Sparc is expressed in scars of the tenon's capsule and mediates scarring properties of human tenon's fibroblasts in vitro

Molecular Vision

Volumn 17, Issue , 2011, Pages 117-185

  Fuchshofer, Rudolf ^a   Kottler, Ulrike B ^b   Ohlmann, Anne V ^c   Schlötzer Schrehardt, Ursula ^b   Jünemann, Anselm ^b   Kruse, Friedrich E ^b   Ohlmann, Andreas ^a,b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; COLLAGEN; MESSENGER RNA; OSTEONECTIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2;

ARTICLE; BLOOD VESSEL WALL; CELL PROLIFERATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROBLAST; FILTERING OPERATION; GLAUCOMA SURGERY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SCAR; SCAR FORMATION; TENON CAPSULE; WESTERN BLOTTING; WOUND HEALING; ANIMAL; BIOSYNTHESIS; CHEMISTRY; GENE EXPRESSION REGULATION; GLAUCOMA; METABOLISM; METHODOLOGY; RAT;

ANIMALS; BROMODEOXYURIDINE; CELL PROLIFERATION; CICATRIX; COLLAGEN; EXTRACELLULAR MATRIX; FIBROBLASTS; GENE EXPRESSION REGULATION; GLAUCOMA; HUMANS; IMMUNOHISTOCHEMISTRY; OSTEONECTIN; RATS; TENON CAPSULE; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; WOUND HEALING;

