-
1
-
-
0027958441
-
+ channel is made of three homologous subunits
-
+ channel is made of three homologous subunits. Nature 1994; 367:463-7.
-
(1994)
Nature
, vol.367
, pp. 463-467
-
-
Canessa, C.M.1
Schild, L.2
Buell, G.3
-
2
-
-
4644268448
-
The epithelial sodium channel: From molecule to disease
-
Schild L. The epithelial sodium channel: from molecule to disease. Rev Physiol Biochem Pharmacol 2004; 151:93-107.
-
(2004)
Rev Physiol Biochem Pharmacol
, vol.151
, pp. 93-107
-
-
Schild, L.1
-
3
-
-
0346505482
-
New concepts of the pathogenesis of cystic fibrosis lung disease
-
Boucher RC. New concepts of the pathogenesis of cystic fibrosis lung disease. Eur Respir J 2004; 23:146-58.
-
(2004)
Eur Respir J
, vol.23
, pp. 146-158
-
-
Boucher, R.C.1
-
4
-
-
0035005503
-
Activation of epithelial sodium channels by prostasin in Xenopus oocytes
-
Adachi M, Kitamura K, Miyoshi T, et al. Activation of epithelial sodium channels by prostasin in Xenopus oocytes. J Am Soc Nephrol 2001; 12:1114-21.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 1114-1121
-
-
Adachi, M.1
Kitamura, K.2
Miyoshi, T.3
-
5
-
-
0030879756
-
An epithelial serine protease activates the amiloride-sensitive sodium channel
-
Vallet V, Chraibi A, Gaeggeler HP, et al. An epithelial serine protease activates the amiloride-sensitive sodium channel. Nature 1997; 389:607-10.
-
(1997)
Nature
, vol.389
, pp. 607-610
-
-
Vallet, V.1
Chraibi, A.2
Gaeggeler, H.P.3
-
6
-
-
17544386000
-
Activation of the amiloride-sensitive epithelial sodium channel by the serine protease mCAP1 expressed in a mouse cortical collecting duct cell line
-
Vuagniaux G, Vallet V, Jaeger NF, et al. Activation of the amiloride-sensitive epithelial sodium channel by the serine protease mCAP1 expressed in a mouse cortical collecting duct cell line. J Am Soc Nephrol 2000; 11:828-34. (Pubitemid 30241716)
-
(2000)
Journal of the American Society of Nephrology
, vol.11
, Issue.5
, pp. 828-834
-
-
Vuagniaux, G.1
Vallet, V.2
Jaeger, N.F.3
Pfister, C.4
Bens, M.5
Farman, N.6
Courtois-Coutry, N.7
Vandewalle, A.8
Rossier, B.C.9
Hummler, E.10
-
7
-
-
0036023427
-
Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid- regulated kinase (Sgk1) in Xenopus oocytes
-
DOI 10.1085/jgp.20028598
-
Vuagniaux G, Vallet V, Jaeger NF, et al. Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2 and mCAP3) and serum- and glucocorticoid-regulated kinase (Sgk1) in Xenopus Oocytes. J Gen Physiol 2002; 120:191-201. (Pubitemid 34857968)
-
(2002)
Journal of General Physiology
, vol.120
, Issue.2
, pp. 191-201
-
-
Vuagniaux, G.1
Vallet, V.2
Jaeger, N.F.3
Hummler, E.4
Rossier, B.C.5
-
8
-
-
0141621280
-
+ channel involves proteolytic processing of the a- and g-subunits
-
+ channel involves proteolytic processing of the a- and g-subunits. J Biol Chem 2003; 278:37073-82.
-
(2003)
J Biol Chem
, vol.278
, pp. 37073-37082
-
-
Hughey, R.P.1
Mueller, G.M.2
Bruns, J.B.3
-
9
-
-
2442427527
-
Epithelial sodium channels are activated by furin-dependent proteolysis
-
Hughey RP, Bruns JB, Kinlough CL, et al. Epithelial sodium channels are activated by furin-dependent proteolysis. J Biol Chem 2004; 279:18111-4.
