-
1
-
-
34250016249
-
Hepatocyte-Specific IKKgamma/NEMO Expression Determines the Degree of Liver Injury
-
DOI 10.1053/j.gastro.2007.03.045, PII S0016508507005732
-
Beraza N, Ludde T, Assmus U, et al. Hepatocyte-specific IKK gamma/NEMO expression determines the degree of liver injury. Gastroenterology 2007;132:2504-17. (Pubitemid 46890863)
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2504-2517
-
-
Beraza, N.1
Ludde, T.2
Assmus, U.3
Roskams, T.4
Borght, S.V.5
Trautwein, C.6
-
2
-
-
68149171396
-
Hepatocyte-specific NEMO deletion promotes NK/NKT cell- And TRAIL-dependent liver damage
-
Beraza N, Malato Y, Sander LE, et al. Hepatocyte-specific NEMO deletion promotes NK/NKT cell- and TRAIL-dependent liver damage. J Exp Med 2009;206:1727-37.
-
(2009)
J Exp Med
, vol.206
, pp. 1727-1737
-
-
Beraza, N.1
Malato, Y.2
Sander, L.E.3
-
3
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
DOI 10.1038/nature04870, PII NATURE04870
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006;441:431-6. (Pubitemid 44050137)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 431-436
-
-
Karin, M.1
-
4
-
-
46249095271
-
Hepatocyte-specific inhibitor-of-kappaB-kinase deletion triggers the innate immune response and promotes earlier cell proliferation during liver regeneration
-
DOI 10.1002/hep.22264
-
Malato Y, Sander LE, Liedtke C, et al. Hepatocyte-specific inhibitor-of-kappaB-kinase deletion triggers the innate immune response and promotes earlier cell proliferation during liver regeneration. Hepatology 2008;47:2036-50. (Pubitemid 351945570)
-
(2008)
Hepatology
, vol.47
, Issue.6
, pp. 2036-2050
-
-
Malato, Y.1
Sander, L.E.2
Liedtke, C.3
Al-Masaoudi, M.4
Tacke, F.5
Trautwein, C.6
Beraza, N.7
-
5
-
-
33846839443
-
Deletion of NEMO/IKKgamma in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma
-
DOI 10.1016/j.ccr.2006.12.016, PII S1535610807000207
-
Luedde T, Beraza N, Kotsikoris V, et al. Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 2007;11:119-32. (Pubitemid 46209851)
-
(2007)
Cancer Cell
, vol.11
, Issue.2
, pp. 119-132
-
-
Luedde, T.1
Beraza, N.2
Kotsikoris, V.3
Van, L.G.4
Nenci, A.5
De, V.R.6
Roskams, T.7
Trautwein, C.8
Pasparakis, M.9
-
6
-
-
68049131203
-
New molecular insights into the mechanisms of cholestasis
-
Wagner M, Zollner G, Trauner M. New molecular insights into the mechanisms of cholestasis. J Hepatol 2009;51:565-80.
-
(2009)
J Hepatol
, vol.51
, pp. 565-580
-
-
Wagner, M.1
Zollner, G.2
Trauner, M.3
-
9
-
-
0037404039
-
Bile acid regulation of hepatic physiology: IV. Bile acids and death receptors
-
Higuchi H, Gores GJ. Bile acid regulation of hepatic physiology: IV. Bile acids and death receptors. Am J Physiol Gastrointest Liver Physiol 2003;284:G734-8.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Higuchi, H.1
Gores, G.J.2
-
10
-
-
0035914341
-
The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis
-
Higuchi H, Bronk SF, Takikawa Y, et al. The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis. J Biol Chem 2001;276:38610-18.
