-
1
-
-
22144464869
-
Relation of chronic and acute glycemic control on mortality in acute myocardial infarction with diabetes Mellitus
-
DOI 10.1016/j.amjcard.2005.03.040, PII S0002914905006454
-
Cao, J. J.; Hudson, M.; Jankowski, M.; Whitehouse, F.; Weaver, W. D. Relation of chronic and acute glycemic control on mortality in acute myocardial infarction with diabetes mellitus. Am. J. Cardiol., 2005, 96(2), 183-186. (Pubitemid 40978570)
-
(2005)
American Journal of Cardiology
, vol.96
, Issue.2
, pp. 183-186
-
-
Cao, J.J.1
Hudson, M.2
Jankowski, M.3
Whitehouse, F.4
Weaver, W.D.5
-
2
-
-
0037472879
-
Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes
-
DOI 10.1056/NEJMoa021778
-
Gaede, P.; Vedel, P.; Larsen, N.; Jensen, G.. V.; Parving, H. H.; Pedersen, O. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N. Engl. J. Med., 2003, 348(5), 383-393. (Pubitemid 36159355)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.5
, pp. 383-393
-
-
Gaede, P.1
Vedel, P.2
Larsen, N.3
Jensen, G.V.H.4
Parving, H.-H.5
Pedersen, O.6
-
3
-
-
0036206555
-
Attenuating CV risk factors in patients with diabetes: Clinical evidence to clinical practice
-
Garber, A. J. Attenuating CV risk factors in patients with diabetes: clinical evidence to clinical practice. Diabetes. Obes. Metab., 2002, 4, S5-12. (Pubitemid 34285274)
-
(2002)
Diabetes, Obesity and Metabolism
, vol.4
, Issue.SUPPL. 1
-
-
Garber, A.J.1
-
4
-
-
0035724791
-
Vascular complications in diabetes and their prevention
-
Kassab, E.; McFarlane, S. I.; Sower, J. R. Vascular complications in diabetes and their prevention. Vasc. Med. 2001, 6(4), 249-255. (Pubitemid 34256766)
-
(2001)
Vascular Medicine
, vol.6
, Issue.4
, pp. 249-255
-
-
Kassab, E.1
McFarlane, S.I.2
Sowers, J.R.3
-
5
-
-
0027389773
-
Vascular thrombosis in type II diabetes mellitus
-
Colwell, J. A. Vascular thrombosis in type II diabetes mellitus. Diabetes, 1993, 42(1), 8-11. (Pubitemid 23013789)
-
(1993)
Diabetes
, vol.42
, Issue.1
, pp. 8-11
-
-
Colwell, J.A.1
-
6
-
-
45849107043
-
Clinical practice guidelines and clinical practice recommendations for diabetes and chronic kidney disease
-
Kidney Disease Outcomes Quality Initiative KDOQI
-
Kidney Disease Outcomes Quality Initiative (KDOQI). Clinical practice guidelines and clinical practice recommendations for diabetes and chronic kidney disease. Am. J. Kidney. Dis., 2007, 49(2), S62-S73.
-
(2007)
Am. J. Kidney. Dis.
, vol.49
, Issue.2
-
-
-
7
-
-
0030812652
-
Predialysis glycemic control is an independent predictor of clinical outcome in type II diabetics on continuous ambulatory peritoneal dialysis
-
Yu, C. C.; Wu, M. S.; Wu, C. H.; Young, C. W.; Huang, J. Y.; Hong, J. J.; Fan Cjiang, C. Y.; Leu, M. L.; Huang, C. C. Predialysis glycemic control is an independent predictor of clinical outcome in type II diabetics on continuous ambulatory peritoneal dialysis. Perit. Dial. Int., 1997, 17(3), 262-268.
-
(1997)
Perit. Dial. Int.
, vol.17
, Issue.3
, pp. 262-268
-
-
Yu, C.C.1
Wu, M.S.2
Wu, C.H.3
Young, C.W.4
Huang, J.Y.5
Hong, J.J.6
Fan Cjiang, C.Y.7
Leu, M.L.8
Huang, C.C.9
-
8
-
-
0035347825
-
Glycemic Control Is a Predictor of Survival for Diabetic Patients on Hemodialysis
-
Morioka, T.; Emoto, M.; Tabata, T.; Shoji, T.; Tahara, H.; Kishimoto, H.; Ishimura, E.; Nishizawa, Y. Glycemic control is a predictor of survival for diabetic patients on hemodialysis. Diabetes Care, 2001, 24(5), 909-913. (Pubitemid 33636068)
-
(2001)
Diabetes Care
, vol.24
, Issue.5
, pp. 909-913
-
-
Morioka, T.1
Emoto, M.2
Tabata, T.3
Shoji, T.4
Tahara, H.5
Kishimoto, H.6
Ishimura, E.7
Nishizawa, Y.8
-
9
-
-
20844435106
-
Oral antihyperglycemic agents and renal disease: New agents, new concepts
-
Yale, J. F. Oral antihyperglycemic agents and renal disease: new agents, new concepts. J. Am. Soc. Nephrol., 2005, 16, 7-10.
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 7-10
-
-
Yale, J.F.1
-
10
-
-
0021070744
-
Absorption and disposition of ibuprofen in hemodialyzed uremic patients
-
Senekjian, H. O.; Lee, C. S.; Kuo, T. H.; Au, D. S.; Krothapalli, R. Absorption and disposition of ibuprofen in hemodialyzed uremic patients. Eur. J. Rheumatol. Inflam. 1983, 6(2), 155-162. (Pubitemid 14191440)
-
(1983)
European Journal of Rheumatology and Inflammation
, vol.6
, Issue.2
, pp. 155-162
-
-
Senekjian, H.O.1
Lee, C.S.2
Kuo, T.H.3
-
11
-
-
0027715488
-
Pharmacokinetics of orally administered levocabastine in patients with renal insufficiency
-
Zazgornik, J.; Huang, M. L.; Van Peer, A.; Woestenborghs, R.; Heykants, J.; Stephen, A. Pharmacokinetics of orally administered levocabastine in patients with renal insufficiency. J. Clin. Pharmacol., 1993, 32(12), 1214-1218. (Pubitemid 24023686)
-
(1993)
Journal of Clinical Pharmacology
, vol.33
, Issue.12
, pp. 1214-1218
-
-
Zazgornik, J.1
Huang, M.L.2
Van Peer, A.3
Woestenborghs, R.4
Heykants, J.5
Stephen, A.6
-
12
-
-
0025757336
-
The effect of renal failure on hepatic drug clearance
-
Touchette, M. A.; Slaughter, R. L. The effect of renal failure on hepatic drug clearance. DICP, 1991, 25(11), 1214-1224.
-
(1991)
DICP
, vol.25
, Issue.11
, pp. 1214-1224
-
-
Touchette, M.A.1
Slaughter, R.L.2
-
13
-
-
37549020724
-
Effects of chronic renal failure on liver drug transporters
-
Naud, J.; Michaud, J.; Leblond, F. A.; Bernier, G.; Bonnardeaux, A.; Pichette, V. Effects of chronic renal failure on liver drug transporters. Drug. Metab. Dispos., 2008, 36(1), 124-128.
-
(2008)
Drug. Metab. Dispos.
, vol.36
, Issue.1
, pp. 124-128
-
-
Naud, J.1
Michaud, J.2
Leblond, F.A.3
Bernier, G.4
Bonnardeaux, A.5
Pichette, V.6
-
14
-
-
43949128108
-
Emerging evidence of the impact of kidney disease on drug metabolism and transport
-
DOI 10.1038/clpt.2008.59, PII CLPT200859
-
Nolin, T. D.; Naud, J.; Leblond, F. A.; Pichette, V. Emerging evidence of impacy of kidney disease on drug metabolism and transport. Clin. Pharmacol. Ther., 2008, 83(6) 898-903. (Pubitemid 351704931)
-
(2008)
Clinical Pharmacology and Therapeutics
, vol.83
, Issue.6
, pp. 898-903
-
-
Nolin, T.D.1
Naud, J.2
Leblond, F.A.3
Pichette, V.4
-
15
-
-
0142188758
-
Hepatic Drug Metabolism and Transport in Patients With Kidney Disease
-
Nolin, T. D.; Frye, R. F.; Matzke, G. R. Hepatic drug metabolism and transport in patients with kidney disease. Am. J. Kidney. Dis., 2003, 42(5), 906-925. (Pubitemid 37322908)
-
(2003)
American Journal of Kidney Diseases
, vol.42
, Issue.5
, pp. 906-925
-
-
Nolin, T.D.1
Frye, R.F.2
Matzke, G.R.3
-
16
-
-
28444444126
-
Effects of renal failure on drug transport and metabolism
-
DOI 10.1016/j.pharmthera.2005.05.010, PII S0163725805001543
-
Sun, H.; Frassetto, L.; Benet, L. Z. Effects of renal failure on drug transport and metabolism. Pharmacol. Ther., 2006, 109 (1-2), 1-11. (Pubitemid 41740811)
-
(2006)
Pharmacology and Therapeutics
, vol.109
, Issue.1-2
, pp. 1-11
-
-
Sun, H.1
Frassetto, L.2
Benet, L.Z.3
-
17
-
-
0015222511
-
The UGDP study
-
Salsburg, D. S. The UGDP study. JAMA, 1971, 218(11), 1704-1705.
-
(1971)
JAMA
, vol.218
, Issue.11
, pp. 1704-1705
-
-
Salsburg, D.S.1
-
18
-
-
0032511583
-
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
-
United Kingdom Prospective Diabetes Study Group UKPDS
-
United Kingdom Prospective Diabetes Study Group (UKPDS). Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet, 1998, 352(9131), 837-853.
-
(1998)
Lancet
, vol.352
, Issue.9131
, pp. 837-853
-
-
-
19
-
-
70449360911
-
Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial
-
ADVANCE Collaborative Group
-
Zoungas, S.; de Galan, B. E.; Ninomiya, T.; Grobbee, D.; Hamet, P.; Heller, S.; MacMahon, S.; Marre, M.; Neal, B.; Patel, A.; Woodward, M.; Chalmers, J.; ADVANCE Collaborative Group; Cass, A.; Glasziou, P.; Harrap, S.; Lisheng, L.; Mancia, G.; Pillai, A.; Poulter, N.; Perkovic, V.; Travert, F. Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial. Diabetes Care, 2009, 32(11), 2068-2074.
-
(2009)
Diabetes Care
, vol.32
, Issue.11
, pp. 2068-2074
-
-
Zoungas, S.1
Galan, B.E.2
Ninomiya, T.3
Grobbee, D.4
Hamet, P.5
Heller, S.6
MacMahon, S.7
Marre, M.8
Neal, B.9
Patel, A.10
Woodward, M.11
Chalmers, J.12
Cass, A.13
Glasziou, P.14
Harrap, S.15
Lisheng, L.16
Mancia, G.17
Pillai, A.18
Poulter, N.19
Perkovic, V.20
Travert, F.21
more..
