Reinvestigation of the synthesis and evaluation of [N-methyl-11C]vorozole, a radiotracer targeting cytochrome P450 aromatase

Nuclear Medicine and Biology

Volumn 36, Issue 3, 2009, Pages 323-334

  Kim, Sung Won ^a   Biegon, Anat ^a   Katsamanis, Zachary E ^a   Ehrlich, Carolin W ^b   Hooker, Jacob M ^a   Shea, Colleen ^a   Muench, Lisa ^c   Xu, Youwen ^a   King, Payton ^a   Carter, Pauline ^a   Alexoff, David L ^a   Fowler, Joanna S ^a,d,e  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e STONY BROOK UNIVERSITY   (United States)

Author keywords

N methyl 11C vorozole; Breast cancer; Estrogen; Positron emission tomography; Steroid abuse

Indexed keywords

AROMATASE; AROMATASE INHIBITOR; CYTOCHROME P450; LETROZOLE; METHYL IODIDE; N METHYL VOROZOLE C 11; NORVOROZOLE; RADIOPHARMACEUTICAL AGENT; SILICON DIOXIDE; UNCLASSIFIED DRUG;

AMYGDALOID NUCLEUS; ARTICLE; BRAIN REGION; DRUG SCREENING; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POSITRON EMISSION TOMOGRAPHY; PREOPTIC AREA;

ALKYLATION; ANIMALS; AROMATASE; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HYDROCARBONS, IODINATED; MAGNETIC RESONANCE SPECTROSCOPY; PAPIO; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS; STEREOISOMERISM; TIME FACTORS; TRIAZOLES;

EID: 62549123348     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2008.12.013     Document Type: Article

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