-
(2004)
J Biol Chem
, vol.279
, pp. 18111-18114
-
-
Hughey, R.P.1
Bruns, J.B.2
Kinlough, C.L.3
-
10
-
-
0032698749
-
Aldosterone-mediated regulation of ENaC α, β and γ subunit proteins in rat kidney
-
Masilamani S, Kim GH, Mitchell C, et al. Aldosterone-mediated regulation of ENaC α, β and γ subunit proteins in rat kidney. J Clin Invest 1999; 104:19-23.
-
(1999)
J Clin Invest
, vol.104
, pp. 19-23
-
-
Masilamani, S.1
Kim, G.H.2
Mitchell, C.3
-
11
-
-
0034646199
-
A protein-based therapeutic for human cytomegalovirus infection
-
Jean F, Thomas L, Molloy SS, et al. A protein-based therapeutic for human cytomegalovirus infection. Proc Natl Acad Sci USA 2000; 97:2864-9.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2864-2869
-
-
Jean, F.1
Thomas, L.2
Molloy, S.S.3
-
12
-
-
0036791359
-
Furin at the cutting edge: From protein traffic to embryogenesis and disease
-
Thomas G. Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol 2002; 3:753-66.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 753-766
-
-
Thomas, G.1
-
14
-
-
0037462760
-
Structure of homo- and hetero-oligomeric meprin metalloproteases. Dimers, tetramers and high molecular mass multimers
-
Bertenshaw GP, Norcum MT, Bond JS. Structure of homo- and hetero-oligomeric meprin metalloproteases. Dimers, tetramers and high molecular mass multimers. J Biol Chem 2003; 278:2522-32.
-
(2003)
J Biol Chem
, vol.278
, pp. 2522-2532
-
-
Bertenshaw, G.P.1
Norcum, M.T.2
Bond, J.S.3
-
15
-
-
0029016839
-
The astacin family of metalloendopeptidases
-
Bond JS, Beynon RJ. The astacin family of metalloendopeptidases. Protein Sci 1995; 4:1247-61.
-
(1995)
Protein Sci
, vol.4
, pp. 1247-1261
-
-
Bond, J.S.1
Beynon, R.J.2
-
16
-
-
34247257873
-
The alpha and beta subunits of the metalloprotease meprin are expressed in separate layers of human epidermis, revealing different functions in keratinocyte proliferation and differentiation
-
Becker-Pauly C, Howel M, Walker T, et al. The alpha and beta subunits of the metalloprotease meprin are expressed in separate layers of human epidermis, revealing different functions in keratinocyte proliferation and differentiation. J Invest Dermatol 2007; 127:1115-25.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 1115-1125
-
-
Becker-Pauly, C.1
Howel, M.2
Walker, T.3
-
17
-
-
59749090413
-
Disruption of the meprin alpha and beta genes in mice alters homeostasis of monocytes and natural killer cells
-
Sun Q, Jin HJ, Bond JS. Disruption of the meprin alpha and beta genes in mice alters homeostasis of monocytes and natural killer cells. Exp Hematol 2009; 37:346-56.
-
(2009)
Exp Hematol
, vol.37
, pp. 346-356
-
-
Sun, Q.1
Jin, H.J.2
Bond, J.S.3
-
18
-
-
57649136396
-
Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway
-
Bergin DA, Greene CM, Sterchi EE, et al. Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway. J Biol Chem 2008; 283:31736-44.
-
(2008)
J Biol Chem
, vol.283
, pp. 31736-31744
-
-
Bergin, D.A.1
Greene, C.M.2
Sterchi, E.E.3
-
19
-
-
0035918152
-
Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity
-
Bertenshaw GP, Turk BE, Hubbard SJ, et al. Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity. J Biol Chem 2001; 276:13248-55.
-
(2001)
J Biol Chem
, vol.276
, pp. 13248-13255
-
-
Bertenshaw, G.P.1
Turk, B.E.2
Hubbard, S.J.3
-
20
-
-
4544377845
-
Transport of meprin subunits through the secretory pathway: Role of the transmembrane and cytoplasmic domains and oligomerization
-
Hengst JA, Bond JS. Transport of meprin subunits through the secretory pathway: role of the transmembrane and cytoplasmic domains and oligomerization. J Biol Chem 2004; 279:34856-64.
