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Volumn 6, Issue 1, 2011, Pages 44-49

Transplantation of genetically modified haematopoietic stem cells to induce antigen-specific tolerance as a cure for autoimmune diseases

Author keywords

Autoimmune diseases; Dendritic cells; Haematopoietic stem cells; Immune tolerance; Tissue repair; Transplantation

Indexed keywords

ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSCRIPTION FACTOR FOXP3;

EID: 79551655118     PISSN: 1574888X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488811794480672     Document Type: Article
Times cited : (3)

References (64)
  • 2
    • 0016153945 scopus 로고
    • Transplantation of autoimmune potential. I. Development of antinuclear antibodies in H-2 histocompatible recipients of bone marrow from New Zealand Black mice
    • Morton JI, Siegel BV. Transplantation of autoimmune potential. I. Development of antinuclear antibodies in H-2 histocompatible recipients of bone marrow from New Zealand Black mice. Proc Natl Acad Sci USA 1974; 71: 2162-5.
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 2162-2165
    • Morton, J.I.1    Siegel, B.V.2
  • 3
    • 0028118606 scopus 로고
    • Immune ablation followed by allogeneic or autologous bone marrow transplantation: A new treatment for severe autoimmune diseases?
    • Marmont AM. Immune ablation followed by allogeneic or autologous bone marrow transplantation: a new treatment for severe autoimmune diseases? Stem Cells 1994; 12: 125-35.
    • (1994) Stem Cells , vol.12 , pp. 125-135
    • Marmont, A.M.1
  • 4
    • 58149302512 scopus 로고    scopus 로고
    • Transmission of type 1 diabetes by bone marrow transplantation: A case report
    • Mellouli F, Ksouri H, Torjmen L, et al. Transmission of type 1 diabetes by bone marrow transplantation: a case report. Pediatr Transplant 2009; 13: 119-22
    • (2009) Pediatr Transplant , vol.13 , pp. 119-122
    • Mellouli, F.1    Ksouri, H.2    Torjmen, L.3
  • 5
    • 0036826849 scopus 로고    scopus 로고
    • Experimental basis of hematopoietic stem cell transplantation for treatment of autoimmune diseases
    • van Bekkum DW. Experimental basis of hematopoietic stem cell transplantation for treatment of autoimmune diseases. J Leukoc Biol 2002; 72: 609-20
    • (2002) J Leukoc Biol , vol.72 , pp. 609-620
    • van Bekkum, D.W.1
  • 6
    • 39149112225 scopus 로고    scopus 로고
    • Will hematopoietic stem cell transplantation cure human autoimmune diseases?
    • Marmont AM. Will hematopoietic stem cell transplantation cure human autoimmune diseases? J Autoimmun 2008; 30: 145-50
    • (2008) J Autoimmun , vol.30 , pp. 145-150
    • Marmont, A.M.1
  • 7
    • 20444485767 scopus 로고    scopus 로고
    • Cellular and genetic mechanisms of self tolerance and autoimmunity
    • Goodnow CC, Sprent J, de St Groth BF, Vinuesa CG. Cellular and genetic mechanisms of self tolerance and autoimmunity. Nature 2005; 435: 590-7
    • (2005) Nature , vol.435 , pp. 590-597
    • Goodnow, C.C.1    Sprent, J.2    de St Groth, B.F.3    Vinuesa, C.G.4
  • 8
    • 4544258485 scopus 로고    scopus 로고
    • Self-representation in the thymus: An extended view
    • Kyewski B, Derbinski J. Self-representation in the thymus: an extended view. Nat Rev Immunol 2004; 4: 688-98
    • (2004) Nat Rev Immunol , vol.4 , pp. 688-698
    • Kyewski, B.1    Derbinski, J.2
  • 9
    • 20344406479 scopus 로고    scopus 로고
    • Dendritic cells: Sentinels of immunity and tolerance
