Chapter 19: What can we learn from seasonal animals about the regulation of energy balance?

Progress in Brain Research

Volumn 153, Issue , 2006, Pages 325-337

  Morgan, Peter J ^a   Ross, Alexander W ^a   Mercer, Julian G ^a   Barrett, Perry ^a  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; HISTAMINE H3 RECEPTOR; LEPTIN; MELANOCORTIN 4 RECEPTOR; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR GAMMA; TRANSCRIPTION FACTOR;

ADAPTATION; ADIPOSE TISSUE; ANIMAL; ARCUATE NUCLEUS; BODY FAT; CIRCADIAN RHYTHM; CIRCANNUAL RHYTHM; CONTROL SYSTEM; DIET RESTRICTION; ENERGY BALANCE; ENERGY EXPENDITURE; ENVIRONMENTAL CHANGE; EXPERIMENTAL MOUSE; EXPERIMENTAL RAT; FEEDBACK SYSTEM; FOOD INTAKE; GENE EXPRESSION; GENE MUTATION; HAMSTER; HIBERNATION; METABOLIC REGULATION; NONHUMAN; OBESITY; PHODOPUS; PHOTOPERIODICITY; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; SEASONAL VARIATION; SIGNAL TRANSDUCTION; TIME; TISSUE DEGENERATION; WEIGHT CHANGE; WEIGHT REDUCTION; BODY WEIGHT; CYTOLOGY; ENERGY METABOLISM; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY; SEASON;

ANIMALS; ARCUATE NUCLEUS; BODY WEIGHT; ENERGY METABOLISM; GENE EXPRESSION REGULATION; LEPTIN; PHOTOPERIOD; SEASONS;

EID: 33746322135     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(06)53019-5     Document Type: Review

References (60)

