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Volumn 405, Issue 4, 1999, Pages 472-490

Ultrastructural localization of dynorphin in the dentate gyrus in human temporal lobe epilepsy: A study of reorganized mossy fiber synapses

Author keywords

Axonal sprouting; Dense core vesicles; Electron microscopy; Hippocampus; Perforated synapses; Plasticity

Indexed keywords

DYNORPHIN;

EID: 0033594229     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19990322)405:4<472::AID-CNE3>3.0.CO;2-P     Document Type: Article
Times cited : (69)

References (102)
  • 1
    • 0041709922 scopus 로고    scopus 로고
    • GABAergic cells are the major postsynaptic targets of mossy fibers in the rat hippocampus
    • Acsády L, Kamondi A, Sik A, Freund T, Buzsáki G. 1998. GABAergic cells are the major postsynaptic targets of mossy fibers in the rat hippocampus. J Neurosci 18:3386-3403.
    • (1998) J Neurosci , vol.18 , pp. 3386-3403
    • Acsády, L.1    Kamondi, A.2    Sik, A.3    Freund, T.4    Buzsáki, G.5
  • 2
    • 0018769536 scopus 로고
    • Synaptic extensions from the mossy fibers of the fascia dentata
    • Amaral DG. 1979. Synaptic extensions from the mossy fibers of the fascia dentata. Anat Embryol 155:241-251.
    • (1979) Anat Embryol , vol.155 , pp. 241-251
    • Amaral, D.G.1
  • 3
    • 0019433958 scopus 로고
    • Development of the mossy fibers of the dentate gyrus: I. A light and electron microscopic study of the mossy fibers and their expansions
    • Amaral DG, Dent JA. 1981. Development of the mossy fibers of the dentate gyrus: I. A light and electron microscopic study of the mossy fibers and their expansions. J Comp Neurol 195:51-86.
    • (1981) J Comp Neurol , vol.195 , pp. 51-86
    • Amaral, D.G.1    Dent, J.A.2
  • 5
    • 0027281866 scopus 로고
    • The neuropathology of temporal lobe epilepsy
    • Armstrong DD. 1993. The neuropathology of temporal lobe epilepsy. J Neuropathol Exp Neurol 52:433-443.
    • (1993) J Neuropathol Exp Neurol , vol.52 , pp. 433-443
    • Armstrong, D.D.1
  • 7
    • 0003159629 scopus 로고
    • Aberrant synaptic reorganization in human epileptic hippocampus: Evidence for feed-forward excitation
    • Babb TL, Pretorius JK, Kupfer WR, Mathern GW, Crandall PH, Levesque MF. 1992. Aberrant synaptic reorganization in human epileptic hippocampus: evidence for feed-forward excitation. Dendron 1:7-25.
    • (1992) Dendron , vol.1 , pp. 7-25
    • Babb, T.L.1    Pretorius, J.K.2    Kupfer, W.R.3    Mathern, G.W.4    Crandall, P.H.5    Levesque, M.F.6
  • 8
    • 0025299049 scopus 로고
    • Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus
    • Ben-Ari Y, Represa A. 1990. Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus. Trends Neurosci 13:312-318.
    • (1990) Trends Neurosci , vol.13 , pp. 312-318
    • Ben-Ari, Y.1    Represa, A.2
  • 9
    • 73049129675 scopus 로고
    • Special axo-dendritic synapses in the hippocampal cortex: Electron and light microscopic studies on the layer of mossy fibers
    • Blackstad TW, Kjaerheim A. 1961. Special axo-dendritic synapses in the hippocampal cortex: electron and light microscopic studies on the layer of mossy fibers. J Comp Neurol 117:133-159.
    • (1961) J Comp Neurol , vol.117 , pp. 133-159
    • Blackstad, T.W.1    Kjaerheim, A.2
  • 10
    • 0029806084 scopus 로고    scopus 로고
    • Altered distribution of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit GluR2(4) and the N-methyl-D-aspartate receptor subunit NMDAR1 in the hippocampus of patients with temporal lobe epilepsy
    • Blümcke I, Beck H, Scheffler B, Hof PR, Morrison JH, Wolf HK, Schramm J, Elger CE, Wiestler OD. 1996. Altered distribution of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit GluR2(4) and the N-methyl-D-aspartate receptor subunit NMDAR1 in the hippocampus of patients with temporal lobe epilepsy. Acta Neuropathol 92:596-587.
    • (1996) Acta Neuropathol , vol.92 , pp. 596-1587
    • Blümcke, I.1    Beck, H.2    Scheffler, B.3    Hof, P.R.4    Morrison, J.H.5    Wolf, H.K.6    Schramm, J.7    Elger, C.E.8    Wiestler, O.D.9
  • 11
    • 0025696512 scopus 로고
    • Distribution of glutamate-like immunoreactivity in excitatory hippocampal pathways: A semiquantitative electron microscopic study in rats
    • Bramham CR, Torp R, Zhang N, Storm-Mathisen J, Ottersen OP. 1990. Distribution of glutamate-like immunoreactivity in excitatory hippocampal pathways: a semiquantitative electron microscopic study in rats. Neuroscience 39:405-417.