-
20
-
-
0029857682
-
Pharmacokinetics and safety of glimepiride at clinically effective doses in diabetic patients with renal impairment
-
DOI 10.1007/s001250050624
-
Rosenkranz, B.; Profozic, V.; Metelko, Z.; Mizljak, V.; Lange, C.; Malerczyk V. Pharmacokinetics and safety of glimepiride at clinically effective doses in diabetic patients with renal impairment. Diabetologia, 1996, 39(12), 1617-1624. (Pubitemid 26397377)
-
(1996)
Diabetologia
, vol.39
, Issue.12
, pp. 1617-1624
-
-
Rosenkranz, B.1
Profozic, V.2
Metelko, Z.3
Mrzljak, V.4
Lange, C.5
Malerczyk, V.6
-
21
-
-
79951619696
-
-
Available from, Accessed October 1, 2010
-
Available from URL:http://www.pfizer.com/files/products/uspi-glipizide. pdf (Accessed October 1, 2010)
-
-
-
-
22
-
-
25844448609
-
Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: Effect of fibrates and rifampicin
-
DOI 10.1111/j.1742-7843.2005.pto-157.x
-
Kajosaari, L. I.; Laitila, J.; Neuvonen, P. J.; Backman, J. T. Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin. Basic Clin. Pharmacol. Toxicol., 2005, 97(4), 249-256. (Pubitemid 41433700)
-
(2005)
Basic and Clinical Pharmacology and Toxicology
, vol.97
, Issue.4
, pp. 249-256
-
-
Kajosaari, L.I.1
Laitila, J.2
Neuvonen, P.J.3
Backman, J.T.4
-
23
-
-
33644548936
-
Telithromycin, but not montelukast, increases the plasma concentrations and effects of the cytochrome P450 3A4 and 2C8 substrate repaglinide
-
Kajosaari, L. I.; Niemi, M.; Backman, J. T.; Neuvonen, P. J. Telithromycin, but not montelukast, increases the plasma concentrations and effects of the cytochrome P450 3A4 and 2C8 substrate repaglinide. Clin. Pharmacol. Ther., 2006, 79(39), 231-242.
-
(2006)
Clin. Pharmacol. Ther.
, vol.79
, Issue.39
, pp. 231-242
-
-
Kajosaari, L.I.1
Niemi, M.2
Backman, J.T.3
Neuvonen, P.J.4
-
24
-
-
23044456599
-
Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide
-
DOI 10.1111/j.1365-2125.2005.02385.x
-
Niemi, M.; Backman, J. T.; Juntti-Patinen, L.; Neuvonen, M.; Neuvonen, P. J. Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide. Br. J. Clin. Pharmacol., 2005, 60(2), 208-217. (Pubitemid 41075907)
-
(2005)
British Journal of Clinical Pharmacology
, vol.60
, Issue.2
, pp. 208-217
-
-
Niemi, M.1
Backman, J.T.2
Juntti-Patinen, L.3
Neuvonen, M.4
Neuvonen, P.J.5
-
25
-
-
0033950125
-
Pharmacokinetics of repaglinide in subjects with renal impairment
-
Murbury, T. C.; Ruckle, J. L.; Hatorp, V.; Andersen, M. P.; Nielsen, K. K.; Huang, W. X.; Strange, P. Pharmakokinetics of repaglinide in subjects with renal impairment. Clin. Pharmacol. Ther., 2000, 67(1), 7-15. (Pubitemid 30078382)
-
(2000)
Clinical Pharmacology and Therapeutics
, vol.67
, Issue.1
, pp. 7-15
-
-
Marbury, T.C.1
Ruckle, J.L.2
Hatorp, V.3
Andersen, M.P.4
Nielsen, K.K.5
Huang, W.C.6
Strange, P.7
-
26
-
-
34247137295
-
Carboxyl-glucuronidation of mitiglinide by human UDP- glucuronosyltransferases
-
DOI 10.1016/j.bcp.2007.02.004, PII S0006295207000913
-
Yu, L.; Lu, S.; Lin, Y.; Zeng, S. Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases. Biochem. Pharmacol., 2007, 73(11), 1842-1851. (Pubitemid 46601408)
-
(2007)
Biochemical Pharmacology
, vol.73
, Issue.11
, pp. 1842-1851
-
-
Yu, L.1
Lu, S.2
Lin, Y.3
Zeng, S.4
-
27
-
-
34247137295
-
Carboxyl-glucuronidation of mitiglinide by human UDP- glucuronosyltransferases
-
DOI 10.1016/j.bcp.2007.02.004, PII S0006295207000913
-
Yu, L.; Lu, S.; Lin, Y.; Zeng, S. Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases. Biochem. Pharmacol., 2007, 73, 1842-1851. (Pubitemid 46601408)
-
(2007)
Biochemical Pharmacology
, vol.73
, Issue.11
, pp. 1842-1851
-
-
Yu, L.1
Lu, S.2
Lin, Y.3
Zeng, S.4
-
28
-
-
0035072748
-
Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel
-
Reimann, F.; Proks, P.; Ashcroft, F. M. Effects of mitiglinide (S 21403) on Kir6.2/SURl, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel. Br. J. Pharmacol., 2001, 132(7), 1542-1548. (Pubitemid 32281043)
-
(2001)
British Journal of Pharmacology
, vol.132
, Issue.7
, pp. 1542-1548
-
-
Reimann, F.1
Proks, P.2
Ashcroft, F.M.3
-
29
-
-
69249220222
-
Addition of mitiglinide to pioglitazone monotherapy improves overall glycemic control in Japanese patients with type 2 diabetes: A randomized double blind trial
-
Kaku, K.; Tanaka, S.; Origasa, H.; Kikuchi, M.; Akanuma, Y. Addition of mitiglinide to pioglitazone monotherapy improves overall glycemic control in Japanese patients with type 2 diabetes: A randomized double blind trial. Endocr. J., 2009, 56(5), 657-664.
-
(2009)
Endocr. J
, vol.56
, Issue.5
, pp. 657-664
-
-
Kaku, K.1
Tanaka, S.2
Origasa, H.3
Kikuchi, M.4
Akanuma, Y.5
-
30
-
-
70349973565
-
Effect of mitiglinide on glycemic control over 52 weeks in Japanese type 2 diabetic patients insufficiently controlled with pioglitazone monotherapy
-
Kaku, K.; Tanaka, S.; Orisawa, H.; Kikuchi, M.; Akanuma, Y. Effect of mitiglinide on glycemic control over 52 weeks in Japanese type 2 diabetic patients insufficiently controlled with pioglitazone monotherapy. Endocr. J., 2009, 56(6), 739-746.
-
(2009)
Endocr. J
, vol.56
, Issue.6
, pp. 739-746
-
-
Kaku, K.1
Tanaka, S.2
Orisawa, H.3
Kikuchi, M.4
Akanuma, Y.5
-
31
-
-
70349260322
-
The mitiglinide versus nateglinide comparison group. Multicentre, double-blind, randomized study of mitiglinide comapared with nateglinide in type 2 diabetes mellitus patients in China
-
Gao, X. The mitiglinide versus nateglinide comparison group. Multicentre, double-blind, randomized study of mitiglinide comapared with nateglinide in type 2 diabetes mellitus patients in China. J. Int. Med. Res., 2009, 37(8), 812-821.
-
(2009)
J. Int. Med. Res.
, vol.37
, Issue.8
, pp. 812-821
-
-
Gao, X.1
-
32
-
-
76749162763
-
Combination therapy with mitiglinide and voglibose improves glycemic control in type 2 diabetic patients on hemodialysis
-
Abe, M.; Okada, K.; Maruyama, T.; Maruyama, N.; Maysumoto, K. Combination therapy with mitiglinide and voglibose improves glycemic control in type 2 diabetic patients on hemodialysis. Expert Opin. Pharmacother., 2010, 11(2), 169-176.
-
(2010)
Expert Opin. Pharmacother.
, vol.11
, Issue.2
, pp. 169-176
-
-
Abe, M.1
Okada, K.2
Maruyama, T.3
Maruyama, N.4
Maysumoto, K.5
-
33
-
-
77955827114
-
Efficacy and safety of mitiglinide in diabetic patients on maintenance hemodialysis
-
Abe, M.; Okada, K.; Maruyama, T.; Maruyama, N.; Maysumoto, K. Efficacy and safety of mitiglinide in diabetic patients on maintenance hemodialysis. Endcrine. J., 2010, 57(7), 581-588.
-
(2010)
Endcrine. J
, vol.57
, Issue.7
, pp. 581-588
-
-
Abe, M.1
Okada, K.2
Maruyama, T.3
Maruyama, N.4
Maysumoto, K.5
-
34
-
-
0031682113
-
The STOP-NIDDM trial: An international study on the efficacy of an α- glucosidase inhibitor to prevent type 2 diabetes in a population with impaired glucose tolerance: Rationale, design, and preliminary screening data
-
DOI 10.2337/diacare.21.10.1720
-
Chiasson, J. L.; Gomis, R.; Hanefeld, M.; Josse, R. G.; Karasik, A.; Laakso, M. The STOP-NIDDM Trial: an international study on the efficacy of an alpha-glucosidase inhibitor to prevent type 2 diabetes in a population with impaired glucose tolerance: rationale, design, and preliminary screening data. Study to Prevent Non-Insulin-Dependent Diabetes Mellitus. Diabetes Care, 1998, 21(10), 1720-1725. (Pubitemid 28449814)
-
(1998)
Diabetes Care
, vol.21
, Issue.10
, pp. 1720-1725
-
-
Chiasson, J.-L.1
Gomis, R.2
Hanefeld, M.3
Josse, R.G.4
Karasik, A.5
Laakso, M.6
-
35
-
-
0038455703
-
Acarbose Treatment and the Risk of Cardiovascular Disease and Hypertension in Patients with Impaired Glucose Tolerance: The STOP-NIDDM Trial
-
DOI 10.1001/jama.290.4.486
-
Chiasson, J. L.; Josse, R. G.; Gomis, R.; Hanefeld, M.; Karasik, A.; Laakso, M. Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial. JAMA, 2003, 290(4), 486-494. (Pubitemid 37430502)
-
(2003)
Journal of the American Medical Association
, vol.290
, Issue.4
, pp. 486-494
-
-
Chiasson, J.-L.1
Josse, R.G.2
Gomis, R.3
Hanefeld, M.4
Karasik, A.5
Laakso, M.6
-
36
-
-
35748959376
-
Combination therapy of pioglitazone with voglibose improves glycemic control safely and rapidly in Japanese type 2-diabetic patients on hemodialysis
-
Abe, M.; Kikuchi, F.; Kaizu, K.; Matsumoto, K. Combination therapy of pioglitazone with vogliboseimproves glycemic control safely and rapidly in Japanese type 2-diabetic patients on hemodialysis. Clin. Nephrol, 2007, 68(5), 287-294. (Pubitemid 350047761)
-
(2007)
Clinical Nephrology
, vol.68
, Issue.5
, pp. 287-294
-
-
Abe, M.1
Kikuchi, F.2
Kaizu, K.3
Matsumoto, K.4
-
37
-
-
79951633557
-
-
Available from, Accessed Jan 15, 2011
-
Available from URL:http://www.accessdata.fda.gov/drugsatfda-docs/label/ 2008/020482s023lbl.pdf (Accessed Jan 15, 2011).
