Effect of artemether alone and in combination with grapefruit juice on hepatic drug-metabolising enzymes and biochemical aspects in experimental Schistosoma mansoni

International Journal for Parasitology

Volumn 34, Issue 12, 2004, Pages 1405-1412

  El Lakkany, N M ^a   Seif El Din, S H ^a   Badawy, A A ^b   Ebeid, F A ^a  

^a Giza   (Egypt)

^b Imbaba   (Egypt)

Author keywords

Artemether; Cytochrome b5; Cytochrome P 450; Grapefruit juice; Schistosoma mansoni

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ANTIPARASITIC AGENT; ARTEMETHER; CYTOCHROME B5; CYTOCHROME P450; DRUG METABOLIZING ENZYME; GLOBULIN; LIVER ENZYME;

PARASITE CONTROL; SCHISTOSOMIASIS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SCREENING; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INHIBITION; FEMALE; GRAPE JUICE; HISTOPATHOLOGY; LIVER GRANULOMA; MALE; MOUSE; NONHUMAN; SCHISTOSOMA MANSONI; TREMATODIASIS; WORM INFECTION;

ANIMALS; ANTIMALARIALS; ARTEMISININS; BEVERAGES; CITRUS PARADISI; CYTOCHROME P-450 ENZYME SYSTEM; CYTOCHROMES B5; FOOD-DRUG INTERACTIONS; LIVER; LIVER FUNCTION TESTS; MALE; MICE; MICE, INBRED STRAINS; MODELS, ANIMAL; SCHISTOSOMIASIS MANSONI; SESQUITERPENES;

CITRUS X PARADISI; SCHISTOSOMA; SCHISTOSOMA MANSONI;

EID: 7944227595     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2004.08.012     Document Type: Article

References (48)

