Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds

Journal of Pharmacy and Pharmaceutical Sciences

Volumn 4, Issue 3, 2001, Pages 217-227

  Ho, Ping Chuen ^a   Saville, Dorothy J ^a   Wanwimolruk, Sompon ^b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APIGENIN; AURANTIIN; BERGAPTEN; CHRYSIN; COUMARIN; CYTOCHROME P450 3A4; DIMETHYL SULFOXIDE; FISETIN; FLAVANONE DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOID; FURAN; FUROCOUMARIN DERIVATIVE; GALANGIN; HESPERETIN; HESPERIDIN; HYDROQUININE; KAEMPFEROL; MORIN; MYRICETIN; NARINGENIN; NARIRUTIN; NEOHESPERIDIN; PHENOL; PRUNIN; QUERCETIN; QUININE; RHOIFOLIN; RUTOSIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ADULT; ARTICLE; CASE REPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG METABOLISM; DRUG POTENCY; DRUG SOLUBILITY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; FOOD DRUG INTERACTION; GRAPEFRUIT JUICE; HUMAN; HUMAN CELL; HYDROXYLATION; IC 50; INCUBATION TIME; LIVER MICROSOME; LIVER MICROSOME METABOLISM; MALE;

BEVERAGES; CITRUS; COUMARINS; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; FURANS; HUMANS; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; PLANT EXTRACTS;

EID: 0035734306     PISSN: 14821826     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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