메뉴 건너뛰기




Volumn 24, Issue 1, 2011, Pages 45-56

Broad humoral and cellular immunity elicited by a bivalent DNA vaccine encoding HA and NP cenes from an H5N1 virus

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; GAMMA INTERFERON; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; INTERLEUKIN 4; VIRUS ANTIBODY; VIRUS NUCLEOPROTEIN;

EID: 79951785009     PISSN: 08828245     EISSN: None     Source Type: Journal    
DOI: 10.1089/vim.2010.0056     Document Type: Article
Times cited : (41)

References (58)
  • 1
    • 0031753867 scopus 로고    scopus 로고
    • Gene transfer into muscle by electroporation in vivo
    • Aihara H, and Miyazaki J: Gene transfer into muscle by electroporation in vivo. Nat Biotechnol 1998;16:867-870. (Pubitemid 28405859)
    • (1998) Nature Biotechnology , vol.16 , Issue.9 , pp. 867-870
    • Aihara, H.1    Miyazaki, J.-I.2
  • 2
    • 0037056017 scopus 로고    scopus 로고
    • Electroporation improves the efficacy of DNA vaccines in large animals
    • DOI 10.1016/S0264-410X(02)00269-4, PII S0264410X02002694
    • Babiuk S, Baca-Estrada ME, Foldvari M, Storms M, Rabussay D, Widera G, and Babiuk LA: Electroporation improves the efficacy of DNA vaccines in large animals. Vaccine 2002;20:3399-3408. (Pubitemid 35245823)
    • (2002) Vaccine , vol.20 , Issue.27-28 , pp. 3399-3408
    • Babiuk, S.1    Baca-Estrada, M.E.2    Foldvari, M.3    Storms, M.4    Rabussay, D.5    Widera, G.6    Babiuk, L.A.7
  • 3
    • 57049087447 scopus 로고    scopus 로고
    • Conserved amino acids W423 and N424 in receptor-binding domain of SARS-CoV are potential targets for therapeutic monoclonal antibody
    • Bian C, Zhang X, Cai X, et al.: Conserved amino acids W423 and N424 in receptor-binding domain of SARS-CoV are potential targets for therapeutic monoclonal antibody. Virology 2009;383:39-46.
    • (2009) Virology , vol.383 , pp. 39-46
    • Bian, C.1    Zhang, X.2    Cai, X.3
  • 4
    • 27744516042 scopus 로고    scopus 로고
    • Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003
    • Butt KM, Smith GJ, Chen H, et al.: Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003. J Clin Microbiol 2005;43:5760-5767.
    • (2005) J Clin Microbiol , vol.43 , pp. 5760-5767
    • Butt, K.M.1    Smith, G.J.2    Chen, H.3
  • 5
    • 56149123448 scopus 로고    scopus 로고
    • A novel role for non-neutralizing antibodies against nucleoprotein in facilitating resistance to influenza virus
    • Carragher DM, Kaminski DA, Moquin A, Hartson L, and Randall TD: A novel role for non-neutralizing antibodies against nucleoprotein in facilitating resistance to influenza virus. J Immunol 2008;181:4168-4176.
    • (2008) J Immunol , vol.181 , pp. 4168-4176
    • Carragher, D.M.1    Kaminski, D.A.2    Moquin, A.3    Hartson, L.4    Randall, T.D.5
  • 6
    • 0033934281 scopus 로고    scopus 로고
    • Continued circulation in China of highly pathogenic avian influenza viruses encoding the hemagglutinin gene associated with the 1997 H5N1 outbreak in poultry and humans
    • DOI 10.1128/JVI.74.14.6592-6599.2000
    • Cauthen A, Swayne D, Schultz-Cherry S, Perdue M, and Suarez D: Continued circulation in China of highly pathogenic avian influenza viruses encoding the hemagglutinin gene associated with the 1997 H5N1 outbreak in poultry and humans. J Virol 2000;74:6592-6599. (Pubitemid 30429828)
    • (2000) Journal of Virology , vol.74 , Issue.14 , pp. 6592-6599
    • Cauthen, A.N.1    Swayne, D.E.2    Schultz-Cherry, S.3    Perdue, M.L.4    Suarez, D.L.5
  • 7
    • 65249188436 scopus 로고    scopus 로고
    • Swine influenza (H1N1) infection in two children
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention: Swine influenza (H1N1) infection in two children. MMWR Morb Mortal Wkly Rep 2009;58:400-402.
