Neuroimmunol.
, vol.103
, pp. 146-152
-
-
Kanwar, J.R.1
Harrison, J.E.2
Wang, D.3
Leung, E.4
Mueller, W.5
Wagner, N.6
Krissansen, G.W.7
-
15
-
-
0033667644
-
Prevention of a chronic progressive form of experimental autoimmune encephalomyelitis by an antibody against mucosal addressin cell adhesion molecule-1, given early in the course of disease progression
-
Kanwar, J. R., Kanwar, R. K., Wang, D. and Krissansen, G. W., Prevention of a chronic progressive form of experimental autoimmune encephalomyelitis by an antibody against mucosal addressin cell adhesion molecule-1, given early in the course of disease progression. Immunol. Cell Biol. 2000. 78: 641-645.
-
(2000)
Immunol. Cell Biol.
, vol.78
, pp. 641-645
-
-
Kanwar, J.R.1
Kanwar, R.K.2
Wang, D.3
Krissansen, G.W.4
-
16
-
-
40049098305
-
Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice
-
Deutsch, U., Schlaeger, T. M., Dehouck, B., Doring, A., Tauber, S., Risau, W. and Engelhardt, B., Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice. Exp. Cell Res. 2008. 314: 1202-1216.
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 1202-1216
-
-
Deutsch, U.1
Schlaeger, T.M.2
Dehouck, B.3
Doring, A.4
Tauber, S.5
Risau, W.6
Engelhardt, B.7
-
17
-
-
0028984949
-
alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow
-
Berlin, C., Bargatze, R. F., Campbell, J. J., von Andrian, U. H., Szabo, M. C., Hasslen, S. R., Nelson, R. D. et al., alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell 1995. 80: 413-422.
-
(1995)
Cell
, vol.80
, pp. 413-422
-
-
Berlin, C.1
Bargatze, R.F.2
Campbell, J.J.3
von Andrian, U.H.4
Szabo, M.C.5
Hasslen, S.R.6
Nelson, R.D.7
-
18
-
-
0017088029
-
Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high endothelial venules
-
Stamper, H. B. J. and Woodruff, J. J., Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high endothelial venules. J. Exp. Med. 1976. 144: 828.
-
(1976)
J. Exp. Med.
, vol.144
, pp. 828
-
-
Stamper, H.B.J.1
Woodruff, J.J.2
-
19
-
-
0025318296
-
Expression of low levels of peripheral lymph node-associated vascular addressin in mucosal lymphoid tissues: possible relevance to the dissemination of passaged AKR lymphomas
-
Bargatze, R. F., Streeter, P. R. and Butcher, E. C., Expression of low levels of peripheral lymph node-associated vascular addressin in mucosal lymphoid tissues: possible relevance to the dissemination of passaged AKR lymphomas. J. Cell Biochem. 1990. 42: 219-227.
-
(1990)
J. Cell Biochem.
, vol.42
, pp. 219-227
-
-
Bargatze, R.F.1
Streeter, P.R.2
Butcher, E.C.3
-
20
-
-
85047682713
-
Alpha4-integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels
-
Vajkoczy, P., Laschinger, M. and Engelhardt, B., Alpha4-integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels. J. Clin. Invest. 2001. 108: 557-565.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 557-565
-
-
Vajkoczy, P.1
Laschinger, M.2
Engelhardt, B.3
-
21
-
-
33646468932
-
Reevaluation of P-selectin and alpha 4 integrin as targets for the treatment of experimental autoimmune encephalomyelitis
-
Kerfoot, S. M., Norman, M. U., Lapointe, B. M., Bonder, C. S., Zbytnuik, L. and Kubes, P., Reevaluation of P-selectin and alpha 4 integrin as targets for the treatment of experimental autoimmune encephalomyelitis. J. Immunol. 2006. 176: 6225-6234.
-
(2006)
J. Immunol.
, vol.176
, pp. 6225-6234
-
-
Kerfoot, S.M.1
Norman, M.U.2
Lapointe, B.M.3
Bonder, C.S.4
Zbytnuik, L.5
Kubes, P.6
-
22
-
-
60549086393
-
beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity
-
Bauer, M., Brakebusch, C., Coisne, C., Sixt, M., Wekerle, H., Engelhardt, B. and Fassler, R., beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity. Proc. Natl. Acad. Sci. USA 2009. 106: 1920-1925.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 1920-1925
-
-
Bauer, M.1
Brakebusch, C.2
Coisne, C.3
Sixt, M.4
Wekerle, H.5
Engelhardt, B.6
Fassler, R.7
-
23
-
-
0032053668
-
Adhesion molecule phenotype of T lymphocytes in inflamed CNS
-
Engelhardt, B., Martin-Simonet, M. T., Rott, L. S., Butcher, E. C. and Michie, S. A., Adhesion molecule phenotype of T lymphocytes in inflamed CNS. J. Neuroimmunol. 1998. 84: 92-104.
-
(1998)
J. Neuroimmunol.
, vol.84
, pp. 92-104
-
-
Engelhardt, B.1
Martin-Simonet, M.T.2
Rott, L.S.3
Butcher, E.C.4
Michie, S.A.5
-
24
-
-
0028951825
-
Lymphocytes infiltrating the CNS during inflammation display a distinctive phenotype and bind to VCAM-1 but not to MAdCAM-1
-
Engelhardt, B., Conley, F. K., Kilshaw, P. J. and Butcher, E. C., Lymphocytes infiltrating the CNS during inflammation display a distinctive phenotype and bind to VCAM-1 but not to MAdCAM-1. Int. Immunol. 1995. 7: 481-491.