-
-
-
-
38
-
-
79951640338
-
-
Available from, Accessed Jan 15, 2011
-
Available from URL:http://www.pfizer.com/files/products/uspiglyset.pdf (Accessed Jan 15, 2011).
-
-
-
-
39
-
-
0028963260
-
13; Relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed for three years
-
United Kingdom Prospective Diabetes Study Group UKPDS
-
United Kingdom Prospective Diabetes Study Group (UKPDS). 13; Relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed for three years. B. M. J., 1995, 310(6972), 83-88.
-
(1995)
B. M. J
, vol.310
, Issue.6972
, pp. 83-88
-
-
-
40
-
-
0032511566
-
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
-
United Kingdom Prospective Diabetes Study Group UKPDS
-
United Kingdom Prospective Diabetes Study Group (UKPDS). Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet, 1998, 352(9131), 854-865.
-
(1998)
Lancet
, vol.352
, Issue.9131
, pp. 854-865
-
-
-
41
-
-
0030605388
-
Metformin
-
Bailey, C. J.; Turner, R. C. Metformin. N. Engl. J. Med., 1996, 334(9), 574-579. (Pubitemid 126537875)
-
(1996)
New England Journal of Medicine
, vol.334
, Issue.9
, pp. 574-579
-
-
Bailey, C.J.1
Turner, R.C.2
-
42
-
-
0029819936
-
Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus
-
DOI 10.1210/jc.81.11.4059
-
Cusi, K.; Consoli, A.; DeFronzo, R. A. Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus. J. Clin. Endo. Met., 1996, 81(11), 4059-4067. (Pubitemid 26380418)
-
(1996)
Journal of Clinical Endocrinology and Metabolism
, vol.81
, Issue.11
, pp. 4059-4067
-
-
Cusi, K.1
Consoli, A.2
Defronzo, R.A.3
-
43
-
-
18144447850
-
Antiatherogenic properties of metformin: The experimental evidence
-
4 II
-
Mamputu, J. C.; Wiernsperger, N. F.; Renier, G. Antiatherogenic properties of metformin: the experimental evidence. Diabetes Metab., 2003, 29 (4 Pt 2), 6S71-76. (Pubitemid 37187093)
-
(2003)
Diabetes and Metabolism
, vol.29
-
-
Mamputu, J.C.1
Wiernsperger, N.F.2
Renier, G.3
-
44
-
-
0018218638
-
Disposition of metformin (N, N-dimethylbiguanide) in man
-
Sirtori CR, Franceschini G, Galli-Kiele M, Galli G, Bondioli A, Conti F. Disposition of metformin (N, N-dimethylbiguanide) in man. Clin. Pharmacol. Ther., 1978, 24(6), 683-193.
-
(1978)
Clin. Pharmacol. Ther.
, vol.24
, Issue.6
, pp. 683-193
-
-
Sirtori, C.R.1
Franceschini, G.2
Galli-Kiele, M.3
Galli, G.4
Bondioli, A.5
Conti, F.6
-
45
-
-
79951650552
-
-
Available from, Accessed Jan 15, 2011
-
Available from URL:http://www.sanofi-aventis.ca/products/en/glucophage. pdf (Accessed Jan 15, 2011).
-
-
-
-
46
-
-
0024382099
-
Hemodialysis in the treatment of lactic acidosis in diabetics treated by metformin: A study of metformin elimination
-
Lalau, J. D.; Andrejak, M.; Moriniere, P.; Coevoet, B.; Debussche, X.; Westeel, P. F.; Fournier, A.; Quichaud, J. Hemodialysis in the treatment of lactic acidosis in diabetics treated by metformin: a study of metformin ekimination. Int. J. Clin. Pharmacol. Ther. Toxicol, 1989, 27(6), 285-288. (Pubitemid 19147149)
-
(1989)
International Journal of Clinical Pharmacology Therapy and Toxicology
, vol.27
, Issue.6
, pp. 285-288
-
-
Lalau, J.D.1
Andrejak, M.2
Moriniere, P.3
Coevoet, B.4
Debussche, X.5
Westeel, P.F.6
Fournier, A.7
Quichaud, J.8
-
47
-
-
25644457679
-
Rosiglitazone reduces insulin requirement and C-reactive protein levels in type 2 diabetic patients receiving peritoneal dialysis
-
DOI 10.1053/j.ajkd.2005.06.020, PII S0272638605009170
-
Wong, T. Y.; Szeto, C. C.; Chow, K. M.; Leung, C. B.; Lam, C. W.; Li, P. K. Rosiglitazone reduces insulin requirement and C-reactive protein levels in type 2 diabetic patients receiving peritoneal dialysis. Am. J. Kidney Dis., 2005, 46(4), 713-719. (Pubitemid 41383950)
-
(2005)
American Journal of Kidney Diseases
, vol.46
, Issue.4
, pp. 713-719
-
-
Wong, T.Y.-H.1
Szeto, C.-C.2
Chow, K.-M.3
Leung, C.-B.4
Lam, C.W.-K.5
Li, P.K.-T.6
-
48
-
-
18644382785
-
The clinical significance of PPARy agonism
-
Campbell, I. W. The clinical significance of PPARy agonism. Curr. Mol. Med., 2005, 5(3), 349-363.
-
(2005)
Curr. Mol. Med.
, vol.5
, Issue.3
, pp. 349-363
-
-
Campbell, I.W.1
-
49
-
-
0036297423
-
Insulin resistance as an independent predictor of cardiovascular mortality in patients with end-stage renal disease
-
DOI 10.1097/01.ASN.0000019900.87535.43
-
Shinohara, K.; Shoji, T.; Emoto, M.; Tahara, H.; Koyama, H.; Ishimura, E.; Miki, T.; Tabata, T.; Nishizawa, Y. Insulin resistance as an independent predictor of cardiovascular mortality in patients with end-stage renal disease. J. Am. Soc. Nephrol., 2002, 13(7), 1894-1900. (Pubitemid 34700615)
-
(2002)
Journal of the American Society of Nephrology
, vol.13
, Issue.7
, pp. 1894-1900
-
-
Shinohara, K.1
Shoji, T.2
Emoto, M.3
Tahara, H.4
Koyama, H.5
Ishimura, E.6
Miki, T.7
Tabata, T.8
Nishizawa, Y.9
-
50
-
-
0029151209
-
Regulation of glucose transport in culture muscle cells by novel hypoglycemic agents
-
Ciaraldi, T. P.; Huber-Knudsen, K.; Hickman, M.; Olefsky, J. M. Regulation of glucose transport in culture muscle cells by novel hypoglycemic agents. Metabolism, 1995, 44(8), 976-982.
-
(1995)
Metabolism
, vol.44
, Issue.8
, pp. 976-982
-
-
Ciaraldi, T.P.1
Huber-Knudsen, K.2
Hickman, M.3
Olefsky, J.M.4
-
51
-
-
0031898610
-
PPAR-γ: Adipogenic regulator and thiazolidinedione receptor
-
DOI 10.2337/diabetes.47.4.507
-
Spiegelman, B. M. PPAR-y: adipogenic regulator and thiazolidinedione receptor. Diabetes, 1998, 47(4), 507-514. (Pubitemid 28160438)
-
(1998)
Diabetes
, vol.47
, Issue.4
, pp. 507-514
-
-
Spiegelman, B.M.1
-
52
-
-
13644263258
-
Oral antidiabetic agents: Current role in type 2 diabetes mellitus
-
DOI 10.2165/00003495-200565030-00005
-
Krentz AJ, Bailey CJ. Oral antidiabetic agents: current role in type 2 diabetes mellitus. Drugs, 2005, 65(3), 385-411. (Pubitemid 40227460)
-
(2005)
Drugs
, vol.65
, Issue.3
, pp. 385-411
-
-
Krentz, A.J.1
Bailey, C.J.2
-
53
-
-
7044271016
-
Use of insulin and oral hypoglycemic medications in patients with diabetes mellitus and advanced kidney disease
-
DOI 10.1111/j.0894-0959.2004.17346.x
-
Snyder, R. W.; Berns, J. S. Use of insulin and oral hypoglycemic medications in patients with diabetes mellitus and advanced kidney disease. Semin. Dial., 2004, 17(5), 365-370. (Pubitemid 39422090)
-
(2004)
Seminars in Dialysis
, vol.17
, Issue.5
, pp. 365-370
-
-
Snyder, R.W.1
Berns, J.S.2
-
54
-
-
0033911580
-
Absorption, disposition, and metabolism of rosiglitazone, a potent thiazolidinedione insulin sensitizer, in humans
-
Cox, P. J.; Ryan, D. A.; Hollis, F. J.; Harris, A. M.; Miller, A. K.; Vousden, M.; Cowley, H. Absorption, disposition, and metabolism of rosiglitazone, a potent thiazolidinedione insulin sensitizer, in humans. Drug Metab. Dispos., 2000, 28(7), 772-780. (Pubitemid 30470827)
-
(2000)
Drug Metabolism and Disposition
, vol.28
, Issue.7
, pp. 772-780
-
-
Cox, P.J.1
Ryan, D.A.2
Hollis, F.J.3
Harris, A.-M.4
Miller, A.K.5
Vousden, M.6
Cowley, H.7
-
56
-
-
0036630554
-
Pharmacokinetics of Rosiglitazone in patients with end-stage renal disease
-
Thompson, C. K.; Zussman, B.; Miller, A. K.; Freed, M. I. Pharmakokinetics of rosiglitazone in patients with end stage renal disease. J. Int. Med. Res., 2002, 30(4), 391-399. (Pubitemid 34993563)
-
(2002)
Journal of International Medical Research
, vol.30
, Issue.4
, pp. 391-399
-
-
Thompson-Culkin, K.1
Zussman, B.2
Miller, A.K.3
Freed, M.I.4
-
57
-
-
0038746657
-
The pharmacokinetics of pioglitazone in patients with impaired renal function
-
DOI 10.1046/j.1365-2125.2003.01785.x
-
Budde, K.; Neumayer, H. H.; Fritsche, L.; Sulowicz, W.; Stompor, T.; Eckland, D. The pharmacokinetics of pioglitazone in patients with impaired renal function. Br. J. Clin. Pharmacol. 2003, 55(4), 368-374. (Pubitemid 36535367)
-
(2003)
British Journal of Clinical Pharmacology
, vol.55
, Issue.4
, pp. 368-374
-
-
Budde, K.1
Neumayer, H.-H.2
Fritsche, L.3
Sulowicz, W.4
Stompor, T.5
Eckland, D.6
-
58
-
-
66549088735
-
Plasma concentration of pioglitazone in patients with type 2 diabetes on hemodialysis
-
Abe, M.; Kikuchi, F.; Okada, K.; Matsumoto, K. Plasma concentration of pioglitazone in patients with type 2 diabetes on hemodialysis. Therap. Apher. Dial., 2009, 13(3), 238-239.