-
(2001)
J Biol Chem
, vol.276
, pp. 38610-38618
-
-
Higuchi, H.1
Bronk, S.F.2
Takikawa, Y.3
-
11
-
-
0036827808
-
Cholestasis increases tumor necrosis factor-related apoptotis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to trail-mediated cytotoxicity
-
DOI 10.1124/jpet.102.040030
-
Higuchi H, Bronk SF, Taniai M, et al. Cholestasis increases tumor necrosis factor-related apoptotis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity. J Pharmacol Exp Ther 2002;303:461-7. (Pubitemid 35231214)
-
(2002)
Journal of Pharmacology and Experimental Therapeutics
, vol.303
, Issue.2
, pp. 461-467
-
-
Higuchi, H.1
Bronk, S.F.2
Taniai, M.3
Canbay, A.4
Gores, G.J.5
-
12
-
-
0346422479
-
Bile Acids Up-regulate Death Receptor 5/TRAIL-receptor 2 Expression via a c-Jun N-terminal Kinase-dependent Pathway Involving Sp1
-
DOI 10.1074/jbc.M309476200
-
Higuchi H, Grambihler A, Canbay A, et al. Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1. J Biol Chem 2004;279:51-60. (Pubitemid 38044798)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.1
, pp. 51-60
-
-
Higuchi, H.1
Grambihler, A.2
Canbay, A.3
Bronk, S.F.4
Gores, G.J.5
-
13
-
-
34547193134
-
Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity
-
DOI 10.1136/gut.2006.118059
-
Malhi H, Barreyro FJ, Isomoto H, et al. Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity. Gut 2007;56:1124-31. (Pubitemid 47123245)
-
(2007)
Gut
, vol.56
, Issue.8
, pp. 1124-1131
-
-
Malhi, H.1
Barreyro, F.J.2
Isomoto, H.3
Bronk, S.F.4
Gores, G.J.5
-
14
-
-
32044467118
-
24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice
-
DOI 10.1053/j.gastro.2005.10.018, PII S0016508505021748
-
Fickert P, Wagner M, Marschall HU, et al. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology 2006;130:465-81. (Pubitemid 43202044)
-
(2006)
Gastroenterology
, vol.130
, Issue.2
, pp. 465-481
-
-
Fickert, P.1
Wagner, M.2
Marschall, H.-U.3
Fuchsbichler, A.4
Zollner, G.5
Tsybrovskyy, O.6
Zatloukal, K.7
Liu, J.8
Waalkes, M.P.9
Cover, C.10
Denk, H.11
Hofmann, A.F.12
Jaeschke, H.13
Trauner, M.14
-
15
-
-
0036788262
-
Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles
-
Fickert P, Zollner G, Fuchsbichler A, et al. Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles. Gastroenterology 2002;123:1238-51.
-
(2002)
Gastroenterology
, vol.123
, pp. 1238-1251
-
-
Fickert, P.1
Zollner, G.2
Fuchsbichler, A.3
-
16
-
-
29144535372
-
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
-
Dai M, Wang P, Boyd AD, et al. Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res 2005;33:-175.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 175
-
-
Dai, M.1
Wang, P.2
Boyd, A.D.3
-
17
-
-
33845985335
-
SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer- Binding protein alpha transcriptional complex
-
DOI 10.1074/jbc.M607215200
-
Qiao L, Shao J. SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein alpha transcriptional complex. J Biol Chem 2006;281:39915-24. (Pubitemid 46041795)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.52
, pp. 39915-39924
-
-
Qiao, L.1
Shao, J.2
-
18
-
-
57749116021
-
A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding
-
Hirota K, Sakamaki J, Ishida J, et al. A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding. J Biol Chem 2008;283:32432-41.
-
(2008)
J Biol Chem
, vol.283
, pp. 32432-32441
-
-
Hirota, K.1
Sakamaki, J.2
Ishida, J.3
-
19
-
-
0028933933
-
Ursodeoxycholic acid therapy of chronic cholestatic conditions in adults and children
-
Poupon R, Poupon RE. Ursodeoxycholic acid therapy of chronic cholestatic conditions in adults and children. Pharmacol Ther 1995;66:1-15.
