-
1
-
-
0029789066
-
-
R. Haubner, W. Schmitt, G. Hölzemann, S. L. Goodman, A. Jonczyk, H. Kessler, J. Am. Chem. Soc. 1996, 118, 7881-7891;
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 7881-7891
-
-
Haubner, R.1
Schmitt, W.2
Hölzemann, G.3
Goodman, S.L.4
Jonczyk, A.5
Kessler, H.6
-
2
-
-
1542353892
-
-
L. Belvisi, A. Bernardi, A. Checchia, L. Manzoni, D. Potenza, C. Scolastico, M. Castorina, A. Cupelli, G. Giannini, P. Carminati, C. Pisano, Org. Lett. 2001, 3, 1001-1004;
-
(2001)
Org. Lett.
, vol.3
, pp. 1001-1004
-
-
Belvisi, L.1
Bernardi, A.2
Checchia, A.3
Manzoni, L.4
Potenza, D.5
Scolastico, C.6
Castorina, M.7
Cupelli, A.8
Giannini, G.9
Carminati, P.10
Pisano, C.11
-
3
-
-
34250770070
-
-
S. Urman, K. Gaus, Y. Yang, U. Strijowski, N. Sewald, S. De Pol, O. Reiser, Angew. Chem. 2007, 119, 4050-4053; Angew. Chem. Int. Ed. 2007, 46, 3976-3978;
-
(2007)
Angew. Chem. 2007, 119, 4050-4053; Angew. Chem. Int. Ed.
, vol.46
, pp. 3976-3978
-
-
Urman, S.1
Gaus, K.2
Yang, Y.3
Strijowski, U.4
Sewald, N.5
De Pol, S.6
Reiser, O.7
-
4
-
-
70849100631
-
-
A. S. M. da Ressurreicao, A. Vidu, M. Civera, L. Belvisi, D. Potenza, L. Manzoni, S. Ongeri, C. Gennari, U. Piarulli, Chem. Eur. J. 2009, 15, 12184-12188.
-
(2009)
Chem. Eur. J.
, vol.15
, pp. 12184-12188
-
-
da Ressurreicao, A.S.M.1
Vidu, A.2
Civera, M.3
Belvisi, L.4
Potenza, D.5
Manzoni, L.6
Ongeri, S.7
Gennari, C.8
Piarulli, U.9
-
5
-
-
0037023363
-
-
J.-P. Xiong, T. Stehle, R. Zhang, A. Joachimiak, M. Frech, S. L. Goodman, M. A. Arnaout, Science 2002, 296, 151-155;
-
(2002)
Science
, vol.296
, pp. 151-155
-
-
Xiong, J.-P.1
Stehle, T.2
Zhang, R.3
Joachimiak, A.4
Frech, M.5
Goodman, S.L.6
Arnaout, M.A.7
-
6
-
-
0141958105
-
-
L. Marinelli, A. Lavechia, K. E. Gottschalk, E. Novellino, H. Kessler, J. Med. Chem. 2003, 46, 4393-4404;
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4393-4404
-
-
Marinelli, L.1
Lavechia, A.2
Gottschalk, K.E.3
Novellino, E.4
Kessler, H.5
-
7
-
-
7944225864
-
-
D. Craig, M. Gao, K. Schulten, V. Vogel, Structure 2004, 12, 2049-2058;
-
(2004)
Structure
, vol.12
, pp. 2049-2058
-
-
Craig, D.1
Gao, M.2
Schulten, K.3
Vogel, V.4
-
8
-
-
77950473237
-
-
T. Cupido, J. Spengler, J. Ruiz-Rodriguez, J. Adan, F. Mitjans, J. Piulats, F. Albericio, Angew. Chem. 2010, 122, 2792-2797; Angew. Chem. Int. Ed. 2010, 49, 2732-2737.
-
(2010)
Angew. Chem. 2010, 122, 2792-2797; Angew. Chem. Int. Ed.
, vol.49
, pp. 2732-2737
-
-
Cupido, T.1
Spengler, J.2
Ruiz-Rodriguez, J.3
Adan, J.4
Mitjans, F.5
Piulats, J.6
Albericio, F.7
-
9
-
-
61449220945
-
-
For a genetic and cell biological analysis of integrin outside-in signaling see,.
-
For a genetic and cell biological analysis of integrin outside-in signaling see: K. R. Legate, S. A. Wickström, R. Fässler, Genes Dev. 2009, 23, 397-418.
-
(2009)
Genes Dev.
, vol.23
, pp. 397-418
-
-
Legate, K.R.1
Wickström, S.A.2
Fässler, R.3
-
10
-
-
70449635893
-
-
For a recent review on the resistance to anti-angiogenic therapies, see,.
-
For a recent review on the resistance to anti-angiogenic therapies, see: Y. Crawford, N. Ferrara, Trends Pharmacol. Sci. 2009, 30, 624-630.
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 624-630
-
-
Crawford, Y.1
Ferrara, N.2
-
12
-
-
70349782389
-
-
S. P. Ivy, J. Y. Wick, B. M. Kaufman, Nat. Rev. Clin. Oncol. 2009, 6, 569-579.
-
(2009)
Nat. Rev. Clin. Oncol.
