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Volumn 285, Issue 2, 2011, Pages 91-100

Pleiotropic corepressors Sin3 and Ssn6 interact with repressor Opi1 and negatively regulate transcription of genes required for phospholipid biosynthesis in the yeast Saccharomyces cerevisiae

Author keywords

Opi1; Phospholipid biosynthesis; Saccharomyces cerevisiae; Sin3; Ssn6; Transcriptional corepressor

Indexed keywords

COREPRESSOR PROTEIN; PROTEIN INO2; PROTEIN OPI1; PROTEIN SIN3; PROTEIN SSN6; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 79551592413     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-010-0589-5     Document Type: Article
Times cited : (16)

References (62)
  • 1
    • 0028363566 scopus 로고
    • INO2 and INO4 gene products, positive regulators of phospholipid biosynthesis in Saccharomyces cerevisiae, form a complex that binds to the INO1 promoter
    • 1:CAS:528:DyaK2cXkt1yms7s%3D 8195172
    • J Ambroziak SA Henry 1994 INO2 and INO4 gene products, positive regulators of phospholipid biosynthesis in Saccharomyces cerevisiae, form a complex that binds to the INO1 promoter J Biol Chem 269 15344 15349 1:CAS:528:DyaK2cXkt1yms7s%3D 8195172
    • (1994) J Biol Chem , vol.269 , pp. 15344-15349
    • Ambroziak, J.1    Henry, S.A.2
  • 2
    • 15244341978 scopus 로고    scopus 로고
    • Nrg1 and Nrg2 transcriptional repressors are differently regulated in response to carbon source
    • 1:CAS:528:DC%2BD2cXjtlKru7s%3D 10.1128/EC.3.2.311-317.2004 15075261
    • CD Berkey VK Vyas M Carlson 2004 Nrg1 and Nrg2 transcriptional repressors are differently regulated in response to carbon source Eukaryot Cell 3 311 317 1:CAS:528:DC%2BD2cXjtlKru7s%3D 10.1128/EC.3.2.311-317.2004 15075261
    • (2004) Eukaryot Cell , vol.3 , pp. 311-317
    • Berkey, C.D.1    Vyas, V.K.2    Carlson, M.3
  • 3
    • 0344496513 scopus 로고    scopus 로고
    • The tetratricopeptide repeat: A structural motif mediating protein-protein interactions
    • 1:STN:280:DyaK1MvkslChtQ%3D%3D 10.1002/(SICI)1521-1878(199911)21: 11<932::AID-BIES5>3.0.CO;2-N 10517866
    • GL Blatch M Lässle 1999 The tetratricopeptide repeat: a structural motif mediating protein-protein interactions Bioessays 21 932 939 1:STN:280:DyaK1MvkslChtQ%3D%3D 10.1002/(SICI)1521-1878(199911)21:11<932::AID- BIES5>3.0.CO;2-N 10517866
    • (1999) Bioessays , vol.21 , pp. 932-939
    • Blatch, G.L.1    Lässle, M.2
  • 4
    • 0033696968 scopus 로고    scopus 로고
    • Solution structure of the interacting domains of the Mad-Sin3 complex: Implications for recruitment of a chromatin-modifying complex
    • 1:CAS:528:DC%2BD3cXot1Gmsr4%3D 10.1016/S0092-8674(00)00168-9 11106735
    • K Brubaker SM Cowley K Huang L Loo GS Yochum DE Ayer RN Eisenman I Radhakrishnan 2000 Solution structure of the interacting domains of the Mad-Sin3 complex: implications for recruitment of a chromatin-modifying complex Cell 103 655 665 1:CAS:528:DC%2BD3cXot1Gmsr4%3D 10.1016/S0092-8674(00)00168-9 11106735
    • (2000) Cell , vol.103 , pp. 655-665
    • Brubaker, K.1    Cowley, S.M.2    Huang, K.3    Loo, L.4    Yochum, G.S.5    Ayer, D.E.6    Eisenman, R.N.7    Radhakrishnan, I.8
  • 6
    • 27744577727 scopus 로고    scopus 로고
    • Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription
    • 1:CAS:528:DC%2BD2MXht1yktrvL 10.1016/j.cell.2005.10.023 16286007