-
(2004)
J Biol Chem
, vol.279
, pp. 34856-34864
-
-
Hengst, J.A.1
Bond, J.S.2
-
21
-
-
52949132216
-
Meprins, membrane-bound and secreted astacin metalloproteinases
-
Sterchi EE, Stocker W, Bond JS. Meprins, membrane-bound and secreted astacin metalloproteinases. Mol Aspects Med 2008; 29:309-28.
-
(2008)
Mol Aspects Med
, vol.29
, pp. 309-328
-
-
Sterchi, E.E.1
Stocker, W.2
Bond, J.S.3
-
22
-
-
1542600151
-
-
Saklatvala J, Nagase H, Salvesen G, eds.
-
Villa JP, Bertenshaw GP, Bylander JE, Bond JS. In: Saklatvala J, Nagase H, Salvesen G, eds. Handbook of Biochemical Society Symposium. Proteases and the Regulation of Biological Processes 2003; 70:53-63.
-
(2003)
Handbook of Biochemical Society Symposium. Proteases and the Regulation of Biological Processes
, vol.70
, pp. 53-63
-
-
Villa, J.P.1
Bertenshaw, G.P.2
Bylander, J.E.3
Bond, J.S.4
-
23
-
-
0031017054
-
Identification of amino acid residues in the alpha, beta and gamma subunits of the epithelial sodium channel (ENaC) involved in amiloride block and ion permeation
-
DOI 10.1085/jgp.109.1.15
-
Schild L, Schneeberger E, Gautschi I, et al. Identification of amino acid residues in the alpha, beta and gamma subunits of the epithelial sodium channel (ENaC) involved in amiloride block and ion permeation. J Gen Physiol 1997; 109:15-26. (Pubitemid 27030190)
-
(1997)
Journal of General Physiology
, vol.109
, Issue.1
, pp. 15-26
-
-
Schild, L.1
Schneeberger, E.2
Gautschi, I.3
Firsov, D.4
-
24
-
-
0033844619
-
Differential subcellular localization of ENaC subunits in mouse kidney in response to high- and low-Na diets
-
Loffing J, Pietri L, Aregger F, et al. Differential subcellular localization of ENaC subunits in mouse kidney in response to high- and low-Na diets. Am J Physiol Renal Physiol 2000; 279:252-8.
-
(2000)
Am J Physiol Renal Physiol
, vol.279
, pp. 252-258
-
-
Loffing, J.1
Pietri, L.2
Aregger, F.3
-
25
-
-
0034527180
-
Differential regulation of ENaC by aldosterone in rat early and late distal colon
-
Amasheh S, Epple HJ, Mankertz J, et al. Differential regulation of ENaC by aldosterone in rat early and late distal colon. Ann NY Acad Sci 2000; 915:92-4. (Pubitemid 32059365)
-
(2000)
Annals of the New York Academy of Sciences
, vol.915
, pp. 92-94
-
-
Amasheh, S.1
Epple, H.J.2
Mankertz, J.3
Detjen, K.4
Goltz, M.5
Schulzke, J.D.6
Fromm, M.7
-
26
-
-
0344743590
-
A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel
-
DOI 10.1093/emboj/16.5.899
-
Grunder S, Firsov D, Chang SS, et al. A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel. EMBO J 1997; 16:899-907. (Pubitemid 27113169)
-
(1997)
EMBO Journal
, vol.16
, Issue.5
, pp. 899-907
-
-
Grunder, S.1
Firsov, D.2
Chang, S.S.3
Jaeger, N.F.4
Gautschi, I.5
Schild, L.6
Lifton, R.P.7
Rossier, B.C.8
-
27
-
-
0037040875
-
Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC)
-
DOI 10.1074/jbc.C100737200
-
Ma HP, Saxena S, Warnock DG. Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC). J Biol Chem 2002; 277:7641-4. (Pubitemid 34968207)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.10
, pp. 7641-7644
-
-
He-Ping, M.1
Saxena, S.2
Warnock, D.G.3
-
29
-
-
0027495896
-
Cloning, expression and chromosomal localization of the mouse meprin β subunit
-
Gorbea CM, Marchand P, Jiang W, et al. Cloning, expression and chromosomal localization of the mouse meprin β subunit. J Biol Chem 1993; 268:21035-43.