1. Adam C.L., Moar K.M., Logie T.J., Ross A.W., Barrett P., Morgan P.J., and Mercer J.G. Photoperiod regulates growth, puberty and hypothalamic neuropeptide and receptor gene expression in female Siberian hamsters. Endocrinology 141 (2000) 4349-4356
2. Alder J., Thakker-Varia S., Bangasser D.A., Kuroiwa M., Plummer M.R., Shors T.J., and Black I.B. Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity. J. Neurosci. 23 (2003) 10800-10808
3. Arrang J.M., Garbarg M., and Schwartz J.C. Autoinhibition of histamine synthesis mediated by presynaptic H3-receptors. Neuroscience 23 (1987) 149-157
4. Atcha Z., Cagampang F.R., Stirland J.A., Morris I.D., Brooks A.N., Ebling F.J., Klingenspor M., and Loudon A.S. Leptin acts on metabolism in a photoperiod-dependent manner, but has no effect on reproductive function in the seasonally breeding Siberian hamster (Phodopus sungorus). Endocrinology 141 (2000) 4128-4135
5. Barrett P., Ross A.W., Balik A., Littlewood P.A., Mercer J.G., Moar K.M., Sallmen T., Kaslin J., Panula P., Schuhler S., Ebling F.J., Ubeaud C., and Morgan P.J. Photoperiodic regulation of histamine H3 receptor and VGF messenger ribonucleic acid in the arcuate nucleus of the Siberian hamster. Endocrinology 146 (2005) 1930-1939
6. Bartness T.J., Demas G.E., and Song C.K. Seasonal changes in adiposity: the roles of the photoperiod, melatonin and other hormones, and sympathetic nervous system. Exp. Biol. Med. (Maywood) 227 (2002) 363-376
7. Bartness T.J., Goldman B.D., and Bittman E.L. SCN lesions block responses to systemic melatonin infusions in Siberian hamsters. Am. J. Physiol. 260 (1991) R102-R112
8. Bartness T.J., and Wade G.N. Photoperiodic control of seasonal body weight cycles in hamsters. Neurosci. Biobehav. Rev. 9 (1985) 599-612
9. Berthoud H.R. Multiple neural systems controlling food intake and body weight. Neurosci. Biobehav. Rev. 26 (2002) 393-428
10. Bittman E.L., Bartness T.J., Goldman B.D., and DeVries G.J. Suprachiasmatic and paraventricular control of photoperiodism in Siberian hamsters. Am. J. Physiol. 260 (1991) R90-R101
11. Boss-Williams K.A., and Bartness T.J. NPY stimulation of food intake in Siberian hamsters is not photoperiod dependent. Physiol. Behav. 59 (1996) 157-164
12. Bowers R.R., Gettys T.W., Prpic V., Harris R.B., and Bartness T.J. Short photoperiod exposure increases adipocyte sensitivity to noradrenergic stimulation in Siberian hamsters. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288 (2005) R1354-R1360
13. Demas G.E., and Bartness T.J. Direct innervation of white fat and adrenal medullary catecholamines mediate photoperiodic changes in body fat. Am. J. Physiol. 281 (2001) R1499-R1505
14. Di Rocco G., Pennuto M., Illi B., Canu N., Filocamo G., Trani E., Rinaldi A.M., Possenti R., Mandolesi G., Sirinian M.I., Jucker R., Levi A., and Nasi S. Interplay of the E box, the cyclic AMP response element, and HTF4/HEB in transcriptional regulation of the neurospecific, neurotrophin-inducible vgf gene. Mol. Cell. Biol. 17 (1997) 1244-1253
15. Ebling F.J., Arthurs O.J., Turney B.W., and Cronin A.S. Seasonal neuroendocrine rhythms in the male Siberian hamster persist after monosodium glutamate-induced lesions of the arcuate nucleus in the neonatal period. J. Neuroendocrinol. 10 (1998) 701-712
16. Elmquist J.K., Maratos-Flier E., Saper C.B., and Flier J.S. Unraveling the central nervous system pathways underlying responses to leptin. Nat. Neurosci. 1 (1998) 445-450
17. Gorman M.R., and Zucker I. Seasonal adaptations of Siberian hamsters. II. Pattern of change in day length controls annual testicular and body weight rhythms. Biol. Reprod. 53 (1995) 116-125
18. Hahm S., Mizuno T.M., Wu T.J., Wisor J.P., Priest C.A., Kozak C.A., Boozer C.N., Peng B., McEvoy R.C., Good P., Kelley K.A., Takahashi J.S., Pintar J.E., Roberts J.L., Mobbs C.V., and Salton S.R. Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance. Neuron 23 (1999) 537-548
19. Hancock A.A., Diehl M.S., Fey T.A., Bush E.N., Faghih R., Miller T.R., Krueger K.M., Pratt J.K., Cowart M.D., Dickinson R.W., Shapiro R., Knourek-Segel V.E., Droz B.A., McDowell C.A., Krishna G., Brune M.E., Esbenshade T.A., and Jacobson P.B. Antiobesity evaluation of histamine H3 receptor (H3R) antagonist analogs of A-331440 with improved safety and efficacy. Inflamm. Res. 54 Suppl 1 (2005) S27-S29