1. O.M. Abdallahi, S. Hanna, M. De Reggi, and B. Gharib Visualization of oxygen radical production in mouse liver in response to infection with Schistosoma mansoni Liver 19 1999 495 500
2. S.S. Abdel Aziz, and N.M. El-Badawy Experimental trials of an artemisinin derivative in treatment of Schistosoma mansoni infected mice J. Egypt. Soc. Parasitol. 30 2000 295 303
3. A.F. Badawi, and M.H. Mostafa Possible mechanisms of alteration in the capacity of carcinogen-metabolising enzymes during schistosomiasis J. Int. Med. Res. 21 1993 281 305
4. D.G. Bailey, J. Malcolm, O. Arnold, and J.D. Spence Grapefruit juice-drug interactions Br. J. Clin. Pharmacol. 46 1998 101 110
5. Y. Cai, W. Bear-Dubowska, M.J. Ashwood-Smith, O. Ceska, S. Tachibana, and J. DiGiovanni Mechanism-based inactivation of hepatic ethoxyresorufin O-dealkylation activity by naturally occurring coumarins Chem. Res. Toxicol. 9 1996 729 736
6. D. Cioli Chemotherapy of schistosomiasis: an update Parasitol. Today 14 1998 418 422
7. D. Cioli Praziquantel: is there real resistance and are there alternatives? Curr. Opin. Infect. Dis. 13 2000 659 663
8. J.N.M. Commandeur, and N.P.E. Vermeulen Molecular and biochemical mechanisms of chemically induced nephrotoxicity: a review Chem. Res. Toxicol. 3 1990 485 491
9. A. Danso-Appiah, and S.J. De Vlas Interpreting low praziquantel cure rates of Schistosoma mansoni infections in Senegal Trends Parasitol. 18 2002 125 129
10. M.J. Doenhoff, J.R. Kusel, G.C. Coles, and D. Cioli Resistance of Schistosoma mansoni to praziquantel: is there a problem? Trans. R. Soc. Trop. Med. Hyg. 96 2002 465 469
11. B.T. Doumas, W.R. Watson, and H.G. Biggs Albumin standard and measurement of serum albumin with bromocresol green Clin. Chem. Acta 31 1971 87 96
12. R.H. Duvall, and W.B. De Witt Technique for recovering adult schistosomes from laboratory animals Am. J. Trop. Med. Hyg. 16 1967 438 486
13. F.A. Ebeid, S.H. Seif el-Din, and A.R. Ezzat Effect of Schistosoma mansoni infection and treatment on drug-metabolising enzymes Arzneim. Forschung/Drug Res. 50 II 2000 867 874
14. D.J. Edwards, F.H. Bellevue, and P.M. Woster Identification of 6′,7′-dihydroxybergamottin, a cytochrome P-450 inhibitor in grapefruit juice Drug Metab. Dispos. 24 1996 128 129
15. H. Fouin-Fortunet, M. Tinel, V. Descatoire, P. Lettern, D. Lerrey, J. Geneve, and D. Pessayre Inactivation of cytochrome P-450 by the drug methoxalen J. Pharmacol. Exp. Ther. 236 1986 237 247
16. K. Fukuda, T. Ohta, and Y. Yamazoe Grapefruit component interacting with rat and human P-450 CYP3A: possible involvement of non-flavonoid components in drug interaction Biol. Pharm. Bull. 20 1997 560 564
17. B. Gryseels, A. Mbaye, S.J. De Vlas, F.F. Stelma, F. Guissé, L. Van Lieshout, D. Faye, M. Diop, A. Ly, L.A. Tchuem-Tchuenté, D. Engels, and K. Polman Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence Trop. Med. Int. Health 6 2001 864 873
18. R.Z. Harris, G.R. Jang, and S. Tsunoda Dietary effects on drug metabolism and transport Clin. Pharmacokinet. 42 2003 1071 1088
19. P.C. Ho, D.J. Saville, P.C. Coville, and S. Wanwimolruk Content of CYP3A4 inhibitors, naringin, naringinin and bergapten in grapefruit and grapefruit juice products Pharmaceut. Acta Helv. 74 2000 379 385
20. P.C. Ho, D.J. Saville, and S. Wanwimolruk Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds J. Pharm. Pharmaceut. Sci. 4 2001 217 227
21. I.A. Kamel, A.W. Cheever, A.M. Elwi, J.E. Mosimann, and R. Danner Schistosoma mansoni and S. haematobium infections in Egypt: technique for recovery of worms at necropsy Am. J. Trop. Med. Hyg. 26 1977 696 701
22. S. Kanno, A. Shouji, K. Asou, and M. Ishikawa Effect of naringin on hydrogen peroxide-induced cytotoxicity and apoptosis in p388 cells J. Pharmacol. Sci. 92 2003 166 170
23. J.C. Kolars, P. Schmiedlin-Ren, J.D. Schuetz, C. Fang, and P.B. Watkins Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes J. Clin. Invest. 90 1878 1871 1878
24. ®) with concomitant administration of ketoconazole in healthy subjects Br. J. Clin. Pharmacol. 54 2002 485 492
25. Y.S. Liang, B.I. John, and D.A. Boyed Laboratory cultivation of schistosome vector snails and maintenance of schistosome life cycles Proceeding of the First Sino-American Symposium vol. 1 1987 p. 34
