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Volumn 49, Issue 2, 2000, Pages 272-283

Effects of type 2 diabetes on the ability of insulin and glucose to regulate splanchnic and muscle glucose metabolism: Evidence for a defect in hepatic glucokinase activity

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOKINASE; GLUCOSE; INSULIN; SOMATOSTATIN;

EID: 0033985724     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.49.2.272     Document Type: Article
Times cited : (170)

References (88)
  • 1
  • 2
    • 0021994683 scopus 로고
    • Effects of insulin on peripheral and splanchnic glucose metabolism in non-insulin-dependent (type II) diabetes mellitus
    • DeFronzo RA, Gunnarsson R, Björkman O, Olsson M, Wahren J: Effects of insulin on peripheral and splanchnic glucose metabolism in non-insulin-dependent (type II) diabetes mellitus. J Clin Invest 76:149-155, 1985
    • (1985) J Clin Invest , vol.76 , pp. 149-155
    • DeFronzo, R.A.1    Gunnarsson, R.2    Björkman, O.3    Olsson, M.4    Wahren, J.5
  • 4
    • 0025175753 scopus 로고
    • Effect of insulin on oxidation of intracellularly and extracellularly derived glucose in patients with NTDDM
    • Butler PC, Kryshak EJ, Marsh M, Rizza RA: Effect of insulin on oxidation of intracellularly and extracellularly derived glucose in patients with NTDDM. Diabetes 39:1373-1380, 1990
    • (1990) Diabetes , vol.39 , pp. 1373-1380
    • Butler, P.C.1    Kryshak, E.J.2    Marsh, M.3    Rizza, R.A.4
  • 5
    • 0026654879 scopus 로고
    • Intracellular defects in glucose metabolism in obese patients with NIDDM
    • Kelley DE, Mokan M, Mandarino LJ: Intracellular defects in glucose metabolism in obese patients with NIDDM. Diabetes 41:698-706, 1992
    • (1992) Diabetes , vol.41 , pp. 698-706
    • Kelley, D.E.1    Mokan, M.2    Mandarino, L.J.3
  • 7
    • 0028847791 scopus 로고
    • The effects of non-insulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues
    • Turk D, Alzaid A, Dinneen S, Nair KS, Rizza R: The effects of non-insulin-dependent diabetes mellitus on the kinetics of onset of insulin action in hepatic and extrahepatic tissues. J Clin Invest 95:755-762, 1995
    • (1995) J Clin Invest , vol.95 , pp. 755-762
    • Turk, D.1    Alzaid, A.2    Dinneen, S.3    Nair, K.S.4    Rizza, R.5
  • 8
    • 0020679381 scopus 로고
    • Evidence for restoration of hepatic glucose processing in type I diabetes mellitus
    • Aoki TT, Vlachokosta FV, Foss MC, Meistas MT: Evidence for restoration of hepatic glucose processing in type I diabetes mellitus. J Clin Invest 71:937-939, 1983
    • (1983) J Clin Invest , vol.71 , pp. 937-939
    • Aoki, T.T.1    Vlachokosta, F.V.2    Foss, M.C.3    Meistas, M.T.4
  • 9
    • 0019761497 scopus 로고
    • Mechanism and significance of insulin resistance in non-insulin-dependent diabetes mellitus
    • Rizza RA, Mandarino LJ, Gerich JE: Mechanism and significance of insulin resistance in non-insulin-dependent diabetes mellitus. Diabetes 30:990-995, 1981
    • (1981) Diabetes , vol.30 , pp. 990-995
    • Rizza, R.A.1    Mandarino, L.J.2    Gerich, J.E.3
  • 10
    • 0031054198 scopus 로고    scopus 로고
    • Impaired basal glucose effectiveness in NTDDM: Contribution of defects in glucose disappearance and production, measured using an optimized minimal model independent protocol
