Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells

European Journal of Pharmacology

Volumn 591, Issue 1-3, 2008, Pages 36-42

  Chen, Ching Jiunn ^a   Chang, Wen Chang ^b   Chen, Ben Kuen ^b  

^a CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

12(S) lipoxygenase; c Jun; Epidermal growth factor; p300; Sp1; Trichostatin A

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; EPIDERMAL GROWTH FACTOR; MESSENGER RNA; PROTEIN P300; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR SP1; TRICHOSTATIN A;

ACETYLATION; ARTICLE; CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMAGE ANALYSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

ARACHIDONATE 12-LIPOXYGENASE; BLOTTING, WESTERN; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DOSE-RESPONSE RELATIONSHIP, DRUG; E1A-ASSOCIATED P300 PROTEIN; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION; HUMANS; HYDROXAMIC ACIDS; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-JUN; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR;

EID: 48849111142     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.06.041     Document Type: Article

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