26. K.S. Lown, D.G. Bailey, R.J. Fontana, S.K. Janardan, C.H. Adair, L.A. Fortlage, M.B. Brown, W. Guo, and P.B. Watkins Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression J. Clin. Invest. 99 1997 2545 2553
27. O.H. Lowry, N.J. Rosebrough, A.L. Farry, and R.J. Randall Protein measurement with folin-phenol reagent J. Biol. Chem. 193 1951 265 275
28. K.J. Netter, G.F. Kahl, and M.P. Magnussen Eine Method zur direkten Messung der O-Methylierung in Lebermikrosomen und ihre Anwendung auf Mikrosomenhemmwirkung von SKF-525-A Naunyn. Schmidberg's Arch. Exp. Pathol. Pharmakol. 238 1960 292 300
29. F. Nosten, and P. Brasseur Combination therapy for malaria: the way forward? Drugs 62 2002 1315 1329
30. T. Omura, and R. Sato The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its haemoprotein nature J. Biol. Chem. 235 1964 2370 2378
31. J. Pellegrino, C.A. Oliveira, J. Faria, and A.S. Cunha New approach to the screening of drugs in experimental S. mansoni in mice Am. J. Trop. Med. Hyg. 11 1962 201 215
32. S. Reitman, and S. Frankel A colourimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminases Am. J. Clin. Pathol. 28 1957 56 63
33. S.A. Sheweita, S.A. Mangoura, and A.G. El-Shemi Different levels of S. mansoni infection induced changes in drug-metabolising enzymes J. Helminthol. 72 1998 71 77
34. T. Shimada, H. Yamazaki, M. Mimura, Y. Inui, and F.P. Guengerich Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians J. Pharmacol. Exp. Ther. 270 1994 414 423
35. J. Utzinger, and J. Keiser Schistosomiasis and soil-transmitted helminthiasis: common drugs for treatment and control Expert. Opin. Pharmacother. 5 2004 263 285
36. J. Utzinger, S.H. Xiao, E.K. N'Goran, R. Bergquist, and M. Tanner The potential of artemether for the control of schistosomiasis Int. J. Parasitol. 31 2001 1549 1562
37. J. Utzinger, J. Chollet, Z.W. Tu, S.H. Xiao, and M. Tanner Comparative study of the effects of artemether and artesunate on juvenile and adult Schistosoma mansoni in experimentally infected mice Trans. R. Soc. Trop. Med. Hyg. 96 2002 318 323
38. M.A. van Agtmael, V. Gupta, T.H. van Der Wosten, J.P.B. Rutten, and C.J. van Boxtel Grapefruit juice increases the bioavailability of artemether Eur. J. Clin. Pharmacol. 55 1999 405 410
39. M.A. van Agtmael, V. Gupta, C.A. van der Graaf, and C.J. van Boxtel The effect of grapefruit juice on the time-dependent decline of artemether plasma levels in healthy subjects Clin. Pharmacol. Ther. 66 1999 408 414
40. E.J. Wang, C.N. Casciano, R.P. Clement, and W.W. Johnson Inhibition of P-glycoprotein transport function by grapefruit juice psoralen Pharm. Res. 18 2001 432 438
41. P.E. Weichselbaum An accurate and rapid method for determination of protein in small amounts of blood serum and plasma Am. J. Trop. Clin. Pathol. 16 1946 40
42. WHO, 2002. Prevention and control of schistosomiasis and soil-transmitted helminthiasis. First Report of the Joint WHO Expert Committees. WHO Technical Report Series No. 912, World Health Organization, Geneva.
43. S.H. Xiao, and B.A. Catto In vitro and in vivo studies of the effect of artemether on Schistosoma mansoni Antimicrob. Agents Chemother. 33 1989 1557 1562
44. S.H. Xiao, J.Q. You, Y.Q. Yang, and C.Z. Wang Experimental studies on early treatment of schistosomal infection with artemether Southeast Asian J. Trop. Med. Public Health 26 1995 306 318
45. S.H. Xiao, Y.Q. Yang, C.W. Zhang, and J.Q. You Microscopic observations on livers of rabbits and dogs infected with Schistosoma japonicum cercariae and early treatment with artemether or praziquantel Zhongguo Yoo Li Xue Bao 17 1996 167 170
46. S.H. Xiao, J. Chollet, N.A. Weiss, R.N. Bergquist, and M. Tanner Preventive effect of artemether in experimental animals infected with Schistosoma mansoni Parasitol. Int. 49 2000 19 24
47. S.H. Xiao, B.G. Shen, J. Chollet, J. Utzinger, and M. Tanner Tegumental changes in adult Schistosoma mansoni harbored in mice treated with artemether J. Parasitol. 86 2000 1125 1132
48. S.H. Xiao, M. Tanner, E.K. N'Goran, J. Utzinger, J. Chollet, R. Bergquist, M.G. Chen, and J. Zeng Recent investigations of artemether, a novel agent for the prevention of schistosomiasis japonica, mansoni and haematobia Acta Trop. 82 2002 175 181