, vol.6
, pp. 569-579
-
-
Ivy, S.P.1
Wick, J.Y.2
Kaufman, B.M.3
-
13
-
-
70349686898
-
-
C. Clapp, S. Thebault, M. C. Jeziorski, G. Martinez De La Escalera, Physiol. Rev. 2009, 89, 1177-1215.
-
(2009)
Physiol. Rev.
, vol.89
, pp. 1177-1215
-
-
Clapp, C.1
Thebault, S.2
Jeziorski, M.C.3
Martinez De La Escalera, G.4
-
14
-
-
14044262886
-
Houben-Weyl Methods of Organic Chemistry, Vol. E22b: Synthesis of Peptides and Peptidomimetics
-
in (Eds.: M. Goodman, A. Felix, L. Moroder, C. Toniolo) Thieme, Stuttgart.
-
C. Gilon, C. Mang, E. Lohof, A. Friedler, H. Kessler in Houben-Weyl Methods of Organic Chemistry, Vol. E22b: Synthesis of Peptides and Peptidomimetics (Eds.: M. Goodman, A. Felix, L. Moroder, C. Toniolo) Thieme, Stuttgart, 2003, pp. 461-542;
-
(2003)
, pp. 461-542
-
-
Gilon, C.1
Mang, C.2
Lohof, E.3
Friedler, A.4
Kessler, H.5
-
15
-
-
0027102818
-
-
M. Gurrath, G. Müller, H. Kessler, M. Aumailley, R. Timpl, Eur. J. Biochem. 1992, 210, 911-921.
-
(1992)
Eur. J. Biochem.
, vol.210
, pp. 911-921
-
-
Gurrath, M.1
Müller, G.2
Kessler, H.3
Aumailley, M.4
Timpl, R.5
-
16
-
-
0019163001
-
-
R. M. Freidinger, D. F. Veber, D. S. Perlow, J. R. Brooks, R. Saperstein, Science 1980, 210, 656;
-
(1980)
Science
, vol.210
, pp. 656
-
-
Freidinger, R.M.1
Veber, D.F.2
Perlow, D.S.3
Brooks, J.R.4
Saperstein, R.5
-
18
-
-
0034640054
-
-
G. V. Nikiforovich, K. E. Kövér, W.-J. Zhang, G. R. Marshall, J. Am. Chem. Soc. 2000, 122, 3262-3273.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 3262-3273
-
-
Nikiforovich, G.V.1
Kövér, K.E.2
Zhang, W.-J.3
Marshall, G.R.4
-
19
-
-
0033549864
-
-
M. A. Dechantsreiter, E. Planker, B. Mathä, E. Lohof, G. Hölzemann, A. Jonczyk, S. L. Goodman, H. Kessler, J. Med. Chem. 1999, 42, 3033-3040.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 3033-3040
-
-
Dechantsreiter, M.A.1
Planker, E.2
Mathä, B.3
Lohof, E.4
Hölzemann, G.5
Jonczyk, A.6
Goodman, S.L.7
Kessler, H.8
-
20
-
-
9144267831
-
-
C. Palomo, J. M. Aizpurua, A. Benito, J. I. Miranda, R. M. Fratila, C. Matute, M. Domercq, F. Gago, S. Martin-Santamaria, A. Linden, J. Am. Chem. Soc. 2003, 125, 16243-16260.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 16243-16260
-
-
Palomo, C.1
Aizpurua, J.M.2
Benito, A.3
Miranda, J.I.4
Fratila, R.M.5
Matute, C.6
Domercq, M.7
Gago, F.8
Martin-Santamaria, S.9
Linden, A.10
-
21
-
-
79551539562
-
-
C. Palomo, J. M. Aizpurua, E. Balentova, A. Jimenez, J. Oyarbide, R. M. Fratila, J. I. Miranda, Org. Lett. 2008, 10, 101-104.
-
(2008)
Org. Lett.
, vol.10
, pp. 101-104
-
-
Palomo, C.1
Aizpurua, J.M.2
Balentova, E.3
Jimenez, A.4
Oyarbide, J.5
Fratila, R.M.6
Miranda, J.I.7
-
22
-
-
66749190071
-
-
J. M. Beierle, W. S. Horne, J. H. van Maarseveen, B. Waser, J. C. Reubi, M. R. Ghadiri, Angew. Chem. 2009, 121, 4819-4823; Angew. Chem. Int. Ed. 2009, 48, 4725-4729.
-
(2009)
Angew. Chem. 2009, 121, 4819-4823; Angew. Chem. Int. Ed.
, vol.48
, pp. 4725-4729
-
-
Beierle, J.M.1
Horne, W.S.2
van Maarseveen, J.H.3
Waser, B.4
Reubi, J.C.5
Ghadiri, M.R.6
-
23
-
-
19844372066
-
-
For a review on conformation-directed macrocyclizations, see,.
-
For a review on conformation-directed macrocyclizations, see: J. Blankenstein, J. Zhu, Eur. J. Org. Chem. 2005, 1949-1964.