    • Kubach J, Becker C, Schmitt E, et al. Dendritic cells: sentinels of immunity and tolerance. Int J Hematol 2005; 81: 197-203
    • (2005) Int J Hematol , vol.81 , pp. 197-203
    • Kubach, J.1    Becker, C.2    Schmitt, E.3
  • 10
    • 7044220808 scopus 로고    scopus 로고
    • Regulating self-tolerance by deregulating gene expression
    • Gotter J, Kyewski B. Regulating self-tolerance by deregulating gene expression. Curr Opin Immunol 2004; 16: 741-5
    • (2004) Curr Opin Immunol , vol.16 , pp. 741-745
    • Gotter, J.1    Kyewski, B.2
  • 11
    • 7244227646 scopus 로고    scopus 로고
    • Gene dosage--limiting role of aire in thymic expression, clonal deletion, and organ-specific auto- immunity
    • Liston A, Gray DH, Lesage S, et al. Gene dosage--limiting role of aire in thymic expression, clonal deletion, and organ-specific auto- immunity. J Exp Med 2004; 200: 1015-26
    • (2004) J Exp Med , vol.200 , pp. 1015-1026
    • Liston, A.1    Gray, D.H.2    Lesage, S.3
  • 12
    • 0035011574 scopus 로고    scopus 로고
    • Immunoablation followed or not by hematopoietic stem cells as an intense therapy for severe autoimmune diseases. New perspectives, new problems
    • Marmont AM. Immunoablation followed or not by hematopoietic stem cells as an intense therapy for severe autoimmune diseases. New perspectives, new problems. Haematologica 2001; 86: 337-45
    • (2001) Haematologica , vol.86 , pp. 337-345
    • Marmont, A.M.1
  • 13
    • 0030982123 scopus 로고    scopus 로고
    • Pre-existing autoimmune disease in patients with long-term survival after allogeneic bone marrow transplantation
    • Nelson JL, Torrez R, Louie FM, Choe OS, Storb R, Sullivan KM. Pre-existing autoimmune disease in patients with long-term survival after allogeneic bone marrow transplantation. J Rheumatol (Suppl) 1997; 48: 23-9
    • (1997) J Rheumatol (Suppl) , vol.48 , pp. 23-29
    • Nelson, J.L.1    Torrez, R.2    Louie, F.M.3    Choe, O.S.4    Storb, R.5    Sullivan, K.M.6
  • 14
    • 33646948505 scopus 로고    scopus 로고
    • Non-myeloablative allogeneic stem cell transplant in a patient with refractory systemic lupus erythematosus
    • Lu Q, Lu L, Niu X, Guo Y, Parino GR, Liu D. Non-myeloablative allogeneic stem cell transplant in a patient with refractory systemic lupus erythematosus. Bone Marrow Transplant 2006; 37: 979-81
    • (2006) Bone Marrow Transplant , vol.37 , pp. 979-981
    • Lu, Q.1    Lu, L.2    Niu, X.3    Guo, Y.4    Parino, G.R.5    Liu, D.6
  • 15
    • 4043099123 scopus 로고    scopus 로고
    • Induction of remission of severe and refractory rheumatoid arthritis by allogeneic mixed chi-merism
    • Burt RK, Oyama Y, Verda L, et al. Induction of remission of severe and refractory rheumatoid arthritis by allogeneic mixed chi-merism. Arthritis Rheum 2004; 50: 2466-70
    • (2004) Arthritis Rheum , vol.50 , pp. 2466-2470
    • Burt, R.K.1    Oyama, Y.2    Verda, L.3
  • 16
    • 10044287310 scopus 로고    scopus 로고
    • Nonmyeloablative stem cell transplant in a patient with advanced systemic sclerosis and systemic lupus erythematosus
    • Khorshid O, Hosing C, Bibawi S, et al. Nonmyeloablative stem cell transplant in a patient with advanced systemic sclerosis and systemic lupus erythematosus. J Rheumatol 2004; 31: 2513-6
    • (2004) J Rheumatol , vol.31 , pp. 2513-2516
    • Khorshid, O.1    Hosing, C.2    Bibawi, S.3
  • 17
    • 0031053084 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplant for chronic myelogenous leukemia in a patient with multiple sclerosis
