Practical synthesis of precursor of [N-methyl- 11C]vorozole, an efficient PET tracer targeting aromatase in the brain

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 4, 2011, Pages 1464-1470

  Takahashi, Kayo ^a   Yamagishi, Gen ^b   Hiramatsu, Toshiyuki ^b,c   Hosoya, Ayako ^b,c   Onoe, Kayo ^a   Doi, Hisashi ^a   Nagata, Hiroko ^a   Wada, Yasuhiro ^a   Onoe, Hirotaka ^a   Watanabe, Yasuyoshi ^a   Hosoya, Takamitsu ^b,c  

^a RIKEN   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Aromatase inhibitor; Carbon 11; Positron emission tomography (PET); Vorozole

Indexed keywords

AROMATASE; CARBON N METHYL VOROZOLE C 11; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRAIN; CHIRALITY; DRUG SYNTHESIS; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RHESUS MONKEY;

ANIMALS; AROMATASE; AROMATASE INHIBITORS; BRAIN; BRAIN CHEMISTRY; MACACA MULATTA; MALE; POSITRON-EMISSION TOMOGRAPHY; STEREOISOMERISM; TRIAZOLES;

MACACA MULATTA;

EID: 79951551146     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.12.057     Document Type: Article

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