메뉴 건너뛰기




Volumn 19, Issue 3, 2001, Pages 881-894

Aromatase inhibitors in the treatment and prevention of breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLUTETHIMIDE; ANASTROZOLE; AROMATASE INHIBITOR; EXEMESTANE; FADROZOLE; FORMESTANE; LETROZOLE; PYRIDOGLUTETHIMIDE; TAMOXIFEN; VOROZOLE;

EID: 0035253379     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2001.19.3.881     Document Type: Review
Times cited : (304)

References (111)
  • 4
    • 0000840138 scopus 로고
    • Role of extraglandular estrogen in human endocrinology
    • Greep RO, Astwood EB (eds): Handbook of Physiology. Washington, DC, American Physiological Society
    • (1973) , pp. 619-629
    • Siiteri, P.K.1    MacDonald, P.C.2
  • 6
    • 0031663593 scopus 로고    scopus 로고
    • In vivo inhibition of aromatization by exemestane, a novel irreversible aromatase inhibitor, in postmenopausal breast cancer patients
    • (1998) Clin Cancer Res , vol.4 , pp. 2089-2093
    • Geisler, J.1    King, N.2    Anker, G.3
  • 7
    • 0030057071 scopus 로고    scopus 로고
    • Pharmacology of new aromatase inhibitors
    • (1996) Breast , vol.5 , pp. 206-208
    • Lonning, P.E.1
  • 12
    • 0025169332 scopus 로고
    • The clinical and endocrine effects of 4-hydroxyandrostenedione alone and in combination with goserelin in premenopausal women with advanced breast cancer
    • (1990) Br J Cancer , vol.62 , pp. 679-683
    • Stein, R.C.1    Dowsett, M.2    Hedley, A.3
  • 15
    • 0000047030 scopus 로고    scopus 로고
    • Preclinical studies using the intratumoral aromatase model for postmenopausal breast cancer
    • (1998) Oncology , vol.12 , Issue.SUPPL. 5 , pp. 36-40
    • Brodie, A.1    Lu, Q.2    Liu, Y.3
  • 19
    • 0027131199 scopus 로고
    • A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1622-1628
    • Bulun, S.E.1    Price, T.M.2    Mahendroo, M.S.3
  • 26
    • 0033050076 scopus 로고    scopus 로고
    • Aromatase overexpression and breast hyperplasia, an in vivo model: Continued overexpression of aromatase is sufficient to maintain hyperplasia without circulating estrogens, and aromatase inhibitors abrogate these preneoplastic changes in mammary glands
    • (1999) Endocr Relat Cancer , vol.6 , pp. 307-314
    • Tekmal, R.R.1    Kirma, N.2    Gill, K.3
  • 29
    • 0026524574 scopus 로고
    • Aromatase activity and estradiol in human breast cancer: Its relationship to estradiol and epidermal growth factor receptors and to tumor-node-metastasis staging
    • (1992) J Clin Oncol , vol.10 , pp. 438-446
    • Bolufer, P.1    Ricart, E.2    Luch, A.3
  • 36
    • 0031457952 scopus 로고    scopus 로고
    • Animal models of breast cancer: Experimental design and their use in nutrition and psychosocial research
    • (1997) Br Cancer Res Treat , vol.46 , pp. 117-133
    • Clarke, R.1
  • 39
    • 0027985528 scopus 로고
    • A nude mouse model for postmenopausal breast cancer using MCF-7 cells transfected with the human aromatase gene
    • (1994) Cancer Res , vol.54 , pp. 5092-5095
    • Yue, W.1    Zhou, D.2    Chen, S.3
  • 42
    • 0000151275 scopus 로고    scopus 로고
    • Pharmacology of inhibitors of estrogen biosynthesis
    • Oettel M, Schillinger E (eds): Estrogens, Antiestrogens II: Pharmacology and Clinical Application of Estrogens and Antiestrogens. Berlin Heidelberg, Springer
    • (1999) , vol.135 , Issue.2 , pp. 223-230
    • Bhatnagar, A.S.1    Miller, W.R.2
  • 43
    • 0029741056 scopus 로고    scopus 로고
    • Aromatase inhibitors: Rationale for use following anti-oestrogen therapy
    • (1996) Semin Oncol , vol.23 , Issue.SUPPL. 9 , pp. 21-27
    • Yue, W.1    Santen, R.2
  • 44
    • 0023760993 scopus 로고
    • Development of tamoxifen-stimulated growth of MCF-7 tumors in athymic mice after long-term antiestrogen administration
    • (1988) Cancer Res , vol.48 , pp. 5183-5187
    • Gottardis, M.M.1    Jordan, V.C.2
  • 46
    • 0031054095 scopus 로고    scopus 로고
    • A phase III trial comparing anastrozole (1 and 10 milligrams), a potent and selective aromatase inhibitor, with megestrol acetate in postmenopausal women with advanced breast cancer: The Arimidex Study Group
