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Volumn 31, Issue 3, 2011, Pages 303-312

Effect of mutant β-catenin on liver growth homeostasis and hepatocarcinogenesis in transgenic mice

Author keywords

Catenin; Hepatocyte transplantation; Liver cancer; Transgenic mice

Indexed keywords

AMMONIA; BETA CATENIN;

EID: 79551528731     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2010.02430.x     Document Type: Article
Times cited : (6)

References (32)
  • 1
    • 0035936026 scopus 로고    scopus 로고
    • Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors
    • Aydinlik H, Nguyen TD, Moennikes O, Buchmann A, Schwarz M. Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors. Oncogene 2001; 20: 7812-6.
    • (2001) Oncogene , vol.20 , pp. 7812-7816
    • Aydinlik, H.1    Nguyen, T.D.2    Moennikes, O.3    Buchmann, A.4    Schwarz, M.5
  • 3
    • 0345006147 scopus 로고    scopus 로고
    • Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
    • De La Coste A, Romagnolo B, Billuart P, et al. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci USA 1998; 95: 8847-51.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8847-8851
    • De La Coste, A.1    Romagnolo, B.2    Billuart, P.3
  • 4
    • 0033584421 scopus 로고    scopus 로고
    • Mutation of beta-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis
    • Devereux TR, Anna CH, Foley JF, et al. Mutation of beta-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis. Oncogene 1999; 18: 4726-33.
    • (1999) Oncogene , vol.18 , pp. 4726-4733
    • Devereux, T.R.1    Anna, C.H.2    Foley, J.F.3
  • 5
    • 0034495080 scopus 로고    scopus 로고
    • Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis
    • Hsu HC, Jeng YM, Mao TL, et al. Beta-catenin mutations are associated with a subset of low-stage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis. Am J Pathol 2000; 157: 763-70.
    • (2000) Am J Pathol , vol.157 , pp. 763-770
    • Hsu, H.C.1    Jeng, Y.M.2    Mao, T.L.3
  • 6
    • 0032761853 scopus 로고    scopus 로고
    • Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection
    • Huang H, Fujii H, Sankila A, et al. Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection. Am J Pathol 1999; 155: 1795-801.
    • (1999) Am J Pathol , vol.155 , pp. 1795-1801
    • Huang, H.1    Fujii, H.2    Sankila, A.3
  • 7
    • 0032525836 scopus 로고    scopus 로고
    • Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3
    • Miyoshi Y, Iwao K, Nagasawa Y, et al. Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res 1998; 58: 2524-7.
    • (1998) Cancer Res , vol.58 , pp. 2524-2527
    • Miyoshi, Y.1    Iwao, K.2    Nagasawa, Y.3
  • 8
    • 0032885751 scopus 로고    scopus 로고
    • Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation
    • Nhieu JT, Renard CA, Wei Y, et al. Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation. Am J Pathol 1999; 155: 703-10.
    • (1999) Am J Pathol , vol.155 , pp. 703-710
    • Nhieu, J.T.1    Renard, C.A.2    Wei, Y.3
  • 9
    • 0037130449 scopus 로고    scopus 로고
    • Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
    • Taniguchi K, Roberts LR, Aderca IN, et al. Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 2002; 21: 4863-71.
    • (2002) Oncogene , vol.21 , pp. 4863-4871
    • Taniguchi, K.1    Roberts, L.R.2    Aderca, I.N.3
  • 10
    • 34248674146 scopus 로고    scopus 로고
    • WNT/beta-catenin signaling in liver health and disease
    • Thompson MD, Monga SP. WNT/beta-catenin signaling in liver health and disease. Hepatology 2007; 45: 1298-305.
    • (2007) Hepatology , vol.45 , pp. 1298-1305
    • Thompson, M.D.1    Monga, S.P.2
  • 11
    • 0035870293 scopus 로고    scopus 로고
    • Hepatomegaly in transgenic mice expressing an oncogenic form of beta-catenin
    • Cadoret A, Ovejero C, Saadi-Kheddouci S, et al. Hepatomegaly in transgenic mice expressing an oncogenic form of beta-catenin. Cancer Res 2001; 61: 3245-9.
    • (2001) Cancer Res , vol.61 , pp. 3245-3249
    • Cadoret, A.1    Ovejero, C.2    Saadi-Kheddouci, S.3
  • 12
    • 0036531817 scopus 로고    scopus 로고
    • Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin
    • Harada N, Miyoshi H, Murai N, et al. Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin. Cancer Res 2002; 62: 1971-7.
    • (2002) Cancer Res , vol.62 , pp. 1971-1977
    • Harada, N.1    Miyoshi, H.2    Murai, N.3
  • 13
    • 1642535593 scopus 로고    scopus 로고
    • Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations
    • Harada N, Oshima H, Katoh M, et al. Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations. Cancer Res 2004; 64: 48-54.
    • (2004) Cancer Res , vol.64 , pp. 48-54
    • Harada, N.1    Oshima, H.2    Katoh, M.3
  • 14
    • 71049143563 scopus 로고    scopus 로고
    • Hepatocellular carcinoma development induced by conditional beta-catenin activation in Lkb1+/- mice
    • Miyoshi H, Deguchi A, Nakau M, et al. Hepatocellular carcinoma development induced by conditional beta-catenin activation in Lkb1+/- mice. Cancer Sci 2009; 100: 2046-53.
    • (2009) Cancer Sci , vol.100 , pp. 2046-2053
    • Miyoshi, H.1    Deguchi, A.2    Nakau, M.3
  • 15
    • 77951487860 scopus 로고    scopus 로고
    • Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin
