Antibodies from a DNA peptide vaccination decrease the brain amyloid burden in a mouse model of Alzheimer's disease

Journal of Molecular Medicine

Volumn 82, Issue 10, 2004, Pages 706-714

  Schultz, Jan G ^a,c   Salzer, Ulrich ^a,b,d   Mohajeri, M Hasan ^a,e   Franke, Daniel ^a   Heinrich, Jochen ^a   Pavlovic, Jovan ^a   Wollmer, M Axel ^a   Nitsch, Roger M ^a   Moelling, Karin ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF FREIBURG   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e SWISS FEDERAL INSTITUTE OF TECHNOLOGY   (Switzerland)

Author keywords

Alzheimer's disease; DNA vaccine; Monoclonal antibodies

Indexed keywords

ALANINE; ALZHEIMER DISEASE VACCINE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[1-42] MONOCLONAL ANTIBODY; AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN; ANTISERUM; ASPARTIC ACID; DNA VACCINE; GENE PRODUCT; GLUTAMINE; MONOCLONAL ANTIBODY; PHENYLALANINE; PLASMID DNA; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ACTIVE IMMUNIZATION; ADOLESCENT; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; EPITOPE MAPPING; IN VITRO STUDY; INFLAMMATION; MOUSE; NEUROPATHOLOGY; NONHUMAN; PASSIVE IMMUNIZATION; SENILE PLAQUE; SOLUBILIZATION; TRANSGENIC MOUSE; VACCINATION;

ALZHEIMER DISEASE; ALZHEIMER VACCINES; AMYLOID BETA-PROTEIN; ANIMALS; ANTIBODIES; ANTIBODIES, MONOCLONAL; BRAIN; CERCOPITHECUS AETHIOPS; COS CELLS; DISEASE MODELS, ANIMAL; DNA; EPITOPES; HUMANS; IMMUNIZATION, PASSIVE; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; PEPTIDES; VACCINATION; VACCINES, SYNTHETIC;

EID: 7944236860     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-004-0570-z     Document Type: Article

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