Hepatic glycogen supercompensation activates AMP-activated protein kinase, impairs insulin signaling, and reduces glycogen deposition in the liver

Diabetes

Volumn 60, Issue 2, 2011, Pages 398-407

  Winnick, Jason J ^a   An, Zhibo ^a   Ramnanan, Christopher J ^a   Smith, Marta ^a   Irimia, Jose M ^b   Neal, Doss W ^a   Moore, Mary Courtney ^a   Roach, Peter J ^b   Cherrington, Alan D ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; FRUCTOSE; GLUCOSE; GLYCOGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LACTIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; GLUCOSE INFUSION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCEMIC CONTROL; GLYCOGEN LIVER LEVEL; GLYCOGEN SYNTHESIS; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; MOUSE; NONHUMAN; OXIDATION; PORTAL VEIN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANALYSIS OF VARIANCE; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; DOGS; FATTY ACIDS, NONESTERIFIED; FEMALE; FRUCTOSE; GLUCAGON; INSULIN; LIVER; LIVER GLYCOGEN; MALE; PORTAL VEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 79551608085     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-0592     Document Type: Article

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