    • McAllister LD, Beatty PG, Rose J. Allogeneic bone marrow transplant for chronic myelogenous leukemia in a patient with multiple sclerosis. Bone Marrow Transplant 1997; 19: 395-7
    • (1997) Bone Marrow Transplant , vol.19 , pp. 395-397
    • McAllister, L.D.1    Beatty, P.G.2    Rose, J.3
  • 19
    • 38449091801 scopus 로고    scopus 로고
    • Failure of allogeneic bone marrow transplantation to arrest disease activity in multiple sclerosis
    • Jeffery DR. Failure of allogeneic bone marrow transplantation to arrest disease activity in multiple sclerosis. Mult Scler 2007; 13: 1071-5
    • (2007) Mult Scler , vol.13 , pp. 1071-1075
    • Jeffery, D.R.1
  • 20
    • 0024791136 scopus 로고
    • Regression of adjuvant-induced arthritis in rats following bone marrow transplantation
    • van Bekkum DW, Bohre EP, Houben PF, Knaan-Shanzer S. Regression of adjuvant-induced arthritis in rats following bone marrow transplantation. Proc Natl Acad Sci USA 1989; 86: 10090-4
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 10090-10094
    • van Bekkum, D.W.1    Bohre, E.P.2    Houben, P.F.3    Knaan-Shanzer, S.4
  • 21
    • 21344463992 scopus 로고    scopus 로고
    • Haematopoietic stem cell transplantation in the treatment of severe autoimmune disease: Results from phase I/II studies, prospective randomized trials and future directions
    • Tyndall A, Saccardi R. Haematopoietic stem cell transplantation in the treatment of severe autoimmune disease: results from phase I/II studies, prospective randomized trials and future directions. Clin Exp Immunol 2005; 141: 1-9
    • (2005) Clin Exp Immunol , vol.141 , pp. 1-9
    • Tyndall, A.1    Saccardi, R.2
  • 22
    • 14144250048 scopus 로고    scopus 로고
    • Haemopoietic stem cell transplantation in autoimmune diseases: A European perspective
    • Hough RE, Snowden JA, Wulffraat NM. Haemopoietic stem cell transplantation in autoimmune diseases: a European perspective. Br J Haematol 2005; 128: 432-59
    • (2005) Br J Haematol , vol.128 , pp. 432-459
    • Hough, R.E.1    Snowden, J.A.2    Wulffraat, N.M.3
  • 23
    • 4544350692 scopus 로고    scopus 로고
    • Haematopoietic stem cell transplantation for autoimmune disorders: The American perspective
    • Popat U, Krance R. Haematopoietic stem cell transplantation for autoimmune disorders: the American perspective. Br J Haematol 2004; 126: 637-49
    • (2004) Br J Haematol , vol.126 , pp. 637-649
    • Popat, U.1    Krance, R.2
  • 24
    • 0346236665 scopus 로고    scopus 로고
    • Autologous stem cell transplants in treatment of multiple sclerosis: Where we stand and future prospects
    • Fassas A. Autologous stem cell transplants in treatment of multiple sclerosis: where we stand and future prospects. Int J Hematol 2002; 76 (Suppl) 1: 223-225
    • (2002) Int J Hematol , vol.76 , Issue.1 , pp. 223-225
    • Fassas, A.1
  • 25
    • 0034093120 scopus 로고    scopus 로고
    • Autologous stem cell transplantation in progressive multiple sclerosis--an interim analysis of efficacy
    • Fassas A, Anagnostopoulos A, Kazis A, et al. Autologous stem cell transplantation in progressive multiple sclerosis--an interim analysis of efficacy. J Clin Immunol 2000; 20: 24-30
    • (2000) J Clin Immunol , vol.20 , pp. 24-30
    • Fassas, A.1    Anagnostopoulos, A.2    Kazis, A.3
  • 26
    • 49949108452 scopus 로고    scopus 로고
    • Clinical outcome 6 years after autologous hematopoietic stem cell transplantation in multiple sclerosis