    • (2009) MMWR Morb Mortal Wkly Rep , vol.58 , pp. 400-402
  • 8
    • 22244450337 scopus 로고    scopus 로고
    • Protection against influenza virus infection in BALB/c mice immunized with a single dose of neuraminidase-expressing DNAs by electroporation
    • DOI 10.1016/j.vaccine.2005.03.035, PII S0264410X05004317
    • Chen J, Fang F, Li X, Chang H, and Chen Z: Protection against influenza virus infection in BALB/c mice immunized with a single dose of neuraminidase-expressing DNAs by electroporation. Vaccine 2005;23:4322-4328. (Pubitemid 40991237)
    • (2005) Vaccine , vol.23 , Issue.34 , pp. 4322-4328
    • Chen, J.1    Fang, F.2    Li, X.3    Chang, H.4    Chen, Z.5
  • 9
    • 51649100250 scopus 로고    scopus 로고
    • A consensus-hemagglutinin- based DNA vaccine that protects mice against divergent H5N1 influenza viruses
    • Chen MW, Cheng TJ, Huang Y, et al.: A consensus-hemagglutinin- based DNA vaccine that protects mice against divergent H5N1 influenza viruses. Proc Natl Acad Sci USA 2008;105:13538-13543.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13538-13543
    • Chen, M.W.1    Cheng, T.J.2    Huang, Y.3
  • 10
    • 0034257192 scopus 로고    scopus 로고
    • Cross-protection against a lethal influenza virus infection by DNA vaccine to neuraminidase
    • PII S0264410X00001493
    • Chen Z, Kadowaki S, Hagiwara Y, Yoshikawa T, Matsuo K, Kurata T, and Tamura S: Cross-protection against a lethal influenza virus infection by DNA vaccine to neuraminidase. Vaccine 2000;18:3214-3222. (Pubitemid 30408197)
    • (2000) Vaccine , vol.18 , Issue.28 , pp. 3214-3222
    • Chen, Z.1    Kadowaki, S.-E.2    Hagiwara, Y.3    Yoshikawa, T.4    Matsuo, K.5    Kurata, T.6    Tamura, S.-I.7
  • 11
    • 0030892146 scopus 로고    scopus 로고
    • Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry
    • Chen Z, Zhou P, Ho DD, Landau NR, and Marx PA: Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry. J Virol 1997;71:2705-2714. (Pubitemid 27119907)
    • (1997) Journal of Virology , vol.71 , Issue.4 , pp. 2705-2714
    • Chen, Z.1    Zhou, P.2    Ho, D.D.3    Landau, N.R.4    Marx, P.A.5
  • 12
    • 0032515638 scopus 로고    scopus 로고
    • Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus
    • Claas ECJ: Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus. Lancet 1998;351:472-477.
    • (1998) Lancet , vol.351 , pp. 472-477
    • Claas, E.C.J.1
  • 13
    • 0037080026 scopus 로고    scopus 로고
    • Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus
    • Coles RM, Mueller SN, Heath WR, Carbone FR, and Brooks AG: Progression of armed CTL from draining lymph node to spleen shortly after localized infection with herpes simplex virus 1. J Immunol 2002;168:834-838. (Pubitemid 34049585)
    • (2002) Journal of Immunology , vol.168 , Issue.2 , pp. 834-838
    • Coles, R.M.1    Mueller, S.N.2    Heath, W.R.3    Carbone, F.R.4    Brooks, A.G.5
  • 14
    • 16544368163 scopus 로고    scopus 로고
    • An overview of serum antibody responses to influenza virus antigens
    • Basel
    • Couch RB: An overview of serum antibody responses to influenza virus antigens. Dev Biol (Basel) 2003;115:25-30.