    • MJ Carrozza B Li L Florens T Suganuma SK Swanson KK Lee WJ Shia S Anderson J Yates MP Washburn JL Workman 2005 Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription Cell 123 581 592 1:CAS:528:DC%2BD2MXht1yktrvL 10.1016/j.cell.2005.10.023 16286007
    • (2005) Cell , vol.123 , pp. 581-592
    • Carrozza, M.J.1    Li, B.2    Florens, L.3    Suganuma, T.4    Swanson, S.K.5    Lee, K.K.6    Shia, W.J.7    Anderson, S.8    Yates, J.9    Washburn, M.P.10    Workman, J.L.11
  • 7
    • 33947201241 scopus 로고    scopus 로고
    • Transcriptional regulation of yeast phospholipid biosynthetic genes
    • 1:CAS:528:DC%2BD2sXjsVerurk%3D 16854618
    • M Chen LC Hancock JM Lopes 2007 Transcriptional regulation of yeast phospholipid biosynthetic genes Biochim Biophys Acta 1771 310 321 1:CAS:528:DC%2BD2sXjsVerurk%3D 16854618
    • (2007) Biochim Biophys Acta , vol.1771 , pp. 310-321
    • Chen, M.1    Hancock, L.C.2    Lopes, J.M.3
  • 8
    • 0035933333 scopus 로고    scopus 로고
    • Sfl1 functions via the co-repressor Ssn6-Tup1 and the cAMP-dependent protein kinase Tpk2
    • 1:CAS:528:DC%2BD3MXkt1Sgtro%3D 10.1006/jmbi.2001.4742 11399075
    • RS Conlan D Tzamarias 2001 Sfl1 functions via the co-repressor Ssn6-Tup1 and the cAMP-dependent protein kinase Tpk2 J Mol Biol 309 1007 1015 1:CAS:528:DC%2BD3MXkt1Sgtro%3D 10.1006/jmbi.2001.4742 11399075
    • (2001) J Mol Biol , vol.309 , pp. 1007-1015
    • Conlan, R.S.1    Tzamarias, D.2
  • 9
    • 0344628648 scopus 로고    scopus 로고
    • TPR proteins: The versatile helix
    • 10.1016/j.tibs.2003.10.007 14659697
    • LD D'Andrea L Regan 2003 TPR proteins: the versatile helix Trends Biochem Sci 28 655 662 10.1016/j.tibs.2003.10.007 14659697
    • (2003) Trends Biochem Sci , vol.28 , pp. 655-662
    • D'Andrea, L.D.1    Regan, L.2
  • 10
    • 0348010365 scopus 로고    scopus 로고
    • Tup1-Ssn6 interacts with multiple class i histone deacetylases in vivo
    • 1:CAS:528:DC%2BD3sXpslSqsLg%3D 10.1074/jbc.M309753200 14525981
    • JK Davie DG Edmondson CB Coco SY Dent 2003 Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo J Biol Chem 278 50158 50162 1:CAS:528:DC%2BD3sXpslSqsLg%3D 10.1074/jbc.M309753200 14525981
    • (2003) J Biol Chem , vol.278 , pp. 50158-50162
    • Davie, J.K.1    Edmondson, D.G.2    Coco, C.B.3    Dent, S.Y.4
  • 11
    • 0030003051 scopus 로고    scopus 로고
    • Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4
    • 1:CAS:528:DyaK28XjtlCnu7w%3D 10.1101/gad.10.10.1247 8675011
    • DG Edmondson MM Smith SY Roth 1996 Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4 Genes Dev 10 1247 1259 1:CAS:528:DyaK28XjtlCnu7w%3D 10.1101/gad.10.10.1247 8675011
    • (1996) Genes Dev , vol.10 , pp. 1247-1259
    • Edmondson, D.G.1    Smith, M.M.2    Roth, S.Y.3
  • 12
    • 1542290663 scopus 로고    scopus 로고
    • Nhp6 facilitates Aft1 binding and Ssn6 recruitment, both essential for FRE2 transcriptional activation
    • 1:CAS:528:DC%2BD2cXhtVeqsLo%3D 10.1038/sj.emboj.7600043 14739928
    • GS Fragiadakis D Tzamarias D Alexandraki 2004 Nhp6 facilitates Aft1 binding and Ssn6 recruitment, both essential for FRE2 transcriptional activation EMBO J 23 333 342 1:CAS:528:DC%2BD2cXhtVeqsLo%3D 10.1038/sj.emboj.7600043 14739928
    • (2004) EMBO J , vol.23 , pp. 333-342
    • Fragiadakis, G.S.1    Tzamarias, D.2    Alexandraki, D.3
  • 13
    • 24744435397 scopus 로고    scopus 로고
    • Mammalian Groucho homologs: Redundancy or specificity?