    • (1997) Cancer , vol.79 , pp. 730-739
    • Buzdar, A.1    Jones, S.E.2    Vogel, C.3
  • 47
    • 9244245282 scopus 로고    scopus 로고
    • A randomised trial comparing two doses of the new selective aromatase inhibitor anastrozole (Arimidex) with megestrol acetate in postmenopausal patients with advanced breast cancer: The Arimidex Study Group
    • (1996) Eur J Cancer , vol.32 A , pp. 404-412
    • Jonat, W.1    Howell, A.2    Blomqvist, C.3
  • 48
    • 8944237006 scopus 로고    scopus 로고
    • Anastrozole, a potent and selective aromatase inhibitor, versus megestrol acetate in postmenopausal women with advanced breast cancer: Results of overview and analysis of two phase III clinical trials - The Arimidex Study Group
    • (1996) J Clin Oncol , vol.14 , pp. 2000-2011
    • Buzdar, A.1    Jonat, W.2    Howell, A.3
  • 49
    • 0032530988 scopus 로고    scopus 로고
    • Anastrozole versus megestrol acetate in the treatment of postmenopausal women with advanced breast carcinoma: The Arimidex Study Group
    • (1998) Cancer , vol.83 , pp. 1142-1152
    • Buzdar, A.1    Jonat, W.2    Howell, A.3
  • 50
    • 7344242595 scopus 로고    scopus 로고
    • Letrozole, a new oral aromatase inhibitor: Randomised trial comparing 2.5 mg daily, 0.5 mg daily and aminoglutethimide in postmenopausal women with advanced breast cancer - The Letrozole International Trial Group
    • (1998) Ann Oncol , vol.9 , pp. 639-645
    • Gershanovich, M.1    Chandri, H.A.2    Campos, D.3
  • 51
    • 0031943424 scopus 로고    scopus 로고
    • Letrozole, a new oral aromatase inhibitor for advanced breast cancer: Double-blind randomized trial showing a dose effect and improved efficacy and tolerability compared with megestrol acetate
    • (1998) J Clin Oncol , vol.16 , pp. 453-461
    • Dombernowsky, P.1    Smith, I.2    Falkson, G.3
  • 52
    • 0000070884 scopus 로고    scopus 로고
    • A phase III trial comparing vorozole (RIVIZOR) versus aminoglutethimide in the treatment of advanced postmenopausal breast cancer: The Vorozole Study Group
    • abstr 656
    • (1997) Eur J Cancer , vol.33 , pp. 148
    • Bengtsson, N.O.1    Focan, C.2    Gudgeon, A.3
  • 54
    • 0032941209 scopus 로고    scopus 로고
    • Randomized phase m trial comparing the new potent and selective third-generation aromatase inhibitor vorozole with megestrol acetate in postmenopausal advanced breast cancer patients: The North American Vorozole Study Group
    • (1999) J Clin Oncol , vol.17 , pp. 52-63
    • Goss, P.E.1    Winer, E.P.2    Tannock, I.F.3
  • 55
    • 0034128928 scopus 로고    scopus 로고
    • Exemestane is superior to megestrol acetate after tamoxifen failure in postmenopausal women with advanced breast cancer: Results of a phase III randomized double-blind trial - The Exemestane Study Group
    • (2000) J Clin Oncol , vol.18 , pp. 1399-1411
    • Kaufmann, M.1    Bajetta, E.2    Dirix, L.Y.3
  • 56
    • 0032907539 scopus 로고    scopus 로고
    • The third-generation non-steroidal aromatase inhibitors: A review of their clinical benefits in the second-line hormonal treatment of advanced breast cancer
    • (1999) Ann Oncol , vol.10 , pp. 377-384
    • Hamilton, A.1    Piccart, M.2
  • 57
    • 0029940269 scopus 로고    scopus 로고
    • Fadrozole HCl (CGS-16949A) versus megestrol acetate treatment of postmenopausal patients with metastatic breast carcinoma: The Multi-Institutional Trialist Collaborative Study Group
    • (1996) Cancer , vol.77 , pp. 2503-2513
    • Buzdar, A.1    Smith, R.2    Vogel, C.3
  • 58
    • 0343924363 scopus 로고    scopus 로고
    • Formestane versus megestrol acetate in postmenopausal breast cancer patients after failure of tamoxifen: A phase III prospective randomised cross over trial of second-line hormonal treatment - The Swiss Group for Clinical Cancer Res
    • (1997) Eur J Cancer , vol.33 , pp. 1017-1024
    • Thürlimann, B.1    Castiglione, M.2    Hsu-Schmitz, S.F.3
  • 61
    • 0032729804 scopus 로고    scopus 로고
    • Multicenter, phase II trial of exemestane as third-line hormonal therapy of postmenopausal women with metastatic breast cancer