    • Basu A, Caumo A, Bettini F, Gelisio A, Alzaid A, Cobelli C: Impaired basal glucose effectiveness in NTDDM: contribution of defects in glucose disappearance and production, measured using an optimized minimal model independent protocol. Diabetes 46:421-432, 1997
    • (1997) Diabetes , vol.46 , pp. 421-432
    • Basu, A.1    Caumo, A.2    Bettini, F.3    Gelisio, A.4    Alzaid, A.5    Cobelli, C.6
  • 12
    • 0027234332 scopus 로고
    • Effect of a sulfonylurea (gliclazide) treatment on insulin sensitivity and glucose-mediated glucose disposal in patients with non-insulin-dependent diabetes mellitus (NIDDM)
    • Wajchenberg BL, Santomauro ATMG, Porrelli RN: Effect of a sulfonylurea (gliclazide) treatment on insulin sensitivity and glucose-mediated glucose disposal in patients with non-insulin-dependent diabetes mellitus (NIDDM). Diabetes Res Clin Pract 20:147-154, 1993
    • (1993) Diabetes Res Clin Pract , vol.20 , pp. 147-154
    • Wajchenberg, B.L.1    Santomauro, A.T.M.G.2    Porrelli, R.N.3
  • 14
    • 0031719659 scopus 로고    scopus 로고
    • Normal glucose-induced suppression of glucose production but impaired stimulation of glucose disposal in type 2 diabetes: Evidence for a concentration-dependent defect in uptake
    • Nielsen MF, Basu R, Wise S, Caumo A, Cobelli C, Rizza RA: Normal glucose-induced suppression of glucose production but impaired stimulation of glucose disposal in type 2 diabetes: evidence for a concentration-dependent defect in uptake. Diabetes 47:1735-1747, 1998
    • (1998) Diabetes , vol.47 , pp. 1735-1747
    • Nielsen, M.F.1    Basu, R.2    Wise, S.3    Caumo, A.4    Cobelli, C.5    Rizza, R.A.6
  • 15
    • 0030671249 scopus 로고    scopus 로고
    • Evidence for decreased splanchnic glucose uptake after oral glucose administration in non-insulin-dependent diabetes mellitus
    • Ludvik B, Nolan JJ, Roberts A, Baloga J, Joyce M, Bell JM, Olefsky JM: Evidence for decreased splanchnic glucose uptake after oral glucose administration in non-insulin-dependent diabetes mellitus. J Clin Invest 100:2354-2361, 1997
    • (1997) J Clin Invest , vol.100 , pp. 2354-2361
    • Ludvik, B.1    Nolan, J.J.2    Roberts, A.3    Baloga, J.4    Joyce, M.5    Bell, J.M.6    Olefsky, J.M.7
  • 16
    • 0017851158 scopus 로고
    • Influence of maturity-onset diabetes on splanchnic glucose balance after oral glucose ingestion
    • Felig P, Wahren J, Hendler R: Influence of maturity-onset diabetes on splanchnic glucose balance after oral glucose ingestion. Diabetes 27:121-126, 1978
    • (1978) Diabetes , vol.27 , pp. 121-126
    • Felig, P.1    Wahren, J.2    Hendler, R.3
  • 19
    • 0030025032 scopus 로고    scopus 로고
    • A model to measure insulin effects on glucose transport and phosphorylation in musde: A three-tracer study
    • Saccomani MP, Bonadonna RC, Bier DM, DeFronzo RA, Cobelli C: A model to measure insulin effects on glucose transport and phosphorylation in musde: a three-tracer study. Am J Physiol 270:E170-E185, 1996
    • (1996) Am J Physiol , vol.270
    • Saccomani, M.P.1    Bonadonna, R.C.2    Bier, D.M.3    DeFronzo, R.A.4    Cobelli, C.5
  • 20
    • 0025193356 scopus 로고
    • m, glucose transporter of islets of Langerhans is functionally similar to the low-affinity transporter of liver and has an identical primary sequence
    • m, glucose transporter of islets of Langerhans is functionally similar to the low-affinity transporter of liver and has an identical primary sequence. J Biol Chem 265:6548-6551, 1990