    • 1:CAS:528:DC%2BD2MXlslWqu7c%3D 10.1002/jcb.20476 15861397
    • M Gasperowicz F Otto 2005 Mammalian Groucho homologs: redundancy or specificity? J Cell Biochem 95 670 687 1:CAS:528:DC%2BD2MXlslWqu7c%3D 10.1002/jcb.20476 15861397
    • (2005) J Cell Biochem , vol.95 , pp. 670-687
    • Gasperowicz, M.1    Otto, F.2
  • 14
    • 0024266139 scopus 로고
    • New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
    • 1:CAS:528:DyaL1MXhs1OntL0%3D 10.1016/0378-1119(88)90185-0 3073106
    • RD Gietz A Sugino 1988 New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites Gene 74 527 534 1:CAS:528:DyaL1MXhs1OntL0%3D 10.1016/0378-1119(88)90185-0 3073106
    • (1988) Gene , vol.74 , pp. 527-534
    • Gietz, R.D.1    Sugino, A.2
  • 15
    • 0034604062 scopus 로고    scopus 로고
    • Identification of residues in the TPR domain of Ssn6 responsible for interaction with the Tup1 protein
    • 1:CAS:528:DC%2BD3cXivVGnsrY%3D 10.1016/S0014-5793(00)01480-0 10802055
    • N Gounalaki D Tzamarias M Vlassi 2000 Identification of residues in the TPR domain of Ssn6 responsible for interaction with the Tup1 protein FEBS Lett 473 37 41 1:CAS:528:DC%2BD3cXivVGnsrY%3D 10.1016/S0014-5793(00)01480-0 10802055
    • (2000) FEBS Lett , vol.473 , pp. 37-41
    • Gounalaki, N.1    Tzamarias, D.2    Vlassi, M.3
  • 16
    • 2342461648 scopus 로고    scopus 로고
    • Applicability of tandem affinity purification MudPIT to pathway proteomics in yeast
    • 1:CAS:528:DC%2BD2cXisFWhsb0%3D 10.1074/mcp.M300099-MCP200 14660704
    • J Graumann LA Dunipace JH Seol WH McDonald JR Yates 3rd BJ Wold RJ Deshaies 2004 Applicability of tandem affinity purification MudPIT to pathway proteomics in yeast Mol Cell Proteomics 3 226 237 1:CAS:528:DC%2BD2cXisFWhsb0%3D 10.1074/mcp.M300099-MCP200 14660704
    • (2004) Mol Cell Proteomics , vol.3 , pp. 226-237
    • Graumann, J.1    Dunipace, L.A.2    Seol, J.H.3    McDonald, W.H.4    Yates III, J.R.5    Wold, B.J.6    Deshaies, R.J.7
  • 17
    • 4344672753 scopus 로고    scopus 로고
    • Promoter-dependent roles for the Srb10 cyclin dependent kinase and the Hda1 deacetylase in Tup1-mediated repression in Saccharomyces cerevisiae
    • 1:CAS:528:DC%2BD2cXnt1eksbY%3D 10.1091/mbc.E04-05-0412 15240822
    • SR Green AD Johnson 2004 Promoter-dependent roles for the Srb10 cyclin dependent kinase and the Hda1 deacetylase in Tup1-mediated repression in Saccharomyces cerevisiae Mol Biol Cell 15 4191 4202 1:CAS:528: DC%2BD2cXnt1eksbY%3D 10.1091/mbc.E04-05-0412 15240822
    • (2004) Mol Biol Cell , vol.15 , pp. 4191-4202
    • Green, S.R.1    Johnson, A.D.2
  • 18
    • 69449089064 scopus 로고    scopus 로고
    • Sin3: Master scaffold and transcriptional corepressor
    • 1:CAS:528:DC%2BD1MXhtV2ksrrK 19505602
    • A Grzenda G Lomberk JS Zhang R Urrutia 2009 Sin3: master scaffold and transcriptional corepressor Biochim Biophys Acta 1789 443 450 1:CAS:528:DC%2BD1MXhtV2ksrrK 19505602
    • (2009) Biochim Biophys Acta , vol.1789 , pp. 443-450
    • Grzenda, A.1    Lomberk, G.2    Zhang, J.S.3    Urrutia, R.4
  • 19
    • 17644419063 scopus 로고    scopus 로고
    • Constitutive expression of yeast phospholipid biosynthetic genes by variants of Ino2 activator defective for interaction with Opi1 repressor
    • 1:CAS:528:DC%2BD2MXjvVGlt7k%3D 10.1111/j.1365-2958.2004.04499.x 15819625
    • WT Heyken A Repenning J Kumme HJ Schüller 2005 Constitutive expression of yeast phospholipid biosynthetic genes by variants of Ino2 activator defective for interaction with Opi1 repressor Mol Microbiol 56 696 707 1:CAS:528:DC%2BD2MXjvVGlt7k%3D 10.1111/j.1365-2958.2004.04499.x 15819625
    • (2005) Mol Microbiol , vol.56 , pp. 696-707
    • Heyken, W.T.1    Repenning, A.2    Kumme, J.3    Schüller, H.J.4
  • 21
    • 0028040191 scopus 로고
    • A pleiotropic phospholipid biosynthetic regulatory mutation in Saccharomyces cerevisiae is allelic to sin3 (sdi1, ume4, rpd1)
    • 1:CAS:528:DyaK2cXktVCrtbw%3D 8150277
    • KA Hudak JM Lopes SA Henry 1994 A pleiotropic phospholipid biosynthetic regulatory mutation in Saccharomyces cerevisiae is allelic to sin3 (sdi1, ume4, rpd1) Genetics 136 475 483 1:CAS:528:DyaK2cXktVCrtbw%3D 8150277
    • (1994) Genetics , vol.136 , pp. 475-483
