Mechanism-based inactivation of hepatic ethoxyresorufin O-dealkylation activity by naturally occurring coumarins

Chemical Research in Toxicology

Volumn 9, Issue 4, 1996, Pages 729-736

  Cai, Yingna ^a   Baer Dubowska, Wanda ^a   Ashwood Smith, Mike J ^b   Ceska, Oluna ^b   Tachibana, Sanro ^b   DiGiovanni, John ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF VICTORIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLCHOLANTHRENE; ALPHA NAPHTHOFLAVONE; APOPROTEIN; COUMARIN DERIVATIVE; CYTOCHROME P450; ETHOXYRESORUFIN DEETHYLASE; HEME; ISOPIMPINELLIN; MONOCLONAL ANTIBODY; OSTRUTHOL; PENTOSALEN; PHENOBARBITAL; POLYCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DIET; DNA ADDUCT; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; FEMALE; LIVER MICROSOME; MOUSE; NONHUMAN; PROTEIN DNA INTERACTION;

ANIMALS; ANTICOAGULANTS; ANTICONVULSANTS; CARBON RADIOISOTOPES; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARINS; CYTOCHROME P-450 CYP1A1; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; FEMALE; HEME; HUMANS; HYPNOTICS AND SEDATIVES; METHYLCHOLANTHRENE; MICE; MICE, INBRED SENCAR; MICROSOMES, LIVER; PHENOBARBITAL; PLANT EXTRACTS; PSORALENS; RADIOLIGAND ASSAY;

ANIMALIA; MURINAE;

EID: 0029897471     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx950208b     Document Type: Article

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