-
(1995)
Int. Immunol.
, vol.7
, pp. 481-491
-
-
Engelhardt, B.1
Conley, F.K.2
Kilshaw, P.J.3
Butcher, E.C.4
-
25
-
-
34247890248
-
DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27
-
Sigmundsdottir, H., Pan, J., Debes, G. F., Alt, C., Habtezion, A., Soler, D. and Butcher, E. C., DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27. Nat. Immunol. 2007. 8: 285-293.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 285-293
-
-
Sigmundsdottir, H.1
Pan, J.2
Debes, G.F.3
Alt, C.4
Habtezion, A.5
Soler, D.6
Butcher, E.C.7
-
26
-
-
5644300399
-
Retinoic acid imprints gut-homing specificity on T cells
-
Iwata, M., Hirakiyama, A., Eshima, Y., Kagechika, H., Kato, C. and Song, S. Y., Retinoic acid imprints gut-homing specificity on T cells. Immunity 2004. 21: 527-538.
-
(2004)
Immunity
, vol.21
, pp. 527-538
-
-
Iwata, M.1
Hirakiyama, A.2
Eshima, Y.3
Kagechika, H.4
Kato, C.5
Song, S.Y.6
-
27
-
-
0036791004
-
Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells
-
Lehmann, J., Huehn, J., de la Rosa, M., Maszyna, F., Kretschmer, U., Krenn, V., Brunner, M. et al., Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells. Proc. Natl. Acad. Sci. USA 2002. 99: 13031-13036.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13031-13036
-
-
Lehmann, J.1
Huehn, J.2
de la Rosa, M.3
Maszyna, F.4
Kretschmer, U.5
Krenn, V.6
Brunner, M.7
-
28
-
-
0035005143
-
Migratory activity and functional changes of green fluorescent effector cells before and during experimental autoimmune encephalomyelitis
-
Flugel, A., Berkowicz, T., Ritter, T., Labeur, M., Jenne, D. E., Li, Z., Ellwart, J. W. et al., Migratory activity and functional changes of green fluorescent effector cells before and during experimental autoimmune encephalomyelitis. Immunity 2001. 14: 547-560.
-
(2001)
Immunity
, vol.14
, pp. 547-560
-
-
Flugel, A.1
Berkowicz, T.2
Ritter, T.3
Labeur, M.4
Jenne, D.E.5
Li, Z.6
Ellwart, J.W.7
-
29
-
-
0036625019
-
Total body irradiation causes profound changes in endothelial traffic molecules for hematopoietic progenitor cell recruitment to bone marrow
-
Mazo, I. B., Quackenbush, E. J., Lowe, J. B. and von Andrian, U. H., Total body irradiation causes profound changes in endothelial traffic molecules for hematopoietic progenitor cell recruitment to bone marrow. Blood 2002. 99: 4182-4191.
-
(2002)
Blood
, vol.99
, pp. 4182-4191
-
-
Mazo, I.B.1
Quackenbush, E.J.2
Lowe, J.B.3
von Andrian, U.H.4
-
30
-
-
23244449103
-
P-selectin glycoprotein ligand 1 is not required for the development of experimental autoimmune encephalomyelitis in SJL and C57BL/6 mice
-
Engelhardt, B., Kempe, B., Merfeld-Clauss, S., Laschinger, M., Furie, B., Wild, M. K. and Vestweber, D., P-selectin glycoprotein ligand 1 is not required for the development of experimental autoimmune encephalomyelitis in SJL and C57BL/6 mice. J. Immunol. 2005. 175: 1267-1275.
-
(2005)
J. Immunol.
, vol.175
, pp. 1267-1275
-
-
Engelhardt, B.1
Kempe, B.2
Merfeld-Clauss, S.3
Laschinger, M.4
Furie, B.5
Wild, M.K.6
Vestweber, D.7
-
31
-
-
51149089536
-
Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node
-
Pfeiffer, F., Kumar, V., Butz, S., Vestweber, D., Imhof, B. A., Stein, J. V. and Engelhardt, B., Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node. Eur. J. Immunol. 2008. 38: 2142-2155.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 2142-2155
-
-
Pfeiffer, F.1
Kumar, V.2
Butz, S.3
Vestweber, D.4
Imhof, B.A.5
Stein, J.V.6
Engelhardt, B.7
-
32
-
-
0036687120
-
Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis
-
Alt, C., Laschinger, M. and Engelhardt, B., Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis. Eur. J. Immunol. 2002. 32: 2133-2144.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2133-2144
-
-
Alt, C.1
Laschinger, M.2
Engelhardt, B.3
-
33
-
-
0023598398
-
High endothelial venule binding as a predictor of the dissemination of passaged murine lymphomas
-
Bargatze, R. F., Wu, N. W., Weissman, I. L. and Butcher, E. C., High endothelial venule binding as a predictor of the dissemination of passaged murine lymphomas. J. Exp. Med. 1987. 166: 1125-1131.
-
(1987)
J. Exp. Med.
, vol.166
, pp. 1125-1131
-
-
Bargatze, R.F.1
Wu, N.W.2
Weissman, I.L.3
Butcher, E.C.4
-
34
-
-
40049095589
-
E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice
-
Doring, A., Wild, M., Vestweber, D., Deutsch, U. and Engelhardt, B., E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice. J. Immunol. 2007. 179: 8470-8479.
-
(2007)
J. Immunol.
, vol.179
, pp. 8470-8479
-
-
Doring, A.1
Wild, M.2
Vestweber, D.3
Deutsch, U.4
Engelhardt, B.5
|