    • Hudak, K.A.1    Lopes, J.M.2    Henry, S.A.3
  • 22
    • 0030455820 scopus 로고    scopus 로고
    • Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
    • 1:CAS:528:DyaK2sXkslyhsw%3D%3D 8978031
    • P James J Halladay EA Craig 1996 Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast Genetics 144 1425 1436 1:CAS:528:DyaK2sXkslyhsw%3D%3D 8978031
    • (1996) Genetics , vol.144 , pp. 1425-1436
    • James, P.1    Halladay, J.2    Craig, E.A.3
  • 23
    • 0037241720 scopus 로고    scopus 로고
    • N-CoR-HDAC corepressor complexes: Roles in transcriptional regulation by nuclear hormone receptors
    • 1:CAS:528:DC%2BD3sXitVClurs%3D 12596910
    • PL Jones YB Shi 2003 N-CoR-HDAC corepressor complexes: roles in transcriptional regulation by nuclear hormone receptors Curr Top Microbiol Immunol 274 237 268 1:CAS:528:DC%2BD3sXitVClurs%3D 12596910
    • (2003) Curr Top Microbiol Immunol , vol.274 , pp. 237-268
    • Jones, P.L.1    Shi, Y.B.2
  • 24
    • 31044431992 scopus 로고    scopus 로고
    • Analysis of Opi1p repressor mutants
    • 1:CAS:528:DC%2BD2MXhtlSnt77J 10.1007/s00294-005-0021-6 16322993
    • MR Kaadige JM Lopes 2006 Analysis of Opi1p repressor mutants Curr Genet 49 30 38 1:CAS:528:DC%2BD2MXhtlSnt77J 10.1007/s00294-005-0021-6 16322993
    • (2006) Curr Genet , vol.49 , pp. 30-38
    • Kaadige, M.R.1    Lopes, J.M.2
  • 25
    • 0343924289 scopus 로고    scopus 로고
    • Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters
    • 1:CAS:528:DyaK2sXjtFWmu7w%3D 10.1016/S0092-8674(00)80217-2 9150136
    • D Kadosh K Struhl 1997 Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters Cell 89 365 371 1:CAS:528:DyaK2sXjtFWmu7w%3D 10.1016/S0092-8674(00) 80217-2 9150136
    • (1997) Cell , vol.89 , pp. 365-371
    • Kadosh, D.1    Struhl, K.2
  • 26
    • 0026571899 scopus 로고
    • Ssn6-Tup1 is a general repressor of transcription in yeast
    • 1:CAS:528:DyaK38Xhs1Oktbc%3D 10.1016/0092-8674(92)90146-4 1739976
    • CA Keleher MJ Redd J Schultz M Carlson AD Johnson 1992 Ssn6-Tup1 is a general repressor of transcription in yeast Cell 68 709 719 1:CAS:528: DyaK38Xhs1Oktbc%3D 10.1016/0092-8674(92)90146-4 1739976
    • (1992) Cell , vol.68 , pp. 709-719
    • Keleher, C.A.1    Redd, M.J.2    Schultz, J.3    Carlson, M.4    Johnson, A.D.5
  • 28
    • 48749114997 scopus 로고    scopus 로고
    • A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation
    • 1:CAS:528:DC%2BD1cXpslKqsbo%3D 10.1101/gad.1679508 18676811
    • YY Lin Y Qi JY Lu X Pan DS Yuan Y Zhao JS Bader JD Boeke 2008 A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation Genes Dev 22 2062 2074 1:CAS:528: DC%2BD1cXpslKqsbo%3D 10.1101/gad.1679508 18676811
    • (2008) Genes Dev , vol.22 , pp. 2062-2074
    • Lin, Y.Y.1    Qi, Y.2    Lu, J.Y.3    Pan, X.4    Yuan, D.S.5    Zhao, Y.6    Bader, J.S.7    Boeke, J.D.8
  • 29
    • 40649113050 scopus 로고    scopus 로고
    • Groucho/Tup1 family co-repressors in plant development
    • 1:CAS:528:DC%2BD1cXjtl2ltrw%3D 10.1016/j.tplants.2007.12.005 18314376
    • Z Liu V Karmarkar 2008 Groucho/Tup1 family co-repressors in plant development Trends Plant Sci 13 137 144 1:CAS:528:DC%2BD1cXjtl2ltrw%3D 10.1016/j.tplants.2007.12.005 18314376
    • (2008) Trends Plant Sci , vol.13 , pp. 137-144
    • Liu, Z.1    Karmarkar, V.2
  • 30
    • 2942677427 scopus 로고    scopus 로고
    • Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid
    • 1:CAS:528:DC%2BD2cXks1Chu7w%3D 10.1126/science.1096083 15192221
    • CJ Loewen ML Gaspar SA Jesch C Delon NT Ktistakis SA Henry TP Levine 2004 Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid Science 304 1644 1647 1:CAS:528:DC%2BD2cXks1Chu7w%3D 10.1126/science.1096083 15192221
    • (2004) Science , vol.304 , pp. 1644-1647
    • Loewen, C.J.1    Gaspar, M.L.2    Jesch, S.A.3    Delon, C.4    Ktistakis, N.T.5    Henry, S.A.6    Levine, T.P.7
  • 31
    • 33750684669 scopus 로고    scopus 로고
    • Transcriptional repression by Tup1-Ssn6
    • 10.1139/O06-073 16936817
    • TM Malavé SY Dent 2006 Transcriptional repression by Tup1-Ssn6 Biochem Cell Biol 84 437 443 10.1139/O06-073 16936817
    • (2006) Biochem Cell Biol , vol.84 , pp. 437-443
    • Malavé, T.M.1    Dent, S.Y.2