-
(2009)
Therap. Apher. Dial.
, vol.13
, Issue.3
, pp. 238-239
-
-
Abe, M.1
Kikuchi, F.2
Okada, K.3
Matsumoto, K.4
-
59
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
-
Nissen, S. E.; Wolski, K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N. Engl. J. Med., 2007, 356(24), 2457-2471. (Pubitemid 46919772)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.24
, pp. 2457-2471
-
-
Nissen, S.E.1
Wolski, K.2
-
60
-
-
77954988618
-
Risk of acute myocardial infarction, stroke, heart failure, and death in elderly medicare patients treated with rosiglitazone or pioglitazone
-
Graham, D. J.; Hellstrom, R. O.; MaCurdy, T. E.; Ali, F.; Sholley, C.; Worrall, C.; Kelman, J. A. Risk of acute myocardial infarction, stroke, heart failure, and death in elderly medicare patients treated with rosiglitazone or pioglitazone. JAMA, 2010, 304(4), 411-418.
-
(2010)
JAMA
, vol.304
, Issue.4
, pp. 411-418
-
-
Graham, D.J.1
Hellstrom, R.O.2
MaCurdy, T.E.3
Ali, F.4
Sholley, C.5
Worrall, C.6
Kelman, J.A.7
-
61
-
-
26244453309
-
Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial in macroVascular Events): A randomised controlled trial
-
DOI 10.1016/S0140-6736(05)67528-9, PII S0140673605675289
-
Dormandy, J. A.; Charbonnel, B.; Eckland, D. J.; Erdmann, E.; Massi-Benedetti, M.; Moules, I. K.; Skene, A. M.; Tan, M. H.; Lefèbvre, P. J.; Murray, G. D.; Standl, E.; Wilcox, R. G.; Wilhelmsen, L.; Betteridge, J.; Birkeland, K.; Golay, A.; Heine, R. J.; Korányi, L.; Laakso, M.; Mokán, M.; Norkus, A.; Pirags, V.; Podar, T.; Scheen, A.; Scherbaum, W.; Schernthaner, G.; Schmitz, O.; Skrha, J.; Smith, U.; Taton, J. PROactive investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (Prospective pioglitazone clinical trial in macrovascular events): a randomized controlled trial. Lancet, 2005, 366(9493), 1279-1289. (Pubitemid 41416583)
-
(2005)
Lancet
, vol.366
, Issue.9493
, pp. 1279-1289
-
-
Dormandy, J.A.1
Charbonnel, B.2
Eckland, D.J.3
Erdmann, E.4
Massi-Benedetti, M.5
Moules, I.K.6
Skene, A.M.7
Tan, M.H.8
Lefebvre, P.J.9
Murray, G.D.10
Standl, E.11
Wilcox, R.G.12
Wilhelmsen, L.13
Betteridge, J.14
Birkeland, K.15
Golay, A.16
Heine, R.J.17
Koranyi, L.18
Laakso, M.19
Mokan, M.20
Norkus, A.21
Pirags, V.22
Podar, T.23
Scheen, A.24
Scherbaum, W.25
Schernthaner, G.26
Schmitz, O.27
Skrha, J.28
Smith, U.29
Taton, J.30
more..
-
62
-
-
0036076907
-
Metabolic and additional vascular effects of thiazolidinediones
-
Martens, F. M.; Visseren, F. L.; Lemay, J.; de Koning, E. J.; Rabelink, T. J. Metabolic and additional vascular effects of thiazolidinediones. Drugs, 2002, 62(10), 1463-1480. (Pubitemid 34804155)
-
(2002)
Drugs
, vol.62
, Issue.10
, pp. 1463-1480
-
-
Martens, F.M.A.C.1
Visseren, F.L.J.2
Lemay, J.3
De Koning, E.J.P.4
Rabelink, T.J.5
-
63
-
-
0141620204
-
Rosiglitazone improves glucose metabolism in nondiabetic uremic patients on CAPD
-
Lin, S. H.; Lin, Y. F.; Kuo, S. W.; Hsu, Y. J.; Hung, Y. J. Rosiglitazone improves glucose metabolism in nondiabetic uremic patients on CAPD. Am. J. Kid. Dis., 2003, 42(4), 774-780.
-
(2003)
Am. J. Kid. Dis.
, vol.42
, Issue.4
, pp. 774-780
-
-
Lin, S.H.1
Lin, Y.F.2
Kuo, S.W.3
Hsu, Y.J.4
Hung, Y.J.5
-
64
-
-
33746371464
-
Protection of the kidney by thiazolidinediones: An assessment from bench to bedside
-
DOI 10.1038/sj.ki.5001620, PII 5001620
-
Sarafidis, P. A.; Bakris, G. L. Protection of the kidney by thiazolidinediones: An assessment from bench to bedside. Kidney Int., 2006, 70(7), 1223-1233. (Pubitemid 44435173)
-
(2006)
Kidney International
, vol.70
, Issue.7
, pp. 1223-1233
-
-
Sarafidis, P.A.1
Bakris, G.L.2
-
65
-
-
33744534329
-
Peroxisome proliferator-activated receptor gamma agonists in renal disease
-
DOI 10.1530/eje.1.02134
-
Iglesias, P.; Díez, J. J. Peroxisome proliferator-activated receptor gamma agonists in renal disease. Eur. J. Endocrinol., 2006, 154(5), 613-621. (Pubitemid 43810845)
-
(2006)
European Journal of Endocrinology
, vol.154
, Issue.5
, pp. 613-621
-
-
Iglesias, P.1
Diez, J.J.2
-
66
-
-
0344233280
-
Effects of Rosiglitazone Maleate When Added to a Sulfonylurea Regimen in Patients with Type 2 Diabetes Mellitus and Mild to Moderate Renal Impairment: A Post Hoc Analysis
-
DOI 10.1016/S0149-2918(03)80331-4
-
Agrawal, A.; Sautter, M. C.; Jones, N. P. Effects of rosiglitazone maleate when added to a sulfonylurea regimen in type 2 diabetics mellitus and mild to moderate renal impairment: a post hoc analysis. Clin. Ther., 2003, 25(11), 2754-2764. (Pubitemid 37510588)
-
(2003)
Clinical Therapeutics
, vol.25
, Issue.11
, pp. 2754-2764
-
-
Agrawal, A.1
Sautter, M.C.2
Jones, N.P.3
-
67
-
-
0026021161
-
Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
-
Defronzo, R. A.; Ferrannini, E. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care, 1991, 14(3), 173-194.
-
(1991)
Diabetes Care
, vol.14
, Issue.3
, pp. 173-194
-
-
Defronzo, R.A.1
Ferrannini, E.2
-
68
-
-
84910011021
-
A review of metabolic and cardiovascular effects of oral antidiabetic agents: Beyond glucose-level lowering
-
Ginsberg, H.; Plutzky, J.; Sobel, B. E. A review of metabolic and cardiovascular effects of oral antidiabetic agents: beyond glucoselevel lowering. J. Cardiovasc. Risk., 1999, 6(5), 337-346. (Pubitemid 30025631)
-
(1999)
Journal of Cardiovascular Risk
, vol.6
, Issue.5
, pp. 337-346
-
-
Ginsberg, H.1
Plutzky, J.2
Sobel, B.E.3
-
69
-
-
33846003119
-
Rosiglitazone in diabetes control in hemodialysis patients with and without viral hepatitis infection
-
Chiang, C. K.; Ho, T. I.; Peng, Y. S.; Hsu, S. P.; Pai, M. F.; Yang, S. Y.; Hung, K. Y.; Wu, K. D. Rosiglitazone in diabetes control in hemodialysis patients with and without viral hepatitis infection. Diabetes Care, 2007, 30(1), 3-7.
-
(2007)
Diabetes Care
, vol.30
, Issue.1
, pp. 3-7
-
-
Chiang, C.K.1
Ho, T.I.2
Peng, Y.S.3
Hsu, S.P.4
Pai, M.F.5
Yang, S.Y.6
Hung, K.Y.7
Wu, K.D.8
-
70
-
-
77953634420
-
Clinical effectiveness and safety evaluation of longterm pioglitazone treatment for erythropoietin responsiveness and insulin resistance in type 2 diabetic patients on hemodialysis
-
Abe, M.; Okada, K.; Maruyama, T.; Maruyama, N.; Soma, M.; Matsumoto, K. Clinical effectiveness and safety evaluation of longterm pioglitazone treatment for erythropoietin responsiveness and insulin resistance in type 2 diabetic patients on hemodialysis. Expert Opin. Pharmacother., 2010, 11(10), 1611-1620.
-
(2010)
Expert Opin. Pharmacother.
, vol.11
, Issue.10
, pp. 1611-1620
-
-
Abe, M.1
Okada, K.2
Maruyama, T.3
Maruyama, N.4
Soma, M.5
Matsumoto, K.6
-
71
-
-
0037705723
-
Thiazolidinedione safety and efficacy in ambulatory patients receiving hemodialysis
-
DOI 10.1592/phco.23.7.861.32727
-
Manley, H. J.; Allcock, N. M. Thiazolidinedione safety and efficacy in ambulatory patients receiving hemodialysis. Pharmacotherapy, 2003, 23(7), 861-865. (Pubitemid 36875669)
-
(2003)
Pharmacotherapy
, vol.23
, Issue.7
, pp. 861-865
-
-
Manley, H.J.1
Allcock, N.M.2
-
72
-
-
0035146515
-
Once- and twice-daily dosing with rosiglitazone improves glycemic control in patients with type 2 diabetes
-
Phillips, L. S.; Grunberger, G.; Miller, E.; Patwardhan, R.; Rappaport, E.; Salzman, A. Once-and twice-daily dosing with rosiglitazone improves glycemic control in patients with type 2 diabetes. Diabetes Care, 2001, 24(2), 308-315. (Pubitemid 32119130)
-
(2001)
Diabetes Care
, vol.24
, Issue.2
, pp. 308-315
-
-
Phillips, L.S.1
Grunberger, G.2
Miller, E.3
Patwardhan, R.4
Rappaport, E.B.5
Salzman, A.6
-
73
-
-
0033754530
-
Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes
-
Aronoff, S.; Rosenblatt, S.; Braithwaite, S.; Egen, J. W.; Mathisen, A. L.; Schneider, R. L. Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes. Diabetes Care, 2000, 23(11), 1605-1611.
