Frequency of lactase persistence genotype in a healthy Polish population

Central European Journal of Biology

Volumn 6, Issue 2, 2011, Pages 176-179

  Płoszaj, Tomasz ^a   Jędrychowska Dańska, Krystyna ^a   Witas, Henryk W ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Hypolactasia; Lactase persistence; Lactose malabsorption; LCT 13910C > T genotype; Milk; Poland

Indexed keywords

MAMMALIA;

EID: 79651475165     PISSN: 1895104X     EISSN: 16443632     Source Type: Journal    
DOI: 10.2478/s11535-010-0114-1     Document Type: Article

References (28)

1. Lehtimäki T., Hemminki J., Rontu R., Mikkila V., Räsänen L., Laaksonen M., et al., The effects of adult-type hypolactasia on body height growth and dietary calcium intake from childhood into young adulthood: a 21-year follow-up study-the Cardiovascular Risk in Young Finns Study, Pediatrics, 2006, 118, 1553-1559.
2. Troelsen J. T., Adult-type hypolactasia and regulation of lactase expression, Biochim. Biophys. Acta, 2005, 1723, 19-32.
3. Laaksonen M. M., Mikkilä V., Räsänen L., Rontu R., Lehtimäki T. J., Viikari J. S., et al., Genetic lactase non-persistence, consumption of milk products and intakes of milk nutrients in Finns from childhood to young adulthood, Br. J. Nutr., 2009, 102, 8-17.
4. Laaksonen M. M., Impivaara O., Sievänen H., Viikari J. S., Lehtimäki T. J., Lamberg-Allardt C. J., et al., Associations of genetic lactase non-persistence and sex with bone loss in young adulthood, Bone, 2009, 44, 1003-1009.
5. Wang Y., Harvey C. B., Hollox E. J., Phillips A. D., Poulter M., Clay P., et al., The genetically programmed down-regulation of lactase in children, Gastroenterology, 1998, 114, 1230-1236.
6. Enattah N. S., Jensen T. G., Nielsen M., Lewinski R., Kuokkanen M., Rasinpera H., et al., Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture, Am. J. Hum. Genet., 2008, 82, 57-72.
7. Holden C., Mace R., Phylogenetic analysis of the evolution of lactose digestion in adults, Hum. Biol., 1997, 69, 605-628.
8. Enattah N. S., Trudeau A., Pimenoff V., Maiuri L., Auricchio S., Greco L., et al., Evidence of stillongoing convergence evolution of the lactase persistence T-13910 alleles in humans, Am. J. Hum. Genet., 2007, 81, 615-625.
9. Swallow D. M., Genetics of lactase persistence and lactose intolerance, Annu. Rev. Genet., 2003, 37, 197-219.
10. Enattah N. S., Sahi T., Savilahti E., Terwilliger J. D., Peltonen L., Järvelä I., Identification of a variant associated with adult-type hypolactasia, Nat. Genet., 2002, 30, 233-237.
11. Lehtimaki T., Hutri-Kahonen N., Kahonen M., Hemminki J., Mikkila V., Laaksonen M., et al., Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: the Cardiovascular Risk in Young Finns Study, Clin. Sci. (Lond.), 2008, 115, 265-271.
12. Lewinsky R. H., Jensen T. G., Moller J., Stensballe A., Olsen J., Troelsen J. T., T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro, Hum. Mol. Genet., 2005, 14, 3945-3953.
13. Troelsen J. T., Olsen J., Moller J., Sjostrom H., An upstream polymorphism associated with lactase persistence has increased enhancer activity, Gastroenterology, 2003, 125, 1686-1694.
14. Rasinpera H., Savilahti E., Enattah N. S., Kuokkanen M., Tötterman N., Lindahl H., et al., A genetic test which can be used to diagnose adult-type hypolactasia in children, Gut, 2004, 53, 1571-1576.
15. Ingram C. J., Mulcare C. A., Itan Y., Thomas M. G., Swallow D. M., Lactose digestion and the evolutionary genetics of lactase persistence, Hum. Genet., 2009, 124, 579-591.
16. Xu L., Sun H., Zhang X., Wang J., Sun D., Chen F., et al., The -22018A allele matches the lactase persistence phenotype in northern Chinese populations, Scand. J. Gastroenterol., 2010, 45, 168-174.
17. Imtiaz F., Savilahti E., Sarnesto A., Trabzuni D., Al-Kahtani K., Kagevi I., et al., The T/G 13915 variant upstream of the lactase gene (LCT) is the founder allele of lactase persistence in an urban Saudi population, J. Med. Genet., 2007, 44, e89.
18. Kettunen J., Silander K., Saarela O., Amin N., Muller M., Timpson N., et al., European lactase persistence genotype shows evidence of association with increase in body mass index, Hum. Mol. Genet., 2010, 19, 1129-1136.
19. Burger J., Kirchner M., Bramanti B., Haak W., Thomas M. G., Absence of the lactase-persistenceassociated allele in early Neolithic Europeans, Proc. Natl. Acad. Sci. USA, 2007, 104, 3736-3741.
20. Ksiazyk J., Flatz G., Socha J., Flatz S., Bak E., Wystepowanie objawów nietolerancji laktozy w świetle badań populacyjnych w Polsce (Incidence of lactose intolerance discerned in population studies in Poland), Wiad. Lek., 1985, 38, 183-187, (in Polish).
21. Tamura K., Dudley J., Nei M., Kumar S., MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4. 0, Mol. Biol. Evol., 2007, 24, 1596-1599.
22. Almon R., Patterson E., Nilsson T. K., Engfeldt P., Sjöström M., Body fat and dairy product intake in lactase persistent and non-persistent children and adolescents, Food Nutr. Res., 2010, 54, 5141.
23. Itan Y., Jones B. L., Ingram C. J., Swallow D. M., Thomas M. G., A worldwide correlation of lactase persistence phenotype and genotypes, BMC Evol. Biol., 2010, 10, 36.
24. Moskalik B., Wielicka A., Age influence on dairy products consumption habits, Rocz. AR Pozn., 2005, 4, 59-65.
25. Mulcare C. A., Weale M. E., Jones A. L., Connell B., Zeitlyn D., Tarekegn A., et al., The T allele of a single-nucleotide polymorphism 13. 9 kb upstream of the lactase gene (LCT) (C-13. 9kbT) does not predict or cause the lactase-persistence phenotype in Africans, Am. J. Hum. Genet., 2004, 74, 1102-1110.
26. Lember M., Torniainen S., Kull M., Kallikorm R., Saadla P., Rajasalu T., et al., Lactase nonpersistence and milk consumption in Estonia, World J. Gastroenterol., 2006, 12, 7329-7331.
27. Khabarova Y. A., Torniainen S. T., Nurmi H. A., Jävelä I. E., Isokoski M. K., Mattila K. J., Prevalence of lactase persistent/non-persistent genotypes and milk consumption in a young population in northwest Russia, World J. Gastroenterol., 2009, 15, 1849-1853.
28. Nagy D., Bogácsi-Szabó E., Várkonyi A., Csányi B., Czibula A., Bede O., et al., Prevalence of adult-type hypolactasia as diagnosed with genetic and lactose hydrogen breath tests in Hungarians, Eur. J. Clin. Nutr., 2009, 63, 909-912.