-
(2005)
Eur. J. Org. Chem.
, pp. 1949-1964
-
-
Blankenstein, J.1
Zhu, J.2
-
24
-
-
0035798080
-
-
M. Kawaguchi, R. Hosotani, S. Ohishi, N. Fujii, S. S. Tulachan, M. Koizumi, E. Toyoda, T. Masui, S. Nakajima, S. Tsuji, J. Ida, K. Fujimoto, M. Wada, R. Doi, M. Imamura, Biochem. Biophys. Res. Commun. 2001, 288, 711-717.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.288
, pp. 711-717
-
-
Kawaguchi, M.1
Hosotani, R.2
Ohishi, S.3
Fujii, N.4
Tulachan, S.S.5
Koizumi, M.6
Toyoda, E.7
Masui, T.8
Nakajima, S.9
Tsuji, S.10
Ida, J.11
Fujimoto, K.12
Wada, M.13
Doi, R.14
Imamura, M.15
-
25
-
-
0030768536
-
-
R. Haubner, D. Finsinger, H. Kessler, Angew. Chem. 1997, 109, 1440-1456; Angew. Chem. Int. Ed. Engl. 1997, 36, 1374-1389.
-
(1997)
Angew. Chem. 1997, 109, 1440-1456; Angew. Chem. Int. Ed. Engl.
, vol.36
, pp. 1374-1389
-
-
Haubner, R.1
Finsinger, D.2
Kessler, H.3
-
26
-
-
79551539046
-
-
Three additional diastereomers of compound 4a were prepared, their conformations in water were studied, and their binding abilities were tested: see pages S20-S21 in the Supporting Information.
-
Three additional diastereomers of compound 4a were prepared, their conformations in water were studied, and their binding abilities were tested: see pages S20-S21 in the Supporting Information.
-
-
-
-
27
-
-
4444279818
-
-
S. Kostidis, A. Stavrakoudis, N. Biris, D. Tsoukatos, C. Sakarellos, V. Tsikaris, J. Pept. Sci. 2004, 10, 494-509;
-
(2004)
J. Pept. Sci.
, vol.10
, pp. 494-509
-
-
Kostidis, S.1
Stavrakoudis, A.2
Biris, N.3
Tsoukatos, D.4
Sakarellos, C.5
Tsikaris, V.6
-
28
-
-
42149155659
-
-
See also ref. [2d].
-
M. Salvati, F. M. Cordero, F. Pisaneschi, F. Melani, P. Gratteri, N. Cini, A. Bottoncetti, A. Brandi, Bioorg. Med. Chem. 2008, 16, 4262-4271. See also ref. [2d].
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 4262-4271
-
-
Salvati, M.1
Cordero, F.M.2
Pisaneschi, F.3
Melani, F.4
Gratteri, P.5
Cini, N.6
Bottoncetti, A.7
Brandi, A.8
-
30
-
-
64149106522
-
-
For an example of pro-angiogenic behavior of RGD-mimetic integrin inhibitors.
-
For an example of pro-angiogenic behavior of RGD-mimetic integrin inhibitors, see: A. R. Reynolds, I. R. Hart, A. R. Watson, J. C. Weiti, R. G. Silva, S. D. Robinson, G. Da Violante, M. Gourlaouen, M. Salih, M. C. Jones, D. T. Jones, G. Saunders, V. Kostourou, F. Perron-Sierra, J. C. Norman, G. C. Tucker, K. M. Hodivala-Dilke, Nat. Med. 2009, 15, 392-400.
-
(2009)
Nat. Med.
, vol.15
, pp. 392-400
-
-
Reynolds, A.R.1
Hart, I.R.2
Watson, A.R.3
Weiti, J.C.4
Silva, R.G.5
Robinson, S.D.6
Da Violante, G.7
Gourlaouen, M.8
Salih, M.9
Jones, M.C.10
Jones, D.T.11
Saunders, G.12
Kostourou, V.13
Perron-Sierra, F.14
Norman, J.C.15
Tucker, G.C.16
Hodivala-Dilke, K.M.17
-
31
-
-
34548384400
-
-
M. Tomomura, N. Morita, F. Yoshikawa, A. Konishi, H. Akiyama, T. Furuichi, H. Kamiguchi, Neuroscience 2007, 148, 510-521.
-
(2007)
Neuroscience
, vol.148
, pp. 510-521
-
-
Tomomura, M.1
Morita, N.2
Yoshikawa, F.3
Konishi, A.4
Akiyama, H.5
Furuichi, T.6
Kamiguchi, H.7
-
32
-
-
77956523665
-
-
J. Ding, Z. Zhang, G. J. Roberts, M. Falcone, Y. Miao, Y. Shao, X. C. Zhang, D. W. Andrews, J. Lin, J. Biol. Chem. 2010, 285, 28749-28763.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 28749-28763
-
-
Ding, J.1
Zhang, Z.2
Roberts, G.J.3
Falcone, M.4
Miao, Y.5
Shao, Y.6
Zhang, X.C.7
Andrews, D.W.8
Lin, J.9
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