-
(2000)
Diabetes Care
, vol.23
, Issue.11
, pp. 1605-1611
-
-
Aronoff, S.1
Rosenblatt, S.2
Braithwaite, S.3
Egen, J.W.4
Mathisen, A.L.5
Schneider, R.L.6
-
74
-
-
0344304678
-
Thiazolidinedione Use, Fluid Retention, and Congestive Heart Failure: A Consensus Statement from the American Heart Association and American Diabetes Association
-
DOI 10.1161/01.CIR.0000103683.99399.7E
-
Nesto, R. W.; Bell, D.; Bonow, R. Q.; Fonseca, V.; Grandy, S. M.; Horton, E. S.; Le Winter, M.; Porte, D.; Semenkovich, C. F.; Smith, S.; Young, L. H.; Kahn, R. Thiazolidinedione use, fluid retention and congestive heart failure. A consensus statement from the AHA and ADA. Circulation, 2003, 108(23), 2941-2948. (Pubitemid 37517824)
-
(2003)
Circulation
, vol.108
, Issue.23
, pp. 2941-2948
-
-
Nesto, R.W.1
Bell, D.2
Bonow, R.O.3
Fonseca, V.4
Grundy, S.M.5
Horton, E.S.6
Le Winter, M.7
Porte, D.8
Semenkovich, C.F.9
Smith, S.10
Young, L.H.11
Kahn, R.12
-
75
-
-
52149083499
-
Clinical investigation of the effects of pioglitazone on the improvement of insulin resistance and blood pressure in type 2-diabetic patients undergoing hemodialysis
-
Abe, M.; Okada, K.; Kikuchi, F.; Matsumoto, K. Clinical investigation of the effects of pioglitazone on the improvement of insulin resistance and blood pressure in type 2-diabetic patients undergoing hemodialysis. Clin. Nephrol., 2008, 70(3), 220-228.
-
(2008)
Clin. Nephrol.
, vol.70
, Issue.3
, pp. 220-228
-
-
Abe, M.1
Okada, K.2
Kikuchi, F.3
Matsumoto, K.4
-
76
-
-
0038220757
-
Rosiglitazone improves insulin sensitivity and lowers blood pressure in hypertensive patients
-
DOI 10.2337/diacare.26.1.172
-
Raji, A.; Seely, E. W.; Bekins, S. A.; Williams, G. H.; Simonson, D. C. Rosiglitazone improves insulin sensitivity and lowers blood pressure in hypertensive patients. Diabetes Care, 2003, 26(1), 172-178. (Pubitemid 36929012)
-
(2003)
Diabetes Care
, vol.26
, Issue.1
, pp. 172-178
-
-
Raji, A.1
Seely, E.W.2
Bekins, S.A.3
Williams, G.H.4
Simonson, D.C.5
-
77
-
-
33846006173
-
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
-
DOI 10.1016/S0140-6736(06)69705-5, PII S0140673606697055
-
Drucker, D. J.; Nauck, M. A. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet, 2006, 368(9548), 1696-1705. (Pubitemid 46048557)
-
(2006)
Lancet
, vol.368
, Issue.9548
, pp. 1696-1705
-
-
Drucker, D.J.1
Nauck, M.A.2
-
78
-
-
33846844912
-
Dipeptidyl peptidase-IV inhibitors: A major new class of oral antidiabetic drug
-
DOI 10.1111/j.1463-1326.2007.00705.x, Future Treatments: A Focus on Dipeptidyl Peptidase-IV Inhibitors
-
Idris, I.; Donnelly, R. Dipeptidyl peptidase-IV inhibitors: a major new class of oral antidiabetic drug. Diabetes. Obes. Metab., 2007, 9(2), 153-165. (Pubitemid 46206559)
-
(2007)
Diabetes, Obesity and Metabolism
, vol.9
, Issue.2
, pp. 153-165
-
-
Idris, I.1
Donnelly, R.2
-
79
-
-
44949231427
-
Dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes mellitus
-
Richter, B.; Banderia-Echtler, E.; Bergerhoff, K.; Lerch. C. L. Dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes mellitus. Cochrane. Database. Syst. Rev., 2008, 16(2), CD006739.
-
(2008)
Cochrane. Database. Syst. Rev.
, vol.16
, Issue.2
-
-
Richter, B.1
Banderia-Echtler, E.2
Bergerhoff, K.3
Lerch, C.L.4
-
80
-
-
77955456705
-
Pharmacokinetics of dipeptidylpeptidase-4 inhibitors
-
Scheen, A. J. Pharmacokinetics of dipeptidylpeptidase-4 inhibitors. Diabetes Obes. Metab., 2010, 12(8), 648-658.
-
(2010)
Diabetes Obes. Metab.
, vol.12
, Issue.8
, pp. 648-658
-
-
Scheen, A.J.1
-
81
-
-
34247269160
-
Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: Focus on sitagliptin
-
DOI 10.1038/sj.clpt.6100167, PII 6100167
-
Herman, G. A.; Stein, P. P.; Thornberry, N. A.; Wagner, J. A. Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: focus on sitagliptin. Clin. Pharmacol. Ther., 2007, 81(5), 761-767. (Pubitemid 46625120)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.81
, Issue.5
, pp. 761-767
-
-
Herman, G.A.1
Stein, P.P.2
Thornberry, N.A.3
Wagner, J.A.4
-
82
-
-
33644618433
-
The biology of incretin hormones
-
Drucker, D. J. The biology of incretin hormones. Cell Metab., 2006, 3(3), 153-165.
-
(2006)
Cell. Metab.
, vol.3
, Issue.3
, pp. 153-165
-
-
Drucker, D.J.1
-
83
-
-
34047097841
-
14C]sitagliptin in humans
-
DOI 10.1124/dmd.106.013136
-
Vincent, S. H.; Reed, J. R.; Bergman, A. J.; Elmore, C. S.; Zhu, B.; Xu, S.; Ebel, D.; Larson, P.; Zeng, W.; Chen, L.; Dilzer, S.; Lasseter, K.; Gottesdiener, K.; Wagner, J. A.; Herman, G. A. Metabolism and Excretion of the dipeptidyl peptidase 4 inhibitor [14C]Sitagliptin in humans. Drug Metab. Dispos., 2007, 35(4), 533-538. (Pubitemid 46513255)
-
(2007)
Drug Metabolism and Disposition
, vol.35
, Issue.4
, pp. 533-538
-
-
Vincent, S.H.1
Reed, J.R.2
Bergman, A.J.3
Elmore, C.S.4
Zhu, B.5
Xu, S.6
Ebel, D.7
Larson, P.8
Zeng, W.9
Chen, L.10
Dilzer, S.11
Lasseter, K.12
Gottesdiener, K.13
Wagner, J.A.14
Herman, G.A.15
-
84
-
-
33749871472
-
Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes
-
DOI 10.1210/jc.2006-1009
-
Herman, G. A.; Bergman, A.; Stevens, C.; Kotey, P.; Yi, B.; Zhao, P.; Dietrich, B.; Golor, G.; Schrodter, A.; Keymeulen, B.; Lasseter, K. C.; Kipnes, M. S.; Snyder, K.; Hilliard, D.; Tanen, M.; Cilissen, C.; De Smet, M.; de Lepeleire, I.; Van Dyck, K.; Wang, A. Q.; Zeng, W.; Davies, M. J.; Tanaka, W.; Holst, J. J.; Deacon, C. F.; Gottesdiener, K. M.; Wagner, J. A. Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels following an oral glucose tolerance test in patients with type 2 diabetes. J. Clin. Endocrinol. Metab., 2006, 91(11), 4612-4619. (Pubitemid 44833446)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.11
, pp. 4612-4619
-
-
Herman, G.A.1
Bergman, A.2
Stevens, C.3
Kotey, P.4
Yi, B.5
Zhao, P.6
Dietrich, B.7
Golor, G.8
Schrodter, A.9
Keymeulen, B.10
Lasseter, K.C.11
Kipnes, M.S.12
Snyder, K.13
Hilliard, D.14
Tanen, M.15
Cilissen, C.16
De Smet, M.17
De Lepeleire, I.18
Van Dyck, K.19
Wang, A.Q.20
Zeng, W.21
Davies, M.J.22
Tanaka, W.23
Holst, J.J.24
Deacon, C.F.25
Gottesdiener, K.M.26
Wagner, J.A.27
more..