    • (1990) Neuroscience , vol.39 , pp. 405-417
    • Bramham, C.R.1    Torp, R.2    Zhang, N.3    Storm-Mathisen, J.4    Ottersen, O.P.5
  • 13
    • 0029798061 scopus 로고    scopus 로고
    • Induction of long-term potentiation is associated with major ultrastructural changes of activated synapses
    • Buchs P-A, Muller D. 1996. Induction of long-term potentiation is associated with major ultrastructural changes of activated synapses. Proc Natl Acad Sci USA 93:8040-8045.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8040-8045
    • Buchs, P.-A.1    Muller, D.2
  • 14
    • 0030773376 scopus 로고    scopus 로고
    • Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats
    • Buckmaster PS, Dudek FE. 1997. Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats. J Comp Neurol 385:385-404.
    • (1997) J Comp Neurol , vol.385 , pp. 385-404
    • Buckmaster, P.S.1    Dudek, F.E.2
  • 15
    • 0007621806 scopus 로고
    • Plasticity in the central nervous system: Do synapses divide?
    • Carlin RK, Siekevitz P. 1983. Plasticity in the central nervous system: do synapses divide? Proc Natl Acad Sci USA 80:3517-3521.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 3517-3521
    • Carlin, R.K.1    Siekevitz, P.2
  • 16
    • 0021957487 scopus 로고
    • Characterization of the prodynorphin and proenkephalin neuropeptide systems in rat hippocampus
    • Chavkin C, Shoemaker WJ, McGinty JF, Bayon A, Bloom FE. 1985. Characterization of the prodynorphin and proenkephalin neuropeptide systems in rat hippocampus. J Neurosci 5:808-816.
    • (1985) J Neurosci , vol.5 , pp. 808-816
    • Chavkin, C.1    Shoemaker, W.J.2    McGinty, J.F.3    Bayon, A.4    Bloom, F.E.5
  • 17
    • 0026778684 scopus 로고
    • Three-dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus
    • Chicurel ME, Harris KM. 1992. Three-dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus. J Comp Neurol 325:169-182.
    • (1992) J Comp Neurol , vol.325 , pp. 169-182
    • Chicurel, M.E.1    Harris, K.M.2
  • 19
    • 0022459849 scopus 로고
    • A light and electron microscopic analysis of the mossy fibers of the rat dentate gyrus
    • Claiborne BJ, Amaral DG, Cowan WM. 1986. A light and electron microscopic analysis of the mossy fibers of the rat dentate gyrus. J Comp Neurol 246:435-458.
    • (1986) J Comp Neurol , vol.246 , pp. 435-458
    • Claiborne, B.J.1    Amaral, D.G.2    Cowan, W.M.3
  • 20
    • 0029097364 scopus 로고
    • Ultrastructural heterogeneity of enkephalin-containing terminals in the rat hippocampal formation
    • Commons KG, Milner TA. 1995. Ultrastructural heterogeneity of enkephalin-containing terminals in the rat hippocampal formation. J Comp Neurol 358:324-342.
    • (1995) J Comp Neurol , vol.358 , pp. 324-342
    • Commons, K.G.1    Milner, T.A.2
  • 21
    • 0026558337 scopus 로고
    • Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fibers
    • Cronin J, Obenaus A, Houser CR, Dudek FE. 1992. Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fibers. Brain Res 573:305-310.
    • (1992) Brain Res , vol.573 , pp. 305-310
    • Cronin, J.1    Obenaus, A.2    Houser, C.R.3    Dudek, F.E.4
  • 22
    • 0024412565 scopus 로고
    • Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy
    • de Lanerolle NC, Kim JH, Robbins RJ, Spencer DD. 1989. Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy. Brain Res 495:387-395.
    • (1989) Brain Res , vol.495 , pp. 387-395
    • Lanerolle, N.C.1    Kim, J.H.2    Robbins, R.J.3    Spencer, D.D.4
  • 25
    • 0028846955 scopus 로고
    • Anatomy and electrophysiology of fast central synapses lead to a structural model for long-term potentiation
    • Edwards FA. 1995a. Anatomy and electrophysiology of fast central synapses lead to a structural model for long-term potentiation. Physiol Rev 75:759-787.
    • (1995) Physiol Rev , vol.75 , pp. 759-787
    • Edwards, F.A.1
  • 26
    • 0029072339 scopus 로고
    • LTP: A structural model to explain the inconsistencies
    • Edwards FA. 1995b. LTP: a structural model to explain the inconsistencies. Trends Neurosci 18:250-255.
    • (1995) Trends Neurosci , vol.18 , pp. 250-255
    • Edwards, F.A.1
  • 27
    • 0029042668 scopus 로고
    • Physiologic and morphologic characteristics of granule cell circuitry in human epileptic hippocampus
    • Franck JE, Pokorny J, Kunkel DD, Schwartzkroin PA. 1995. Physiologic and morphologic characteristics of granule cell circuitry in human epileptic hippocampus. Epilepsia 36:543-558.
    • (1995) Epilepsia , vol.36 , pp. 543-558
    • Franck, J.E.1    Pokorny, J.2    Kunkel, D.D.3    Schwartzkroin, P.A.4
  • 28
    • 0030337503 scopus 로고    scopus 로고
    • Interneurons of the hippocampus
    • Freund TF, Buzsaki G. 1996. Interneurons of the hippocampus. Hippocampus 6:347-470.
    • (1996) Hippocampus , vol.6 , pp. 347-470
    • Freund, T.F.1    Buzsaki, G.2
  • 29
    • 0020608342 scopus 로고
    • Lesion-induced mossy fibers to the molecular layer of the rat fascia dentata: Identification of postsynaptic granule cells by the Golgi-EM technique
    • Frotscher M, Zimmer J. 1983. Lesion-induced mossy fibers to the molecular layer of the rat fascia dentata: identification of postsynaptic granule cells by the Golgi-EM technique. J Comp Neurol 215:299-311.