-
(1993)
J Biol Chem
, vol.268
, pp. 21035-21043
-
-
Gorbea, C.M.1
Marchand, P.2
Jiang, W.3
-
30
-
-
0027176126
-
Tissue-specific expression and chromosomal localization of the alpha subunit of mouse meprin A
-
Jiang W, Sadler PM, Jenkins NA, et al. Tissue-specific expression and chromosomal localization of the alpha subunit of mouse meprin A. J Biol Chem 1993; 268:10380-5.
-
(1993)
J Biol Chem
, vol.268
, pp. 10380-10385
-
-
Jiang, W.1
Sadler, P.M.2
Jenkins, N.A.3
-
31
-
-
0242384939
-
Phorbol 12-Myristate 13-Acetate-induced Ectodomain Shedding and Phosphorylation of the Human Meprinbeta Metalloprotease
-
DOI 10.1074/jbc.M211169200
-
Hahn D, Pischitzis A, Roesmann S, et al. Phorbol 12-myristate 13-acetate-induced ectodomain shedding and phosphorylation of the human meprinbeta metalloprotease. J Biol Chem 2003; 278:42829-39. (Pubitemid 37345893)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.44
, pp. 42829-42839
-
-
Hahn, D.1
Pischitzis, A.2
Roesmann, S.3
Hansen, M.K.4
Leuenberger, B.5
Luginbuehl, U.6
Sterchi, E.E.7
-
32
-
-
1642373361
-
Deletion of the Mouse Meprin β Metalloprotease Gene Diminishes the Ability of Leukocytes to Disseminate through Extracellular Matrix
-
Crisman JM, Zhang B, Norman LP, et al. Deletion of the mouse meprin β metalloprotease gene diminishes the ability of leukocytes to disseminate through extracellular matrix. J Immunol 2004; 172:4510-9. (Pubitemid 38375268)
-
(2004)
Journal of Immunology
, vol.172
, Issue.7
, pp. 4510-4519
-
-
Crisman, J.M.1
Zhang, B.2
Norman, L.P.3
Bond, J.S.4
-
33
-
-
0036849378
-
The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro
-
Guipponi M, Vuagniaux G, Wattenhofer M, et al. The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro. Hum Mol Genet 2002; 11:2829-36.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2829-2836
-
-
Guipponi, M.1
Vuagniaux, G.2
Wattenhofer, M.3
-
34
-
-
0036191884
-
Cell-surface expression of the channel activating protease xCAP-1 is required for activation of ENaC in the Xenopus oocyte
-
Vallet V, Pfister C, Loffing J, et al. Cell-surface expression of the channel activating protease xCAP-1 is required for activation of ENaC in the Xenopus oocyte. J Am Soc Nephrol 2002; 13:588-94.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 588-594
-
-
Vallet, V.1
Pfister, C.2
Loffing, J.3
-
35
-
-
0025991743
-
Meprin-A and -B. Cell surface endopeptidases of the mouse kidney
-
Kounnas MZ, Wolz RL, Gorbea CM, et al. Meprin-A and -B. Cell surface endopeptidases of the mouse kidney. J Biol Chem 1991; 266:17350-7.
-
(1991)
J Biol Chem
, vol.266
, pp. 17350-17357
-
-
Kounnas, M.Z.1
Wolz, R.L.2
Gorbea, C.M.3
-
36
-
-
0037072881
-
A selective interaction between OS-9 and the carboxyl-terminal tail of meprin beta
-
Litovchick L, Friedmann E, Shaltiel S. A selective interaction between OS-9 and the carboxyl-terminal tail of meprin beta. J Biol Chem 2002; 277:34413-23.