    • (2003) Dev Biol , vol.115 , pp. 25-30
    • Couch, R.B.1
  • 15
    • 79951787867 scopus 로고    scopus 로고
    • Intramuscular and intradermal injection of DNA vaccine in mice and primates methods in molecular medicine
    • Davis HL: Intramuscular and intradermal injection of DNA vaccine in mice and primates methods in molecular medicine. DNA Vaccine Methods Protocols 29.
    • DNA Vaccine Methods Protocols , vol.29
    • Davis, H.L.1
  • 17
    • 0031568653 scopus 로고    scopus 로고
    • MHC Affinity, Peptide Liberation, T Cell Repertoire, and Immunodominance All Contribute to the Paucity of MHC Class I-Restricted Peptides Recognized by Antiviral CTL
    • Deng Y, Yewdell JW, Eisenlohr LC, and Bennink JR: MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL. J Immunol 1997;158:1507-1515. (Pubitemid 127469502)
    • (1997) Journal of Immunology , vol.158 , Issue.4 , pp. 1507-1515
    • Deng, Y.1    Yewdell, J.W.2    Eisenlohr, L.C.3    Bennink, J.R.4
  • 19
    • 0029051152 scopus 로고
    • Preclinical efficacy of a prototype DNA vaccine: Enhanced protection against antigenic drift in influenza virus
    • Donnelly JJ, Friedman A, Martinez D, et al.: Preclinical efficacy of a prototype DNA vaccine: enhanced protection against antigenic drift in influenza virus. Nat Med 1995;1:583-587.
    • (1995) Nat Med , vol.1 , pp. 583-587
    • Donnelly, J.J.1    Friedman, A.2    Martinez, D.3
  • 20
    • 0030802996 scopus 로고    scopus 로고
    • Further protection against antigenic drift of influenza virus in a ferret model by DNA vaccination
    • DOI 10.1016/S0264-410X(96)00268-X, PII S0264410X9600268X
    • Donnelly JJ, Friedman A, Ulmer JB, and Liu MA: Further protection against antigenic drift of influenza virus in a ferret model by DNA vaccination. Vaccine 1997;15:865-868. (Pubitemid 27287977)
    • (1997) Vaccine , vol.15 , Issue.8 , pp. 865-868
    • Donnelly, J.J.1    Friedman, A.2    Ulmer, J.B.3    Liu, M.A.4
  • 22
    • 0036686714 scopus 로고    scopus 로고
    • DNA vaccine expressing conserved influenza virus proteins protective against H5N1 challenge infection in mice
    • Epstein SL, Tumpey TM, Misplon JA, et al.: DNA vaccine expressing conserved influenza virus proteins protective against H5N1 challenge infection in mice. Emerg Infect Dis 2002;8:796-801.
    • (2002) Emerg Infect Dis , vol.8 , pp. 796-801
    • Epstein, S.L.1    Tumpey, T.M.2    Misplon, J.A.3
  • 23
    • 67249138142 scopus 로고    scopus 로고
    • Pandemic potential of a strain of influenza A (H1N1): Early findings
    • Fraser C, Donnelly CA, Cauchemez S, et al.: Pandemic potential of a strain of influenza A (H1N1): early findings. Science 2009;324:1557-1561.
    • (2009) Science , vol.324 , pp. 1557-1561
    • Fraser, C.1    Donnelly, C.A.2    Cauchemez, S.3
  • 25
    • 67650407532 scopus 로고    scopus 로고
    • Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans
    • Garten RJ, Davis CT, Russell CA, et al.: Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science 2009;325:197-201.
    • (2009) Science , vol.325 , pp. 197-201
    • Garten, R.J.1    Davis, C.T.2    Russell, C.A.3
  • 27
    • 13844298849 scopus 로고    scopus 로고
    • Induction of Th1 type response by DNA vaccinations with N, M, and E genes against SARSCoV in mice
    • Jin H, Xiao C, Chen Z, et al.: Induction of Th1 type response by DNA vaccinations with N, M, and E genes against SARSCoV in mice. Biochem Biophys Res Commun 2005;328:979-986.