-
85
-
-
28844482322
-
Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: Results from two randomized, double-blind, placebo-controlled studies with single oral doses
-
DOI 10.1016/j.clpt.2005.09.002, PII S0009923605004108
-
Herman, G. A.; Stevens, C.; Van Dyck, K.; Bergman, A.; Yi, B.; De Smet, M.; Snyder, K.; Hilliard, D.; Tanen, M.; Tanaka, W.; Wang, A. Q.; Zeng, W., Musson, D.; Winchell, G.; Davies, M. J.; Ramael, S.; Gottesdiener, K. M., Wagner, J. A. Pharmacokinetics and pharmacodynamics of single doses of sitagliptin, an inhibitor of dipeptidyl peptidase-IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral doses. Clin. Pharmacol Ther., 2005, 78(6), 675-688. (Pubitemid 41773643)
-
(2005)
Clinical Pharmacology and Therapeutics
, vol.78
, Issue.6
, pp. 675-688
-
-
Herman, G.A.1
Stevens, C.2
Van Dyck, K.3
Bergman, A.4
Yi, B.5
De Smet, M.6
Snyder, K.7
Hilliard, D.8
Tanen, M.9
Tanaka, W.10
Wang, A.Q.11
Zeng, W.12
Musson, D.13
Winchell, G.14
Davies, M.J.15
Ramael, S.16
Gottesdiener, K.M.17
Wagner, J.A.18
-
86
-
-
34247236764
-
Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein
-
DOI 10.1124/jpet.106.116517
-
Chu, X. Y.; Bleasby, K.; Yabut, J.; Cai, X.; Chan, G. H.; Hafey, M. J.; Xu, S.; Bergman, A. J.; Braun, M. P.; Dean, D. C.; Evers, R. Transport of the dipeptidyl peptidase-4 inhibtor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein. J. Pharmacol. Exp. Ther., 2007, 321(2), 673-683. (Pubitemid 46624514)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.321
, Issue.2
, pp. 673-683
-
-
Chu, X.-Y.1
Bleasby, K.2
Yabut, J.3
Cai, X.4
Chan, G.H.5
Hafey, M.J.6
Xu, S.7
Bergman, A.J.8
Braun, M.P.9
Dean, D.C.10
Evers, R.11
-
87
-
-
34447120048
-
Effect of renal insufficiency on the pharmacokinetics of sitagliptin, a dipeptidyl peptidase-4 inhibitor
-
DOI 10.2337/dc06-2545
-
Bergman, A. J.; Cote, J.; Yi, B.; Marbuy, T.; Swan, S. K.; Smith, W.; Gottesdiener, K.; Wagner, J.; Herman, G. A. Effect of renal insufficiency on the pharmacokinetics of sitagliptin, a dipeptidyl peptidase-4 inhibitor. Diabetes Care, 2007, 30(7), 1862-1864. (Pubitemid 47036366)
-
(2007)
Diabetes Care
, vol.30
, Issue.7
, pp. 1862-1864
-
-
Bergman, A.J.1
Cote, J.2
Yi, B.3
Marbury, T.4
Swan, S.K.5
Smith, W.6
Gottesdiener, K.7
Wagner, J.8
Herman, G.A.9
-
88
-
-
45449105789
-
Safety and efficacy of sitagliptin in patients with type 2 diabetes and chronic renal insufficiency
-
DOI 10.1111/j.1463-1326.2008.00914.x
-
Chan, J. C.; Scott, R.; Arjona Ferreira, J. C.; Sheng, D.; Gonzalez, E.; Davies, M. J.; Stein, P. P.; Kaufman, K. D.; Amatruda, J. M.; Williams-Hermann, D. Safety and efficacy of sitagliptin in patients with type 2 diabetes and chronic renal insufficiency. Diabetes Obes. Metab., 2008, 10(7), 545-555. (Pubitemid 351850898)
-
(2008)
Diabetes, Obesity and Metabolism
, vol.10
, Issue.7
, pp. 545-555
-
-
Chan, J.C.N.1
Scott, R.2
Arjona Ferreira, J.C.3
Sheng, D.4
Gonzalez, E.5
Davies, M.J.6
Stein, P.P.7
Kaufman, K.D.8
Amatruda, J.M.9
Williams-Herman, D.10
-
89
-
-
33751098267
-
Vildagliptin
-
DOI 10.2165/00003495-200666150-00007
-
Henness, S.; Keam, S. J. Vildagliptin. Drugs, 2006, 66(15), 1989-2001. (Pubitemid 44771935)
-
(2006)
Drugs
, vol.66
, Issue.15
, pp. 1989-2001
-
-
Henness, S.1
Keam, S.J.2
-
90
-
-
55049090992
-
Vildagliptin: A review of its use in the management of type 2 diabetes mellitus
-
Croxtall, J. D.; Keam, S. J. Vildagliptin: a review of its use in the management of type 2 diabetes mellitus. Drugs, 2008, 68(16), 2387-2409.
-
(2008)
Drugs
, vol.68
, Issue.16
, pp. 2387-2409
-
-
Croxtall, J.D.1
Keam, S.J.2
-
91
-
-
34347393269
-
Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus
-
DOI 10.2165/00003088-200746070-00003
-
He, Y. L.; Serra, D.; Wang, Y.; Campestrini, J.; Riviere, G. J.; Deacon, C. F.; Holst, J. J.; Schwartz, H. S.; Nielsen, J. C.; Ligueros-Saylan, M. Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus. Clin. Pharmacokinet., 2007, 46(7), 577-588. (Pubitemid 47025358)
-
(2007)
Clinical Pharmacokinetics
, vol.46
, Issue.7
, pp. 577-588
-
-
He, Y.-L.1
Serra, D.2
Wang, Y.3
Campestrini, J.4
Riviere, G.-J.5
Deacon, C.F.6
Holst, J.J.7
Schwartz, S.8
Nielsen, J.C.9
Ligueros-Saylan, M.10
-
92
-
-
61449170189
-
Absorption, metabolism, and excretion of [14C]Vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in humans
-
He, H.; Yin, T. H.; Smith, H.; Batard, Y.; Wang, L.; Einolf, H.; Gu, H.; Mangold, J. B.; Fischer, V.; Howard, D. Absorption, metabolism, and excretion of [14C]Vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in humans. Drug Metab. Dispos., 2009, 37(3), 536-544.
-
(2009)
Drug Metab. Dispos.
, vol.37
, Issue.3
, pp. 536-544
-
-
He, H.1
Yin, T.H.2
Smith, H.3
Batard, Y.4
Wang, L.5
Einolf, H.6
Gu, H.7
Mangold, J.B.8
Fischer, V.9
Howard, D.10
-
93
-
-
41649102998
-
Pharmacokinetics, pharmacodynamics, and tolerability of single increasing doses of the dipeptidyl peptidase-4 inhibitor alogliptin in healthy male subjects
-
DOI 10.1016/j.clinthera.2008.03.005, PII S0149291808001185
-
Christopher, R.; Covington, P.; Davenport, M.; Fleck, P.; Mekki, Q. A.; Wann, E. R.; Karim, A. Pharmacokinetics, pharmacodynamics, and tolerability of single increasing doses of the dipeptidyl peptidase-4 inhibitor alogliptin in healthy male subjects. Clin. Ther., 2008, 30(3), 513-527. (Pubitemid 351492530)
-
(2008)
Clinical Therapeutics
, vol.30
, Issue.3
, pp. 513-527
-
-
Christopher, R.1
Covington, P.2
Davenport, M.3
Fleck, P.4
Mekki, Q.A.5
Wann, E.R.6
Karim, A.7
-
94
-
-
73649128872
-
Pharmacokinetic of alogliptin when administered with food, metformin, or cimetidine: A two-phase, crossover study in healthy subjects
-
Karim, A.; Covington, P.; Christopher, R.; Davenport, M.; Fleck, P.; Li, X.; Wann, E.; Mekki, Q. Pharmacokinetic of alogliptin when administered with food, metformin, or cimetidine: a two-phase, crossover study in healthy subjects. Int. J. Clin. Pharmacol. Ther., 2010, 48(1), 46-58.
-
(2010)
Int. J. Clin. Pharmacol. Ther.
, vol.48
, Issue.1
, pp. 46-58
-
-
Karim, A.1
Covington, P.2
Christopher, R.3
Davenport, M.4
Fleck, P.5
Li, X.6
Wann, E.7
Mekki, Q.8
-
95
-
-
65649116135
-
Alogliptin: A new. highly selective dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
-
Partley, R. E. Alogliptin: a new. highly selective dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes. Expert Opin. Pharmacother., 2009, 10, 503-512.
-
(2009)
Expert Opin. Pharmacother.
, vol.10
, pp. 503-512
-
-
Partley, R.E.1
-
96
-
-
66649119188
-
Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections
-
Fura, A.; Khanna, A.; Vyas, V.; Koplowitz, B.; Chang, S. Y.; Caporuscio, C.; Boulton, D. W.; Christopher, L. J.; Chadwick, K. D. Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections. Drug Metab. Dispos., 2009;37(6):1164-1171.
-
(2009)
Drug Metab. Dispos.
, vol.37
, Issue.6
, pp. 1164-1171
-
-
Fura, A.1
Khanna, A.2
Vyas, V.3
Koplowitz, B.4
Chang, S.Y.5
Caporuscio, C.6
Boulton, D.W.7
Christopher, L.J.8
Chadwick, K.D.9
-
97
-
-
79951622930
-
-
Available from, Accessed Jan 15, 2011
-
Available from URL:http://www.ema.europa.eu/humandocs/PDFs/EPAR/onglyza/ H-1039-fr1.pdf (Accessed Jan 15, 2011).
-
-
-
-
98
-
-
58149247983
-
Concentrationdependent plasma protein binding of the novel dipeptidyl peptidase 4 inhibitor BI 1356 due to saturable binding to its target in plasma of mice, rats and humans
-
Fuchs, H.; Tillement, J. P.; Urien, S.; Greischel, A.; Roth, W. Concentrationdependent plasma protein binding of the novel dipeptidyl peptidase 4 inhibitor BI 1356 due to saturable binding to its target in plasma of mice, rats and humans. J. Pharm. Pharmacol., 2009, 61(1), 55-62.
-
(2009)
J. Pharm. Pharmacol.
, vol.61
, Issue.1
, pp. 55-62
-
-
Fuchs, H.1
Tillement, J.P.2
Urien, S.3
Greischel, A.4
Roth, W.5
-
99
-
-
70349733673
-
Tissue distribution of the novel DPP-4 inhibitor BI 1356 is dominated by saturable binding to its target in rats
-
Fuchs, H.; Binder, R.; Greischel, A. Tissue distribution of the novel DPP-4 inhibitor BI 1356 is dominated by saturable binding to its target in rats. Biopharm. Drug Dispos., 2009, 30, 229-240.
-
(2009)
Biopharm. Drug Dispos.
, vol.30
, pp. 229-240
-
-
Fuchs, H.1
Binder, R.2
Greischel, A.3
-
100
-
-
77950197593
-
The metabolism and disposition of the oral dipeptidyl peptidase-4 inhibitor, linagliptin, in humans
-
Blech, S.; Ludwig-Schwellinger, E.; Graefe-Mody, E. U.; Withopf, B.; Wagner, K. The metabolism and disposition of the oral dipeptidyl peptidase-4 inhibitor, linagliptin, in humans. Drug Metab. Dispos., 2010, 38(4), 667-678.
-
(2010)
Drug Metab. Dispos.
, vol.38
, Issue.4
, pp. 667-678
-
-
Blech, S.1
Ludwig-Schwellinger, E.2
Graefe-Mody, E.U.3
Withopf, B.4
Wagner, K.5
-
101
-
-
51849103389
-
Safety, tolerability, pharmacokinetics and pharmacodynamics of single oral doses of Bl 1356, an inhibitor of dipeptidylpeptidase 4, in healthy male volunteers
-
Huttner, S.; Graefe-Mody, E. U.; Withopf, B.; Ring, A.; Dugi, K. A. Safety, tolerability, pharmacokinetics and pharmacodynamics of single oral doses of Bl 1356, an inhibitor of dipeptidylpeptidase 4, in healthy male volunteers. J. Clin. Pharmacol., 2008, 48(10), 1171-1178.
