Reversibility of proliferative lesions and induction of non-papillary tumors in rat urinary bladder treated with phenylethyl isothiocyanate

Carcinogenesis

Volumn 24, Issue 3, 2003, Pages 547-553

  Sugiura, Satoshi ^a   Ogawa, Kumiko ^a   Hirose, Masao ^b   Takeshita, Fumitaka ^a   Asamoto, Makoto ^a   Shirai, Tomoyuki ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CARCINOGEN; ONCOPROTEIN; PHENETHYL ISOTHIOCYANATE; PROTEIN P53;

ADENOCARCINOMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CARCINOGENESIS; BLADDER EPITHELIUM; BLADDER PAPILLOMA; CANCER INCIDENCE; CELL DIFFERENTIATION; CELL TYPE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG WITHDRAWAL; DYSPLASIA; GENE MUTATION; LABELING INDEX; MALE; NODULAR HYPERPLASIA; NONHUMAN; ONCOGENE H RAS; POINT MUTATION; PRIORITY JOURNAL; RAT; RAT STRAIN; SQUAMOUS CELL; UROTHELIUM;

ANIMALS; BASE SEQUENCE; CARCINOGENS; CELL DIVISION; DNA PRIMERS; ISOTHIOCYANATES; MALE; RATS; RATS, INBRED F344; URINARY BLADDER; URINARY BLADDER NEOPLASMS;

EID: 0037357453     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/24.3.547     Document Type: Article

References (40)

