Rational design and synthesis of 2,2-bisheterocycle tandem derivatives as non-nucleoside hepatitis BV irus inhibitors

ChemMedChem

Volumn 3, Issue 9, 2008, Pages 1316-1321

  Chen, Hai Jun ^a   Wang, Wen Long ^a   Wang, Gui Feng ^a   Shi, Li Ping ^a   Gu, Min ^a   Ren, Yu Dan ^a   Hou, Li Fei ^a   He, Pei Lan ^a   Zhu, Feng Hua ^a   Zhong, Xian Gen ^a   Tang, Wei ^a   Zuo, Jian Ping ^a   Nan, Fa Jun ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

2,2 bisheterocycle tandem; Antiviral agents; Hepatitis B virus; Leucamide A; Non nucleoside inhibitors

Indexed keywords

ANTIVIRUS AGENT; FUSED HETEROCYCLIC RINGS; THIAZOLE DERIVATIVE; VIRUS PROTEIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; HEPATITIS B VIRUS; MICROBIOLOGICAL EXAMINATION; MOLECULAR LIBRARY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; VIRUS REPLICATION;

ANTIVIRAL AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; DRUG DESIGN; HEPATITIS B VIRUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; SMALL MOLECULE LIBRARIES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 54849421759     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200800136     Document Type: Article

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