-
1
-
-
0035856920
-
Global and societal implications of the diabetes epidemic
-
Zimmet P, Alberti KG, Shaw J (2001) Global and societal implications of the diabetes epidemic. Nature 414: 782-787.
-
(2001)
Nature
, vol.414
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.2
Shaw, J.3
-
2
-
-
0033849777
-
Obesity and insulin resistance
-
Kahn BB, Flier JS (2000) Obesity and insulin resistance. J Clin Invest 106: 473-481.
-
(2000)
J Clin Invest
, vol.106
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
4
-
-
0035936764
-
Obesity and the regulation of energy balance
-
Spiegelman BM, Flier JS (2001) Obesity and the regulation of energy balance. Cell 104: 531-543.
-
(2001)
Cell
, vol.104
, pp. 531-543
-
-
Spiegelman, B.M.1
Flier, J.S.2
-
5
-
-
0028898298
-
Dietary fat and obesity: Evidence from epidemiology
-
Lissner L, Heitmann BL (1995) Dietary fat and obesity: evidence from epidemiology. Eur J Clin Nutr 49: 79-90.
-
(1995)
Eur J Clin Nutr
, vol.49
, pp. 79-90
-
-
Lissner, L.1
Heitmann, B.L.2
-
6
-
-
0031773187
-
Dietary fat intake does affect obesity!
-
Bray GA, Popkin BM (1998) Dietary fat intake does affect obesity! Am J Clin Nutr 68: 1157-1173.
-
(1998)
Am J Clin Nutr
, vol.68
, pp. 1157-1173
-
-
Bray, G.A.1
Popkin, B.M.2
-
8
-
-
34248393099
-
High-fat diets: Modeling the metabolic disorders of human obesity in rodents
-
Buettner R, Scholmerich J, Bollheimer LC (2007) High-fat diets: modeling the metabolic disorders of human obesity in rodents. Obesity (Silver Spring) 15: 798-808.
-
(2007)
Obesity (Silver Spring)
, vol.15
, pp. 798-808
-
-
Buettner, R.1
Scholmerich, J.2
Bollheimer, L.C.3
-
9
-
-
35248837988
-
Renaming the DSCR1/Adapt78 gene family as RCAN: Regulators of calcineurin
-
Davies KJ, Ermak G, Rothermel BA, Pritchard M, Heitman J, et al. (2007) Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. Faseb J 21: 3023-3028.
-
(2007)
Faseb J
, vol.21
, pp. 3023-3028
-
-
Davies, K.J.1
Ermak, G.2
Rothermel, B.A.3
Pritchard, M.4
Heitman, J.5
-
10
-
-
15844423313
-
Molecular cloning of a novel thyroid hormone-responsive gene, ZAKI-4, in human skin fibroblasts
-
Miyazaki T, Kanou Y, Murata Y, Ohmori S, Niwa T, et al. (1996) Molecular cloning of a novel thyroid hormone-responsive gene, ZAKI-4, in human skin fibroblasts. J Biol Chem 271: 14567-14571.
-
(1996)
J Biol Chem
, vol.271
, pp. 14567-14571
-
-
Miyazaki, T.1
Kanou, Y.2
Murata, Y.3
Ohmori, S.4
Niwa, T.5
-
11
-
-
0034234963
-
A conserved family of calcineurin regulators
-
Kingsbury TJ, Cunningham KW (2000) A conserved family of calcineurin regulators. Genes Dev 14: 1595-1604.
-
(2000)
Genes Dev
, vol.14
, pp. 1595-1604
-
-
Kingsbury, T.J.1
Cunningham, K.W.2
-
12
-
-
0037109035
-
Novel human ZAKI-4 isoforms: Hormonal and tissue-specific regulation and function as calcineurin inhibitors
-
Cao X, Kambe F, Miyazaki T, Sarkar D, Ohmori S, et al. (2002) Novel human ZAKI-4 isoforms: hormonal and tissue-specific regulation and function as calcineurin inhibitors. Biochem J 367: 459-466.
