-
1
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
Desvergne B, Wahli W (1999) Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 20: 649-688.
-
(1999)
Endocr Rev
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
2
-
-
23644456172
-
Therapeutic roles of peroxisome proliferator-activated receptor agonists
-
Staels B, Fruchart JC (2005) Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes 54: 2460-2470.
-
(2005)
Diabetes
, vol.54
, pp. 2460-2470
-
-
Staels, B.1
Fruchart, J.C.2
-
5
-
-
50649097541
-
Fat and beyond: The diverse biology of PPARγ
-
Tontonoz P, Spiegelman BM (2008) Fat and beyond: the diverse biology of PPARγ. Annu Rev Biochem 77: 289-312.
-
(2008)
Annu Rev Biochem
, vol.77
, pp. 289-312
-
-
Tontonoz, P.1
Spiegelman, B.M.2
-
7
-
-
33645863768
-
Transcriptional regulation of metabolism
-
Desvergne B, Michalik L, Wahli W (2006) Transcriptional regulation of metabolism. Physiol Rev 86: 465-514.
-
(2006)
Physiol Rev
, vol.86
, pp. 465-514
-
-
Desvergne, B.1
Michalik, L.2
Wahli, W.3
-
8
-
-
34548635236
-
Emerging roles of PPARδ in metabolism
-
Seedorf U, Aberle J (2007) Emerging roles of PPARδ in metabolism. Biochim Biophys Acta 1771: 1125-1131.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 1125-1131
-
-
Seedorf, U.1
Aberle, J.2
-
9
-
-
34547136480
-
New therapeutic target for metabolic syndrome: PPARδ
-
Takahashi S, Tanaka T, Sakai J (2007) New therapeutic target for metabolic syndrome: PPARδ. Endocr J 54: 347-357.
-
(2007)
Endocr J
, vol.54
, pp. 347-357
-
-
Takahashi, S.1
Tanaka, T.2
Sakai, J.3
-
10
-
-
39649101196
-
Activation of peroxisome proliferator-activated receptor (PPAR)δ promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men
-
Riserus U, Sprecher D, Johnson T, Olson E, Hirschberg S, et al. (2008) Activation of peroxisome proliferator-activated receptor (PPAR)δ promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men. Diabetes 57: 332-339.
-
(2008)
Diabetes
, vol.57
, pp. 332-339
-
-
Riserus, U.1
Sprecher, D.2
Johnson, T.3
Olson, E.4
Hirschberg, S.5
-
11
-
-
33846443997
-
Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor δ agonist
-
Sprecher DL, Massien C, Pearce G, Billin AN, Perlstein I, et al. (2007) Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor δ agonist. Arterioscler Thromb Vasc Biol 27: 359-365.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 359-365
-
-
Sprecher, D.L.1
Massien, C.2
Pearce, G.3
Billin, A.N.4
Perlstein, I.5
-
12
-
-
0036535037
-
Nuclear receptor corepressor-dependent repression of peroxisome-proliferator-activated receptor δ-mediated transactivation
-
Krogsdam AM, Nielsen CA, Neve S, Holst D, Helledie T, et al. (2002) Nuclear receptor corepressor-dependent repression of peroxisome-proliferator-activated receptor δ-mediated transactivation. Biochem J 363: 157-165.
-
(2002)
Biochem J
, vol.363
, pp. 157-165
-
-
Krogsdam, A.M.1
Nielsen, C.A.2
Neve, S.3
Holst, D.4
Helledie, T.5
-
13
-
-
0037022592
-
The peroxisome proliferator-activated receptor δ, an integrator of transcriptional repression and nuclear receptor signaling
-
Shi Y, Hon M, Evans RM (2002) The peroxisome proliferator-activated receptor δ, an integrator of transcriptional repression and nuclear receptor signaling. Proc Natl Acad Sci U S A 99: 2613-2618.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2613-2618
-
-
Shi, Y.1
Hon, M.2
Evans, R.M.3
-
14
-
-
0033599038
-
Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension
-
Barroso I, Gurnell M, Crowley VE, Agostini M, Schwabe JW, et al. (1999) Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension. Nature 402: 880-883.
-
(1999)
Nature
, vol.402
, pp. 880-883
-
-
Barroso, I.1
Gurnell, M.2
Crowley, V.E.3
Agostini, M.4
Schwabe, J.W.5
-
15
-
-
0035824652
-
Prostacyclin-dependent apoptosis mediated by PPARd
-
Hatae T, Wada M, Yokoyama C, Shimonishi M, Tanabe T (2001) Prostacyclin-dependent apoptosis mediated by PPARd. J Biol Chem 276: 46260-46267.