    • (1990) J Biol Chem , vol.265 , pp. 6548-6551
    • Johnson, J.H.1    Newgard, C.B.2    Milburn, J.L.3    Lodish, H.F.4    Thorens, B.5
  • 21
    • 0027420730 scopus 로고
    • The glucose transporter family: Structure, function, and tissue-specific expression
    • Gould GW, Holman GD: The glucose transporter family: structure, function, and tissue-specific expression. Biochem J 295:329-341, 1993
    • (1993) Biochem J , vol.295 , pp. 329-341
    • Gould, G.W.1    Holman, G.D.2
  • 22
    • 0023251849 scopus 로고
    • Regulation of glycogen synthase and phosphorylase activities by glucose and insulin in human skeletal muscle
    • Yki-Jarvinen H, Mott D, Young AA, Stone K, Bogardus C: Regulation of glycogen synthase and phosphorylase activities by glucose and insulin in human skeletal muscle. J Clin Inivest 80:95-100, 1987
    • (1987) J Clin Inivest , vol.80 , pp. 95-100
    • Yki-Jarvinen, H.1    Mott, D.2    Young, A.A.3    Stone, K.4    Bogardus, C.5
  • 23
    • 0020858813 scopus 로고
    • Response of liver glycogen synthase and phosphorylase to in vivo glucose and glucose analogues
    • Nuttall FQ, Theen JW, Niewoehner C, Gilboe DP: Response of liver glycogen synthase and phosphorylase to in vivo glucose and glucose analogues. Am J Physiol 245:E521-E527, 1983
    • (1983) Am J Physiol , vol.245
    • Nuttall, F.Q.1    Theen, J.W.2    Niewoehner, C.3    Gilboe, D.P.4
  • 24
    • 0017817456 scopus 로고
    • Insulin regulation of hepatic glycogen synthase and phosphorylase
    • Witters LA, Avruch J: Insulin regulation of hepatic glycogen synthase and phosphorylase. Biochemistry 17:406-410, 1978
    • (1978) Biochemistry , vol.17 , pp. 406-410
    • Witters, L.A.1    Avruch, J.2
  • 25
    • 0025860114 scopus 로고
    • Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus
    • Damsbo P, Vaag A, Hother-Nielsen O, Beck-Nielsen H: Reduced glycogen synthase activity in skeletal muscle from obese patients with and without type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 34:239-245, 1991
    • (1991) Diabetologia , vol.34 , pp. 239-245
    • Damsbo, P.1    Vaag, A.2    Hother-Nielsen, O.3    Beck-Nielsen, H.4
  • 26
    • 0018381090 scopus 로고
    • The inactivation of glycogen phosphorylase is not a prerequisite for the activation of liver glycogen synthase
    • Ciudad CJ, Massague J, Guinovart JJ: The inactivation of glycogen phosphorylase is not a prerequisite for the activation of liver glycogen synthase. FEBS Lett 99:321-324, 1979
    • (1979) FEBS Lett , vol.99 , pp. 321-324
    • Ciudad, C.J.1    Massague, J.2    Guinovart, J.J.3
  • 27
    • 0032520870 scopus 로고    scopus 로고
    • Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans
    • Petersen KF, Laurent D, Rothman DL, Cline GW, Shulman GL Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans. J Clin Invest 101:1203-1209, 1998
    • (1998) J Clin Invest , vol.101 , pp. 1203-1209
    • Petersen, K.F.1    Laurent, D.2    Rothman, D.L.3    Cline, G.W.4    Shulman, G.L.5
  • 28
    • 0020684724 scopus 로고
    • Regulation of splanchnic and peripheral glucose uptake by insulin and hyperglycemia in man
    • DeFronzo RA, Ferrannini E, Hendler R, Felig P, Wahren J: Regulation of splanchnic and peripheral glucose uptake by insulin and hyperglycemia in man. Diabetes 32:35-45, 1983
    • (1983) Diabetes , vol.32 , pp. 35-45