20. Hofman M.A. The brain's calendar: neural mechanisms of seasonal timing. Biol. Rev. 79 (2004) 61-77
21. Johnston J.D., Ebling F.J., and Hazlerigg D.G. Photoperiod regulates multiple gene expression in the suprachiasmatic nuclei and pars tuberalis of the Siberian hamster (Phodopus sungorus). Eur. J. Neurosci. 21 (2005) 2967-2974
22. Klingenspor M., Dickopp A., Heldmaier G., and Klaus S. Short photoperiod reduces leptin gene expression in white and brown adipose tissue of Djungarian hamsters. FEBS Lett. 399 (1996) 290-294
23. Klingenspor M., Niggemann H., and Heldmaier G. Modulation of leptin sensitivity by short photoperiod acclimation in the Djungarian hamster, Phodopus sungorus. J. Comp. Physiol. [B] 170 (2000) 37-43
24. Knopper L.D., and Boily P. The energy budget of captive Siberian hamsters, Phodopus sungorus, exposed to photoperiod changes: mass loss is caused by a voluntary decrease in food intake. Physiol. Biochem. Zool. 73 (2000) 517-522
25. Levi A., Ferri .L., Watson E., Possenti R., and Salton S.R. Processing, distribution, and function of VGF, a neuronal and endocrine peptide precursor. Cell. Mol. Neurobiol. 24 (2004) 517-533
26. Lincoln G.A., Rhind S.M., Pompolo S., and Clarke I.J. Hypothalamic control of photoperiod-induced cycles in food intake, body weight, and metabolic hormones in rams. Am. J. Physiol. 281 (2001) R76-R90
27. Maffei M., Halaas J., Ravussin E., Pratley R.E., Lee G.H., Zhang Y., Fei, H., Kim S., Lallone R., Ranganathan S., Kern P.A., and Friedman J.M. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1 (1995) 1155-1161
28. Masuda A., and Oishi T. Effects of restricted feeding on the light-induced body weight change and locomotor activity in the Djungarian hamster. Physiol. Behav. 58 (1995) 153-159
29. Mercer J.G., Ellis C., Moar K.M., Logie T.J., Morgan P.J., and Adam C.L. Early regulation of hypothalamic arcuate nucleus CART gene expression by short photoperiod in the Siberian hamster. Regul. Peptides 111 (2003) 129-136
30. Mercer J.G., Lawrence C.B., Beck B., Burlet A., Atkinson T., and Barrett P. Hypothalamic NPY and prepro-NPY mRNA in Djungarian hamsters: effects of food deprivation and photoperiod. Am. J. Physiol. 269 (1995) R1099-R1106
31. Mercer J.G., Lawrence C.B., Moar K.M., Atkinson T., and Barrett P. Short-day weight loss and effect of food deprivation on hypothalamic NPY and CRF mRNA in Djungarian hamsters. Am. J. Physiol. 273 (1997) R768-R776
32. Mercer J.G., Moar K.M., Logie T.J., Findlay P.A., Adam C.L., and Morgan P.J. Seasonally inappropriate body weight induced by food restriction: effect on hypothalamic gene expression in male Siberian hamsters. Endocrinology 142 (2001) 4173-4181
33. Mercer J.G., Moar K.M., Ross A.W., Hoggard N., and Morgan P.J. Photoperiod regulates arcuate nucleus POMC, AGRP, and leptin receptor mRNA in Siberian hamster hypothalamus. Am. J. Physiol. 278 (2000) R271-R281
34. Messager S., Hazlerigg D.G., Mercer J.G., and Morgan P.J. Photoperiod differentially regulates the expression of Per1 and ICER in the pars tuberalis and the suprachiasmatic nucleus of the Siberian hamster. Eur. J. Neurosci. 12 (2000) 2865-2870
35. Messager S., Ross A.W., Barrett P., and Morgan P.J. Decoding photoperiodic time through Per1 and ICER gene amplitude. Proc. Natl. Acad. Sci. USA 96 (1999) 9938-9943
36. Morgan P.J., Barrett P., Howell H.E., and Helliwell R. Melatonin receptors: localization, molecular pharmacology and physioloigical significance. Neurochem. Int. 24 (1994) 101-146
37. Morgan P.J., and Mercer J.G. The regulation of body weight: lessons from the seasonal animal. Proc. Nutr. Soc. 60 (2001) 127-134
38. Morgan P.J., Ross A.W., Mercer J.G., and Barrett P. Photoperiodic programming of body weight through the neuroendocrine hypothalamus. J. Endocrinol. 177 (2003) 27-34
39. Morisset S., Rouleau A., Ligneau X., Gbahou F., Tardivel-Lacombe J., Stark H., Schunack W., Ganellin C.R., Schwartz J.C., and Arrang J.M. High constitutive activity of native H3 receptors regulates histamine neurons in brain. Nature 408 (2000) 860-864
40. Nagasaki K., Sasaki K., Maass N., Tsukada T., Hanzawa H., and Yamaguchi K. Staurosporine enhances cAMP-induced expression of neural-specific gene VGF and tyrosine hydroxylase. Neurosci. Lett. 267 (1999) 177-180