1. VanEtten,C.H., Daxenbichler,M.E., Williams,P.H. and Kwolek,W.F. (1976) Glucosinolates and derived products in cruciferous vegetables. Analysis of the edible part from twenty-two varieties of cabbage. J. Agric. Food Chem., 24, 452-455.
2. Sones,K., Heaney,R.K. and Fenwick,G.R. (1984) An estimate of the mean daily intake of glucosinolates from cruciferous vegetables in the UK. J. Sci. Food Agric., 35, 712-720.
3. Wattenberg,L.W. (1977) Inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds. J. Natl Cancer Inst., 58, 395-398.
4. Stoner,G.D., Morrissey,D.T., Heur,Y-H., Daniel,E.M., Galati,A.J. and Wagner,S.A. (1991) Inhibitory effects of phenethyl isothiocyanate on N-nitrosobenzylmethylamine carcinogenesis in the rat esophagus. Cancer Res., 51, 2063-2068.
5. Siglin,J.C., Barch,D.H. and Stoner,G.D. (1995) Effects of dietary phenethyl isothiocyanate, ellagic acid, sulindac and calcium on the induction and progression of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats. Carcinogenesis, 16, 1101-1106.
6. Wilkinson,J.T., Morse,M.A., Kresty,L.A. and Stoner,G.D. (1995) Effect of alkyl chain length on inhibition of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis and DNA methylation by isothiocyanates. Carcinogenesis, 16, 1011-1015.
7. Morse,M.A., Wang,C.-X., Stoner,G.D., Mandal,S., Conran,P.B., Amin,S.G., Hecht,S.S. and Chung,F.-L. (1989) Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation and tumorigenicity in the lung of F344 rats by dietary phenyl isothiocyanate. Cancer Res., 49, 549-553.
8. 6-methylguanine formation and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung. Cancer Res., 49, 2894-2897.
9. Ishizaki,H., Brady,J.F., Ning,S.M. and Yang,C.S. (1990) Effect of phenethyl isothiocyanate on microsomal N-nitrosodimethylamine metabolism and other monooxygenase activities. Xenobiotica, 20, 255-264.
10. Hamilton,S.M., Zhang,Z. and Teel,R.W. (1994) Effects of isothiocyanate alkyl chain-length on hamster liver cytochrome P-450 activity. Cancer Lett., 82, 217-224.
11. Morse,M.A., Eklind,K.I., Hecht,S.S. and Chung,F.L. (1991) Inhibition of tobacco-specific nitrosamine 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) tumorigenesis with aromatic isothiocyanates. IARC Scientific Publications, IARC, Lyon, Vol. 105, pp. 529-534.
12. Zhang,Y. and Talalay,P. (1994) Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms. Cancer Res., 54 (suppl.), 1976s-1981s.
13. Ogawa,K., Futakuchi,M., Hirose,M., Boonyaphiphat,P., Mizoguchi,Y., Miki,T. and Shirai,T. (1998) Stage and organ dependent effects of 1-O-hexyl-2,3,5-trimethylhydroquinone, ascorbic acid derivatives, n-hepta-decane-8,10-dione and phenylethyl isothiocyanate in a rat multiorgan carcinogenesis model. Int. J. Cancer, 76, 851-856.
14. Hirose,M., Yamaguchi,T., Kimoto,N., Ogawa,K., Futakuchi,M., Sano,M. and Shirai,T. (1998) Strong promoting activity of phenylethyl isothiocyanate and benzyl isothiocyanate on urinary bladder carcinogenesis in F344 male rats. Int. J. Cancer, 77, 773-777.
15. Ogawa,K., Hirose,M., Sugiura,S., Cui,L., Imaida,K., Ogiso,T. and Shirai,T. (2001) Dose-dependent promotion by phenylethyl isothiocyanate, a known chemopreventer, of two-stage rat urinary bladder and liver carcinogenesis. Nutr. Cancer, 40, 134-139.
16. Musk,S.R. and Johnson,I.T. (1993) The clastogenic effects of isothiocyanates. Mutat. Res., 300, 111-117.
17. Musk,S.R., Smith,T.K. and Johnson,I.T. (1995) On the cytotoxicity and genotoxicity of allyl and phenethyl isothiocyanates and their parent glucosinolates sinigrin and gluconasturtiin. Mutat. Res., 348, 19-23.
18. Kassie,F. and Knasmüller,S. (2000) Genotoxic effects of allyl isothiocyanate (AITC) and phenethyl isothiocyanate (PEITC). Chem.-Biol. Interact., 127, 163-180.
19. Shirai,T., Tagawa,Y., Fukushima,S., Imaida,K. and Ito,N. (1987) Strong promoting activity of reversible uracil-induced urolithiasis on urinary bladder carcinogenesis in rats initiated with N-butyl-N-(4-hydroxy-butyl) nitrosamine. Cancer Res., 47, 6726-6730.
20. Kagawa,M., Hakoi,K., Yamamoto,A., Futakuchi,M. and Hirose,M. (1993) Comparison of reversibility of rat forestomach lesions induced by genotoxic and non-genotoxic carcinogens. Jpn. J. Cancer Res., 84, 1120-1129.