  • 32
    • 55949085986 scopus 로고    scopus 로고
    • Keeping things quiet: Roles of NuRD and Sin3 co-repressor complexes during mammalian development
    • 1:CAS:528:DC%2BD1cXhsVWnu7%2FP 10.1016/j.biocel.2008.07.022 18775506
    • P McDonel I Costello B Hendrich 2009 Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development Int J Biochem Cell Biol 41 108 116 1:CAS:528:DC%2BD1cXhsVWnu7%2FP 10.1016/j.biocel.2008.07.022 18775506
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 108-116
    • McDonel, P.1    Costello, I.2    Hendrich, B.3
  • 33
    • 0028586017 scopus 로고
    • Regulatable promoters of Saccharomyces cerevisiae: Comparison of transcriptional activity and their use for heterologous expression
    • 1:CAS:528:DyaK2MXjtlGit74%3D 10.1093/nar/22.25.5767 7838736
    • D Mumberg R Müller M Funk 1994 Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression Nucleic Acids Res 22 5767 5768 1:CAS:528: DyaK2MXjtlGit74%3D 10.1093/nar/22.25.5767 7838736
    • (1994) Nucleic Acids Res , vol.22 , pp. 5767-5768
    • Mumberg, D.1    Müller, R.2    Funk, M.3
  • 34
    • 0036298418 scopus 로고    scopus 로고
    • Cti6, a PHD domain protein, bridges the Cyc8-Tup1 corepressor and the SAGA coactivator to overcome repression at GAL1
    • 1:CAS:528:DC%2BD38Xlt1Sktro%3D 10.1016/S1097-2765(02)00545-2 12086626
    • M Papamichos-Chronakis T Petrakis E Ktistaki I Topalidou D Tzamarias 2002 Cti6, a PHD domain protein, bridges the Cyc8-Tup1 corepressor and the SAGA coactivator to overcome repression at GAL1 Mol Cell 9 1297 1305 1:CAS:528:DC%2BD38Xlt1Sktro%3D 10.1016/S1097-2765(02)00545-2 12086626
    • (2002) Mol Cell , vol.9 , pp. 1297-1305
    • Papamichos-Chronakis, M.1    Petrakis, T.2    Ktistaki, E.3    Topalidou, I.4    Tzamarias, D.5
  • 35
    • 15544364487 scopus 로고    scopus 로고
    • How the Rgt1 transcription factor of Saccharomyces cerevisiae is regulated by glucose
    • 1:CAS:528:DC%2BD2MXjtVOmtbg%3D 10.1534/genetics.104.034512 15489524
    • JA Polish JH Kim M Johnston 2005 How the Rgt1 transcription factor of Saccharomyces cerevisiae is regulated by glucose Genetics 169 583 594 1:CAS:528:DC%2BD2MXjtVOmtbg%3D 10.1534/genetics.104.034512 15489524
    • (2005) Genetics , vol.169 , pp. 583-594
    • Polish, J.A.1    Kim, J.H.2    Johnston, M.3
  • 36
    • 0036289351 scopus 로고    scopus 로고
    • Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress
    • 1:CAS:528:DC%2BD38Xlt1Sktrs%3D 10.1016/S1097-2765(02)00557-9 12086627
    • M Proft K Struhl 2002 Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress Mol Cell 9 1307 1317 1:CAS:528:DC%2BD38Xlt1Sktrs%3D 10.1016/S1097- 2765(02)00557-9 12086627
    • (2002) Mol Cell , vol.9 , pp. 1307-1317
    • Proft, M.1    Struhl, K.2
  • 37
    • 3142764646 scopus 로고    scopus 로고
    • Cti6 is an Rpd3-Sin3 histone deacetylase associated protein required for growth under iron-limiting conditions in Saccharomyces cerevisiae
    • 1:CAS:528:DC%2BD2cXlsFKiur4%3D 10.1074/jbc.M313463200 15133041
    • S Puig M Lau DJ Thiele 2004 Cti6 is an Rpd3-Sin3 histone deacetylase associated protein required for growth under iron-limiting conditions in Saccharomyces cerevisiae J Biol Chem 279 30298 30306 1:CAS:528: DC%2BD2cXlsFKiur4%3D 10.1074/jbc.M313463200 15133041
    • (2004) J Biol Chem , vol.279 , pp. 30298-30306
    • Puig, S.1    Lau, M.2    Thiele, D.J.3
  • 38
    • 37549011826 scopus 로고    scopus 로고
    • Conserved themes in target recognition by the PAH1 and PAH2 domains of the Sin3 transcriptional corepressor
    • 1:CAS:528:DC%2BD1cXlsFyjsQ%3D%3D 10.1016/j.jmb.2007.11.079 18089292
    • SC Sahu KA Swanson RS Kang K Huang K Brubaker K Ratcliff I Radhakrishnan 2008 Conserved themes in target recognition by the PAH1 and PAH2 domains of the Sin3 transcriptional corepressor J Mol Biol 375 1444 1456 1:CAS:528: DC%2BD1cXlsFyjsQ%3D%3D 10.1016/j.jmb.2007.11.079 18089292
    • (2008) J Mol Biol , vol.375 , pp. 1444-1456
    • Sahu, S.C.1    Swanson, K.A.2    Kang, R.S.3    Huang, K.4    Brubaker, K.5    Ratcliff, K.6    Radhakrishnan, I.7
  • 39
    • 3042680942 scopus 로고    scopus 로고
    • The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase
    • 10.1038/sj.emboj.7600233 15141165
    • M Schröder R Clark CY Liu RJ Kaufman 2004 The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase EMBO J 23 2281 2292 10.1038/sj.emboj.7600233 15141165
    • (2004) EMBO J , vol.23 , pp. 2281-2292
    • Schröder, M.1    Clark, R.2    Liu, C.Y.3    Kaufman, R.J.4
  • 40
    • 0026529044 scopus 로고
    • Coordinate genetic control of yeast fatty acid synthase genes FAS1 and FAS2 by an upstream activation site common to genes involved in membrane lipid biosynthesis
    • 1740101
    • HJ Schüller A Hahn F Tröster A Schütz E Schweizer 1992 Coordinate genetic control of yeast fatty acid synthase genes FAS1 and FAS2 by an upstream activation site common to genes involved in membrane lipid biosynthesis EMBO J 11 107 114 1740101
    • (1992) EMBO J , vol.11 , pp. 107-114
    • Schüller, H.J.1    Hahn, A.2    Tröster, F.3    Schütz, A.4    Schweizer, E.5
  • 41
    • 0028963304 scopus 로고
    • Yeast transcriptional activator INO2 interacts as an Ino2p/Ino4p basic helix-loop-helix heteromeric complex with the inositol/choline-responsive element necessary for expression of phospholipid biosynthetic genes in Saccharomyces cerevisiae
    • 1:CAS:528:DyaK2MXjvFemsL4%3D 10.1093/nar/23.2.230 7862526
    • S Schwank R Ebbert K Rautenstrauss E Schweizer HJ Schüller 1995 Yeast transcriptional activator INO2 interacts as an Ino2p/Ino4p basic helix-loop-helix heteromeric complex with the inositol/choline-responsive element necessary for expression of phospholipid biosynthetic genes in Saccharomyces cerevisiae Nucleic Acids Res 23 230 237 1:CAS:528: DyaK2MXjvFemsL4%3D 10.1093/nar/23.2.230 7862526
    • (1995) Nucleic Acids Res , vol.23 , pp. 230-237
    • Schwank, S.1    Ebbert, R.2    Rautenstrauss, K.3    Schweizer, E.4    Schüller, H.J.5
  • 42
    • 0029074187 scopus 로고
    • SIN3 works through two different promoter elements to regulate INO1 gene expression in yeast
    • 1:CAS:528:DyaK2MXms1eksbo%3D 10.1093/nar/23.11.1964 7596825
    • KH Slekar SA Henry 1995 SIN3 works through two different promoter elements to regulate INO1 gene expression in yeast Nucleic Acids Res 23 1964 1969 1:CAS:528:DyaK2MXms1eksbo%3D 10.1093/nar/23.11.1964 7596825
    • (1995) Nucleic Acids Res , vol.23 , pp. 1964-1969
    • Slekar, K.H.1    Henry, S.A.2
  • 43
    • 0034635988 scopus 로고    scopus 로고
    • A sequence resembling a peroxisomal targeting sequence directs the interaction between the tetratricopeptide repeats of Ssn6 and the homeodomain of α2
    • 1:CAS:528:DC%2BD3cXislSgsbY%3D 10.1073/pnas.070506797 10759558
    • RL Smith AD Johnson 2000 A sequence resembling a peroxisomal targeting sequence directs the interaction between the tetratricopeptide repeats of Ssn6 and the homeodomain of α2 Proc Natl Acad Sci USA 97 3901 3906 1:CAS:528:DC%2BD3cXislSgsbY%3D 10.1073/pnas.070506797 10759558
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3901-3906
    • Smith, R.L.1    Johnson, A.D.2
  • 44
    • 0028843868 scopus 로고
    • The tetratricopeptide repeats of Ssn6 interact with the homeo domain of α2
    • 1:CAS:528:DyaK2MXpvFWrt74%3D 10.1101/gad.9.23.2903 7498787
    • RL Smith MJ Redd AD Johnson 1995 The tetratricopeptide repeats of Ssn6 interact with the homeo domain of α2 Genes Dev 9 2903 2910 1:CAS:528:DyaK2MXpvFWrt74%3D 10.1101/gad.9.23.2903 7498787
    • (1995) Genes Dev , vol.9 , pp. 2903-2910
    • Smith, R.L.1    Redd, M.J.2    Johnson, A.D.3
  • 45
    • 0033133919 scopus 로고    scopus 로고
    • The WD repeat: A common architecture for diverse functions
    • 1:CAS:528:DyaK1MXkslSnsbc%3D 10.1016/S0968-0004(99)01384-5 10322433
    • TF Smith C Gaitatzes K Saxena EJ Neer 1999 The WD repeat: a common architecture for diverse functions Trends Biochem Sci 24 181 185 1:CAS:528:DyaK1MXkslSnsbc%3D 10.1016/S0968-0004(99)01384-5 10322433
    • (1999) Trends Biochem Sci , vol.24 , pp. 181-185
    • Smith, T.F.1    Gaitatzes, C.2    Saxena, K.3    Neer, E.J.4
  • 47
    • 0029557246 scopus 로고
    • UME6 is a central component of a developmental regulatory switch controlling meiosis-specific gene expression
    • 1:CAS:528:DyaK28Xhtl2rtg%3D%3D 10.1073/pnas.92.26.12490 8618927