    • (1999) J Clin Oncol , vol.17 , pp. 3418-3425
    • Jones, S.1    Vogel, C.2    Arkhipov, A.3
  • 62
    • 0000340799 scopus 로고    scopus 로고
    • A phase II confirmatory study of antitumor efficacy and safety of exemestane (EXE) as third-line hormonal treatment of postmenopausal patients (pts) with metastatic breast cancer (MBC) refractory to tamoxifen (Tam) and Megace
    • abstr 437
    • (1998) Breast Cancer , vol.50 , pp. 305
    • Jones, S.1    Chang, A.2    Lusch, C.3
  • 63
    • 0032851270 scopus 로고    scopus 로고
    • Vorozole results in greater oestrogen suppression than formestane in postmenopausal women and when added to goserelin in premenopausal women with advanced breast cancer
    • (1999) Br Cancer Res Treat , vol.56 , pp. 25-34
    • Dowsett, M.1    Doody, D.2    Miall, S.3
  • 65
    • 0029031797 scopus 로고
    • Aromatase inhibition with 4-OHAndrostenedione after prior aromatase inhibition with aminoglutethimide in women with advanced breast cancer
    • (1995) Br Cancer Res Treat , vol.35 , pp. 249-253
    • Murray, R.1    Pitt, P.2
  • 66
    • 0345596372 scopus 로고    scopus 로고
    • Third-line hormonal treatment with exemestane in postmenopausal patients with advanced breast cancer progressing on aminoglutethimide: A phase II multicentre multinational study - The Exemestane Study Group
    • (1997) Eur J Cancer , vol.33 , pp. 1767-1773
    • Thuerlimann, B.1    Paridaens, R.2    Serin, D.3
  • 73
    • 0027953320 scopus 로고
    • Hormonal treatment of metastatic breast cancer: An Eastern Cooperative Oncology Group Phase III trial comparing aminoglutethimide to tamoxifen
    • (1994) Cancer , vol.73 , pp. 354-361
    • Gale, K.E.1    Andersen, J.W.2    Tormey, D.C.3
  • 74
    • 0038478620 scopus 로고    scopus 로고
    • First-line fadrozole HCl (CGS 16949A) versus tamoxifen in postmenopausal women with advanced breast cancer: The Swiss Group for Clinical Cancer Res (SAKK)
    • (1996) Ann Oncol , vol.7 , pp. 471-479
    • Thuerlimann, B.1    Beretta, K.2    Bacchi, M.3
  • 80
  • 82
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomised trials
    • (1998) Lancet , vol.351 , pp. 1451-1467
  • 86
    • 0028594068 scopus 로고
    • Chemopreventive effects of the aromatase inhibitors vorozole (R-83842) and 4-hydroxyandrostenedione in the methylnitrosourea (MNU)-induced mammary tumor model in Sprague-Dawley rats
    • (1994) Carcinogenesis , vol.15 , pp. 2775-2780
    • Lubet, R.A.1    Steele, V.E.2    Casebolt, T.L.3
  • 91
    • 0032805333 scopus 로고    scopus 로고
    • Premenopausal breast cancer patients treated with a gonadotropin-releasing hormone analog alone or in combination with an aromatase inhibitor: A comparative endocrine study
    • (1999) Anticancer Res , vol.19 , pp. 2261-2268
    • Celio, L.1    Martinetti, A.2    Ferrari, L.3
  • 98
    • 0021277467 scopus 로고
    • Treatment of disseminated breast cancer with tamoxifen, aminoglutethimide, hydrocortisone, and danazol, used in combination or sequentially
    • (1984) Lancet , vol.1 , pp. 1369-1372
    • Powles, T.J.1    Ashley, S.2    Ford, H.T.3
  • 104
    • 0030845035 scopus 로고    scopus 로고
    • Megestrol acetate and aminoglutethimide/hydrocortisone in sequence or in combination as second-line endocrine therapy of estrogen receptor positive metastatic breast cancer: A Southwest Oncology Group phase III trial
    • (1997) J Clin Oncol , vol.15 , pp. 2494-2501
    • Russell, C.A.1    Green, S.J.2    O'Sullivan, J.3
  • 106
    • 84940622980 scopus 로고
    • Aminoglutethimid plus hochdosiertes Medroxyprogesteronazetat versus Aminoglutethimid plus Kortison in der Therapie des metastasierenden Mammakarzinoms
    • (1987) Onkologie , vol.10 , pp. 321-323
    • Wander, H.E.1    Kleeberg, U.R.2    Esser, U.3
  • 107
    • 0006292374 scopus 로고    scopus 로고
    • Qualitative effects of letrozole as primary medical therapy on in situ oestrogen synthesis and endogenous oestrogen levels within the breast
    • abstr 0-12
    • (1997) Breast , vol.6 , pp. 228
    • Miller, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.