    • DeFronzo, R.A.1    Ferrannini, E.2    Hendler, R.3    Felig, P.4    Wahren, J.5
  • 29
    • 0026530891 scopus 로고
    • Predominant role of gluconeogenesis in the hepatic glycogen repletion of diabetic rats
    • Giaccari A, Rossetti L: Predominant role of gluconeogenesis in the hepatic glycogen repletion of diabetic rats. J Clin Invest 89:36-45, 1992
    • (1992) J Clin Invest , vol.89 , pp. 36-45
    • Giaccari, A.1    Rossetti, L.2
  • 31
    • 0022467301 scopus 로고
    • Postprandial hyperglycemia in patients with non-insulin-dependent diabetes mellitus
    • Firth RG, Bell PM, Marsh HM, Hansen I, Rizza RA: Postprandial hyperglycemia in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 77: 1525-1532, 1986
    • (1986) J Clin Invest , vol.77 , pp. 1525-1532
    • Firth, R.G.1    Bell, P.M.2    Marsh, H.M.3    Hansen, I.4    Rizza, R.A.5
  • 33
    • 0025066579 scopus 로고
    • Contribution of abnormal muscle and liver glucose metabolism to postprandial hyperglycemia in NIDDM
    • Mitrakou A, Kelley D, Veneman T, Jenssen T, Pangburn T, Reilly J, Gerich J: Contribution of abnormal muscle and liver glucose metabolism to postprandial hyperglycemia in NIDDM. Diabetes 39:1381-1390, 1990
    • (1990) Diabetes , vol.39 , pp. 1381-1390
    • Mitrakou, A.1    Kelley, D.2    Veneman, T.3    Jenssen, T.4    Pangburn, T.5    Reilly, J.6    Gerich, J.7
  • 34
    • 0027967674 scopus 로고
    • Impaired postprandial glucose utilization in non-insulin-dependent diabetes mellitus
    • Kelley D, Mokan M, Veneman T: Impaired postprandial glucose utilization in non-insulin-dependent diabetes mellitus. Metabolism 43:1549-1557, 1994
    • (1994) Metabolism , vol.43 , pp. 1549-1557
    • Kelley, D.1    Mokan, M.2    Veneman, T.3
  • 36
    • 0024332601 scopus 로고
    • Pathways of hepatic glycogen formation in humans following ingestion of a glucose load in the fed state
    • Magnusson I, Chandramouli V, Schumann WC, Kumaran K, Wahren J, Landau BR: Pathways of hepatic glycogen formation in humans following ingestion of a glucose load in the fed state. Metabolism 38:583-585, 1989
    • (1989) Metabolism , vol.38 , pp. 583-585
    • Magnusson, I.1    Chandramouli, V.2    Schumann, W.C.3    Kumaran, K.4    Wahren, J.5    Landau, B.R.6
  • 37
    • 0028926483 scopus 로고
    • Rate of glucose entry into hepatic uridine diphosphoglucose by the direct pathway in fasted and fed states in normal humans
    • Hellerstein MK, Kaempfer S, Reid JS, Wu K, Shackleton CHL Rate of glucose entry into hepatic uridine diphosphoglucose by the direct pathway in fasted and fed states in normal humans. Metabolism 44:172-182, 1995
    • (1995) Metabolism , vol.44 , pp. 172-182
    • Hellerstein, M.K.1    Kaempfer, S.2    Reid, J.S.3    Wu, K.4    Shackleton, C.H.L.5
  • 38
    • 0023629727 scopus 로고
    • Glycoconjugates as noninvasive probes of intrahepatic metabolism. I. Kinetics of label incorporation with evidence of a common precursor UDP-glucose pool for secreted glycoconjugates
    • Hellerstein MK, Greenblatt DJ, Munro HN: Glycoconjugates as noninvasive probes of intrahepatic metabolism. I. Kinetics of label incorporation with evidence of a common precursor UDP-glucose pool for secreted glycoconjugates. Metabolism 36:988-994, 1987
    • (1987) Metabolism , vol.36 , pp. 988-994
    • Hellerstein, M.K.1    Greenblatt, D.J.2    Munro, H.N.3
  • 39
    • 0023200872 scopus 로고