-
(2001)
J Biol Chem
, vol.276
, pp. 46260-46267
-
-
Hatae, T.1
Wada, M.2
Yokoyama, C.3
Shimonishi, M.4
Tanabe, T.5
-
16
-
-
24344502005
-
Selective expression of a dominant-negative form of peroxisome proliferator-activated receptor in keratinocytes leads to impaired epidermal healing
-
Michalik L, Feige JN, Gelman L, Pedrazzini T, Keller H, et al. (2005) Selective expression of a dominant-negative form of peroxisome proliferator-activated receptor in keratinocytes leads to impaired epidermal healing. Mol Endocrinol 19: 2335-2348.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 2335-2348
-
-
Michalik, L.1
Feige, J.N.2
Gelman, L.3
Pedrazzini, T.4
Keller, H.5
-
17
-
-
15744363183
-
A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein
-
Targett-Adams P, McElwee MJ, Ehrenborg E, Gustafsson MC, Palmer CN, et al. (2005) A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein. Biochim Biophys Acta 1728: 95-104.
-
(2005)
Biochim Biophys Acta
, vol.1728
, pp. 95-104
-
-
Targett-Adams, P.1
McElwee, M.J.2
Ehrenborg, E.3
Gustafsson, M.C.4
Palmer, C.N.5
-
18
-
-
0030952937
-
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
-
Forman BM, Chen J, Evans RM (1997) Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ. Proc Natl Acad Sci U S A 94: 4312-4317.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 4312-4317
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
19
-
-
0033615352
-
PPARd is an APC-regulated target of nonsteroidal anti-inflammatory drugs
-
He TC, Chan TA, Vogelstein B, Kinzler KW (1999) PPARd is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 99: 335-345.
-
(1999)
Cell
, vol.99
, pp. 335-345
-
-
He, T.C.1
Chan, T.A.2
Vogelstein, B.3
Kinzler, K.W.4
-
20
-
-
38749152401
-
Identification and characterization of a selective peroxisome proliferator-activated receptor β/δ (NR1C2) antagonist
-
Shearer BG, Steger DJ, Way JM, Stanley TB, Lobe DC, et al. (2008) Identification and characterization of a selective peroxisome proliferator-activated receptor β/δ (NR1C2) antagonist. Mol Endocrinol 22: 523-529.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 523-529
-
-
Shearer, B.G.1
Steger, D.J.2
Way, J.M.3
Stanley, T.B.4
Lobe, D.C.5
-
21
-
-
12444295462
-
Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling
-
Ide T, Shimano H, Yoshikawa T, Yahagi N, Amemiya-Kudo M, et al. (2003) Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling. Mol Endocrinol 17: 1255-1267.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1255-1267
-
-
Ide, T.1
Shimano, H.2
Yoshikawa, T.3
Yahagi, N.4
Amemiya-Kudo, M.5
-
22
-
-
12444256363
-
Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling
-
Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, et al. (2003) Cross-talk between peroxisome proliferator-activated receptor (PPAR) α and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling. Mol Endocrinol 17: 1240-1254.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1240-1254
-
-
Yoshikawa, T.1
Ide, T.2
Shimano, H.3
Yahagi, N.4
Amemiya-Kudo, M.5
-
23
-
-
33746905103
-
Ligand-activated PPARβ efficiently represses the induction of LXR-dependent promoter activity through competition with RXR
-
Matsusue K, Miyoshi A, Yamano S, Gonzalez FJ (2006) Ligand-activated PPARβ efficiently represses the induction of LXR-dependent promoter activity through competition with RXR. Mol Cell Endocrinol 256: 23-33.