    • (1983) J Comp Neurol , vol.215 , pp. 299-311
    • Frotscher, M.1    Zimmer, J.2
  • 30
    • 0023780571 scopus 로고
    • Fine structure of identified neurons in the primate hippocampus: A combined Golgi/EM study in the baboon
    • Frotscher M, Kraft J, Zorn U. 1988. Fine structure of identified neurons in the primate hippocampus: a combined Golgi/EM study in the baboon. J Comp Neurol 275:254-270.
    • (1988) J Comp Neurol , vol.275 , pp. 254-270
    • Frotscher, M.1    Kraft, J.2    Zorn, U.3
  • 31
    • 0023931772 scopus 로고
    • Seizures induce dramatic and distinctly different changes in enkephalin, dynorphin, and CCK immunoreactivities in mouse hippocampal mossy fibers
    • Gall C. 1988. Seizures induce dramatic and distinctly different changes in enkephalin, dynorphin, and CCK immunoreactivities in mouse hippocampal mossy fibers. J Neurosci 8:1852-1862.
    • (1988) J Neurosci , vol.8 , pp. 1852-1862
    • Gall, C.1
  • 32
    • 0026763483 scopus 로고
    • Kappa opioid agonists inhibit transmitter release from guinea pig hippocampal mossy fiber synaptosomes
    • Gannon RL, Terrian DM. 1992. Kappa opioid agonists inhibit transmitter release from guinea pig hippocampal mossy fiber synaptosomes. Neurochem Res 17:741-747.
    • (1992) Neurochem Res , vol.17 , pp. 741-747
    • Gannon, R.L.1    Terrian, D.M.2
  • 33
  • 34
    • 0025186863 scopus 로고
    • Increase in the relative proportion of perforated axospinous synapses following hippocampal kindling is specific for the synaptic field of stimulated axons
    • Geinisman Y, Morrell F, deToledo-Morrell L. 1990. Increase in the relative proportion of perforated axospinous synapses following hippocampal kindling is specific for the synaptic field of stimulated axons. Brain Res 507:325-331.
    • (1990) Brain Res , vol.507 , pp. 325-331
    • Geinisman, Y.1    Morrell, F.2    DeToledo-Morrell, L.3
  • 35
    • 0025935249 scopus 로고
    • Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities
    • Geinisman Y, deToledo-Morrell L, Morrell F. 1991. Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities. Brain Res 566:77-88.
    • (1991) Brain Res , vol.566 , pp. 77-88
    • Geinisman, Y.1    DeToledo-Morrell, L.2    Morrell, F.3
  • 36
    • 0026592361 scopus 로고
    • Increase in the number of axospinous synapses with segmented postsynaptic densities following hippocampal kindling
    • Geinisman Y, Morrell F, deToledo-Morrell L. 1992. Increase in the number of axospinous synapses with segmented postsynaptic densities following hippocampal kindling. Brain Res 569:341-347.
    • (1992) Brain Res , vol.569 , pp. 341-347
    • Geinisman, Y.1    Morrell, F.2    DeToledo-Morrell, L.3
  • 38
    • 0000776425 scopus 로고
    • The fine structure of the mossy fibre endings in the hippocampus of the rabbit
    • Hamlyn LH. 1962. The fine structure of the mossy fibre endings in the hippocampus of the rabbit. J Anat 96:112-120.
    • (1962) J Anat , vol.96 , pp. 112-120
    • Hamlyn, L.H.1
  • 39
    • 0029078073 scopus 로고
    • How multiple-synapse boutons could preserve input specificity during an interneuronal spread of LTP
    • Harris KM. 1995. How multiple-synapse boutons could preserve input specificity during an interneuronal spread of LTP. Trends Neurosci 18:365-369.
    • (1995) Trends Neurosci , vol.18 , pp. 365-369
    • Harris, K.M.1
  • 40
    • 0030949547 scopus 로고    scopus 로고
    • Large amplitude miniature excitatory postsynaptic currents in hippocampal CA3 pyramidal neurons are of mossy fiber origin
    • Henze DA, Card JP, Barrionuevo G, Ben-Ari Y. 1997. Large amplitude miniature excitatory postsynaptic currents in hippocampal CA3 pyramidal neurons are of mossy fiber origin. J Neurophysiol 77:1075-1086.
    • (1997) J Neurophysiol , vol.77 , pp. 1075-1086
    • Henze, D.A.1    Card, J.P.2    Barrionuevo, G.3    Ben-Ari, Y.4
  • 41
    • 0023323634 scopus 로고
    • Electron microscopic study of mossy fiber endings of the hippocampal formation in El mice
    • Hochi T, Watanabe H, Mizukawa K, Otsuka N. 1987. Electron microscopic study of mossy fiber endings of the hippocampal formation in El mice. Acta Med Okayama 41:81-84.
    • (1987) Acta Med Okayama , vol.41 , pp. 81-84
    • Hochi, T.1    Watanabe, H.2    Mizukawa, K.3    Otsuka, N.4
  • 42
    • 0027033707 scopus 로고
    • Morphological changes in the dentate gyrus in human temporal lobe epilepsy
    • Houser CR. 1992. Morphological changes in the dentate gyrus in human temporal lobe epilepsy. Epilepsy Res Suppl 7:223-234.