    • Saiz A, Blanco Y, Berenguer J, et al. Clinical outcome 6 years after autologous hematopoietic stem cell transplantation in multiple sclerosis. Neurologia 2008; 405-7
    • (2008) Neurologia , pp. 405-407
    • Saiz, A.1    Blanco, Y.2    Berenguer, J.3
  • 27
    • 35349010569 scopus 로고    scopus 로고
    • Autologous stem cell transplantation in autoimmune diseases
    • Passweg J, Tyndall A. Autologous stem cell transplantation in autoimmune diseases. Semin Hematol 2007; 44: 278-85
    • (2007) Semin Hematol , vol.44 , pp. 278-285
    • Passweg, J.1    Tyndall, A.2
  • 28
    • 11144305796 scopus 로고    scopus 로고
    • Autologous haematopoietic-stem-cell transplantation for multiple sclerosis
    • Blanco Y, Saiz A, Carreras E, Graus F. Autologous haematopoietic-stem-cell transplantation for multiple sclerosis. Lancet Neurol 2005; 4: 54-63
    • (2005) Lancet Neurol , vol.4 , pp. 54-63
    • Blanco, Y.1    Saiz, A.2    Carreras, E.3    Graus, F.4
  • 29
    • 60049083956 scopus 로고    scopus 로고
    • Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: A phase I/II study
    • Burt RK, Loh Y, Cohen B, et al. Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study. Lancet Neurol 2009; 8: 244-53
    • (2009) Lancet Neurol , vol.8 , pp. 244-253
    • Burt, R.K.1    Loh, Y.2    Cohen, B.3
  • 30
    • 2942700114 scopus 로고    scopus 로고
    • Autologous stem cell transplantation for systemic lupus erythematosus
    • Jayne D, Passweg J, Marmont A, et al. Autologous stem cell transplantation for systemic lupus erythematosus. Lupus 2004; 13: 168-76
    • (2004) Lupus , vol.13 , pp. 168-176
    • Jayne, D.1    Passweg, J.2    Marmont, A.3
  • 31
    • 54149083949 scopus 로고    scopus 로고
    • Stem cell transplantation for rheumatic autoimmune diseases
    • Hugle T, van Laar JM. Stem cell transplantation for rheumatic autoimmune diseases. Arthritis Res Ther 2008; 10: 217
    • (2008) Arthritis Res Ther , vol.10 , pp. 217
    • Hugle, T.1    van Laar, J.M.2
  • 32
    • 0041331742 scopus 로고    scopus 로고
    • Modeling TCR signaling complex formation in positive selection
    • Hare KJ, Pongracz J, Jenkinson EJ, Anderson G. Modeling TCR signaling complex formation in positive selection. J Immunol 2003; 171: 2825-31
    • (2003) J Immunol , vol.171 , pp. 2825-2831
    • Hare, K.J.1    Pongracz, J.2    Jenkinson, E.J.3    Anderson, G.4
  • 33
    • 0031058466 scopus 로고    scopus 로고
    • Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo
    • Brocker T, Riedinger M, Karjalainen K. Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo. J Exp Med 1997; 185: 541-50
    • (1997) J Exp Med , vol.185 , pp. 541-550
    • Brocker, T.1    Riedinger, M.2    Karjalainen, K.3
  • 34
    • 0028362294 scopus 로고
    • Positive selection by purified MHC class II+ thymic epithelial cells in vitro: Costimulatory signals mediated by B7 are not involved
    • Jenkinson EJ, Anderson G, Moore NC, Smith CA, Owen JJ. Positive selection by purified MHC class II+ thymic epithelial cells in vitro: costimulatory signals mediated by B7 are not involved. Dev Immunol 1994; 3: 265-71
    • (1994) Dev Immunol , vol.3 , pp. 265-271
    • Jenkinson, E.J.1    Anderson, G.2    Moore, N.C.3    Smith, C.A.4    Owen, J.J.5
  • 35
    • 58149388025 scopus 로고    scopus 로고
    • The impact of circulating dendritic cells on the development and differentiation of thymo-cytes
