Marked Differences between Metalloproteases Meprin A and B in Substrate and Peptide Bond Specificity

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 13248-13255

  Bertenshaw, Greg P ^a   Turk, Benjamin E ^b,c   Hubbard, Simon J ^d   Matters, Gail L ^a   Bylander, John E ^a   Crisman, Jacqueline M ^a   Cantley, Lewis C ^b,c   Bond, Judith S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CATALYST SELECTIVITY; CELLS; CHEMICAL BONDS; CRYSTAL STRUCTURE; HYDROLYSIS; METALLORGANIC POLYMERS; REACTION KINETICS; TISSUE;

PEPTIDES;

ENZYMES;

ALANINE; ASTACIN; GASTRIN 17; GASTRIN RELEASING PEPTIDE[14-27]; MEPRIN; MEPRIN B; METALLOPROTEINASE; OLIGOMER; PEPTIDE; PEPTIDE FRAGMENT; PEPTIDE LIBRARY; PHENYLALANINE; PROTEIN SUBUNIT; SERINE; UNCLASSIFIED DRUG; HORMONE;

ARTICLE; CELL SURFACE; CHEMICAL BOND; CRYSTAL STRUCTURE; ENZYME KINETICS; ENZYME RELEASE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBUNIT; GASTROINTESTINAL TRACT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN HYDROLYSIS; PROTEIN LOCALIZATION; SEQUENCE HOMOLOGY; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; C3H MOUSE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ENZYMOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; KIDNEY; KINETICS; METABOLISM; MICROVILLUS; MOLECULAR GENETICS; PROTEIN CONFORMATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; HORMONES; KIDNEY; KINETICS; MALE; METALLOENDOPEPTIDASES; MICE; MICE, INBRED C3H; MICE, INBRED ICR; MICROVILLI; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PEPTIDES; PROTEIN CONFORMATION; PROTEIN SUBUNITS; SUBSTRATE SPECIFICITY;

EID: 0035918152     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011414200     Document Type: Article

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