-
(2002)
J Biol Chem
, vol.277
, pp. 34413-34423
-
-
Litovchick, L.1
Friedmann, E.2
Shaltiel, S.3
-
37
-
-
13944276440
-
OS-9 interacts with hypoxia-inducible factor 1α and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1α
-
DOI 10.1016/j.molcel.2005.01.011
-
Baek JH, Mahon PC, Oh J, et al. OS-9 interacts with hypoxia-inducible factor 1α and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1α. Mol Cell 2005; 17:503-12. (Pubitemid 40269115)
-
(2005)
Molecular Cell
, vol.17
, Issue.4
, pp. 503-512
-
-
Baek, J.H.1
Mahon, P.C.2
Oh, J.3
Kelly, B.4
Krishnamachary, B.5
Pearson, M.6
Chan, D.A.7
Giaccia, A.J.8
Semenza, G.L.9
-
39
-
-
24944507963
-
Meprin beta metalloprotease gene polymorphisms associated with diabetic nephropathy in the Pima Indians
-
Red Eagle AR, Hanson RL, Jiang W, et al. Meprin beta metalloprotease gene polymorphisms associated with diabetic nephropathy in the Pima Indians. Hum Genet 2005; 118:12-22.
-
(2005)
Hum Genet
, vol.118
, pp. 12-22
-
-
Red Eagle, A.R.1
Hanson, R.L.2
Jiang, W.3
-
40
-
-
0028982894
-
CFTR as a cAMP-dependent regulator of sodium channels
-
Stutts MJ, Canessa CM, Olsen JC, et al. CFTR as a cAMP-dependent regulator of sodium channels. Science 1995; 269:847-50.
-
(1995)
Science
, vol.269
, pp. 847-850
-
-
Stutts, M.J.1
Canessa, C.M.2
Olsen, J.C.3
-
42
-
-
0035119671
-
Angiotensin AT(1) receptor phosphorylation and desensitization in a hepatic cell line. Roles of protein kinase c and phosphoinositide 3-kinase
-
Garcia-Caballero A, Olivares-Reyes JA, Catt KJ, et al. Angiotensin AT(1) receptor phosphorylation and desensitization in a hepatic cell line. Roles of protein kinase c and phosphoinositide 3-kinase. Mol Pharmacol 2001; 59:576-85.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 576-585
-
-
Garcia-Caballero, A.1
Olivares-Reyes, J.A.2
Catt, K.J.3
-
43
-
-
2942754004
-
Heterogeneous nuclear ribonuclear protein U associates with YAP and regulates its co-activation of Bax transcription
-
Howell M, Borchers C, Milgram SL. Heterogeneous nuclear ribonuclear protein U associates with YAP and regulates its co-activation of Bax transcription. J Biol Chem 2004; 279:26300-6.
-
(2004)
J Biol Chem
, vol.279
, pp. 26300-26306
-
-
Howell, M.1
Borchers, C.2
Milgram, S.L.3
-
44
-
-
0037040995
-
Regulation of the epithelial sodium channel by serine proteases in human airways
-
Donaldson SH, Hirsh A, Li DC, et al. Regulation of the epithelial sodium channel by serine proteases in human airways. J Biol Chem 2002; 277:8338-45.
-
(2002)
J Biol Chem
, vol.277
, pp. 8338-8345
-
-
Donaldson, S.H.1
Hirsh, A.2
Li, D.C.3
-
45
-
-
0035933819
-
Multimeric structure of the secreted meprin a metalloproteinase and characterization of the functional protomer
-
Ishmael FT, Norcum MT, Benkovic SJ, et al. Multimeric structure of the secreted meprin A metalloproteinase and characterization of the functional protomer. J Biol Chem 2001; 276:23207-11.
-
(2001)
J Biol Chem
, vol.276
, pp. 23207-23211
-
-
Ishmael, F.T.1
Norcum, M.T.2
Benkovic, S.J.3
-
46
-
-
0037317483
-
Targeted disruption of the meprin beta gene in mice leads to underrepresentation of knockout mice and changes in renal gene expression profiles
-
Norman LP, Jiang W, Han X, et al. Targeted disruption of the meprin beta gene in mice leads to underrepresentation of knockout mice and changes in renal gene expression profiles. Mol Cell Biol 2003; 23:1221-30.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1221-1230
-
-
Norman, L.P.1
Jiang, W.2
Han, X.3
|