Synthesis and antileishmanial activity of 5-(5-nitroaryl)-2-substituted- thio-1,3,4-thiadiazoles

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 26, Issue 1, 2011, Pages 123-128

  Alipour, Eskandar ^a   Emami, Saeed ^b   Yahya Meymandi, Azadeh ^c   Nakhjiri, Maryam ^c   Johari, Farnaz ^a   Ardestani, Sussan K ^d   Poorrajab, Fatemeh ^d   Hosseini, Maryam ^a   Shafiee, Abbas ^c   Foroumadi, Alireza ^e  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d UNIVERSITY OF TEHRAN   (Iran)

^e TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

1,3,4 Thiadiazole; 5 Nitrohetrocycles; leishmania major; leishmaniasis

Indexed keywords

1 (2 CHLOROPHENYL) 2 [5 (1 METHYL 5 NITRO 1H IMIDAZOL 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO]ETHANONE; 1 (2 CHLOROPHENYL) 2 [5 (5 NITROFURAN 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO]ETHANONE; 1 (2 CHLOROPHENYL) 2 [5 (5 NITROTHIOPHEN 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO]ETHANONE; 1 (3 CHLOROPHENYL) 2 [5 (1 METHYL 5 NITRO 1H IMIDAZOL 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO]ETHANONE; 1 (3 CHLOROPHENYL) 2 [5 (5 NITROFURAN 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO]ETHANONE; 1 (3 CHLOROPHENYL) 2 [5 (5 NITROTHIOPHEN 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO]ETHANONE; 1 (4 CHLOROPHENYL) 2 [5 (1 METHYL 5 NITRO 1H IMIDAZOL 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO]ETHANONE; 1 (4 CHLOROPHENYL) 2 [5 (5 NITROFURAN 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO]ETHANONE; 1 (4 CHLOROPHENYL) 2 [5 (5 NITROTHIOPHEN 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO]ETHANONE; 2 (5 NITROFURAN 2 YL) 5 (1 PHENYLETHYLTHIO) 1,3,4 THIADIAZOLE; 2 (5 NITROTHIOPHEN 2 YL) 5 (1 PHENYLETHYLTHIO) 1,3,4 THIADIAZOLE; 2 [5 (5 NITROFURAN 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO] 1 PHENYLPROPAN 1 ONE; 2 [5 (5 NITROTHIOPHEN 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO] 1 PHENYLPROPAN 1 ONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 [5 (5 NITROFURAN 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO] 1 PHENYLPROPAN 1 ONE; 3 [5 (5 NITROTHIOPHEN 2 YL) 1,3,4 THIADIAZOL 2 YLTHIO] 1 PHENYLPROPAN 1 ONE; 5 (5 NITROARYL) 2 SUBSTITUTED THIO 1,3,4 THIADIAZOLE; ANTILEISHMANIAL AGENT; UNCLASSIFIED DRUG;

ANTILEISHMANIAL ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; COLORIMETRY; DRUG SCREENING; DRUG SYNTHESIS; IC 50; LEISHMANIA MAJOR; NONHUMAN; PRIORITY JOURNAL; PROMASTIGOTE; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY;

ANTIPROTOZOAL AGENTS; CELL CULTURE TECHNIQUES; HUMANS; INHIBITORY CONCENTRATION 50; LEISHMANIA MAJOR; LEISHMANIASIS; NITRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLIUM SALTS; THIADIAZOLES; THIAZOLES;

LEISHMANIA MAJOR;

EID: 79851483780     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756361003733654     Document Type: Article

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