-
(2006)
Mol Cell Endocrinol
, vol.256
, pp. 23-33
-
-
Matsusue, K.1
Miyoshi, A.2
Yamano, S.3
Gonzalez, F.J.4
-
24
-
-
0029417198
-
Thyroid hormone (T3) inhibits ciprofibrate-induced transcription of genes encoding β-oxidation enzymes: Cross talk between peroxisome proliferator and T3 signaling pathways
-
Chu R, Madison LD, Lin Y, Kopp P, Rao MS, et al. (1995) Thyroid hormone (T3) inhibits ciprofibrate-induced transcription of genes encoding β-oxidation enzymes: cross talk between peroxisome proliferator and T3 signaling pathways. Proc Natl Acad Sci U S A 92: 11593-11597.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 11593-11597
-
-
Chu, R.1
Madison, L.D.2
Lin, Y.3
Kopp, P.4
Rao, M.S.5
-
25
-
-
33947222099
-
Impaired adipogenesis caused by a mutated thyroid hormone a1 receptor
-
Ying H, Araki O, Furuya F, Kato Y, Cheng SY (2007) Impaired adipogenesis caused by a mutated thyroid hormone a1 receptor. Mol Cell Biol 27: 2359-2371.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2359-2371
-
-
Ying, H.1
Araki, O.2
Furuya, F.3
Kato, Y.4
Cheng, S.Y.5
-
26
-
-
28044438502
-
Thyroid hormone receptor β mutants: Dominant negative regulators of peroxisome proliferator-activated receptor γ action
-
Araki O, Ying H, Furuya F, Zhu X, Cheng SY (2005) Thyroid hormone receptor β mutants: Dominant negative regulators of peroxisome proliferator-activated receptor γ action. Proc Natl Acad Sci U S A 102: 16251-16256.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 16251-16256
-
-
Araki, O.1
Ying, H.2
Furuya, F.3
Zhu, X.4
Cheng, S.Y.5
-
28
-
-
0036140937
-
Diclofenac antagonizes peroxisome proliferator-activated receptor-c signaling
-
Adamson DJ, Frew D, Tatoud R, Wolf CR, Palmer CN (2002) Diclofenac antagonizes peroxisome proliferator-activated receptor-c signaling. Mol Pharmacol 61: 7-12.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 7-12
-
-
Adamson, D.J.1
Frew, D.2
Tatoud, R.3
Wolf, C.R.4
Palmer, C.N.5
-
29
-
-
0026785388
-
Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids
-
Schmidt A, Endo N, Rutledge SJ, Vogel R, Shinar D, et al. (1992) Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol Endocrinol 6: 1634-1641.
-
(1992)
Mol Endocrinol
, vol.6
, pp. 1634-1641
-
-
Schmidt, A.1
Endo, N.2
Rutledge, S.J.3
Vogel, R.4
Shinar, D.5
-
30
-
-
0032563863
-
Retinoid-X receptor signalling in the developing spinal cord
-
Solomin L, Johansson CB, Zetterstrom RH, Bissonnette RP, Heyman RA, et al. (1998) Retinoid-X receptor signalling in the developing spinal cord. Nature 395: 398-402.
-
(1998)
Nature
, vol.395
, pp. 398-402
-
-
Solomin, L.1
Johansson, C.B.2
Zetterstrom, R.H.3
Bissonnette, R.P.4
Heyman, R.A.5
-
31
-
-
0027459082
-
Retinoic acid receptors and retinoid X receptors: Interactions with endogenous retinoic acids
-
Allenby G, Bocquel MT, Saunders M, Kazmer S, Speck J, et al. (1993) Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids. Proc Natl Acad Sci U S A 90: 30-34.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 30-34
-
-
Allenby, G.1
Bocquel, M.T.2
Saunders, M.3
Kazmer, S.4
Speck, J.5
-
32
-
-
0032472408
-
Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor
-
Kalkhoven E, Valentine JE, Heery DM, Parker MG (1998) Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor. Embo J 17: 232-243.
-
(1998)
Embo J
, vol.17
, pp. 232-243
-
-
Kalkhoven, E.1
Valentine, J.E.2
Heery, D.M.3
Parker, M.G.4
-
33
-
-
0035941270
-
The peroxisome proliferator-activated receptor δ promotes lipid accumulation in human macrophages
-
Vosper H, Patel L, Graham TL, Khoudoli GA, Hill A, et al. (2001) The peroxisome proliferator-activated receptor δ promotes lipid accumulation in human macrophages. J Biol Chem 276: 44258-44265.
-
(2001)
J Biol Chem
, vol.276
, pp. 44258-44265
-
-
Vosper, H.1
Patel, L.2
Graham, T.L.3
Khoudoli, G.A.4
Hill, A.5
-
34
-
-
0028178229
-
Human AT1 receptor is a single copy gene: Characterization in a stable cell line
-
Aiyar N, Baker E, Wu HL, Nambi P, Edwards RM, et al. (1994) Human AT1 receptor is a single copy gene: characterization in a stable cell line. Mol Cell Biochem 131: 75-86.
-
(1994)
Mol Cell Biochem
, vol.131
, pp. 75-86
-
-
Aiyar, N.1
Baker, E.2
Wu, H.L.3
Nambi, P.4
Edwards, R.M.5
-
35
-
-
0023084134
-
Use of eukaryotic expression technology in the functional analysis of cloned genes
-
Cullen BR (1987) Use of eukaryotic expression technology in the functional analysis of cloned genes. Methods Enzymol 152: 684-704.
-
(1987)
Methods Enzymol
, vol.152
, pp. 684-704
-
-
Cullen, B.R.1
-
36
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ)
-
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, et al. (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). J Biol Chem 270: 12953-12956.
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
|