    • (1992) Epilepsy Res Suppl , vol.7 , pp. 223-234
    • Houser, C.R.1
  • 43
    • 0025022424 scopus 로고
    • Altered patterns of dynorphin immunoreactivity suggest mossy fiber reorganization in human hippocampal epilepsy
    • Houser CR, Miyashiro JE, Swartz BE, Walsh GO, Rich JR, Delgado-Escueta AV. 1990. Altered patterns of dynorphin immunoreactivity suggest mossy fiber reorganization in human hippocampal epilepsy. J Neurosci 10:267-282.
    • (1990) J Neurosci , vol.10 , pp. 267-282
    • Houser, C.R.1    Miyashiro, J.E.2    Swartz, B.E.3    Walsh, G.O.4    Rich, J.R.5    Delgado-Escueta, A.V.6
  • 44
    • 0027409383 scopus 로고
    • Single mossy fiber axonal systems of human dentate granule cells studied in hippocampal slices from patients with temporal lobe epilepsy
    • Isokawa M, Levesque MF, Babb TL, Engel J. 1993. Single mossy fiber axonal systems of human dentate granule cells studied in hippocampal slices from patients with temporal lobe epilepsy. J Neurosci 13:1511-1522.
    • (1993) J Neurosci , vol.13 , pp. 1511-1522
    • Isokawa, M.1    Levesque, M.F.2    Babb, T.L.3    Engel, J.4
  • 45
    • 0028808612 scopus 로고
    • An analysis of contemporary morphological concepts of synaptic remodelling in the CNS: Perforated synapses revisited
    • Jones DG, Harris RJ. 1995. An analysis of contemporary morphological concepts of synaptic remodelling in the CNS: perforated synapses revisited. Rev Neurosci 6:177-219.
    • (1995) Rev Neurosci , vol.6 , pp. 177-219
    • Jones, D.G.1    Harris, R.J.2
  • 46
    • 0022475065 scopus 로고
    • Kainic acid alters the metabolism of met5-enkephalin and the level of dynorphin A in the rat hippocampus
    • Kanamatsu T, Obie J, Grimes L, McGinty JF, Yoshikawa K, Sabol S, Hong JS. 1986. Kainic acid alters the metabolism of met5-enkephalin and the level of dynorphin A in the rat hippocampus. J Neurosci 6:3094-3102.
    • (1986) J Neurosci , vol.6 , pp. 3094-3102
    • Kanamatsu, T.1    Obie, J.2    Grimes, L.3    McGinty, J.F.4    Yoshikawa, K.5    Sabol, S.6    Hong, J.S.7
  • 47
    • 0022920789 scopus 로고
    • Use of high concentrations of glutaraldehyde for immunocytochemistry of transmitter-synthesizing enzymes in the central nervous system
    • Kosaka T, Nagatsu I, Wu J-Y, Hama K. 1986. Use of high concentrations of glutaraldehyde for immunocytochemistry of transmitter-synthesizing enzymes in the central nervous system. Neuroscience 18:975-990.
    • (1986) Neuroscience , vol.18 , pp. 975-990
    • Kosaka, T.1    Nagatsu, I.2    Wu, J.-Y.3    Hama, K.4
  • 48
    • 0013967252 scopus 로고
    • Electron microscopic studies of the dentate gyrus of the rat. I. Normal structure with special reference to synaptic organization
    • Laatsch RH, Cowan WM. 1966. Electron microscopic studies of the dentate gyrus of the rat. I. Normal structure with special reference to synaptic organization. J Comp Neurol 128:359-396.
    • (1966) J Comp Neurol , vol.128 , pp. 359-396
    • Laatsch, R.H.1    Cowan, W.M.2
  • 49
    • 0030846691 scopus 로고    scopus 로고
    • Connections of the hippocampal formation in humans: I. The mossy fiber pathway
    • Lim C, Blume HW, Madsen JR, Saper CB. 1997. Connections of the hippocampal formation in humans: I. The mossy fiber pathway. J Comp Neurol 385:325-351.
    • (1997) J Comp Neurol , vol.385 , pp. 325-351
    • Lim, C.1    Blume, H.W.2    Madsen, J.R.3    Saper, C.B.4
  • 50
    • 0030909238 scopus 로고    scopus 로고
    • Blockade of pilocarpine- or kainate-induced mossy fiber sprouting by cycloheximide does not prevent subsequent epileptogenesis in rats
    • Longo BM, Mello LEAM. 1997. Blockade of pilocarpine- or kainate-induced mossy fiber sprouting by cycloheximide does not prevent subsequent epileptogenesis in rats. Neurosci Lett 226:163-166.
    • (1997) Neurosci Lett , vol.226 , pp. 163-166
    • Longo, B.M.1    Mello, L.E.A.M.2
  • 51
    • 13144305132 scopus 로고    scopus 로고
    • Chronic stress alters synaptic terminal structure in hippocampus
    • Magarinos AM, Verdugo JMG, McEwen BS. 1997. Chronic stress alters synaptic terminal structure in hippocampus. Proc Natl Acad Sci USA 94:14002-14008.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14002-14008
    • Magarinos, A.M.1    Verdugo, J.M.G.2    McEwen, B.S.3
  • 53
    • 0013950709 scopus 로고
    • Epilepsy and the temporal lobes: A clinical encephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes
    • Margerison JH, Corsellis JAN. 1966. Epilepsy and the temporal lobes: a clinical encephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes. Brain 89:499-530.