    • Glycoconjugates as noninvasive probes of intrahepatic metabolism. II. Application to measurement of plasma α 1-acid glycoprotein turnover during inflammation
    • Hellerstein MK, Munro HN: Glycoconjugates as noninvasive probes of intrahepatic metabolism. II. Application to measurement of plasma α 1-acid glycoprotein turnover during inflammation. Metabolism 36:995-1000, 1987
    • (1987) Metabolism , vol.36 , pp. 995-1000
    • Hellerstein, M.K.1    Munro, H.N.2
  • 40
  • 42
    • 0028849608 scopus 로고
    • Hepatic glycogen accurately reflected by acetaminophen glucuronide in dogs refed after fasting
    • Rother KI, Schwenk WF: Hepatic glycogen accurately reflected by acetaminophen glucuronide in dogs refed after fasting. Am J Physiol 269:E766-E773, 1995
    • (1995) Am J Physiol , vol.269
    • Rother, K.I.1    Schwenk, W.F.2
  • 43
    • 0019950002 scopus 로고
    • Practical closed-loop insulin delivery: A system for the maintenance of overnight euglycemia and the calculation of basal insulin requirements in insulin-dependent diabetics
    • White NH, Skor D, Santiago JV: Practical closed-loop insulin delivery: a system for the maintenance of overnight euglycemia and the calculation of basal insulin requirements in insulin-dependent diabetics. Ann Intern Med 97:210-213, 1982
    • (1982) Ann Intern Med , vol.97 , pp. 210-213
    • White, N.H.1    Skor, D.2    Santiago, J.V.3
  • 44
    • 0031793982 scopus 로고    scopus 로고
    • Differential regulation of amino acid exchange and protein dynamics across splanchnic and skeletal muscle beds by insulin in healthy human subjects
    • Meek SE, Persson M, Ford GC, Nair KS: Differential regulation of amino acid exchange and protein dynamics across splanchnic and skeletal muscle beds by insulin in healthy human subjects. Diabetes 47:1824-1835, 1998
    • (1998) Diabetes , vol.47 , pp. 1824-1835
    • Meek, S.E.1    Persson, M.2    Ford, G.C.3    Nair, K.S.4
  • 45
    • 0032908594 scopus 로고    scopus 로고
    • Insulin regulation of regional free fatty acid metabolism
    • Meek SE, Nair KS, Jensen MD: Insulin regulation of regional free fatty acid metabolism. Diabetes 48:10-14, 1999
    • (1999) Diabetes , vol.48 , pp. 10-14
    • Meek, S.E.1    Nair, K.S.2    Jensen, M.D.3
  • 46
    • 0024265025 scopus 로고
    • Modeling error and apparent isotope discrimination confound estimation of endogenous glucose production during euglycemic glucose clamps
    • Finegood DT, Bergman RN, Vranic M: Modeling error and apparent isotope discrimination confound estimation of endogenous glucose production during euglycemic glucose clamps. Diabetes 37:1025-1034, 1988
    • (1988) Diabetes , vol.37 , pp. 1025-1034
    • Finegood, D.T.1    Bergman, R.N.2    Vranic, M.3
  • 48
    • 0027417084 scopus 로고
    • Methods for assessment of the rate of onset and offset of insulin action during nonsteady state in humans
    • Butler PC, Caumo A, Zerman A, O'Brien PC, Cobeili C, Rizza RA: Methods for assessment of the rate of onset and offset of insulin action during nonsteady state in humans. Am J Physiol 264:E548-E569, 1993
    • (1993) Am J Physiol , vol.264
    • Butler, P.C.1    Caumo, A.2    Zerman, A.3    O'Brien, P.C.4    Cobeili, C.5    Rizza, R.A.6
  • 49
    • 17744405359 scopus 로고
    • Dose-response characteristics for effects of insulin on production and utilization of glucose in man