    • (2005) Biochem Biophys Res Commun , vol.328 , pp. 979-986
    • Jin, H.1    Xiao, C.2    Chen, Z.3
  • 28
    • 0030296823 scopus 로고    scopus 로고
    • Immunization with dissociated neuraminidase, matrix, and nucleoproteins from influenza A virus eliminates cognate help and antigenic competition
    • DOI 10.1006/viro.1996.0581
    • Johansson BE, and Kilbourne ED: Immunization with dissociated neuraminidase, matrix, and nucleoproteins from influenza A virus eliminates cognate help and antigenic competition. Virology 1996;225:136-144. (Pubitemid 26390059)
    • (1996) Virology , vol.225 , Issue.1 , pp. 136-144
    • Johansson, B.E.1    Kilbourne, E.D.2
  • 29
    • 0033055999 scopus 로고    scopus 로고
    • DNA vaccine encoding hemagglutinin provides protective immunity against H5N1 influenza virus infection in mice
    • Kodihalli S, Goto H, Kobasa DL, Krauss S, Kawaoka Y, and Webster RG: DNA vaccine encoding hemagglutinin provides protective immunity against H5N1 influenza virus infection in mice. J Virol 1999;73:2094-2098. (Pubitemid 29098113)
    • (1999) Journal of Virology , vol.73 , Issue.3 , pp. 2094-2098
    • Kodihalli, S.1    Goto, H.2    Kobasa, D.L.3    Krauss, S.4    Kawaoka, Y.5    Webster, R.G.6
  • 30
    • 0030893680 scopus 로고    scopus 로고
    • Cross-protection among lethal H5N2 influenza viruses induced by DNA vaccine to the hemagglutinin
    • Kodihalli S, Haynes JR, Robinson HL, and Webster RG: Cross-protection among lethal H5N2 influenza viruses induced by DNA vaccine to the hemagglutinin. J Virol 1997;71:3391-3396. (Pubitemid 27172347)
    • (1997) Journal of Virology , vol.71 , Issue.5 , pp. 3391-3396
    • Kodihalli, S.1    Haynes, J.R.2    Robinson, H.L.3    Webster, R.G.4
  • 33
    • 0032534058 scopus 로고    scopus 로고
    • Differentiation of naive CTL to effector and memory CTL: Correlation of effector function with phenotype and cell division
    • Oehen S, and Brduscha-Riem K: Differentiation of naive CTL to effector and memory CTL: correlation of effector function with phenotype and cell division. J Immunol 1998;161:5338-5346. (Pubitemid 28519094)
    • (1998) Journal of Immunology , vol.161 , Issue.10 , pp. 5338-5346
    • Oehen, S.1    Brduscha-Riem, K.2
  • 35
    • 0025833701 scopus 로고
    • Localization of the influenza virus nucleoprotein: Cell-associated and extracellular non-virion forms
    • Prokudina EN, and Semenova NP: Localization of the influenza virus nucleoprotein: cell-associated and extracellular non-virion forms. J Gen Virol 1991;72(Pt 7):1699-1702.
    • (1991) J Gen Virol , vol.72 , Issue.PART 7 , pp. 1699-1702
    • Prokudina, E.N.1    Semenova, N.P.2
  • 36
    • 33748562649 scopus 로고    scopus 로고
    • Crossing the species barrier: The threat of an avian influenza pandemic
    • Riedel S: Crossing the species barrier: the threat of an avian influenza pandemic. Proc (Bayl Univ Med Cent) 2006;19:16-20.