    • (1966) Brain , vol.89 , pp. 499-530
    • Margerison, J.H.1    Corsellis, J.A.N.2
  • 54
    • 0026579324 scopus 로고
    • The functional relationship between antidromically evoked field responses of the dentate gyrus and mossy fiber reorganization in temporal lobe epileptic patients
    • Masukawa LM, Uruno K, Sperling M, O'Connor MJ, Burdette LJ. 1992. The functional relationship between antidromically evoked field responses of the dentate gyrus and mossy fiber reorganization in temporal lobe epileptic patients. Brain Res 579:119-127.
    • (1992) Brain Res , vol.579 , pp. 119-127
    • Masukawa, L.M.1    Uruno, K.2    Sperling, M.3    O'Connor, M.J.4    Burdette, L.J.5
  • 56
    • 0020693127 scopus 로고
    • Dynorphin is contained within hippocampal mossy fibers: Immunochemical alterations after kainic acid administration and colchicine-induced neurotoxicity
    • McGinty JF, Henriksen SJ, Goldstein A, Terenius L, Bloom FE. 1983. Dynorphin is contained within hippocampal mossy fibers: immunochemical alterations after kainic acid administration and colchicine-induced neurotoxicity. Proc Natl Acad Sci USA 80:589-593.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 589-593
    • McGinty, J.F.1    Henriksen, S.J.2    Goldstein, A.3    Terenius, L.4    Bloom, F.E.5
  • 58
    • 0029013236 scopus 로고
    • A role for hippocampal opioids in long-term functional plasticity
    • Morris BJ, Johnston HM. 1995. A role for hippocampal opioids in long-term functional plasticity. Trends Neurosci 18:350-355.
    • (1995) Trends Neurosci , vol.18 , pp. 350-355
    • Morris, B.J.1    Johnston, H.M.2
  • 59
    • 0020404692 scopus 로고
    • Perforated postsynaptic densities: Probable intermediates in synapse turnover
    • Nieto-Sampedro M, Hoff SF, Cotman C. 1982. Perforated postsynaptic densities: probable intermediates in synapse turnover. Proc Natl Acad Sci USA 79:5718-5722.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 5718-5722
    • Nieto-Sampedro, M.1    Hoff, S.F.2    Cotman, C.3
  • 60
    • 0025686213 scopus 로고
    • Ultrastructure of the dynorphin-immunoreactivity in rat brain hippocampal mossy fiber system
    • Nitsch C, Riesenberg R. 1990. Ultrastructure of the dynorphin-immunoreactivity in rat brain hippocampal mossy fiber system. Acta Histochem Suppl 38:167-171.
    • (1990) Acta Histochem Suppl , vol.38 , pp. 167-171
    • Nitsch, C.1    Riesenberg, R.2
  • 61
    • 0019498380 scopus 로고
    • Large dense-core vesicle exocytosis and membrane recycling in the mossy fibre synapses of the rabbit hippocampus during epileptiform seizures
    • Nitsch C, Rinne U. 1981. Large dense-core vesicle exocytosis and membrane recycling in the mossy fibre synapses of the rabbit hippocampus during epileptiform seizures. J Neurocytol 10:201-219.
    • (1981) J Neurocytol , vol.10 , pp. 201-219
    • Nitsch, C.1    Rinne, U.2
  • 62
    • 0028911542 scopus 로고
    • Hippocampal mossy fiber sprouting and synapse formation after status epilepticus in rats: Visualization after retrograde transport of biocytin
    • Okazaki MM, Evenson DA, Nadler JV. 1995. Hippocampal mossy fiber sprouting and synapse formation after status epilepticus in rats: visualization after retrograde transport of biocytin. J Comp Neurol 352:515-534.
    • (1995) J Comp Neurol , vol.352 , pp. 515-534
    • Okazaki, M.M.1    Evenson, D.A.2    Nadler, J.V.3
  • 63
    • 0030907041 scopus 로고    scopus 로고
    • Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus
    • Parent JM, Yu TW, Leibowitz RT, Geschwind DH, Sloviter RS, Lowenstein DH. 1997. Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J Neurosci 17:3727-3738.
    • (1997) J Neurosci , vol.17 , pp. 3727-3738
    • Parent, J.M.1    Yu, T.W.2    Leibowitz, R.T.3    Geschwind, D.H.4    Sloviter, R.S.5    Lowenstein, D.H.6
  • 64
    • 0014687804 scopus 로고
    • The small pyramidal neuron of the rat cerebral cortex: The synapses upon dendritic spines
    • Peters A, Kaiserman-Abramof IR. 1969. The small pyramidal neuron of the rat cerebral cortex: the synapses upon dendritic spines. Z Zellforsch 100:487-506
    • (1969) Z Zellforsch , vol.100 , pp. 487-506
    • Peters, A.1    Kaiserman-Abramof, I.R.2
  • 66
    • 0027412952 scopus 로고
    • Cellular substrates for interactions between dynorphin terminals and dopamine dendrites in rat ventral tegmental area and substantia nigra
    • Pickel VM, Chan J, Sesack SR. 1993. Cellular substrates for interactions between dynorphin terminals and dopamine dendrites in rat ventral tegmental area and substantia nigra. Brain Res 602:275-289.
    • (1993) Brain Res , vol.602 , pp. 275-289
    • Pickel, V.M.1    Chan, J.2    Sesack, S.R.3
  • 67
    • 0028914142 scopus 로고
    • Neuropeptide Y and dynorphin-immunoreactive large dense-core vesicles are strategically localized for presynaptic modulation in the hippocampal formation and substantia nigra
    • Pickel VM, Chan J, Veznedaroglu E, Milner TA. 1995. Neuropeptide Y and dynorphin-immunoreactive large dense-core vesicles are strategically localized for presynaptic modulation in the hippocampal formation and substantia nigra. Synapse 19:160-169.
