Prevalence of lactase persistent/non-persistent genotypes and milk consumption in a young population in north-west Russia

World Journal of Gastroenterology

Volumn 15, Issue 15, 2009, Pages 1849-1853

  Khabarova, Yulia ^a   Torniainen, Suvi ^b   Nurmi, Hanna ^b   Järvelä, Irma ^b   Isokoski, Mauri ^c   Mattila, Kari ^d,e  

^a NORTHERN STATE MEDICAL UNIVERSITY   (Russian Federation)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF TAMPERE   (Finland)

^d TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^e Centre of General Practice   (Finland)

Author keywords

C C 13910 genotype; Hypolactasia; Lactase persistence non persistence; Lactose malabsorption; Milk consumption; North west Russia

Indexed keywords

CYTOSINE; GUANINE; LACTASE; THYMINE;

ABDOMINAL DISCOMFORT; ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; ENZYME ACTIVITY; ETHNIC DIFFERENCE; GENOTYPE; HUMAN; LACTASE DEFICIENCY; LACTOSE TOLERANCE; MILK; POLYMERASE CHAIN REACTION; POPULATION GENETICS; RUSSIAN FEDERATION; SELF REPORT; SEQUENCE ANALYSIS;

ADOLESCENT; ADULT; ANIMALS; DIET; GENOTYPE; HUMANS; LACTASE; LACTOSE INTOLERANCE; MILK; QUESTIONNAIRES; RANDOM ALLOCATION; RUSSIA; YOUNG ADULT;

EID: 67651244893     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.15.1849     Document Type: Article

References (26)

1. Sahi T. Genetics and epidemiology of adult-type hypolactasia. Scand J Gastroenterol Suppl 1994; 202: 7-20
2. Isokoski M, Sahi T, Villako K, Tamm A. Epidemiology and genetics of lactose malabsorption. Ann Clin Res 1981; 13: 164-168
3. Sahi T, Isokoski M, Jussila J, Launiala K, Pyörälä K. Recessive inheritance of adult-type lactose malabsorption. Lancet 1973; 2: 823-826
4. Simoons FJ. Primary adult lactose intolerance and the milking habit: a problem in biologic and cultural interrelations. II. A culture historical hypothesis. Am J Dig Dis 1970; 15: 695-710
5. McCracken RD. Adult lactose tolerance. JAMA 1970; 213: 2257-2260
6. Flatz G. Genetics of lactose digestion in humans. Adv Hum Genet 1987; 16: 1-77
7. Arola H. Diagnosis of hypolactasia and lactose malabsorption. Scand J Gastroenterol Suppl 1994; 202: 26-35
8. Jussila J, Isokoski M, Launiala K. Prevalence of lactose malabsorption in a Finnish rural population. Scand J Gastroenterol 1970; 5: 49-56
9. Lewinsky RH, Jensen TG, Møller J, Stensballe A, Olsen J, Troelsen JT. T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro. Hum Mol Genet 2005; 14: 3945-3953
10. Rasinpera H. Adult-Type Hypolactasia: genotype-phenotype correlation [dissertation]. Helsinki Univ 2006. Available from: URL: http://ethesis.helsinki.fi
11. Järvelä IE. Molecular diagnosis of adult-type hypolactasia (lactase non-persistence). Scand J Clin Lab Invest 2005; 65: 535-539
12. Tishkoff SA, Reed FA, Ranciaro A, Voight BF, Babbitt CC, Silverman JS, Powell K, Mortensen HM, Hirbo JB, Osman M, Ibrahim M, Omar SA, Lema G, Nyambo TB, Ghori J, Bumpstead S, Pritchard JK, Wray GA, Deloukas P. Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet 2007; 39: 31-40
13. Imtiaz F, Savilahti E, Sarnesto A, Trabzuni D, Al-Kahtani K, Kagevi I, Rashed MS, Meyer BF, Järvelä I. The T/G 13915 variant upstream of the lactase gene (LCT) is the founder allele of lactase persistence in an urban Saudi population. J Med Genet 2007; 44: e89
14. Ingram CJ, Elamin MF, Mulcare CA, Weale ME, Tarekegn A, Raga TO, Bekele E, Elamin FM, Thomas MG, Bradman N, Swallow DM. A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence? Hum Genet 2007; 120: 779-788
15. Valenkevich LN. [Current problems of lactase deficiency] Vopr Pitan 1987; 31-34
16. Lember M, Tamm A, Villako K. Lactose-malabsorption in Estonians and russians. European Journal of Gastroenterology & Hepatology 1991, 3: 479-481
17. Kozlov AI. Hypolactasia in the indigenous populations of northern Russia. Int J Circumpolar Health 1998; 57: 18-21
18. Valenkevich LN, Iakhontova OI. [Lactase deficiency in aboriginal inhabitants of the Mordovian and Karelian ASSR] Klin Med (Mosk) 1989; 67: 56-58
19. Isokoski M, Tamm A, Sahi T, Tammur R, Lember M, Kuusk L, Reimand K, Arola H, Suurmaa K, Villako K. Prevalence of lactose malabsorption among Finno-Ugric nations and cultural historical hypothesis [abstract]. In: Abstracts. The World Congresses of Gastroenterology, 9th. 1990: PD 540
20. Zhvavyǐ NF, Kozlov AI, Kondik VM. [Lactase deficiency among representatives of various nationalities of Siberia] Vopr Pitan 1991; 32-35
21. Kozlov A. [Lactase intolerance (primary hypolactasia) in different population groups of Eurasia.] [Author's abstract of dissertation] Moscow Pedagogical State Univ 2004 (in Russian)
22. Borinskaia SA, Rebrikova DV, Nefedova VV, Kofiadi IA, Sokolova MV, Kolchina EV, Kulikova EA, Chernyshov VN, Kutsev SI, Polonikov AV, Ivanov VP, Kozlov AI, Iankovskiǐ NK. [Molecular diagnosis and frequencies of primary hypolactasia in populations of RUSSIA and neighboring countries] Mol Biol (Mosk) 2006; 40: 1031-1036
23. Lember M, Torniainen S, Kull M, Kallikorm R, Saadla P, Rajasalu T, Komu H, Jarvela I. Lactase non-persistence and milk consumption in Estonia. World J Gastroenterol 2006; 12: 7329-7331
24. Nilsson TK, Johansson CA. A novel method for diagnosis of adult hypolactasia by genotyping of the -13910 C/T polymorphism with Pyrosequencing technology. Scand J Gastroenterol 2004; 39: 287-290
25. Gudmand-Høyer E. The clinical significance of disaccharide maldigestion. Am J Clin Nutr 1994; 59: 735S-741S
26. Tamm A. Management of lactose intolerance. Scand J Gastroenterol Suppl 1994; 202: 55-63