    • Rizza RA, Mandarino LJ, Gerich JE: Dose-response characteristics for effects of insulin on production and utilization of glucose in man. Am J Physiol 240:E630-E639, 1981
    • (1981) Am J Physiol , vol.240
    • Rizza, R.A.1    Mandarino, L.J.2    Gerich, J.E.3
  • 50
    • 0028794829 scopus 로고
    • Measurement of abdominal and visceral fat with computed tomography and dual-energy X-ray absorptiometry
    • Jensen MD, Kanaley JA, Reed JE, Sheedy PF: Measurement of abdominal and visceral fat with computed tomography and dual-energy X-ray absorptiometry. Am J Clin Nutr 61:274-278, 1995
    • (1995) Am J Clin Nutr , vol.61 , pp. 274-278
    • Jensen, M.D.1    Kanaley, J.A.2    Reed, J.E.3    Sheedy, P.F.4
  • 52
  • 55
    • 0027199061 scopus 로고
    • Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats
    • Rossetti L, Giaccari A, Barzilai N, Howard K, Sebel G, Hu M: Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. J Clin Invest 92:1126-1134, 1993
    • (1993) J Clin Invest , vol.92 , pp. 1126-1134
    • Rossetti, L.1    Giaccari, A.2    Barzilai, N.3    Howard, K.4    Sebel, G.5    Hu, M.6
  • 56
    • 0030765908 scopus 로고    scopus 로고
    • Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat
    • Goodpaster BH, Thaete FL, Simoneau J-A, Kelley DE: Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 46:1579-1585, 1997
    • (1997) Diabetes , vol.46 , pp. 1579-1585
    • Goodpaster, B.H.1    Thaete, F.L.2    Simoneau, J.-A.3    Kelley, D.E.4
  • 59
    • 0029874313 scopus 로고    scopus 로고
    • Abdominal fat and insulin resistance in normal and overweight women: Direct measurements reveal a strong relationship in subjects at both low and high risk of NIDDM
    • Carey DG, Jenkins AB, Campbell LV, Freund J, Chisholm DJ: Abdominal fat and insulin resistance in normal and overweight women: direct measurements reveal a strong relationship in subjects at both low and high risk of NIDDM. Diabetes 45:633-638, 1996
    • (1996) Diabetes , vol.45 , pp. 633-638
    • Carey, D.G.1    Jenkins, A.B.2    Campbell, L.V.3    Freund, J.4    Chisholm, D.J.5
  • 60
    • 0029862540 scopus 로고    scopus 로고
    • Relationship of generalized and regional adiposity to insulin sensitivity in men with NIDDM
    • Abate N, Garg A, Reshock RM, Stray-Gundersen J, Adams-Huet B, Grundy SM: Relationship of generalized and regional adiposity to insulin sensitivity in men with NIDDM. Diabetes 45:1684-1693, 1996
    • (1996) Diabetes , vol.45 , pp. 1684-1693
    • Abate, N.1    Garg, A.2    Reshock, R.M.3    Stray-Gundersen, J.4    Adams-Huet, B.5    Grundy, S.M.6
  • 61
    • 0024403750 scopus 로고
    • Basal-rate intravenous insulin infusion compared to conventional insulin treatment in patients with type II diabetes: Aprospective crossover trial
    • Blackshear PJ, Roussell AM, Cohen AM, Nathan DM: Basal-rate intravenous insulin infusion compared to conventional insulin treatment in patients with type II diabetes: aprospective crossover trial. Diabetes Care 12:455-463, 1989
    • (1989) Diabetes Care , vol.12 , pp. 455-463
    • Blackshear, P.J.1    Roussell, A.M.2    Cohen, A.M.3    Nathan, D.M.4
  • 62
    • 0018821716 scopus 로고
    • Effect of prolonged glyclazide treatment on blood glucose and plasma insulin responses in obese patients with maturity-onset diabetes
    • Wajchenberg BL, Nery M, Lerne CE, Silveira AA, Fioratti P, Germek OA: Effect of prolonged glyclazide treatment on blood glucose and plasma insulin responses in obese patients with maturity-onset diabetes. Clin Pharmacol Ther 27:375-378, 1980