21. Sidransky,D., Von Eschenbach,A., Tsai,Y.C. et al. (1991) Identification of p53 gene mutations in bladder cancers and urine samples. Science, 152, 706-709.
22. Fujimoto,K., Yamada,Y., Okajima,E., Kakizoe,T., Sasaki,H., Sugimura,T. and Terada,M. (1992) Frequent association of p53 gene mutation in invasive bladder cancer. Cancer Res., 52, 1393-1398.
23. Kusser,W.C., Miao,X., Glickman,B.W., Friedland,J.M., Rothman,N., Hemstreet,G.P., Mellot,J., Swan,D.C., Schulte,P.A. and Hayes,R.B. (1994) p53 mutations in human bladder cancer. Environ. Mol. Mutagen., 24, 156-160.
24. Spruck III,C.H., Ohneseit,P.F., Gonzalez-Zulueta,M. et al. (1994) Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res., 54, 784-788.
25. Asamoto,M., Mann,A.M. and Cohen,S.M. (1994) p53 mutation is infrequent and might not give a growth advantage in rat bladder carcinogenesis in vivo. Carcinogenesis, 15, 455-458.
26. Masui,T., Don,I., Takada,N., Ogawa,K., Shirai,T. and Fukushima,S. (1994) p53 mutations in early neoplastic lesions of the urinary bladder in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine. Carcinogenesis, 15, 2379-2381.
27. Yamamoto,K., Nakata,D., Tada,M. et al. (1999) A functional and quantitative mutational analysis of p53 mutations in yeast indicates strand biases and different roles of mutations in DMBA- and BBN-induced tumors in rats [published erratum appears in Int. J. Cancer, 2000; 85: 898]. Int. J. Cancer, 83, 700-705.
28. Ito,N., Hiasa,Y., Tamai,A., Okajima,E. and Kitamura,H. (1969) Histogenesis of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in rats. Gann, 60, 401-410.
29. Akagi,G., Akagi,A., Kimura,M. and Otsuka,H. (1973) Comparison of bladder tumors induced in rats and mice with N-butyl-N-(4-hydroxybutyl) nitrosoamine. Gann, 64, 331-336.
30. Ertürk,E., Cohen,S.M. and Bryan,G.T. (1970) Urinary bladder carcinogenicity of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in female Swiss mice. Cancer Res., 30, 1309-1311.
31. Cohen,S.M., Ellwein,L.B., Okamura,T. et al. (1991) Comparative bladder tumor promoting activity of sodium saccharin, sodium ascorbate, related acids and calcium salts in rats. Cancer Res., 51, 1766-1777.
32. Ito,N., Hirose,M., Shibata,M., Tanaka,H. and Shirai,T. (1989) Modifying effects of simultaneous treatment with butylated hydroxyanisole (BHA) on rat tumor induction by 3,2′-dimethyl-4-aminobiphenyl, 2,2′-dihydroxydi-n-propylnitrosamine and N-methylnitrosourea. Carcinogenesis, 10, 2255-2259.
33. Yang,Y.M., Conaway,C.C., Chiao,J.W., Wang,C.X., Amin S., Whysner,J., Dai,W., Reinhardt,J. and Chung,F.L. (2002) Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis. Cancer Res., 62, 2-7.
34. Dunnick,J.K., Prejean,J.D., Haseman,J., Thompson,R.B., Giles,H.D. and McConnell,E.E. (1982) Carcinogenesis bioassay of allyl isothiocyanate. Fund. Appl. Toxicol., 2, 114-120.
35. Cohen,S.M., Jacobs,J.B., Arai,M., Johansson,S. and Friedell,G.H. (1976) Early lesions in experimental bladder cancer: experimental design and light microscopic findings. Cancer Res., 36, 2508-2511.
36. Nakamura,Y., Ohigashi,H., Masuda,S., Murakami,A., Morimitsu,Y., Kawamoto,Y., Osawa,T., Imagawa,M. and Uchida,K. (2000) Redox regulation of glutathione S-transferase induction by benzyl isothiocyanate: correlation of enzyme induction with the formation of reactive oxygen intermediates. Cancer Res., 60, 219-225.
37. Murata,M., Yamashita,N., Inoue,S. and Kawanishi,S. (2000) Mechanism of oxidative DNA damage induced by carcinogenic allyl isothiocyanate. Free Radic. Biol. Med., 28, 797-805.
38. Ertük,E., Price,J.M., Morris,J.E., Cohen,S., Leith,R.S., Von Esch,A.N. and Crovetti,A.J. (1967) The production of carcinoma of the urinary bladder in rats by feeding N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. Cancer Res., 27, 1998-2002.
39. Fukushima,S., Tanaka,H., Asakawa,E., Kagawa,M., Yamamoto,A. and Shirai,T. (1992) Carcinogenicity of uracil, a nongenotoxic chemical, in rats and mice and its rationale. Cancer Res., 52, 1675-1680.
40. 1 mice as a useful model for study of chemoprevention of cancer with retinoids. Cancer Res., 41, 927-932.