    • CM Steber RE Esposito 1995 UME6 is a central component of a developmental regulatory switch controlling meiosis-specific gene expression Proc Natl Acad Sci USA 92 12490 12494 1:CAS:528:DyaK28Xhtl2rtg%3D%3D 10.1073/pnas.92.26.12490 8618927
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12490-12494
    • Steber, C.M.1    Esposito, R.E.2
  • 48
    • 0023666071 scopus 로고
    • Activation of the yeast HO gene by release from multiple negative controls
    • 1:CAS:528:DyaL1cXltVCjsA%3D%3D 10.1016/0092-8674(87)90235-2 3545494
    • PW Sternberg MJ Stern I Clark I Herskowitz 1987 Activation of the yeast HO gene by release from multiple negative controls Cell 48 567 577 1:CAS:528:DyaL1cXltVCjsA%3D%3D 10.1016/0092-8674(87)90235-2 3545494
    • (1987) Cell , vol.48 , pp. 567-577
    • Sternberg, P.W.1    Stern, M.J.2    Clark, I.3    Herskowitz, I.4
  • 49
    • 0024834986 scopus 로고
    • Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast
    • 1:CAS:528:DyaK3cXntFChsg%3D%3D 10.1073/pnas.86.24.10018 2690066
    • R Strich MR Slater RE Esposito 1989 Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast Proc Natl Acad Sci USA 86 10018 10022 1:CAS:528:DyaK3cXntFChsg%3D%3D 10.1073/pnas.86.24.10018 2690066
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 10018-10022
    • Strich, R.1    Slater, M.R.2    Esposito, R.E.3
  • 50
    • 70350761680 scopus 로고    scopus 로고
    • The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters
    • 1:CAS:528:DC%2BD1MXhtFWhu7zM 10.1038/emboj.2009.270 19745812
    • S Takahata Y Yu DJ Stillman 2009 The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters EMBO J 28 3378 3389 1:CAS:528:DC%2BD1MXhtFWhu7zM 10.1038/emboj.2009.270 19745812
    • (2009) EMBO J , vol.28 , pp. 3378-3389
    • Takahata, S.1    Yu, Y.2    Stillman, D.J.3
  • 51
    • 0028969881 scopus 로고
    • Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters
    • 1:CAS:528:DyaK2MXltVahtL0%3D 10.1101/gad.9.7.821 7705659
    • D Tzamarias K Struhl 1995 Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters Genes Dev 9 821 831 1:CAS:528:DyaK2MXltVahtL0%3D 10.1101/gad.9.7.821 7705659
    • (1995) Genes Dev , vol.9 , pp. 821-831
    • Tzamarias, D.1    Struhl, K.2
  • 52
    • 0030465738 scopus 로고    scopus 로고
    • Evidence that the transcriptional regulators SIN3 and RPD3, and a novel gene (SDS3) with similar functions, are involved in transcriptional silencing in S. cerevisiae
    • 1:CAS:528:DyaK2sXkslyitg%3D%3D 8978024
    • D Vannier D Balderes D Shore 1996 Evidence that the transcriptional regulators SIN3 and RPD3, and a novel gene (SDS3) with similar functions, are involved in transcriptional silencing in S. cerevisiae Genetics 144 1343 1353 1:CAS:528:DyaK2sXkslyitg%3D%3D 8978024
    • (1996) Genetics , vol.144 , pp. 1343-1353
    • Vannier, D.1    Balderes, D.2    Shore, D.3
  • 53
    • 0026046959 scopus 로고
    • RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes
    • 1:CAS:528:DyaK38Xhs1Kgug%3D%3D 1944290
    • M Vidal R Strich RE Esposito RF Gaber 1991 RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes Mol Cell Biol 11 6306 6316 1:CAS:528:DyaK38Xhs1Kgug%3D%3D 1944290
    • (1991) Mol Cell Biol , vol.11 , pp. 6306-6316
    • Vidal, M.1    Strich, R.2    Esposito, R.E.3    Gaber, R.F.4
  • 54
    • 0032812984 scopus 로고    scopus 로고
    • Overproduction of the Opi1 repressor inhibits transcriptional activation of structural genes required for phospholipid biosynthesis in the yeast Saccharomyces cerevisiae
    • 1:CAS:528:DyaK1MXkvVOjt78%3D 10.1002/(SICI)1097-0061(199907)15: 10A<843::AID-YEA424>3.0.CO;2-M 10407264
    • C Wagner M Blank B Strohmann HJ Schüller 1999 Overproduction of the Opi1 repressor inhibits transcriptional activation of structural genes required for phospholipid biosynthesis in the yeast Saccharomyces cerevisiae Yeast 15 843 854 1:CAS:528:DyaK1MXkvVOjt78%3D 10.1002/(SICI)1097-0061(199907)15:10A<843:: AID-YEA424>3.0.CO;2-M 10407264
    • (1999) Yeast , vol.15 , pp. 843-854
    • Wagner, C.1    Blank, M.2    Strohmann, B.3    Schüller, H.J.4
  • 55
    • 0034936617 scopus 로고    scopus 로고
    • The negative regulator Opi1 of phospholipid biosynthesis in yeast contacts the pleiotropic repressor Sin3 and the transcriptional activator Ino2