    • (2006) Proc (Bayl Univ Med Cent) , vol.19 , pp. 16-20
    • Riedel, S.1
  • 37
    • 0027213712 scopus 로고
    • Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA
    • DOI 10.1016/0264-410X(93)90385-B
    • Robinson HL, Hunt LA, and Webster RG: Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA. Vaccine 1993;11:957-960. (Pubitemid 23218805)
    • (1993) Vaccine , vol.11 , Issue.9 , pp. 957-960
    • Robinson, H.L.1    Hunt, L.A.2    Webster, R.G.3
  • 39
    • 0025338171 scopus 로고
    • Characterization and immunological properties of influenza A virus nucleoprotein (NP): Cell-associated NP isolated from infected cells or viral NP expressed by vaccinia recombinant virus do not confer protection
    • Stitz L, Schmitz C, Binder D, Zinkernagel R, Paoletti E, and Becht H: Characterization and immunological properties of influenza A virus nucleoprotein (NP): cell-associated NP isolated from infected cells or viral NP expressed by vaccinia recombinant virus do not confer protection. J Gen Virol 1990;71(Pt 5):1169-1179. (Pubitemid 20174357)
    • (1990) Journal of General Virology , vol.71 , Issue.5 , pp. 1169-1179
    • Stitz, L.1    Schmitz, C.2    Binder, D.3    Zinkernagel, R.4    Paoletti, E.5    Becht, H.6
  • 40
    • 14444284599 scopus 로고    scopus 로고
    • Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness
    • Subbarao, K: Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Science 1998;279:393-396.
    • (1998) Science , vol.279 , pp. 393-396
    • Subbarao, K.1
  • 41
    • 0037227584 scopus 로고    scopus 로고
    • Evaluation of a genetically modified reassortant H5N1 influenza a virus vaccine candidate generated by plasmid-based reverse genetics
    • DOI 10.1006/viro.2002.1742
    • Subbarao K, Chen H, Swayne D, et al.: Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics. Virology 2003;305:192-200. (Pubitemid 36062823)
    • (2003) Virology , vol.305 , Issue.1 , pp. 192-200
    • Subbarao, K.1    Chen, H.2    Swayne, D.3    Mingay, L.4    Fodor, E.5    Brownlee, G.6    Xu, X.7    Lu, X.8    Katz, J.9    Cox, N.10    Matsuoka, Y.11
  • 42
    • 0037056026 scopus 로고    scopus 로고
    • Improved cellular and humoral immune responses against Mycobacterium tuberculosis antigens after intramuscular DNA immunisation combined with muscle electroporation
    • DOI 10.1016/S0264-410X(02)00289-X, PII S0264410X0200289X
    • Tollefsen S, Tjelle T, Schneider J, et al.: Improved cellular and humoral immune responses against Mycobacterium tuberculosis antigens after intramuscular DNA immunisation combined with muscle electroporation. Vaccine 2002;20:3370-3378. (Pubitemid 35256081)
    • (2002) Vaccine , vol.20 , Issue.27-28 , pp. 3370-3378
    • Tollefsen, S.1    Tjelle, T.E.2    Schneider, J.3    Harboe, M.4    Wiker, H.G.5    Hewinson, G.6    Huygen, K.7    Mathiesen, I.8
  • 43
    • 70350574663 scopus 로고    scopus 로고
    • Measurement of neutralizing antibody responses against H5N1 clades in immunized mice and ferrets using pseudotypes expressing influenza hemagglutinin and neuraminidase
    • Tsai C, Caillet C, Hu H, et al.: Measurement of neutralizing antibody responses against H5N1 clades in immunized mice and ferrets using pseudotypes expressing influenza hemagglutinin and neuraminidase. Vaccine 2009;27:6777-6790.
    • (2009) Vaccine , vol.27 , pp. 6777-6790
    • Tsai, C.1    Caillet, C.2    Hu, H.3
  • 44
    • 0037095578 scopus 로고    scopus 로고
    • Influenza DNA vaccines
    • Ulmer JB: Influenza DNA vaccines. Vaccine 2002;20(Suppl 2):S74-S76.