    • (1995) Synapse , vol.19 , pp. 160-169
    • Pickel, V.M.1    Chan, J.2    Veznedaroglu, E.3    Milner, T.A.4
  • 68
    • 0027184309 scopus 로고
    • Epilepsy induced collateral sprouting of hippocampal mossy fibers: Does it induce the development of ectopic synapses with granule cell dendrites?
    • Represa A, Jorquera I, Le Gal La Salle G, Ben-Ari Y. 1993. Epilepsy induced collateral sprouting of hippocampal mossy fibers: does it induce the development of ectopic synapses with granule cell dendrites? Hippocampus 3:257-268.
    • (1993) Hippocampus , vol.3 , pp. 257-268
    • Represa, A.1    Jorquera, I.2    Le Gal La Salle, G.3    Ben-Ari, Y.4
  • 69
    • 0020406501 scopus 로고
    • A preferential loss of GABAergic, symmetric synapses in epileptic foci: A quantitative ultrastructural analysis of monkey neocortex
    • Ribak CE, Bradburne RM, Harris AB. 1982. A preferential loss of GABAergic, symmetric synapses in epileptic foci: a quantitative ultrastructural analysis of monkey neocortex. J Neurosci 2:1725-1735.
    • (1982) J Neurosci , vol.2 , pp. 1725-1735
    • Ribak, C.E.1    Bradburne, R.M.2    Harris, A.B.3
  • 70
    • 0029143735 scopus 로고
    • Early changes in prodynorphin mRNA and ir-dynorphin A levels after kindled seizures in the rat
    • Romualdi P, Donatini A, Bregola G, Beani L, Ferri S, Simonato M. 1995. Early changes in prodynorphin mRNA and ir-dynorphin A levels after kindled seizures in the rat. Eur J Neurosci 7:1850-1856.
    • (1995) Eur J Neurosci , vol.7 , pp. 1850-1856
    • Romualdi, P.1    Donatini, A.2    Bregola, G.3    Beani, L.4    Ferri, S.5    Simonato, M.6
  • 71
    • 0028879590 scopus 로고
    • A comparison of the role of dynorphin in the hippocampal mossy fiber pathway in guinea pig and rat
    • Salin PA, Weisskopf MG, Nicoll RA. 1995. A comparison of the role of dynorphin in the hippocampal mossy fiber pathway in guinea pig and rat. J Neurosci 15:6939-6945.
    • (1995) J Neurosci , vol.15 , pp. 6939-6945
    • Salin, P.A.1    Weisskopf, M.G.2    Nicoll, R.A.3
  • 72
    • 0025309305 scopus 로고
    • Spinules in axospinous synapses of the rat dentate gyrus: Changes in density following long-term potentiation
    • Schuster T, Krug M, Wenzel J. 1990. Spinules in axospinous synapses of the rat dentate gyrus: changes in density following long-term potentiation. Brain Res 523:171-174.
    • (1990) Brain Res , vol.523 , pp. 171-174
    • Schuster, T.1    Krug, M.2    Wenzel, J.3
  • 73
    • 0029066434 scopus 로고
    • Postnatal development and synaptic connections of hilar mossy cells in the hippocampal dentate gyrus in rhesus monkeys
    • Seress L, Ribak CE. 1995a. Postnatal development and synaptic connections of hilar mossy cells in the hippocampal dentate gyrus in rhesus monkeys. J Comp Neural 355:93-110.
    • (1995) J Comp Neural , vol.355 , pp. 93-110
    • Seress, L.1    Ribak, C.E.2
  • 74
    • 0029119311 scopus 로고
    • Postnatal development of CA3 pyramidal neurons and their afferents in the Ammon's horn of rhesus monkeys
    • Seress L, Ribak CE. 1995b. Postnatal development of CA3 pyramidal neurons and their afferents in the Ammon's horn of rhesus monkeys. Hippocampus 5:217-231.
    • (1995) Hippocampus , vol.5 , pp. 217-231
    • Seress, L.1    Ribak, C.E.2
  • 75
    • 0030339216 scopus 로고    scopus 로고
    • Endogenous opioid regulation of hippocampal function
    • Simmons ML, Chavkin C. 1996. Endogenous opioid regulation of hippocampal function. Int Rev Neurobiol 39:145-196.
    • (1996) Int Rev Neurobiol , vol.39 , pp. 145-196
    • Simmons, M.L.1    Chavkin, C.2
  • 76
    • 0030799292 scopus 로고    scopus 로고
    • Spontaneous excitatory currents and κ-opioid receptor inhibition in dentate gyrus are increased in the rat pilocarpine model of temporal lobe epilepsy
    • Simmons ML, Terman GW, Chavkin C. 1998. Spontaneous excitatory currents and κ-opioid receptor inhibition in dentate gyrus are increased in the rat pilocarpine model of temporal lobe epilepsy. J Neurophysiol 78:1860-1868.
    • (1998) J Neurophysiol , vol.78 , pp. 1860-1868
    • Simmons, M.L.1    Terman, G.W.2    Chavkin, C.3
  • 78
    • 0026594823 scopus 로고
    • Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats
    • Sloviter RS. 1992. Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats. Neurosci Lett 137:91-96.