    • (1980) Clin Pharmacol Ther , vol.27 , pp. 375-378
    • Wajchenberg, B.L.1    Nery, M.2    Lerne, C.E.3    Silveira, A.A.4    Fioratti, P.5    Germek, O.A.6
  • 64
    • 0019292969 scopus 로고
    • The effect of glibenclamide on the glucose and insulin profile in maturity-onset diabetics following both acute and long-term treatment
    • Owens DR, Biggs PI, Shetty KJ, Wragg KG: The effect of glibenclamide on the glucose and insulin profile in maturity-onset diabetics following both acute and long-term treatment. Diabetes Metab 6:219-224, 1980
    • (1980) Diabetes Metab , vol.6 , pp. 219-224
    • Owens, D.R.1    Biggs, P.I.2    Shetty, K.J.3    Wragg, K.G.4
  • 65
    • 0021987499 scopus 로고
    • Regulation of hepatic glycogen metabolism: Effects of diabetes, insulin infusion, and pancreatic islet transplantation
    • Margolis RN, Selawry HP, Curnow RT: Regulation of hepatic glycogen metabolism: effects of diabetes, insulin infusion, and pancreatic islet transplantation. Metabolism 34:62-68, 1985
    • (1985) Metabolism , vol.34 , pp. 62-68
    • Margolis, R.N.1    Selawry, H.P.2    Curnow, R.T.3
  • 66
    • 0018427362 scopus 로고
    • Glucose activation of liver glycogen synthase
    • Miller TB Jr: Glucose activation of liver glycogen synthase. Biochim Biophys Acta 583:36-46, 1978
    • (1978) Biochim Biophys Acta , vol.583 , pp. 36-46
    • Miller T.B., Jr.1
  • 67
    • 0016834286 scopus 로고
    • Glycogen synthesis in the perfused liver of streptozotocin-diabetic rats
    • Whitton PD, Hems DA: Glycogen synthesis in the perfused liver of streptozotocin-diabetic rats. Biochem J 150:153-165, 1975
    • (1975) Biochem J , vol.150 , pp. 153-165
    • Whitton, P.D.1    Hems, D.A.2
  • 68
    • 0031728154 scopus 로고    scopus 로고
    • Overnight normalization of glucose concentrations improves hepatic but not extrahepatic insulin action in subjects with type 2 diabetes mellitus
    • Wise SD, Nielson MF, Cryer PE, Rizza RA: Overnight normalization of glucose concentrations improves hepatic but not extrahepatic insulin action in subjects with type 2 diabetes mellitus. J Clin Endocrinol Metab 83:2461-2469, 1998
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2461-2469
    • Wise, S.D.1    Nielson, M.F.2    Cryer, P.E.3    Rizza, R.A.4
  • 69
    • 0032969116 scopus 로고    scopus 로고
    • Contributions by kidney and liver to glucose production in the postabsorptive state and after 60 h of fasting
    • Ekberg K, Landau BR, Wajngot A, Chandraniouli V, Efendic S, Brunengraber H, Wahren J: Contributions by kidney and liver to glucose production in the postabsorptive state and after 60 h of fasting. Diabetes 48:292-298, 1999
    • (1999) Diabetes , vol.48 , pp. 292-298
    • Ekberg, K.1    Landau, B.R.2    Wajngot, A.3    Chandraniouli, V.4    Efendic, S.5    Brunengraber, H.6    Wahren, J.7
  • 71
    • 0028276676 scopus 로고
    • Insulin regulation of renal glucose metabolism in conscious dogs
    • Cersosimo E, Judd RL, Miles JM: Insulin regulation of renal glucose metabolism in conscious dogs. J Clin Invest 93:2584-2589, 1994
    • (1994) J Clin Invest , vol.93 , pp. 2584-2589
    • Cersosimo, E.1    Judd, R.L.2    Miles, J.M.3
  • 72
    • 0021713260 scopus 로고
    • The glucose paradox: Is glucose a substrate for liver metabolism?