    • Proietto AI, van Dommelen S, Wu L. The impact of circulating dendritic cells on the development and differentiation of thymo-cytes. Immunol Cell Biol 2009; 87: 39-45
    • (2009) Immunol Cell Biol , vol.87 , pp. 39-45
    • Proietto, A.I.1    van Dommelen, S.2    Wu, L.3
  • 36
    • 63449133991 scopus 로고    scopus 로고
    • Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus
    • Li J, Park J, Foss D, Goldschneider I. Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus. J Exp Med 2009; 206: 607-22
    • (2009) J Exp Med , vol.206 , pp. 607-622
    • Li, J.1    Park, J.2    Foss, D.3    Goldschneider, I.4
  • 39
    • 51349095960 scopus 로고    scopus 로고
    • Tuning microenvironments: Induction of regulatory T cells by dendritic cells
    • Belkaid Y, Oldenhove G. Tuning microenvironments: induction of regulatory T cells by dendritic cells. Immunity 2008; 29: 362-71
    • (2008) Immunity , vol.29 , pp. 362-371
    • Belkaid, Y.1    Oldenhove, G.2
  • 40
    • 63149172076 scopus 로고    scopus 로고
    • Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells
    • Yamazaki S, Steinman RM. Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells. J Dermatol Sci 2009; 54: 69-75
    • (2009) J Dermatol Sci , vol.54 , pp. 69-75
    • Yamazaki, S.1    Steinman, R.M.2
  • 41
    • 0035320679 scopus 로고    scopus 로고
    • Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
    • Jordan MS, Boesteanu A, Reed AJ, et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001; 2: 301-6
    • (2001) Nat Immunol , vol.2 , pp. 301-306
    • Jordan, M.S.1    Boesteanu, A.2    Reed, A.J.3
  • 42
    • 34248598295 scopus 로고    scopus 로고
    • Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
    • Aschenbrenner K, D'Cruz LM, Vollmann EH, et al. Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells. Nat Immunol 2007; 8: 351-8
    • (2007) Nat Immunol , vol.8 , pp. 351-358
    • Aschenbrenner, K.1    D'Cruz, L.M.2    Vollmann, E.H.3
  • 43
    • 0027220205 scopus 로고
    • An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus
    • Alderuccio F, Toh BH, Tan SS, Gleeson PA, van Driel IR. An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus. J Exp Med 1993; 178: 419-26
    • (1993) J Exp Med , vol.178 , pp. 419-426
    • Alderuccio, F.1    Toh, B.H.2    Tan, S.S.3    Gleeson, P.A.4    van Driel, I.R.5
  • 44
    • 0031025574 scopus 로고    scopus 로고
    • Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice
    • French MB, Allison J, Cram DS, et al. Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice. Diabetes 1997; 46: 34-9
    • (1997) Diabetes , vol.46 , pp. 34-39
    • French, M.B.1    Allison, J.2    Cram, D.S.3
  • 45
    • 0033987174 scopus 로고    scopus 로고
    • Transgenic expression of an immunologically privileged retinal antigen extraocularly enhances self tolerance and abrogates susceptibility to autoimmune uveitis
    • Xu H, Wawrousek EF, Redmond TM, et al. Transgenic expression of an immunologically privileged retinal antigen extraocularly enhances self tolerance and abrogates susceptibility to autoimmune uveitis. Eur J Immunol 2000; 30: 272-8
    • (2000) Eur J Immunol , vol.30 , pp. 272-278
    • Xu, H.1    Wawrousek, E.F.2    Redmond, T.M.3
  • 46
    • 0037325918 scopus 로고    scopus 로고
    • Tolerance established in autoimmune disease by mating or bone marrow transplantation that target autoantigen to thymus
    • Murphy K, Biondo M, Toh BH, Alderuccio F. Tolerance established in autoimmune disease by mating or bone marrow transplantation that target autoantigen to thymus. Int Immunol 2003; 15: 269-77