    • (1992) Neurosci Lett , vol.137 , pp. 91-96
    • Sloviter, R.S.1
  • 79
    • 0029018486 scopus 로고
    • Tonic inhibition originates from synapses close to the soma
    • Soltesz I, Smetters DK, Mody I. 1995. Tonic inhibition originates from synapses close to the soma. Neuron 14:1273-1283.
    • (1995) Neuron , vol.14 , pp. 1273-1283
    • Soltesz, I.1    Smetters, D.K.2    Mody, I.3
  • 80
    • 34250548773 scopus 로고
    • Erkrankung des ammonshorns als aetiologisches moment der epilepsie
    • Sommer W. 1880. Erkrankung des Ammonshorns als aetiologisches moment der epilepsie. Arch Psychiatr Nervenkr 10:631-675.
    • (1880) Arch Psychiatr Nervenkr , vol.10 , pp. 631-675
    • Sommer, W.1
  • 82
    • 0023872014 scopus 로고
    • Synaptic reorganization in the hippocampus induced by abnormal functional activity
    • Sutula T, Xiao-Xian H, Cavazos J, Scott G. 1988. Synaptic reorganization in the hippocampus induced by abnormal functional activity. Science 239:1147-1150.
    • (1988) Science , vol.239 , pp. 1147-1150
    • Sutula, T.1    Xiao-Xian, H.2    Cavazos, J.3    Scott, G.4
  • 83
    • 0024444281 scopus 로고
    • Mossy fiber synaptic reorganization in the epileptic human temporal lobe
    • Sutula T, Cascino G, Cavazos J, Parada I, Ramirez L. 1989. Mossy fiber synaptic reorganization in the epileptic human temporal lobe. Ann Neurol 26:321-330.
    • (1989) Ann Neurol , vol.26 , pp. 321-330
    • Sutula, T.1    Cascino, G.2    Cavazos, J.3    Parada, I.4    Ramirez, L.5
  • 84
    • 0027034173 scopus 로고
    • Assessing the functional significance of mossy fiber sprouting
    • Sutula TP, Golarai G, Cavazos J. 1992. Assessing the functional significance of mossy fiber sprouting. Epilepsy Res Suppl 7:251-259.
    • (1992) Epilepsy Res Suppl , vol.7 , pp. 251-259
    • Sutula, T.P.1    Golarai, G.2    Cavazos, J.3
  • 85
    • 0031984185 scopus 로고    scopus 로고
    • Synaptic and axonal remodeling of mossy fibers in the hilus and supragranular region of the dentate gyrus in kainate-treated rats
    • Sutula T, Zhang P, Lynch M, Sayin U, Golarai G, Rod R. 1998. Synaptic and axonal remodeling of mossy fibers in the hilus and supragranular region of the dentate gyrus in kainate-treated rats. J Comp Neurol 390:578-5949.
    • (1998) J Comp Neurol , vol.390 , pp. 578-5949
    • Sutula, T.1    Zhang, P.2    Lynch, M.3    Sayin, U.4    Golarai, G.5    Rod, R.6
  • 86
    • 0017716690 scopus 로고
    • The synaptic spinule in the dendritic spine: Electron microscopic study of the hippocampal dentate gyrus
    • Tarrant SB, Routtenberg A. 1977. The synaptic spinule in the dendritic spine: electron microscopic study of the hippocampal dentate gyrus. Tissue Cell 9:461-473.
    • (1977) Tissue Cell , vol.9 , pp. 461-473
    • Tarrant, S.B.1    Routtenberg, A.2
  • 87
    • 0021917797 scopus 로고
    • Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats
    • Tauck DL, Nadler JV. 1985. Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats. J Neurosci 5:1016-1022.
    • (1985) J Neurosci , vol.5 , pp. 1016-1022
    • Tauck, D.L.1    Nadler, J.V.2
  • 89
    • 0025330227 scopus 로고
    • Exocytosis from neuronal large dense-cored vesicles
    • Thureson-Klein ÅK, Klein RL. 1990. Exocytosis from neuronal large dense-cored vesicles. Int Rev Cytol 121:67-126.
    • (1990) Int Rev Cytol , vol.121 , pp. 67-126
    • Thureson-Klein, Å.K.1    Klein, R.L.2
  • 90
    • 0023783659 scopus 로고
    • Endogenous opioid peptides and epilepsy: Quieting the seizing brain?
    • Tortella FC. 1988. Endogenous opioid peptides and epilepsy: quieting the seizing brain? Trends Pharmacol Sci 9:366-372.
    • (1988) Trends Pharmacol Sci , vol.9 , pp. 366-372
    • Tortella, F.C.1
  • 91
    • 0022651935 scopus 로고
    • U50,488, a highly selective kappa opioid: Anticonvulsant profile in rats
    • Tortella FC, Robles L, Holaday JW. 1985. U50,488, a highly selective kappa opioid: anticonvulsant profile in rats. J Pharmacol Exp Ther 237:49-53.
    • (1985) J Pharmacol Exp Ther , vol.237 , pp. 49-53
    • Tortella, F.C.1    Robles, L.2    Holaday, J.W.3
  • 92
    • 0028040022 scopus 로고
    • Dynorphin-immunoreactive terminals in the rat nucleus accumbens: Cellular sites for modulation of target neurons and interactions with catecholamine afferents
    • Van Bockstaele EJ, Sesack SR, Pickel VM. 1994. Dynorphin-immunoreactive terminals in the rat nucleus accumbens: cellular sites for modulation of target neurons and interactions with catecholamine afferents. J Comp Neurol 341:1-15.
