Meiotic recombination favors the spreading of deleterious mutations in human populations

Human Mutation

Volumn 32, Issue 2, 2011, Pages 198-206

  Necşulea, Anamaria ^a   Popa, Alexandra ^a   Cooper, David N ^b   Stenson, Peter D ^b   Mouchiroud, Dominique ^a   Gautier, Christian ^a   Duret, Laurent ^a  

^a UNIVERSITÉ LYON 1   (France)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Derived allele frequencies; Disease associated mutations; Gene conversion; Meiotic recombination; Polymorphisms

Indexed keywords

ARTICLE; AT RICH SEQUENCE; GC RICH SEQUENCE; GENE CONVERSION; GENE FREQUENCY; GENE MUTATION; GENETIC RECOMBINATION; HUMAN; MEIOTIC RECOMBINATION; PRIORITY JOURNAL; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 79551513533     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21407     Document Type: Article

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