    • Katz J, McGarry JD: The glucose paradox: is glucose a substrate for liver metabolism? J Clin Invest 74:1901-1909, 1984
    • (1984) J Clin Invest , vol.74 , pp. 1901-1909
    • Katz, J.1    McGarry, J.D.2
  • 75
    • 0027537082 scopus 로고
    • Phlorizin treatment of diabetic rats partially reverses the abnormal expression of genes involved in hepatic glucose metabolism
    • Brichard SM, Henquin JC, Girard J: Phlorizin treatment of diabetic rats partially reverses the abnormal expression of genes involved in hepatic glucose metabolism. Diabetologia 36:292-298, 1993
    • (1993) Diabetologia , vol.36 , pp. 292-298
    • Brichard, S.M.1    Henquin, J.C.2    Girard, J.3
  • 76
    • 0026454282 scopus 로고
    • Evidence that GLUT-2 mRNA and protein concentrations are decreased by hyperinsulinaemia and increased by hyperglycaemia in liver of diabetic rats
    • Burcelin R, Eddouks M, Kande J, Assan R, Girard J: Evidence that GLUT-2 mRNA and protein concentrations are decreased by hyperinsulinaemia and increased by hyperglycaemia in liver of diabetic rats. Biochem J 288:675-679, 1992
    • (1992) Biochem J , vol.288 , pp. 675-679
    • Burcelin, R.1    Eddouks, M.2    Kande, J.3    Assan, R.4    Girard, J.5
  • 78
    • 0028152377 scopus 로고
    • Facultative glucose transporters
    • Mueckler M: Facultative glucose transporters. Eur J Biochem 219:713-725, 1994
    • (1994) Eur J Biochem , vol.219 , pp. 713-725
    • Mueckler, M.1
  • 81
    • 0028946262 scopus 로고
    • Glucokinase and cytosolic phosphoenolpyruvate carboxykinase (GTP) in the human liver: Regulation of gene expression in cultured hepatocytes
    • Iynegjian PB, Marie S, Gjinovici A, Genin B, Deng S-P, Buhler L, Morel P, Mentha G: Glucokinase and cytosolic phosphoenolpyruvate carboxykinase (GTP) in the human liver: regulation of gene expression in cultured hepatocytes. J Clin Invest 95:1966-1973, 1995
    • (1995) J Clin Invest , vol.95 , pp. 1966-1973
    • Iynegjian, P.B.1    Marie, S.2    Gjinovici, A.3    Genin, B.4    Deng, S.-P.5    Buhler, L.6    Morel, P.7    Mentha, G.8
  • 84
    • 0030987889 scopus 로고    scopus 로고
    • High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect
    • Zierath JR, Houseknecht KL, Gnudi L, Kahn BB: High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect. Diabetes 46:215-223, 1997
    • (1997) Diabetes , vol.46 , pp. 215-223
    • Zierath, J.R.1    Houseknecht, K.L.2    Gnudi, L.3    Kahn, B.B.4


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