EID: 79551715582     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 2006; 90:262-7. [PMID: 16488940]
2. Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RKII, Wilson MR, Gordon M, Ofor theOcular Hypertension Treatment Study Group.The Ocular Hypertension Treatment Study: A Randomized Trial Determines That Topical Ocular Hypotensive Medication Delays or Prevents the Onset of Primary Open-Angle Glaucoma. Arch Ophthalmol 2002 120 70-113 [PubMed: 12049574]
3. Khaw PT, Occleston NL, Schultz G, Grierson I, Sherwood MB, Larkin G. Activation and suppression of fibroblast function. Eye 1994; 8:188-95. [PMID: 7958020]
4. The Fluorouracil Filtering Surgery Study Group. Five-year follow-up of the Fluorouracil Filtering Surgery Study. Am J Ophthalmol 1996; 121:349-66. [PMID: 8604728]
5. Katz GJ, Higginbotham EJ, Lichter PR, Skuta GL, Musch DC, Bergstrom TJ, Johnson AT. Mitomycin C versus 5-fluorouracil in high-risk glaucoma filtering surgery. Extended follow-up. Ophthalmology 1995; 102:1263-9. [PMID: 9097762]
6. Yoon PS, Singh K. Update on antifibrotic use in glaucoma surgery, including use in trabeculectomy and glaucoma drainage implants and combined cataract and glaucoma surgery. Curr Opin Ophthalmol 2004; 15:141-6. [PMID: 15021227]
7. Daniels JT, Occleston NL, Crowston JG, Cordeiro MF, Alexander RA, Wilkins M, Porter R, Brown R, Khaw PT. Understanding and controlling the scarring response: The contribution of histology and microscopy. Microsc Res Tech 1998; 42:317-33. [PMID: 9766427]
8. Cordeiro MF, Bhattacharya SS, Schultz GS, Khaw PT. TGF- {beta}1, -{beta}2, and -{beta}3 In Vitro: Biphasic Effects on Tenon's Fibroblast Contraction, Proliferation, and Migration. Invest Ophthalmol Vis Sci 2000; 41:756-63. [PMID: 10711691]
9. Costa VP, Spaeth GL, Eiferman RA. S O-N. Wound healing modulation in glaucoma filtration surgery. Ophthalmic Surg 1993; 24:152-70. [PMID: 8483566]
10. Khaw PT, Chang L, Wong TTL, Mead A, Daniels JT, Cordeiro MF. Modulation of wound healing after glaucoma surgery. Curr Opin Ophthalmol 2001; 12:143-8. [PMID: 11224722]
11. Bornstein P, Sage EH. Matricellular proteins: extracellular modulators of cell function. Curr Opin Cell Biol 2002; 14:608-16. [PMID: 12231357]
12. Pichler RH, Hugo C, Shankland SJ, Reed MJ, Bassuk JA, Andoh TF, Lombardi DM, Schwartz SM, Bennett WM, Alpers CE, Sage EH, Johnson RJ, Couser WG. SPARC is expressed in renal interstitial fibrosis and in renal vascular injury. Kidney Int 1996; 50:1978-89. [PMID: 8943481]
13. Francki A, Sage EH. SPARC and the Kidney Glomerulus: Matricellular Proteins Exhibit Diverse Functions under Normal and Pathological Conditions. Trends Cardiovasc Med 2001; 11:32-7. [PMID: 11413050]
14. Chang W, Wei K, Jacobs SS, Upadhyay D, Weill D, Rosen GD. SPARC Suppresses Apoptosis of Idiopathic Pulmonary Fibrosis Fibroblasts through Constitutive Activation of Î2-Catenin. J Biol Chem 2010; 285:8196-206. [PMID: 20061390]
15. Frizell E, Liu SL, Abraham A, Ozaki I, Eghbali M, Sage EH, Zern MA. Expression of SPARC in normal and fibrotic livers. W.B. Saunders; 1995. p. 847-54.
16. Nakatani K, Seki S, Kawada N, Kitada T, Yamada T, Sakaguchi H, Kadoya H, Ikeda K, Kaneda K. Expression of SPARC by activated hepatic stellate cells and its correlation with the stages of fibrogenesis in human chronic hepatitis. Virchows Arch 2002; 441:466-74. [PMID: 12447677]
17. Berryhill BL, Kane B, Stramer B, Fini EM, Hassell JR. Increased SPARC accumulation during corneal repair. Exp Eye Res 2003; 77:85-92. [PMID: 12823991]
18. Mishima H, Hibino T, Hara H, Murakami J, Otori T. SPARC from corneal epithelial cells modulates collagen contraction by keratocytes. Invest Ophthalmol Vis Sci 1998; 39:2547-53. [PMID: 9856764]
19. Macko RF, Gelber AC, Young BA, Lowitt MH, White B, Wigley FM, Goldblum SE. Increased circulating concentrations of the counteradhesive proteins SPARC and thrombospondin-1 in systemic sclerosis (scleroderma). Relationship to platelet and endothelial cell activation. J Rheumatol 2002; 29:2565-70. [PMID: 12465153]
20. Zhou X, Tan FK, Reveille JD, Wallis D, Milewicz DM, Ahn C, Wang A, Arnett FC. Association of novel polymorphisms with the expression of SPARC in normal fibroblasts and with susceptibility to scleroderma. Arthritis Rheum 2002; 46:2990-9. [PMID: 12428242]
21. Strandjord TP, Madtes D, Weiss D, Sage E. Colla genaccumulation is decreased in SPARC-null mice with bleomycin-induced pulmonary fibrosis. Am J Physiol 1999; 277:L628-35. [PMID: 10484471]
22. Socha MJ, Manhiani M, Said N, Imig J, Motamed K. Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension. Am J Pathol 2007; 171:1104-12. [PMID: 17717147]
23. Wang J-C, Lai S, Guo X, Zhang X, de Crombrugghe B, Sonnylal S, Arnett F, Zhou X. Attenuation of fibrosis in vitro and in vivo with SPARC siRNA. Arthritis Res Ther 2010; 12:R60. [PMID: 20359365]
24. Camino AM, Atorrasagasti C, Maccio D, Prada F, Salvatierra E, Rizzo M, Alaniz L, Aquino JB, Podhajcer OL, Silva M, Mazzolini G. Adenovirus-mediated inhibition of SPARC attenuates liver fibrosis in rats. J Gene Med 2008; 10:993-1004. [PMID: 18615449]