    • (2002) Vaccine , vol.20 , Issue.SUPPL. 2
    • Ulmer, J.B.1
  • 45
    • 0028130518 scopus 로고
    • Protective immunity by intramuscular injection of low doses of influenza virus DNA vaccines
    • DOI 10.1016/0264-410X(94)90081-7
    • Ulmer JB, Deck RR, DeWitt CM, Friedman A, Donnelly JJ, and Liu MA: Protective immunity by intramuscular injection of low doses of influenza virus DNA vaccines. Vaccine 1994;12:1541-1544. (Pubitemid 24360571)
    • (1994) Vaccine , vol.12 , Issue.16 , pp. 1541-1544
    • Ulmer, J.M.1    Deck, R.R.2    DeWitt, C.M.3    Friedman, A.4    Donnelly, J.J.5    Liu, M.A.6
  • 48
    • 0017333509 scopus 로고
    • Early presence of ribonucleoprotein antigen on surface of influenza virus infected cells
    • Virelizier JL, Allison AC, Oxford JS, and Schild GC: Early presence of ribonucleoprotein antigen on surface of influenza virus-infected cells. Nature 1977;266:52-54. (Pubitemid 8050009)
    • (1977) Nature , vol.266 , Issue.5597 , pp. 52-54
    • Virelizier, J.L.1    Allison, A.C.2    Oxford, J.S.3    Schild, G.C.4
  • 49
    • 4644371368 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Electroporation and other physical methods
    • Wells DJ: Gene therapy progress and prospects: electroporation and other physical methods. Gene Ther 2004;11:1363-1369.
    • (2004) Gene Ther , vol.11 , pp. 1363-1369
    • Wells, D.J.1
  • 51
    • 65549153022 scopus 로고    scopus 로고
    • New influenza (H1N1) virus infections: Global surveillance summary
    • World Health Organization
    • World Health Organization: New influenza (H1N1) virus infections: global surveillance summary. Wkly Epidemiol Rec 2009;84.
    • (2009) Wkly Epidemiol Rec , vol.84
  • 54
    • 33144461911 scopus 로고    scopus 로고
    • Avian influenza virus infections in humans
    • DOI 10.1378/chest.129.1.156
    • Wong SS, and Yuen KY: Avian influenza virus infections in humans. Chest 2006;129:156-168. (Pubitemid 43265257)
    • (2006) Chest , vol.129 , Issue.1 , pp. 156-168
    • Wong, S.S.Y.1    Yuen, K.-Y.2
  • 55
    • 4844227626 scopus 로고    scopus 로고
    • From lethal virus to life-saving vaccine: Developing inactivated vaccines for pandemic influenza
    • DOI 10.1038/nrmicro979
    • Wood JM, and Robertson JS: From lethal virus to life-saving vaccine: developing inactivated vaccines for pandemic influenza. Nat Rev Microbiol 2004;2:842-847. (Pubitemid 39317465)
    • (2004) Nature Reviews Microbiology , vol.2 , Issue.10 , pp. 842-847
    • Wood, J.M.1    Robertson, J.S.2
  • 56
    • 34547886820 scopus 로고    scopus 로고
    • Immunization by avian H5 influenza hemagglutinin mutants with altered receptor binding specificity
    • DOI 10.1126/science.1135165
    • Yang ZY, Wei CJ, Kong WP, Wu L, Xu L, Smith DF, and Nabel GJ: Immunization by avian H5 influenza hemagglutinin mutants with altered receptor binding specificity. Science 2007;317:825-828. (Pubitemid 47257924)
    • (2007) Science , vol.317 , Issue.5839 , pp. 825-828
    • Yang, Z.-Y.1    Wei, C.-J.2    Kong, W.-P.3    Wu, L.4    Xu, L.5    Smith, D.F.6    Nabel, G.J.7
  • 58
    • 61949233370 scopus 로고    scopus 로고
    • A single immunization with HA DNA vaccine by electroporation induces early protection against H5N1 avian influenza virus challenge in mice
    • Zheng L, Wang F, Yang Z, Chen J, Chang H, and Chen Z: A single immunization with HA DNA vaccine by electroporation induces early protection against H5N1 avian influenza virus challenge in mice. BMC Infect Dis 2009;9:17.
    • (2009) BMC Infect Dis , vol.9 , pp. 17
    • Zheng, L.1    Wang, F.2    Yang, Z.3    Chen, J.4    Chang, H.5    Chen, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.