Autologous transplantation of retrovirally transduced bone marrow or neonatal blood cells into cats can lead to long-term engraftment in the absence of myeloablation

Gene Therapy

Volumn 6, Issue 1, 1999, Pages 107-113

  Simonaro, C M ^a   Haskins, M E ^b   Abkowitz, J L ^c   Brooks, D A ^d   Hopwood, J J ^d   Zhang, J ^a   Schuchman, E H ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d WOMEN S AND CHILDREN S HOSPITAL   (Australia)

Author keywords

Animal models; Hematopoeitic stem cell gene therapy; Mucopolysaccaridosis type VI; Retrovirus mediated gene transfer

Indexed keywords

COMPLEMENTARY DNA; MYELOABLATIVE AGENT; N ACETYLGALACTOSAMINE 4 SULFATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; AUTOTRANSPLANTATION; BONE MARROW CELL; CAT; ENZYME ACTIVITY; GENE TARGETING; GENETIC CODE; GENETIC TRANSDUCTION; GRANULOCYTE; HEMATOPOIETIC STEM CELL; LYMPHOCYTE; LYSOSOME STORAGE DISEASE; MAROTEAUX LAMY SYNDROME; NEWBORN; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROVIRUS; RETROVIRUS; WHOLE BODY RADIATION;

ANIMALS; ANIMALS, NEWBORN; BONE MARROW TRANSPLANTATION; CATS; GENE THERAPY; GENETIC VECTORS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; MUCOPOLYSACCHARIDOSIS VI; N-ACETYLGALACTOSAMINE-4-SULFATASE; RETROVIRIDAE; TIME FACTORS; TRANSFECTION; TRANSPLANTATION, AUTOLOGOUS;

ANIMALIA; FELIDAE; FELIS CATUS; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0032922212     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300797     Document Type: Article

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