-
(2002)
Biochem J
, vol.367
, pp. 459-466
-
-
Cao, X.1
Kambe, F.2
Miyazaki, T.3
Sarkar, D.4
Ohmori, S.5
-
13
-
-
1842422379
-
Genomic organization of mouse ZAKI-4 gene that encodes ZAKI-4 alpha and beta isoforms, endogenous calcineurin inhibitors, and changes in the expression of these isoforms by thyroid hormone in adult mouse brain and heart
-
Mizuno Y, Kanou Y, Rogatcheva M, Imai T, Refetoff S, et al. (2004) Genomic organization of mouse ZAKI-4 gene that encodes ZAKI-4 alpha and beta isoforms, endogenous calcineurin inhibitors, and changes in the expression of these isoforms by thyroid hormone in adult mouse brain and heart. Eur J Endocrinol 150: 371-380.
-
(2004)
Eur J Endocrinol
, vol.150
, pp. 371-380
-
-
Mizuno, Y.1
Kanou, Y.2
Rogatcheva, M.3
Imai, T.4
Refetoff, S.5
-
14
-
-
33646565313
-
Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo
-
Sanna B, Brandt EB, Kaiser RA, Pfluger P, Witt SA, et al. (2006) Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo. Proc Natl Acad Sci U S A 103: 7327-7332.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 7327-7332
-
-
Sanna, B.1
Brandt, E.B.2
Kaiser, R.A.3
Pfluger, P.4
Witt, S.A.5
-
15
-
-
0032538890
-
Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase
-
Shima H, Pende M, Chen Y, Fumagalli S, Thomas G, et al. (1998) Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase. Embo J 17: 6649-6659.
-
(1998)
Embo J
, vol.17
, pp. 6649-6659
-
-
Shima, H.1
Pende, M.2
Chen, Y.3
Fumagalli, S.4
Thomas, G.5
-
16
-
-
4544220704
-
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
-
Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, et al. (2004) Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. Nature 431: 200-205.
-
(2004)
Nature
, vol.431
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
-
17
-
-
77449101244
-
A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes
-
Butler AA, Kozak LP (2010) A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes. Diabetes 59: 323-329.
-
(2010)
Diabetes
, vol.59
, pp. 323-329
-
-
Butler, A.A.1
Kozak, L.P.2
-
18
-
-
70450193472
-
Human genetics illuminates the paths to metabolic disease
-
O'Rahilly S (2009) Human genetics illuminates the paths to metabolic disease. Nature 462: 307-314.
-
(2009)
Nature
, vol.462
, pp. 307-314
-
-
O'Rahilly, S.1
-
19
-
-
18744427205
-
On raising energy expenditure in ob/ob mice
-
Himms-Hagen J (1997) On raising energy expenditure in ob/ob mice. Science 276: 1132-1133.
-
(1997)
Science
, vol.276
, pp. 1132-1133
-
-
Himms-Hagen, J.1
-
20
-
-
0842324779
-
Obesity wars: Molecular progress confronts an expanding epidemic
-
Flier JS (2004) Obesity wars: molecular progress confronts an expanding epidemic. Cell 116: 337-350.
-
(2004)
Cell
, vol.116
, pp. 337-350
-
-
Flier, J.S.1
-
21
-
-
12344277552
-
Diabetes, obesity, and the brain
-
Schwartz MW, Porte D, Jr. (2005) Diabetes, obesity, and the brain. Science 307: 375-379.
-
(2005)
Science
, vol.307
, pp. 375-379
-
-
Schwartz, M.W.1
Porte Jr., D.2
-
22
-
-
33748931457
-
Central nervous system control of food intake and body weight
-
Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW (2006) Central nervous system control of food intake and body weight. Nature 443: 289-295.
-
(2006)
Nature
, vol.443
, pp. 289-295
-
-
Morton, G.J.1
Cummings, D.E.2
Baskin, D.G.3
Barsh, G.S.4
Schwartz, M.W.5
-
23
-
-
0033082380
-
From lesions to leptin: Hypothalamic control of food intake and body weight
-
Elmquist JK, Elias CF, Saper CB (1999) From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22: 221-232.
-
(1999)
Neuron
, vol.22
, pp. 221-232
-
-
Elmquist, J.K.1
Elias, C.F.2
Saper, C.B.3
-
24
-
-
31944452253
-
The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight
-
King BM (2006) The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight. Physiol Behav 87: 221-244.