-
(2008)
J. Clin. Pharmacol.
, vol.48
, Issue.10
, pp. 1171-1178
-
-
Huttner, S.1
Graefe-Mody, E.U.2
Withopf, B.3
Ring, A.4
Dugi, K.A.5
-
102
-
-
0030901415
-
Enteroglucagon
-
DOI 10.1146/annurev.physiol.59.1.257
-
Holst, J. J. Enteroglucagon. Ann. Rev. Physiol., 1997, 59, 257-271. (Pubitemid 27142442)
-
(1997)
Annual Review of Physiology
, vol.59
, pp. 257-271
-
-
Holst, J.J.1
-
103
-
-
0037256214
-
Glucagon-like peptide 1 and gastric inhibitory polypeptide: Potential applications in type 2 diabetes mellitus
-
DOI 10.2165/00063030-200317020-00002
-
Meier, J. J.; Gallwitz, B.; Nauck, M. A. Glucagon-like peptide and gastric inhibitory polypeptide: potential applications in type 2 dibetes mellitus. Bio. Drugs, 2003, 17(2), 93-102. (Pubitemid 36433991)
-
(2003)
BioDrugs
, vol.17
, Issue.2
, pp. 93-102
-
-
Meier, J.J.1
Gallwitz, B.2
Nauck, M.A.3
-
104
-
-
0344549608
-
Incretins and Their Analogues as New Antidiabetic Drugs
-
DOI 10.1358/dnp.2003.16.7.829353
-
Nauck, M. A.; Meier, J. J.; Creutzfeldt, W. Incretins and their analogues as new antidiabetic agents. Drug News Perspect., 2003, 16(7), 413-422. (Pubitemid 37448511)
-
(2003)
Drug News and Perspectives
, vol.16
, Issue.7
, pp. 413-422
-
-
Nauck, M.A.1
Meier, J.J.2
Creutzfeldt, W.3
-
105
-
-
33750288460
-
Five weeks of treatment with the GLP-1 analogue liraglutide improves glycaemic control and lowers body weight in subjects with type 2 diabetes
-
DOI 10.1055/s-2006-924230
-
Nauck, M. A.; Hompesch, M.; Filipczak, R.; Le, T. D. T.; Zdravkovic, M.; Gumprecht, J. Five weeks of treatment with GLP-1 analogue liraglutide improves glycemic control and lowers body weight in subjects with type 2 diabetes. Exp. Clin. Endocrinol. Diabetes., 2006, 114(8), 417-423. (Pubitemid 44620484)
-
(2006)
Experimental and Clinical Endocrinology and Diabetes
, vol.114
, Issue.8
, pp. 417-423
-
-
Nauck, M.A.1
Hompesch, M.2
Filipczak, R.3
Le, T.D.T.4
Zdravkovic, M.5
Gumprecht, J.6
-
106
-
-
34248223285
-
Biology of Incretins: GLP-1 and GIP
-
DOI 10.1053/j.gastro.2007.03.054, PII S001650850700580X
-
Baggio, L. L.; Drucker, D. J. Biology of incretins: GLP-1 and GIP. Gastroenterology, 2007, 132(6), 2131-2157. (Pubitemid 46711096)
-
(2007)
Gastroenterology
, vol.132
, Issue.6
, pp. 2131-2157
-
-
Baggio, L.L.1
Drucker, D.J.2
-
107
-
-
33646497453
-
Investigation of exenatide elimination and its in vivo and in vitro degradation
-
Copley, K.; McCowen, K.; Hiles, R.; Nielsen, L. L.; Young, A.; Parkes, D. G. Investigation of exenatide elimination and its in vivo and in vitro degradation. Curr. Drug. Metab., 2006, 7(4), 367-374.
-
(2006)
Curr. Drug. Metab.
, vol.7
, Issue.4
, pp. 367-374
-
-
Copley, K.1
McCowen, K.2
Hiles, R.3
Nielsen, L.L.4
Young, A.5
Parkes, D.G.6
-
108
-
-
34548034895
-
Effect of renal impairment on the pharmacokinetics of exenatide
-
DOI 10.1111/j.1365-2125.2007.02890.x
-
Linnebjerg, H.; Kothare, P. A.; Park, S.; Mace, K.; Reddy, S.; Mitchell, M.; Lins, R. Effect of renal impairment on the pharmacokinetics of exenatide. Br. J. Clin. Pharmacol., 2007, 64(3), 317-327. (Pubitemid 47283860)
-
(2007)
British Journal of Clinical Pharmacology
, vol.64
, Issue.3
, pp. 317-327
-
-
Linnebjerg, H.1
Kothare, P.A.2
Park, S.3
Mace, K.4
Reddy, S.5
Mitchell, M.6
Lins, R.7
-
110
-
-
0034108646
-
Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
-
DOI 10.1021/jm9909645
-
Knudsen, L. B.; Nielsen, P. F.; Huusfeldt, P. O.; Johansen, N. L.; Madsen, K.; Pedersen, F. Z.; Thogersen, H.; Wilken, M.; Agerso, H. Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration. J. Med. Chem., 2000, 43(9), 1664-1669. (Pubitemid 30304999)
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, Issue.9
, pp. 1664-1669
-
-
Knudsen, L.B.1
Nielsen, P.F.2
Huusfeldt, P.O.3
Johansen, N.L.4
Madsen, K.5
Pedersen, F.Z.6
Thogersen, H.7
Wilken, M.8
Agerso, H.9
-
111
-
-
0036189831
-
The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men
-
DOI 10.1007/s00125-001-0719-z
-
Agerso, H.; Jensen, L. B.; Elbrond, B.; Rolan, P.; Zdravkovic, M. The pharmacokinetics, pharmacodinamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men. Diabetologia, 2002, 45(2), 195-202. (Pubitemid 34208381)
-
(2002)
Diabetologia
, vol.45
, Issue.2
, pp. 195-202
-
-
Agerso, H.1
Jensen, L.B.2
Elbrond, B.3
Rolan, P.4
Zdravkovic, M.5
-
112
-
-
78049365082
-
Metabolism and excretion of the once daily human GLP-1 analog liraglutide in healthy males subjects and its in vitro degradation by dipeptidyl peptidase IV and neutral endopeptidase
-
Malm-Erjefalt, M.; Bjornsdottir, I.; Vanggaard J.; Helleberg, H.; Larsen, U.; Oosterhuis, B.; van Lier, J. J.; Zdravkovic, M. Olsen, A. K. Metabolism and excretion of the once daily human GLP-1 analog liraglutide in healthy males subjects and its in vitro degradation by dipeptidyl peptidase IV and neutral endopeptidase. Drug Metab. Dispos., 2010, 38(11), 1944-1953.
-
(2010)
Drug Metab. Dispos.
, vol.38
, Issue.11
, pp. 1944-1953
-
-
Malm-Erjefalt, M.1
Bjornsdottir, I.2
Vanggaard, J.3
Helleberg, H.4
Larsen, U.5
Oosterhuis, B.6
Van Lier, J.J.7
Zdravkovic, M.8
Olsen, A.K.9
-
113
-
-
0036066641
-
Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes
-
Juhl, C. B.; Hollingdal, M.; Sturis, J.; Jakobsen, G.; Agerso, H.; Veldhuis, J.; Porksen, N.; Schmitz, O. Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes. Diabetes, 2002, 51(2), 424-429. (Pubitemid 34764798)
-
(2002)
Diabetes
, vol.51
, Issue.2
, pp. 424-429
-
-
Juhl, C.B.1
Hollingdal, M.2
Sturis, J.3
Jakobsen, G.4
Agerso, H.5
Veldhuis, J.6
Porksen, N.7
Schmitz, O.8
-
114
-
-
0038353630
-
The GLP-1 derivative NN2211 restores β-cell sensitivity to glucose in type 2 diabetic patients after a single dose
-
Chang, A. M.; Jakobsen, G.; Sturis, J.; Smith, M. J.; Bloem, C. I.; Galecki, A.; Halter, J. B. The GLP-1 derivative NN2211 restores beta-cell sensitivity to glucose in type 2 diabetic patients after a single dose. Diabetes, 2003, 52(7), 1786-1791. (Pubitemid 36792471)
-
(2003)
Diabetes
, vol.52
, Issue.7
, pp. 1786-1791
-
-
Chang, A.M.1
Jakobsen, G.2
Sturis, J.3
Smith, M.J.4
Bloem, C.J.5
An, B.6
Galecki, A.7
Halter, J.B.8
-
115
-
-
2342599057
-
One Week's Treatment with the Long-Acting Glucagon-Like Peptide 1 Derivative Liraglutide (NN2211) Markedly Improves 24-h Glycemia and α- and β-Cell Function and Reduces Endogenous Glucose Release in Patients with Type 2 Diabetes
-
DOI 10.2337/diabetes.53.5.1187
-
Degn, K. B.; Juhl, C. B.; Sturis, J.; Jakobsen, G.; Brock, B.; Chandramouli, V.; Rungby, J.; Landau, B. R.; Schmitz, O. One week's treatment with the long-acting GLP-1 derivative, liraglutide (NN2211), markedly improves 24-h glycaemia, alpha-and betacell function and reduces endogenous glucose release in patients with type 2 diabetes. Diabetes, 2004, 53(5), 1187-1194. (Pubitemid 38569002)
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1187-1194
-
-
Degn, K.B.1
Juhl, C.B.2
Sturis, J.3
Jakobsen, G.4
Brock, B.5
Chandramouli, V.6
Rungby, J.7
Landau, B.R.8
Schmitz, O.9
-
116
-
-
39749143348
-
Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus
-
DOI 10.1111/j.1464-5491.2007.02333.x
-
Vilsboll, T.; Brock, B.; Perrild, H.; Levin, K.; Lervang, H. H.; Kolendorf, K.; Krarup, T.; Schmitz, O.; Zdravkovic, M.; Le-Thi, T.; Madsbad, S. Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic p-cell function and arginine-stimulated insulin secretion during hyperglycemia in patients with type 2 diabetes mellitus. Diabet. Med., 2008, 25(2), 152-156. (Pubitemid 351293400)
-
(2008)
Diabetic Medicine
, vol.25
, Issue.2
, pp. 152-156
-
-
Vilsboll, T.1
Brock, B.2
Perrild, H.3
Levin, K.4
Lervang, H.-H.5
Kolendorf, K.6
Krarup, T.7
Schmitz, O.8
Zdravkovic, M.9
Le-Thi, T.10
Madsbad, S.11
-
117
-
-
50649110233
-
Liraglutide, a once-daily human glucagon-like peptide-1 analogue, shows beneficial effects on cardiovascular risk biomarkers in patients with type 2 diabetes
-
Courreges, J. P.; Zdravkovic, M.; Vilsboll, T.; Zdravkovic, M.; Lethi, T.; Krarup, T.; Schmitz, O.; Verhoeven. R.; Buganova, I.; Madsbad, S. Liraglutide, a once-daily human glucagon-like peptide-1 analogue, shows beneficial effects on cardiovascular risk biomarkers in patients with type 2 diabetes. Diabet. Med., 2008, 25(9), 1129-1131.