    • (1994) J Comp Neurol , vol.341 , pp. 1-15
    • Van Bockstaele, E.J.1    Sesack, S.R.2    Pickel, V.M.3
  • 93
    • 0023039541 scopus 로고
    • Morphogenesis of the mossy fiber synapses in the hippocampus of the rhesus monkey
    • Vijayan VK. 1986. Morphogenesis of the mossy fiber synapses in the hippocampus of the rhesus monkey. Dev Brain Res 25:259-270.
    • (1986) Dev Brain Res , vol.25 , pp. 259-270
    • Vijayan, V.K.1
  • 95
    • 0027215626 scopus 로고
    • Endogenous dynorphins inhibit excitatory neurotransmission and block LTP induction in the hippocampus
    • Wagner JJ, Terman GW, Chavkin C. 1993. Endogenous dynorphins inhibit excitatory neurotransmission and block LTP induction in the hippocampus. Nature 363:451-454.
    • (1993) Nature , vol.363 , pp. 451-454
    • Wagner, J.J.1    Terman, G.W.2    Chavkin, C.3
  • 96
    • 0027447711 scopus 로고
    • The opioid peptide dynorphin mediates heterosynaptic depression of hippocampal mossy fibre synapses and modulates long-term potentiation
    • Weisskopf MG, Zalutsky RA, Nicoll RA. 1993. The opioid peptide dynorphin mediates heterosynaptic depression of hippocampal mossy fibre synapses and modulates long-term potentiation. Nature 362:423-427.
    • (1993) Nature , vol.362 , pp. 423-427
    • Weisskopf, M.G.1    Zalutsky, R.A.2    Nicoll, R.A.3
  • 97
    • 0028834425 scopus 로고
    • Depth electrode studies and intracellular dentate granule cell recordings in temporal lobe epilepsy
    • Williamson A, Spencer SS, Spencer DD. 1995. Depth electrode studies and intracellular dentate granule cell recordings in temporal lobe epilepsy. Ann Neurol 38:778-787.
    • (1995) Ann Neurol , vol.38 , pp. 778-787
    • Williamson, A.1    Spencer, S.S.2    Spencer, D.D.3
  • 98
    • 0029937283 scopus 로고    scopus 로고
    • Electrographic seizures and new recurrent excitatory circuits in the dentate gyrus of hippocampal slices from kainate-treated epileptic rats
    • Wuarin J-P, Dudek FE. 1996. Electrographic seizures and new recurrent excitatory circuits in the dentate gyrus of hippocampal slices from kainate-treated epileptic rats. J Neurosci 16:4438-4448.
    • (1996) J Neurosci , vol.16 , pp. 4438-4448
    • Wuarin, J.-P.1    Dudek, F.E.2
  • 99
    • 0344608966 scopus 로고
    • Dynorphin immunoreactivity in the dentate gyrus in human temporal lobe epilepsy: An electron microscopic study of reorganized mossy fiber synapses
    • Zhang N, Houser CR. 1995. Dynorphin immunoreactivity in the dentate gyrus in human temporal lobe epilepsy: an electron microscopic study of reorganized mossy fiber synapses. Soc Neurosci Abstr 21:1962.
    • (1995) Soc Neurosci Abstr , vol.21 , pp. 1962
    • Zhang, N.1    Houser, C.R.2
  • 100
    • 0025085803 scopus 로고
    • Aspartate-like and glutamate-like immunoreactivities in the inferior olive and climbing fibre system: A light microscopic and semiquantitative electron microscopic study in rat and baboon (Papio anubis)
    • Zhang N, Walberg F, Laake JH, Meldrum BS, Ottersen OP. 1990. Aspartate-like and glutamate-like immunoreactivities in the inferior olive and climbing fibre system: a light microscopic and semiquantitative electron microscopic study in rat and baboon (Papio anubis). Neuroscience 38:61-80.
    • (1990) Neuroscience , vol.38 , pp. 61-80
    • Zhang, N.1    Walberg, F.2    Laake, J.H.3    Meldrum, B.S.4    Ottersen, O.P.5
  • 101
    • 0030805667 scopus 로고    scopus 로고
    • Potentiation of NMDA receptor-mediated responses by dynorphin at low extracellular glycine concentrations
    • Zhang L, Peoples RW, Oz M, Harvey-White J, Weight FF, Brauneis U. 1997. Potentiation of NMDA receptor-mediated responses by dynorphin at low extracellular glycine concentrations. J Neurophysiol 78:582-590.
    • (1997) J Neurophysiol , vol.78 , pp. 582-590
    • Zhang, L.1    Peoples, R.W.2    Oz, M.3    Harvey-White, J.4    Weight, F.F.5    Brauneis, U.6
  • 102
    • 0022535502 scopus 로고
    • Exocytosis from large dense cored vesicles outside the active synaptic zones of terminals within the trigeminal subnucleus caudalis: A possible mechanism for neuropeptide release
    • Zhu PC, Thureson-Klein ÅK, Klein RL. 1986. Exocytosis from large dense cored vesicles outside the active synaptic zones of terminals within the trigeminal subnucleus caudalis: a possible mechanism for neuropeptide release. Neuroscience 19:43-54.
    • (1986) Neuroscience , vol.19 , pp. 43-54
    • Zhu, P.C.1    Thureson-Klein, Å.K.2    Klein, R.L.3


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