    • (2003) Int Immunol , vol.15 , pp. 269-277
    • Murphy, K.1    Biondo, M.2    Toh, B.H.3    Alderuccio, F.4
  • 47
    • 0038326717 scopus 로고    scopus 로고
    • Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes
    • Steptoe RJ, Ritchie JM, Harrison LC. Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes. J Clin Invest 2003; 111: 1357-63
    • (2003) J Clin Invest , vol.111 , pp. 1357-1363
    • Steptoe, R.J.1    Ritchie, J.M.2    Harrison, L.C.3
  • 48
    • 71849087808 scopus 로고    scopus 로고
    • Transplantation of bone marrow transduced to express self-antigen establishes deletional tolerance and permanently remits autoimmune disease
    • Chan J, Ban EJ, Chun KH, et al. Transplantation of bone marrow transduced to express self-antigen establishes deletional tolerance and permanently remits autoimmune disease. J Immunol 2008; 181: 7571-80
    • (2008) J Immunol , vol.181 , pp. 7571-7580
    • Chan, J.1    Ban, E.J.2    Chun, K.H.3
  • 49
    • 33751247344 scopus 로고    scopus 로고
    • Transplantation of bone marrow genetically engineered to express proinsulin II protects against autoimmune insulitis in NOD mice
    • Chan J, Clements W, Field J, et al. Transplantation of bone marrow genetically engineered to express proinsulin II protects against autoimmune insulitis in NOD mice. J Gene Med 2006; 8: 1281-90
    • (2006) J Gene Med , vol.8 , pp. 1281-1290
    • Chan, J.1    Clements, W.2    Field, J.3
  • 50
    • 28844477590 scopus 로고    scopus 로고
    • Bone marrow transplantation combined with gene therapy to induce antigen-specific tolerance and ameliorate EAE
    • Xu B, Haviernik P, Wolfraim LA, Bunting KD, Scott DW. Bone marrow transplantation combined with gene therapy to induce antigen-specific tolerance and ameliorate EAE. Mol Ther 2006; 13: 42-48
    • (2006) Mol Ther , vol.13 , pp. 42-48
    • Xu, B.1    Haviernik, P.2    Wolfraim, L.A.3    Bunting, K.D.4    Scott, D.W.5
  • 52
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish CL, Chen Y, Blumenschein WM, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005; 201: 233-40
    • (2005) J Exp Med , vol.201 , pp. 233-240
    • Langrish, C.L.1    Chen, Y.2    Blumenschein, W.M.3
  • 53
    • 40449089827 scopus 로고    scopus 로고
    • Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells
    • Stromnes IM, Cerretti LM, Liggitt D, Harris RA, Goverman JM. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat Med 2008; 14: 337-42
    • (2008) Nat Med , vol.14 , pp. 337-342
    • Stromnes, I.M.1    Cerretti, L.M.2    Liggitt, D.3    Harris, R.A.4    Goverman, J.M.5
  • 54
    • 33746932112 scopus 로고    scopus 로고
    • Persistence of antigen is required to maintain transplantation tolerance induced by genetic modification of bone marrow stem cells
    • Tian C, Bagley J, Iacomini J. Persistence of antigen is required to maintain transplantation tolerance induced by genetic modification of bone marrow stem cells. Am J Transplant 2006; 6: 2202-7
    • (2006) Am J Transplant , vol.6 , pp. 2202-2207
    • Tian, C.1    Bagley, J.2    Iacomini, J.3
  • 55
    • 0013913054 scopus 로고
    • The effect of prednisolone on gastric mucosal histology, gastric secretion, and vitamin B 12 absorption in patients with pernicious anemia
    • Jeffries GH, Todd JE, Sleisenger MH. The effect of prednisolone on gastric mucosal histology, gastric secretion, and vitamin B 12 absorption in patients with pernicious anemia. J Clin Invest 1966; 45: 803-12