25. Bradshaw AD, Reed MJ, Sage EH. SPARC-null Mice Exhibit Accelerated Cutaneous Wound Closure. J Histochem Cytochem 2002; 50:1-10. [PMID: 11748289]
26. Seet L-F, Su R, Barathi VA, Lee WS, Poh R, Heng YM, Manser E, Vithana EN, Aung T, Weaver M, Sage EH, Wong TT. SPARC Deficiency Results in Improved Surgical Survival in a Novel Mouse Model of Glaucoma Filtration Surgery. PLoS ONE 2010; 5:e9415.[PMID: 20195533]
27. Francki A, McClure TD, Brekken RA, Motamed K, Murri C, Wang T, Sage EH. SPARC regulates TGF-beta1-dependent signaling in primary glomerular mesangial cells. J Cell Biochem 2004; 91:915-25. [PMID: 15034927]
28. Schiemann BJ, Neil JR, Schiemann WP. SPARC Inhibits Epithelial Cell Proliferation in Part through Stimulation of the Transforming Growth Factor-{beta}-Signaling System. Mol Biol Cell 2003; 14:3977-88. [PMID: 14517312]
29. Kottler UB, Jünemann AGM, Aigner T, Zenkel M, Rummelt C, Schlötzer-Schrehardt U. Comparative effects of TGF-[beta]1 and TGF-[beta]2 on extracellular matrix production, proliferation, migration, and collagen contraction of human Tenon's capsule fibroblasts in pseudoexfoliation and primary open-angle glaucoma. Exp Eye Res 2005; 80:121-34. [PMID: 15652533]
30. Pena RA, Jerdan J, Glaser B. Effects of TGF-beta and TGF-beta neutralizing antibodies on fibroblast- induced collagen gel contraction: implications for proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci 1994; 35:2804-8. [PMID: 8188474]
31. Tripathi RC, Li J, Chalam KV, Tripathi BJ. Expression of Growth Factor mRNAs by Human Tenon's Capsule Fibroblasts. Exp Eye Res 1996; 63:339-46. [PMID: 8943707]
32. Jandeleit-Dahm K, Rumble J, Cox AJ, Kelly DJ, Dziadek M, Cooper ME, Gilbert RE. SPARC Gene Expression Is Increased in Diabetes-Related Mesenteric Vascular Hypertrophy. Microvasc Res 2000; 59:61-71. [PMID: 10625572]
33. Cordeiro MF. Role of transforming growth factor beta in conjunctival scarring. Clin Sci 2003; 104:181-7. [PMID: 12546640]
34. Schlötzer-Schrehardt U, Zenkel M, Küchle M, Sakai LY, Naumann GOH. Role of Transforming Growth Factor-[beta]1 and its Latent Form Binding Protein in Pseudoexfoliation Syndrome. Exp Eye Res 2001; 73:765-80. [PMID: 11846508]
35. Picht G, Welge-Luessen U, Grehn F, Lütjen-Drecoll E. Transforming growth factor β2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb development. Graefes Arch Clin Exp Ophthalmol 2001; 239:199-207. [PMID: 11405069]
36. Nguyen NX, Küchael M, Martus P, Naumann GOH. Quantification of Blood-Aqueous Barrier Breakdown after Trabeculectomy: Pseudoexfoliation versus Primary Open-Angle Glaucoma. J Glaucoma 1999; 8:18-23. [PMID: 10084270]
37. Schellings MWM, Vanhoutte D, Swinnen M, Cleutjens JP, Debets J, van Leeuwen REW, d'Hooge J, Van de Werf F, Carmeliet P, Pinto YM, Sage EH, Heymans S. Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction. J Exp Med 2009; 206:113-23. [PMID: 19103879]
38. Bradshaw AD, Sage EH. SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury. J Clin Invest 2001; 107:1049-54. [PMID: 11342565]
39. Frizell E, Liu SL, Abraham A, Ozaki I, Eghbali M, Sage EH, Zern MA. Expression of SPARC in normal and fibrotic livers. Hepatology 1995; 21:847-54. [PMID: 7875683]
40. Kanauchi M, Nishioka M, Dohi K. Secreted protein acidic and rich in cysteine (SPARC) in patients with diabetic nephropathy and tubulointerstitial injury. Diabetologia 2000; 43:1076-7. [PMID: 10990088]
41. Kuhn C, Mason R. Immunolocalization of SPARC, tenascin, and thrombospondin in pulmonary fibrosis. Am J Pathol 1995; 147:1759-69. [PMID: 7495300]
42. Pichler RH, Bassuk JA, Hugo C, Reed MJ, Eng E, Gordon KL, Pippin J, Alpers CE, Couser WG, Sage EH, Johnson RJ. SPARC is expressed by mesangial cells in experimental mesangial proliferative nephritis and inhibits plateletderived-growth-factor-medicated mesangial cell proliferation in vitro. Am J Pathol 1996; 148:1153-67. [PMID: 8644857]
43. Zhou X, Tan F, Guo X, Arnett F. Attenuation of collagen synthesis with small interfering RNA of SPARC in cultured fibroblasts from the skin of patients with scleroderma. Arthritis Rheum 2006; 54:2626-31. [PMID: 16871529]
44. Hohenester E, Maurer P, Timpl R. Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40. EMBO J 1997; 16:3778-86. [PMID: 9233787]
45. Bradshaw AD, Puolakkainen P, Dasgupta J, Davidson JM, Wight TN, Sage EH. SPARC-Null Mice Display Abnormalities in the Dermis Characterized by Decreased Collagen Fibril Diameter and Reduced Tensile Strength. J Invest Dermatol 2003; 120:949-55. [PMID: 12787119]
46. Bradshaw AD, Graves DC, Motamed K, Sage EH. SPARC-null mice exhibit increased adiposity without significant differences in overall body weight. Proc Natl Acad Sci USA 2003; 100:6045-50. [PMID: 12721366]
47. Bradshaw AD, Baicu CF, Rentz TJ, Van Laer AO, Boggs J, Lacy JM, Zile MR. Pressure Overload-Induced Alterations in Fibrillar Collagen Content and Myocardial Diastolic Function: Role of Secreted Protein Acidic and Rich in Cysteine (SPARC) in Post-Synthetic Procollagen Processing. Circulation 2009; 119:269-80. [PMID: 19118257]