-
(2008)
Diabet. Med.
, vol.25
, Issue.9
, pp. 1129-1131
-
-
Courreges, J.P.1
Zdravkovic, M.2
Vilsboll, T.3
Zdravkovic, M.4
Lethi, T.5
Krarup, T.6
Schmitz, O.7
Verhoeven, R.8
Buganova, I.9
Madsbad, S.10
-
118
-
-
70849096647
-
Effect of renal impairment on the pharmacokinetics of the GLP-1 analogue liraglutide
-
Jacobsen, L. V.; Hindsberger, C.; Robson, R.; Zdravkovic, M. Effect of renal impairment on the pharmacokinetics of the GLP-1 analogue liraglutide. Br. J. Clin. Pharmacol, 2009, 68(6), 898-905.
-
(2009)
Br. J. Clin. Pharmacol.
, vol.68
, Issue.6
, pp. 898-905
-
-
Jacobsen, L.V.1
Hindsberger, C.2
Robson, R.3
Zdravkovic, M.4
-
119
-
-
33646161943
-
Inhibition of Glucagon Secretion
-
DOI 10.1016/S1054-3589(05)52008-8, PII S1054358905520088, Amylin: Physiology and Pharmacology
-
Young, A. Inhibition of glucagon secretion. Adv. Pharmacol, 2005, 52, 151-171. (Pubitemid 43631254)
-
(2005)
Advances in Pharmacology
, vol.52
, pp. 151-171
-
-
Young, A.1
-
120
-
-
0029063901
-
Gstric emptying is accelerated in diabetic BB rats and is slowed by subcutaneous injections of amylin
-
Young, A. A.; Gedulin, B.; Vine, W.; Percy, A.; Rink, T. J. Gstric emptying is accelerated in diabetic BB rats and is slowed by subcutaneous injections of amylin. Diabetologia, 1995, 38(6), 642-648.
-
(1995)
Diabetologia
, vol.38
, Issue.6
, pp. 642-648
-
-
Young, A.A.1
Gedulin, B.2
Vine, W.3
Percy, A.4
Rink, T.J.5
-
121
-
-
0031037318
-
Dose-response for glucagonostatic effect of amylin in rats
-
DOI 10.1016/S0026-0495(97)90170-0
-
Gedulin, B. R.; Rink, T. J.; Young, A. A. Doseresponse for glucagonostatic effect of amylin in rats. Metabolism, 1997, 46(1), 67-70. (Pubitemid 27052027)
-
(1997)
Metabolism: Clinical and Experimental
, vol.46
, Issue.1
, pp. 67-70
-
-
Gedulin, B.R.1
Rink, T.J.2
Young, A.A.3
-
122
-
-
0034972374
-
The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema/nucleus of the solitary tract (AP/NTS) lesioned rats
-
DOI 10.1038/sj.ijo.0801664
-
Lutz, T. A.; Mollet, A.; Rushing, P. A.; Riediger, T.; Scharrer, E. The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema/nucleus of the solitary tract (AP/NTS) lesioned rats. Int. J. Obes. Relat. Metab. Disord., 2001, 258(7), 1005-1011. (Pubitemid 32566055)
-
(2001)
International Journal of Obesity
, vol.25
, Issue.7
, pp. 1005-1011
-
-
Lutz, T.A.1
Mollet, A.2
Rushing, P.A.3
Riediger, T.4
Scharrer, E.5
-
123
-
-
0036548068
-
A randomized study and open-label extension evaluating the long-term efficacy of pramlintide as an adjunct to insulin therapy in type 1 diabetes
-
DOI 10.2337/diacare.25.4.724
-
Whitehouse, F.; Kruger, D. F.; Fineman, M.; Shen, L.; Ruggles, J. A.; Maggs, D. G.; Weyer, C.; Kolterman, O. G. A randomized study and open-label extension evaluating the long-term efficacy of pramlinitide as an adjunct to insulin therapy in type 1 diabetes. Diabetes Care, 2002, 25(4), 724-730. (Pubitemid 41071194)
-
(2002)
Diabetes Care
, vol.25
, Issue.4
, pp. 724-730
-
-
Whitehouse, F.1
Kruger, D.F.2
Fineman, M.3
Shen, L.4
Ruggles, J.A.5
Maggs, D.G.6
Weyer, C.7
Kolterman, O.G.8
-
124
-
-
8144228619
-
Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: A 1-year, randomized controlled trial
-
DOI 10.1111/j.1464-5491.2004.01319.x
-
Ratner, R. E.; Dickey, R.; Fineman, M.; Maggs, D. G.; Shen, L.; Strobel, S. A.; Weyer, C.; Kolterman, O. G. Amylin replacement with pramlinitide as an adjunct to insulin therapy improves longterm glycaemic and weight control in type 1 diabetes mellitus: a 1-year randomized controlled trial. Diabet. Med., 2004, 21(11), 1204-1212. (Pubitemid 39472376)
-
(2004)
Diabetic Medicine
, vol.21
, Issue.11
, pp. 1204-1212
-
-
Ratner, R.E.1
Dickey, R.2
Fineman, M.3
Maggs, D.G.4
Shen, L.5
Strobel, S.A.6
Weyer, C.7
Kolterman, O.G.8
-
125
-
-
18844392661
-
Effect of pramlintide on satiety and food intake in obese subjects and subjects with type 2 diabetes
-
DOI 10.1007/s00125-005-1732-4
-
Chapman, I.; Parker, B.; Doran, S.; Feinle-Bisset, C.; Wishart, J.; Strobel, S.; Wang, Y.; Burns, C.; Lush, C.; Weyer, C.; Horowitz, M. Effect of pramlinitide on satiety and food intake in obese subjects and subjects with type 2 diabetes. Diabetologia, 2005, 48(5), 838-848. (Pubitemid 40767975)
-
(2005)
Diabetologia
, vol.48
, Issue.5
, pp. 838-848
-
-
Chapman, I.1
Parker, B.2
Doran, S.3
Feinle-Bisset, C.4
Wishart, J.5
Strobel, S.6
Wang, Y.7
Burns, C.8
Lush, C.9
Weyer, C.10
Horowitz, M.11
-
126
-
-
0042167233
-
Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: A 1-year randomized controlled trial
-
DOI 10.2337/diacare.26.3.784
-
Hollander, P. A.; Levy, P.; Fineman, M. S.; Maggs, D. G.; Shen, L. Z.; Strobel, S. A.; Weyer, C.; Kolterman, O. G. Pramlinitide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: a 1-year randomized controlled trial. Diabetes Care, 2003, 26(3), 784-790. (Pubitemid 36929344)
-
(2003)
Diabetes Care
, vol.26
, Issue.3
, pp. 784-790
-
-
Hollander, P.A.1
Levy, P.2
Fineman, M.S.3
Maggs, D.G.4
Shen, L.Z.5
Strobel, S.A.6
Weyer, C.7
Kolterman, O.G.8
-
127
-
-
36048998480
-
Pramlintide improved glycemic control and reduced weight in patients with type 2 diabetes using basal insulin
-
DOI 10.2337/dc07-0589
-
Riddle, M.; Brown, C.; Frias, J.; Lutz, K.; Zhang, B.; Kolterman, O.; Maier, H. Pramlintide improved glycemic control and reduced weight in patients with type 2 diabetes using basal insulin. Diabetes Care, 2007, 30(11), 2794-2799. (Pubitemid 350083120)
-
(2007)
Diabetes Care
, vol.30
, Issue.11
, pp. 2794-2799
-
-
Riddle, M.1
Frias, J.2
Zhang, B.3
Maier, H.4
Brown, C.5
Lutz, K.6
Kolterman, O.7
-
128
-
-
79951588450
-
-
Available from, Accessed Jan 15, 2011
-
Available from URL:http://documents.symlin.com/SYM-LIN-PI.pd (Accessed Jan 15, 2011).
-
-
-
-
129
-
-
40249120466
-
American diabetes association. Standards of medical care in diabetes-2008
-
American Diabetes Association. Standards of Medical Care in Diabetes-2008. Diabetes Care, 2008, 31, S12-S54.
-
(2007)
Diabetes Care
, vol.31
-
-
-
130
-
-
33947243803
-
Glycated albumin is a better glycemic indicator than glycated hemoglobin values in hemodialysis patients with diabetes: Effect of anemia and erythropoietin injection
-
DOI 10.1681/ASN.2006070772
-
Inaba, M.; Okuno, S.; Kumeda, Y.; Yamada, S.; Imanishi, Y.; Tabata T.; Okamura M.; Okada, S.; Yamakawa T.; Ishimura, E.; Nishizawa, Y. The Osaka CKD Expert Research Group. Glycated albumin is a better glycemic indicator than glycated hemoglobin values in hemodialysis patients with diabetes: effect of anemia and erythropoietin injection. J. Am. Soc. Nephrol., 2007, 18(3), 896-903. (Pubitemid 46434506)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.3
, pp. 896-903
-
-
Inaba, M.1
Okuno, S.2
Kumeda, Y.3
Yamada, S.4
Imanishi, Y.5
Tabata, T.6
Okamura, M.7
Okada, S.8
Yamakawa, T.9
Ishimura, E.10
Nishizawa, Y.11
-
131
-
-
42149123415
-
1c levels in diabetic subjects on hemodialysis
-
DOI 10.1038/ki.2008.25, PII KI200825
-
Peacock, T. P.; Shihabi, Z. K.; Bleyer, A. J.; Dolbare, E. L.; Byers, J. R.; Knovich, M. A.; Calles-Escandon, J.; Russell, G. B.; Freedman, B. I. Comparison of glycated albumin and hemoglobin A1c levels in diabetic subjects on hemodialysis. Kidney Int., 2008, 73(9), 1062-1068. (Pubitemid 351543905)
-
(2008)
Kidney International
, vol.73
, Issue.9
, pp. 1062-1068
-
-
Peacock, T.P.1
Shihabi, Z.K.2
Bleyer, A.J.3
Dolbare, E.L.4
Byers, J.R.5
Knovich, M.A.6
Calles-Escandon, J.7
Russell, G.B.8
Freedman, B.I.9
-
132
-
-
50249186315
-
Glycated hemoglobin or glycated albumin for assessment of glycemic control in dialysis patients with diabetes?
-
Abe, M.; Matsumoto, K. Glycated hemoglobin or glycated albumin for assessment of glycemic control in dialysis patients with diabetes? Nat. Clin. Pract. Nephrol., 2008, 4(9), 482-483.
-
(2008)
Nat. Clin. Pract. Nephrol.
, vol.4
, Issue.9
, pp. 482-483
-
-
Abe, M.1
Matsumoto, K.2
|