    • (1966) J Clin Invest , vol.45 , pp. 803-812
    • Jeffries, G.H.1    Todd, J.E.2    Sleisenger, M.H.3
  • 57
    • 0038110577 scopus 로고    scopus 로고
    • Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes
    • Zorina TD, Subbotin VM, Bertera S, et al. Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes. Stem Cells 2003; 21: 377-88
    • (2003) Stem Cells , vol.21 , pp. 377-388
    • Zorina, T.D.1    Subbotin, V.M.2    Bertera, S.3
  • 58
    • 33845294412 scopus 로고    scopus 로고
    • Remyelination is extensive in a subset of multiple sclerosis patients
    • Patrikios P, Stadelmann C, Kutzelnigg A, et al. Remyelination is extensive in a subset of multiple sclerosis patients. Brain 2006; 129: 3165-72
    • (2006) Brain , vol.129 , pp. 3165-3172
    • Patrikios, P.1    Stadelmann, C.2    Kutzelnigg, A.3
  • 59
    • 0013828898 scopus 로고
    • Electron microscopic features of multiple sclerosis lesions
    • Perier O, Gregoire A. Electron microscopic features of multiple sclerosis lesions. Brain 1965; 88: 937-52
    • (1965) Brain , vol.88 , pp. 937-952
    • Perier, O.1    Gregoire, A.2
  • 60
    • 25644434410 scopus 로고    scopus 로고
    • Enhancing central nervous system remyelination in multiple sclerosis
    • Dubois-Dalcq M, Ffrench-Constant C, Franklin RJ. Enhancing central nervous system remyelination in multiple sclerosis. Neuron 2005; 48: 9-12
    • (2005) Neuron , vol.48 , pp. 9-12
    • Dubois-Dalcq, M.1    Ffrench-Constant, C.2    Franklin, R.J.3
  • 61
    • 0034748027 scopus 로고    scopus 로고
    • Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes
    • Guz Y, Nasir I, Teitelman G. Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes. Endocrinology 2001; 142: 4956-68
    • (2001) Endocrinology , vol.142 , pp. 4956-4968
    • Guz, Y.1    Nasir, I.2    Teitelman, G.3
  • 62
    • 33745684461 scopus 로고    scopus 로고
    • Prednisolone promotes remission and gastric mucosal regeneration in experimental autoimmune gastritis
    • Biondo M, Field J, Toh BH, Alderuccio F. Prednisolone promotes remission and gastric mucosal regeneration in experimental autoimmune gastritis. J Pathol 2006; 209: 384-91
    • (2006) J Pathol , vol.209 , pp. 384-391
    • Biondo, M.1    Field, J.2    Toh, B.H.3    Alderuccio, F.4
  • 63
    • 45949104791 scopus 로고    scopus 로고
    • Methylprednisolone induces reversible clinical and pathological remission and loss of lymphocyte reactivity to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis
    • Chan J, Ban EJ, Chun KH, et al. Methylprednisolone induces reversible clinical and pathological remission and loss of lymphocyte reactivity to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis. Autoimmunity 2008; 41: 405-13
    • (2008) Autoimmunity , vol.41 , pp. 405-413
    • Chan, J.1    Ban, E.J.2    Chun, K.H.3
  • 64
    • 38149031549 scopus 로고    scopus 로고
    • Sequential myelin protein expression during remyelination reveals fast and efficient repair after central nervous system demyelination
    • Lindner M, Heine S, Haastert K, et al. Sequential myelin protein expression during remyelination reveals fast and efficient repair after central nervous system demyelination. Neuropathol Appl Neu-robiol 2008; 34: 105-14
    • (2008) Neuropathol Appl Neu-robiol , vol.34 , pp. 105-114
    • Lindner, M.1    Heine, S.2    Haastert, K.3


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