Synthesis and anti-Hepatitis B virus activity of a novel class of thiazolylbenzimidazole derivatives

Archiv der Pharmazie

Volumn 344, Issue 2, 2011, Pages 78-83

  Luo, Yu ^a   Yao, Jia Ping ^a   Yang, Li ^b   Feng, Chun Lan ^b   Tang, Wei ^b   Wang, Gui Feng ^b   Zuo, Jian Pin ^b   Lu, Wei ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Anti HBV; Synthesis; Thiazolylbenzimidazole

Indexed keywords

1 BENZYL 2 (THIAZOL 4 YL) 1H BENZOIMIDAZOLE 5 CARBOXYLIC ACID; 1 BENZYL N METHYL 2 (THIAZOL 4 YL) 1H BENZOIMIDAZOLE 5 CARBOXAMIDE; 1 BENZYL N,N DIMETHYL 2 (THIAZOL 4 YL) 1H BENZOIMIDAZOLE 5 CARBOXAMIDE; 1 METHYL 2 (THIAZOL 4 YL) 1H BENZOIMIDAZOLE 5 CARBOXYLIC ACID; 1 METHYL 2 [(2 METHYLTHIAZOL 4 YL)METHYL] 1H BENZOIMIDAZOLE 5 CARBOXYLIC ACID; ANTIVIRUS AGENT; BENZIMIDAZOLE DERIVATIVE; BENZYL 2 [(2 METHYLTHIAZOL 4 YL)METHYL] 1H BENZOIMIDAZOLE 5 CARBOXYLIC ACID; LAMIVUDINE; METHYL 1 BENZYL 2 (THIAZOL 4 YL) 1H BENZOIMIDAZOLE 5 CARBOXYLATE; METHYL 1 BENZYL 2 [(2 METHYLTHIAZOL 4 YL)METHYL] 1H BENZOIMIDAZOLE 5 CARBOXYLATE; METHYL 1 METHYL 2 (THIAZOL 4 YL) 1H BENZOIMIDAZOLE 5 CARBOXYLATE; METHYL 1 METHYL 2 [(2 METHYLTHIAZOL 4 YL)METHYL] 1H BENZOIMIDAZOLE 5 CARBOXYLATE; N,1 DIMETHYL 2 (THIAZOL 4 YL) 1H BENZOIMIDAZOLE 5 CARBOXAMIDE; N,N,1 TRIMETHYL 2 (THIAZOL 4 YL) 1H BENZOIMIDAZOLE 5 CARBOXAMIDE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HEPATITIS B VIRUS; IC 50; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTIVIRAL AGENTS; BENZIMIDAZOLES; CELL DEATH; DRUG SCREENING ASSAYS, ANTITUMOR; HEP G2 CELLS; HEPATITIS B VIRUS; HUMANS; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79551694654     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201000167     Document Type: Article

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