41. Nusselein-Hildesheim B., O'Brien J.A., Ebling F.J., Maywood E.S., and Hastings M.H. The circadian cycle of mPER clock gene products in the suprachiasmatic nucleus of the Siberian hamster encodes both daily and seasonal time. Eur. J. Neurosci. 12 (2000) 2856-2864
42. Reddy A.B., Cronin A.S., Ford H., and Ebling F.J. Seasonal regulation of food intake and body weight in the male Siberian hamster: studies of hypothalamic orexin (hypocretin), neuropeptide Y (NPY) and pro-opiomelanocortin (POMC). Eur. J. Neurosci. 11 (1999) 3255-3264
43. Robson A.J., Rousseau K., Loudon A.S., and Ebling F.J. Cocaine and amphetamine-regulated transcript mRNA regulation in the hypothalamus in lean and obese rodents. J. Neuroendocrinol. 14 (2002) 697-709
44. Ross A.W., Bell L.M., Littlewood P.A., Mercer J.G., Barrett P., and Morgan P.J. Temporal changes in gene expression in the arcuate nucleus precede seasonal responses in adiposity and reproduction. Endocrinology 146 (2005) 1940-1947
45. Ross A.W., Webster C.A., Mercer J.G., Moar K.M., Ebling F.J., Schuhler S., Barrett P., and Morgan P.J. Photoperiodic regulation of hypothalamic retinoid signaling: association of retinoid X receptor gamma with body weight. Endocrinology 145 (2004) 13-20
46. Rousseau K., Atcha Z., Cagampang F.R., Le Rouzic P., Stirland J.A., Ivanov T.R., Ebling F.J., Klingenspor M., and Loudon A.S. Photoperiodic regulation of leptin resistance in the seasonally breeding Siberian hamster (Phodopus sungorus). Endocrinology 143 (2002) 3083-3095
47. Sakata T., Yoshimatsu H., and Kurokawa M. Hypothalamic neuronal histamine: implications of its homeostatic control of energy metabolism. Nutrition 13 (1997) 403-411
48. Saper C.B., Chou T.C., and Elmquist J.K. The need to feed: homeostatic and hedonic control of eating. Neuron 36 (2002) 199-211
49. Scarpace P.J., Matheny M., Zhang Y., Shek E.W., Prima V., Zolotukhin S., and Tumer N. Leptin-induced leptin resistance reveals separate roles for the anorexic and thermogenic responses in weight maintenance. Endocrinology 143 (2002) 3026-3035
50. Schuhler S., Horan T.L., Hastings M.H., Mercer J.G., Morgan P.J., and Ebling F.J. Decrease of food intake by MC4-R agonist MTII in Siberian hamsters in long and short photoperiods. Am. J. Physiol. 284 (2003) R227-R232
51. Schuhler S., Horan T.L., Hastings M.H., Mercer J.G., Morgan P.J., and Ebling F.J. Feeding and behavioural effects of central administration of the melanocortin 3/4-R antagonist SHU9119 in obese and lean Siberian hamsters. Behav. Brain Res. 152 (2004) 177-185
52. Shi H., and Bartness T.J. Neurochemical phenotype of sympathetic nervous system outflow from brain to white fat. Brain Res. Bull. 54 (2001) 375-385
53. Song C.K., and Bartness T.J. Dorsocaudal SCN microknife-cuts do not block short day responses in Siberian hamsters given melatonin infusions. Brain Res. Bull 45 (1998) 239-246
54. Song C.K., and Bartness T.J. CNS sympathetic outflow neurons to white fat that express MEL receptors may mediate seasonal adiposity. Am. J. Physiol. 281 (2001) R666-R672
55. Steinlechner S., Heldmaier G., and Becker H. The seasonal cycle of body-weight in the Djungarian hamster - photoperiodic control and the influence of starvation and melatonin. Oecologia 60 (1983) 401-405
56. Takahashi K., Suwa H., Ishikawa T., and Kotani H. Targeted disruption of H3 receptors results in changes in brain histamine tone leading to an obese phenotype. J. Clin. Invest. 110 (2002) 1791-1799
57. Tups A., Ellis C., Moar K.M., Logie T.J., Adam C.L., Mercer J.G., and Klingenspor M. Photoperiodic regulation of leptin sensitivity in the Siberian hamster, Phodopus sungorus, is reflected in arcuate nucleus SOCS-3 (suppressor of cytokine signaling) gene expression. Endocrinology 145 (2004) 1185-1193
58. Wade G.N., and Bartness T.J. Effects of photoperiod and gonadectomy on food intake, body weight, and body composition in Siberian hamsters. Am. J. Physiol. 246 (1984) R26-R30
59. Yoshimatsu H., Chiba S., Tajima D., Akehi Y., and Sakata T. Histidine suppresses food intake through its conversion into neuronal histamine. Exp. Biol. Med. (Maywood) 227 (2002) 63-68
60. Yoshimatsu H., Itateyama E., Kondou S., Tajima D., Himeno K., Hidaka S., Kurokawa M., and Sakata T. Hypothalamic neuronal histamine as a target of leptin in feeding behavior. Diabetes 48 (1999) 2286-2291