-
(1995)
Pharmacol Ther
, vol.66
, pp. 1-15
-
-
Poupon, R.1
Poupon, R.E.2
-
20
-
-
0031733596
-
Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases
-
DOI 10.1007/s004410051181
-
Heid HW, Moll R, Schwetlick I, et al. Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases. Cell Tissue Res 1998;294:309-21. (Pubitemid 28486407)
-
(1998)
Cell and Tissue Research
, vol.294
, Issue.2
, pp. 309-321
-
-
Heid, H.W.1
Moll, R.2
Schwetlick, I.3
Rackwitz, H.-R.4
Keenan, T.W.5
-
21
-
-
1242336980
-
Apoptosis: The Nexus of Liver Injury and Fibrosis
-
DOI 10.1002/hep.20051
-
Canbay A, Friedman S, Gores GJ. Apoptosis: the nexus of liver injury and fibrosis. Hepatology 2004;39:273-8. (Pubitemid 38222163)
-
(2004)
Hepatology
, vol.39
, Issue.2
, pp. 273-278
-
-
Canbay, A.1
Friedman, S.2
Gores, G.J.3
-
22
-
-
33847011377
-
Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration
-
DOI 10.1016/j.bbamcr.2006.04.014, PII S0167488906000978
-
Geier A, Wagner M, Dietrich CG, et al. Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration. Biochim Biophys Acta 2007;1773:283-308. (Pubitemid 46275063)
-
(2007)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1773
, Issue.3
, pp. 283-308
-
-
Geier, A.1
Wagner, M.2
Dietrich, C.G.3
Trauner, M.4
-
23
-
-
33645738747
-
Endocrine functions of bile acids
-
Houten SM, Watanabe M, Auwerx J. Endocrine functions of bile acids. EMBO J 2006;25:1419-25.
-
(2006)
EMBO J
, vol.25
, pp. 1419-1425
-
-
Houten, S.M.1
Watanabe, M.2
Auwerx, J.3
-
24
-
-
0031770301
-
Ursodeoxycholic acid in cholestasis: Potential mechanisms of action and therapeutic applications
-
Beuers U, Boyer JL, Paumgartner G. Ursodeoxycholic acid in cholestasis: potential mechanisms of action and therapeutic applications. Hepatology 1998;28:1449-53. (Pubitemid 28549111)
-
(1998)
Hepatology
, vol.28
, Issue.6
, pp. 1449-1453
-
-
Beuers, U.1
Boyer, J.L.2
Paumgartner, G.3
-
25
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
DOI 10.1126/science.1128294
-
Ozcan U, Yilmaz E, Ozcan L, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 2006;313:1137-40. (Pubitemid 44300242)
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
26
-
-
34547411540
-
Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver
-
DOI 10.1002/hep.21632
-
Huang J, Iqbal J, Saha PK, et al. Molecular characterization of the role of orphan receptor small heterodimer partner in development of fatty liver. Hepatology 2007;46:147-57. (Pubitemid 47171931)
-
(2007)
Hepatology
, vol.46
, Issue.1
, pp. 147-157
-
-
Huang, J.1
Iqbal, J.2
Saha, P.K.3
Liu, J.4
Chan, L.5
Hussain, M.M.6
Moore, D.D.7
Wang, L.8
-
27
-
-
0031160517
-
Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAT) gene in liver
-
Keppler D, Konig J. Hepatic canalicular membrane 5: expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAT) gene in liver. FASEB J 1997;11:509-16. (Pubitemid 27274424)
-
(1997)
FASEB Journal
, vol.11
, Issue.7
, pp. 509-516
-
-
Keppler, D.1
Konig, J.2
-
28
-
-
0037379362
-
Bile salt transporters: Molecular characterization, function, and regulation
-
Trauner M, Boyer JL. Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev 2003;83:633-71. (Pubitemid 36378680)
-
(2003)
Physiological Reviews
, vol.83
, Issue.2
, pp. 633-671
-
-
Trauner, M.1
Boyer, J.L.2
-
29
-
-
0344927562
-
Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
-
Konig J, Nies AT, Cui Y, et al. Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance. Biochim Biophys Acta 1999;1461:377-94.
-
(1999)
Biochim Biophys Acta
, vol.1461
, pp. 377-394
-
-
Konig, J.1
Nies, A.T.2
Cui, Y.3
|