Trichostatin A inhibits TGF-Β1 induced in vitro chondrogenesis of hMSCs through Sp1 suppression

Differentiation

Volumn 81, Issue 2, 2011, Pages 119-126

  Wang, Jung Pan ^a,b   Wen, Ming Hsuan ^b   Chen, Yi Te ^a   Lee, Hsieh Hsing ^b   Chiang, En Rung ^a,b   Lee, Yi Ting ^a,b   Liu, Chien Lin ^a,b   Chen, Tain Hsiung ^a,b   Hung, Shih Chieh ^a,b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Chondrogenesis; Human mesenchymal stem cells; Transforming growth factor 1; Trichostatin A

Indexed keywords

AGGRECAN; COLLAGEN TYPE 2; MESSENGER RNA; PROTEIN COL2A1; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SOX9; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA1; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHONDROGENESIS; CONTROLLED STUDY; CULTURE MEDIUM; DRUG MECHANISM; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AGGRECANS; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROGENESIS; COLLAGEN TYPE II; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; IMMUNOGLOBULINS; MESENCHYMAL STEM CELLS; PLICAMYCIN; SMAD PROTEINS; SOX9 TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

EID: 79551682830     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2010.10.003     Document Type: Article

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