-
(2006)
Physiol Behav
, vol.87
, pp. 221-244
-
-
King, B.M.1
-
25
-
-
34548383138
-
Differential expression of members of the RCAN family of calcineurin regulators suggests selective functions for these proteins in the brain
-
Porta S, Marti E, de la Luna S, Arbones ML (2007) Differential expression of members of the RCAN family of calcineurin regulators suggests selective functions for these proteins in the brain. Eur J Neurosci 26: 1213-1226.
-
(2007)
Eur J Neurosci
, vol.26
, pp. 1213-1226
-
-
Porta, S.1
Marti, E.2
de la, L.S.3
Arbones, M.L.4
-
26
-
-
0023032057
-
The distribution of calcineurin in rat brain by light and electron microscopic immunohistochemistry and enzyme-immunoassay
-
Goto S, Matsukado Y, Mihara Y, Inoue N, Miyamoto E (1986) The distribution of calcineurin in rat brain by light and electron microscopic immunohistochemistry and enzyme-immunoassay. Brain Res 397: 161-172.
-
(1986)
Brain Res
, vol.397
, pp. 161-172
-
-
Goto, S.1
Matsukado, Y.2
Mihara, Y.3
Inoue, N.4
Miyamoto, E.5
-
27
-
-
0033200022
-
Comparative study of the distribution of calmodulin kinase II and calcineurin in the mouse brain
-
Sola C, Tusell JM, Serratosa J (1999) Comparative study of the distribution of calmodulin kinase II and calcineurin in the mouse brain. J Neurosci Res 57: 651-662.
-
(1999)
J Neurosci Res
, vol.57
, pp. 651-662
-
-
Sola, C.1
Tusell, J.M.2
Serratosa, J.3
-
28
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, et al. (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
-
29
-
-
13344295079
-
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
-
Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, et al. (1996) Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334: 292-295.
-
(1996)
N Engl J Med
, vol.334
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
Kriauciunas, A.4
Stephens, T.W.5
-
30
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, et al. (1995) Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1: 1155-1161.
-
(1995)
Nat Med
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
Pratley, R.E.4
Lee, G.H.5
-
31
-
-
13344279395
-
A role for melanin-concentrating hormone in the central regulation of feeding behaviour
-
Qu D, Ludwig DS, Gammeltoft S, Piper M, Pelleymounter MA, et al. (1996) A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature 380: 243-247.
-
(1996)
Nature
, vol.380
, pp. 243-247
-
-
Qu, D.1
Ludwig, D.S.2
Gammeltoft, S.3
Piper, M.4
Pelleymounter, M.A.5
-
32
-
-
0027319108
-
Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse
-
Wilding JP, Gilbey SG, Bailey CJ, Batt RA, Williams G, et al. (1993) Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse. Endocrinology 132: 1939-1944.
-
(1993)
Endocrinology
, vol.132
, pp. 1939-1944
-
-
Wilding, J.P.1
Gilbey, S.G.2
Bailey, C.J.3
Batt, R.A.4
Williams, G.5
-
33
-
-
11244346968
-
Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts
-
Cao X, Kambe F, Moeller LC, Refetoff S, Seo H (2005) Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts. Mol Endocrinol 19: 102-112.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 102-112
-
-
Cao, X.1
Kambe, F.2
Moeller, L.C.3
Refetoff, S.4
Seo, H.5
-
34
-
-
45549087105
-
The regulation of seasonal changes in food intake and body weight
-
Ebling FJ, Barrett P (2008) The regulation of seasonal changes in food intake and body weight. J Neuroendocrinol 20: 827-833.
-
(2008)
J Neuroendocrinol
, vol.20
, pp. 827-833
-
-
Ebling, F.J.1
Barrett, P.2
-
35
-
-
33746322135
-
What can we learn from seasonal animals about the regulation of energy balance?
-
Morgan PJ, Ross AW, Mercer JG, Barrett P (2006) What can we learn from seasonal animals about the regulation of energy balance? Prog Brain Res 153: 325-337.
-
(2006)
Prog Brain Res
, vol.153
, pp. 325-337
-
-
Morgan, P.J.1
Ross, A.W.2
Mercer, J.G.3
Barrett, P.4
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