    • 1:CAS:528:DC%2BD3MXlsVGhsrc%3D 10.1046/j.1365-2958.2001.02495.x 11454208
    • C Wagner M Dietz J Wittmann A Albrecht HJ Schüller 2001 The negative regulator Opi1 of phospholipid biosynthesis in yeast contacts the pleiotropic repressor Sin3 and the transcriptional activator Ino2 Mol Microbiol 41 155 166 1:CAS:528:DC%2BD3MXlsVGhsrc%3D 10.1046/j.1365-2958.2001.02495.x 11454208
    • (2001) Mol Microbiol , vol.41 , pp. 155-166
    • Wagner, C.1    Dietz, M.2    Wittmann, J.3    Albrecht, A.4    Schüller, H.J.5
  • 56
    • 0027479075 scopus 로고
    • Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein
    • 1:CAS:528:DyaK3sXhvVGjt70%3D 8441414
    • H Wang DJ Stillman 1993 Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein Mol Cell Biol 13 1805 1814 1:CAS:528:DyaK3sXhvVGjt70%3D 8441414
    • (1993) Mol Cell Biol , vol.13 , pp. 1805-1814
    • Wang, H.1    Stillman, D.J.2
  • 57
    • 0025096058 scopus 로고
    • The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs
    • 1:CAS:528:DyaK3MXhsFyisbw%3D 2233725
    • H Wang I Clark PR Nicholson I Herskowitz DJ Stillman 1990 The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs Mol Cell Biol 10 5927 5936 1:CAS:528: DyaK3MXhsFyisbw%3D 2233725
    • (1990) Mol Cell Biol , vol.10 , pp. 5927-5936
    • Wang, H.1    Clark, I.2    Nicholson, P.R.3    Herskowitz, I.4    Stillman, D.J.5
  • 58
    • 0034996711 scopus 로고    scopus 로고
    • Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast
    • 1:CAS:528:DC%2BD3MXjslWhtLw%3D 10.1128/MCB.21.6.2057-2069.2001 11238941
    • BK Washburn RE Esposito 2001 Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast Mol Cell Biol 21 2057 2069 1:CAS:528:DC%2BD3MXjslWhtLw%3D 10.1128/MCB.21.6.2057-2069.2001 11238941
    • (2001) Mol Cell Biol , vol.21 , pp. 2057-2069
    • Washburn, B.K.1    Esposito, R.E.2
  • 59
    • 0034312312 scopus 로고    scopus 로고
    • Ssn6-Tup1 interacts with class i histone deacetylases required for repression
    • 1:CAS:528:DC%2BD3cXotFOju7g%3D 10.1101/gad.829100 11069890
    • AD Watson DG Edmondson JR Bone Y Mukai Y Yu W Du DJ Stillman SY Roth 2000 Ssn6-Tup1 interacts with class I histone deacetylases required for repression Genes Dev 14 2737 2744 1:CAS:528:DC%2BD3cXotFOju7g%3D 10.1101/gad.829100 11069890
    • (2000) Genes Dev , vol.14 , pp. 2737-2744
    • Watson, A.D.1    Edmondson, D.G.2    Bone, J.R.3    Mukai, Y.4    Yu, Y.5    Du, W.6    Stillman, D.J.7    Roth, S.Y.8
  • 60
    • 57649223684 scopus 로고    scopus 로고
    • Amino acids induce peptide uptake via accelerated degradation of CUP9, the transcriptional repressor of the PTR2 peptide transporter
    • 1:CAS:528:DC%2BD1cXht1Glsb7K 10.1074/jbc.M803980200 18708352
    • Z Xia GC Turner CS Hwang C Byrd A Varshavsky 2008 Amino acids induce peptide uptake via accelerated degradation of CUP9, the transcriptional repressor of the PTR2 peptide transporter J Biol Chem 283 28958 28968 1:CAS:528:DC%2BD1cXht1Glsb7K 10.1074/jbc.M803980200 18708352
    • (2008) J Biol Chem , vol.283 , pp. 28958-28968
    • Xia, Z.1    Turner, G.C.2    Hwang, C.S.3    Byrd, C.4    Varshavsky, A.5
  • 61
    • 0026685177 scopus 로고
    • The Saccharomyces cerevisiae GAM2/SIN3 protein plays a role in both activation and repression of transcription
    • 1:CAS:528:DyaK38Xks1Chs7w%3D 10.1007/BF00587597 1603074
    • H Yoshimoto M Ohmae I Yamashita 1992 The Saccharomyces cerevisiae GAM2/SIN3 protein plays a role in both activation and repression of transcription Mol Gen Genet 233 327 330 1:CAS:528:DyaK38Xks1Chs7w%3D 10.1007/BF00587597 1603074
    • (1992) Mol Gen Genet , vol.233 , pp. 327-330
    • Yoshimoto, H.1    Ohmae, M.2    Yamashita, I.3
  • 62
    • 0028211739 scopus 로고
    • Evidence that TUP1/SSN6 has a positive effect on the activity of the yeast activator HAP1
    • 1:STN:280:DyaK2c3nsVSgsQ%3D%3D 8005436
    • L Zhang L Guarente 1994 Evidence that TUP1/SSN6 has a positive effect on the activity of the yeast activator HAP1 Genetics 136 813 817 1:STN:280:DyaK2c3nsVSgsQ%3D%3D 8005436
    • (1994) Genetics , vol.136 , pp. 813-817
    • Zhang, L.1    Guarente, L.2


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