Synthesis and leishmanicidal activity of 2,3,4-substituted-5-imidazolones

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 25, Issue 1, 2010, Pages 29-37

  Khan, Khalid Mohammed ^a   Mughal, Uzma Rasool ^a   Ambreen, Nida ^a   Samreen, ^a   Perveen, Shahnaz ^b   Choudhary, M Iqbal ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

^b PCSIR LABORATORIES COMPLEX   (Pakistan)

Author keywords

Imidazolone; Leishmania major; Leishmanicidal activity; Substitution effect

Indexed keywords

2 METHYL 3 PHENYL 5 [2 THIENYLMETHYLIDENE] 3,5 DIHYDRO 4H IMIDAZOL 4 ONE; 2 METHYL 3 PHENYL 5 [PHENYLMETHYLIDENE] 3,5 DIHYDIDRO 4H MIDAZOLE 4 ONE; 2,3 DIPHENYL 5 [PHENYLMETHYLIDENE] 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; 3 (2 METHOXYPHENYL) 2 METHYL 5 [2 THIENYLMETHYLIDENE] 3,5 DIHYDRO 4H IMIDAZOL 4 ONE; 3 (3 METHOXYPHENYL) 2 METHYL 5 [2 THIENYLMETHYLIDENE] 3,5 DIHYDRO 4H IMIDAZOL 4 ONE; 3 (3 METHOXYPHENYL) 2 PHENYL 5 [ 2 THIENYLMETHYLIDENE 3,5 DIHYDRO 4H IMIDAZOL 4 ONE; 3 (4 METHOXYPHENYL) 2 METHYL 5 [2 THIENYLMETHYLIDENE] 3,5 DIHYDRO 4H IMIDAZOL 4 ONE; 3 (4 METHOXYPHENYL) 2 PHENYL 5 [2 THIENYLMETHYLIDENE 3,5 DIHYDRO 4H IMIDAZOL 4 ONE; 3 (5 METHOXYPHENYL) 2 METHYL 5 [2 THIENYLMETHYLIDENE] 3,5 DIHYDRO 4H IMIDAZOL 4 ONE; 5 [(1,1' BIPHENYL) 4 YLMETHYLIDENE] 2,3 DIPHENYLIDENE 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; 5 [(1,1' BIPHENYL) 4 YLMETHYLIDENE] 3 (3 METHOXYPHENYL) 2 METHYL 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; 5 [(1,1' BIPHENYL)4 YLMETHYLIDENE] 3(3 METHOXYPHEYNYL) 2 PHENYL 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; 5 [(1,1' BIPHENYL)4 YLMETHYLIDENE] 3(4 METHOXYPHEYNYL) 2 PHENYL 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; 5 [(1,1' BIPHENYL] 4 YLMETHYLIDENE] 3 (2 METHOXYPHENYL 2 PHENYL 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; 5 [(1,1' DIPHENYL) 4 YLMETHYLIDENE] 2 METHYL 3 PHENYL 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; 5 [(2 CHLORO 5 NITROPHENYL)METHYLIDENE] 3 (4 METHOXYPHENYL)2 PHENYL 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; 5 [(4 FLUOROPHENYL)METHYLIDENE] 2 METHYL 3 PHENYL 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; 5 [(4 FLUOROPHENYL)METHYLIDENE] 3 (2 METHOXYPHENYL)2 METHYL 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; 5 [(4 FLUOROPHENYL)METHYLIDENE] 3 (3 METHOXYPHENYL)2 METHYL 3,5 DIHYDRO 4H IMIDAZOLE 4 ONE; AMPHOTERICIN B; IMIDAZOLE DERIVATIVE; PENTAMIDINE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; LEISHMANIA; NONHUMAN; PRIORITY JOURNAL; STANDARD;

AMPHOTERICIN B; ANIMALS; ANTIPROTOZOAL AGENTS; IMIDAZOLES; LEISHMANIA; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

LEISHMANIA MAJOR;

EID: 74349124358     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756360902932768     Document Type: Article

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