    • Nejak-Bowen KN, Thompson MD, Singh S, et al. Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin. Hepatology 2009; 51: 1603-13.
    • (2009) Hepatology , vol.51 , pp. 1603-1613
    • Nejak-Bowen, K.N.1    Thompson, M.D.2    Singh, S.3
  • 16
    • 10344254872 scopus 로고    scopus 로고
    • Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
    • Colnot S, Decaens T, Niwa-Kawakita M, et al. Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas. Proc Natl Acad Sci USA 2004; 101: 17216-21.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 17216-17221
    • Colnot, S.1    Decaens, T.2    Niwa-Kawakita, M.3
  • 17
    • 33744495398 scopus 로고    scopus 로고
    • Apc tumor suppressor gene is the "zonation-keeper" of mouse liver
    • Benhamouche S, Decaens T, Godard C, et al. Apc tumor suppressor gene is the "zonation-keeper" of mouse liver. Dev Cell 2006; 10: 759-70.
    • (2006) Dev Cell , vol.10 , pp. 759-770
    • Benhamouche, S.1    Decaens, T.2    Godard, C.3
  • 21
    • 0033636738 scopus 로고    scopus 로고
    • Hepatocyte transplantation into diseased mouse liver. Kinetics of parenchymal repopulation and identification of the proliferative capacity of tetraploid and octaploid hepatocytes
    • Weglarz TC, Degen JL, Sandgren EP. Hepatocyte transplantation into diseased mouse liver. Kinetics of parenchymal repopulation and identification of the proliferative capacity of tetraploid and octaploid hepatocytes. Am J Pathol 2000; 157: 1963-74.
    • (2000) Am J Pathol , vol.157 , pp. 1963-1974
    • Weglarz, T.C.1    Degen, J.L.2    Sandgren, E.P.3
  • 22
    • 0029763587 scopus 로고    scopus 로고
    • Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice
    • Kistner A, Gossen M, Zimmermann F, et al. Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci USA 1996; 93: 10933-8.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10933-10938
    • Kistner, A.1    Gossen, M.2    Zimmermann, F.3
  • 23
    • 1642580618 scopus 로고    scopus 로고
    • Mammary gland development requires syndecan-1 to create a beta-catenin/TCF-responsive mammary epithelial subpopulation
    • Liu BY, Kim YC, Leatherberry V, Cowin P, Alexander CM. Mammary gland development requires syndecan-1 to create a beta-catenin/TCF-responsive mammary epithelial subpopulation. Oncogene 2003; 22: 9243-53.
    • (2003) Oncogene , vol.22 , pp. 9243-9253
    • Liu, B.Y.1    Kim, Y.C.2    Leatherberry, V.3    Cowin, P.4    Alexander, C.M.5
  • 24
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen M, Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 1992; 89: 5547-51.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 25
    • 77955689062 scopus 로고    scopus 로고
    • Quantifying growth and transformation frequency of oncogene-expressing mouse hepatocytes in vivo
    • Figueiredo ML, Wentworth KM, Sandgren EP. Quantifying growth and transformation frequency of oncogene-expressing mouse hepatocytes in vivo. Hepatology 2010; 52: 634-43.
    • (2010) Hepatology , vol.52 , pp. 634-643
    • Figueiredo, M.L.1    Wentworth, K.M.2    Sandgren, E.P.3
  • 26
    • 0033902798 scopus 로고    scopus 로고
    • Cellular origin of regenerating parenchyma in a mouse model of severe hepatic injury
    • Braun KM, Sandgren EP. Cellular origin of regenerating parenchyma in a mouse model of severe hepatic injury. Am J Pathol 2000; 157: 561-9.
    • (2000) Am J Pathol , vol.157 , pp. 561-569
    • Braun, K.M.1    Sandgren, E.P.2
  • 28
    • 33847643776 scopus 로고    scopus 로고
    • Quantification of mRNA using real-time RT-PCR
    • Nolan T, Hands RE, Bustin SA. Quantification of mRNA using real-time RT-PCR. Nat Protoc 2006; 1: 1559-82.
    • (2006) Nat Protoc , vol.1 , pp. 1559-1582
    • Nolan, T.1    Hands, R.E.2    Bustin, S.A.3
  • 29
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034.
    • Vandesompele J, De Preter K, Pattyn F, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3: RESEARCH0034.1-12.
    • (2002) Genome Biol , vol.3 , pp. 1-12
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3
  • 30
    • 0003854151 scopus 로고
    • Exploratory Data Analysis
    • 2nd edn. Reading, MA: Addison-Wesley,
    • Tukey J. Exploratory Data Analysis, 2nd edn. Reading, MA: Addison-Wesley, 1977.
    • (1977)
    • Tukey, J.1
  • 31
    • 2142812377 scopus 로고    scopus 로고
    • Disruption of beta-catenin pathway or genomic instability define two distinct categories of liver cancer in transgenic mice
    • Calvisi DF, Factor VM, Ladu S, Conner EA, Thorgeirsson SS. Disruption of beta-catenin pathway or genomic instability define two distinct categories of liver cancer in transgenic mice. Gastroenterology 2004; 126: 1374-86.
    • (2004) Gastroenterology , vol.126 , pp. 1374-1386
    • Calvisi, D.F.1    Factor, V.M.2    Ladu, S.3    Conner, E.A.4    Thorgeirsson, S.S.5
  • 32
    • 23044438566 scopus 로고    scopus 로고
    • Genotype-phenotype relationships in hepatocellular tumors from mice and man
    • Stahl S, Ittrich C, Marx-Stoelting P, et al. Genotype-phenotype relationships in hepatocellular tumors from mice and man. Hepatology 2005; 42: 353-61.
    • (2005) Hepatology , vol.42 , pp. 353-361
    • Stahl, S.1    Ittrich, C.2    Marx-Stoelting, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.