메뉴 건너뛰기




Volumn 6, Issue 1, 2011, Pages

A novel modular antigen delivery system for immuno targeting of human 6-sulfo LacNAc-positive blood dendritic cells (slanDCs)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN M; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; TETANUS TOXIN; 6 SULFO LACNAC; 6-SULFO-LACNAC; AMINOSUGAR; ANTIGEN; MEMBRANE PROTEIN; P SELECTIN LIGAND PROTEIN; P-SELECTIN LIGAND PROTEIN; VACCINE;

EID: 79251603274     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016315     Document Type: Article
Times cited : (25)

References (39)
  • 1
    • 34249790004 scopus 로고    scopus 로고
    • Molecular mechanisms of antibody somatic hypermutation
    • Di Noia JM, Neuberger MS (2007) Molecular mechanisms of antibody somatic hypermutation. Annual Rev Biochem 76: 1-22.
    • (2007) Annual Rev Biochem , vol.76 , pp. 1-22
    • di Noia, J.M.1    Neuberger, M.S.2
  • 2
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • Rajewsky K (1996) Clonal selection and learning in the antibody system. Nature 381: 751-758.
    • (1996) Nature , vol.381 , pp. 751-758
    • Rajewsky, K.1
  • 3
    • 0032858194 scopus 로고    scopus 로고
    • Molecular processes that regulate class switching
    • Stavnezer J (2000) Molecular processes that regulate class switching. Curr Top Microbiol Immunol 245: 127-168.
    • (2000) Curr Top Microbiol Immunol , vol.245 , pp. 127-168
    • Stavnezer, J.1
  • 4
    • 0035404678 scopus 로고    scopus 로고
    • Linking class-switch recombination with somatic hypermutation
    • Kinoshita K, Honjo T (2001) Linking class-switch recombination with somatic hypermutation. Nat Rev Mol Cell Biol 2: 493-503.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 493-503
    • Kinoshita, K.1    Honjo, T.2
  • 5
    • 0036152242 scopus 로고    scopus 로고
    • Mechanism and control of class-switch recombination
    • Manis JP, Tian M, Alt FW (2002) Mechanism and control of class-switch recombination. Trends Immunol 23: 31-39.
    • (2002) Trends Immunol , vol.23 , pp. 31-39
    • Manis, J.P.1    Tian, M.2    Alt, F.W.3
  • 6
    • 0033603340 scopus 로고    scopus 로고
    • Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
    • Muramatsu M, Sankaranand VS, Anant S, Sugai M, Kinoshita K, et al. (1999) Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J Biol Chem 25: 18470-18476.
    • (1999) J Biol Chem , vol.25 , pp. 18470-18476
    • Muramatsu, M.1    Sankaranand, V.S.2    Anant, S.3    Sugai, M.4    Kinoshita, K.5
  • 7
    • 0037388165 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
    • Bransteitter R, Pham P, Scharff MD, Goodman MF (2002) Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc Natl Acad Sci U S A 100: 4102-4107.
    • (2002) Proc Natl Acad Sci U S A , vol.100 , pp. 4102-4107
    • Bransteitter, R.1    Pham, P.2    Scharff, M.D.3    Goodman, M.F.4
  • 8
    • 27144432842 scopus 로고    scopus 로고
    • Engineered antibody fragments and the rise of single domains
    • Holliger P, Hudson PJ (2005) Engineered antibody fragments and the rise of single domains. Nat Biotechnol 23: 1126-1136.
    • (2005) Nat Biotechnol , vol.23 , pp. 1126-1136
    • Holliger, P.1    Hudson, P.J.2
  • 9
    • 0031796797 scopus 로고    scopus 로고
    • A novel dendritic cell population in human blood: One-step immunomagnetic isolation by a specific mAb (M-DC8) and in vitro priming of cytotoxic T lymphocytes
    • Schäkel K, Mayer E, Federle C, Schmitz M, Riethmüller G, et al. (1998) A novel dendritic cell population in human blood: one-step immunomagnetic isolation by a specific mAb (M-DC8) and in vitro priming of cytotoxic T lymphocytes. Eur J Immunol 28: 4084-4093.
    • (1998) Eur J Immunol , vol.28 , pp. 4084-4093
    • Schäkel, K.1    Mayer, E.2    Federle, C.3    Schmitz, M.4    Riethmüller, G.5
  • 11
    • 0036754935 scopus 로고    scopus 로고
    • 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells
    • Schäkel K, Kannagi R, Kniep B, Goto Y, Mitsuoka C, et al. (2002) 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells. Immunity 17: 289-301.
    • (2002) Immunity , vol.17 , pp. 289-301
    • Schäkel, K.1    Kannagi, R.2    Kniep, B.3    Goto, Y.4    Mitsuoka, C.5
  • 12
    • 33745062776 scopus 로고    scopus 로고
    • Human 6-sulfo LacNAc-expressing dendritic cells are principal producers of early interleukin-12 and are controlled by erythrocytes
    • Schäkel K, von Kietzell M, Hänsel A, Ebling A, et al. (2006) Human 6-sulfo LacNAc-expressing dendritic cells are principal producers of early interleukin-12 and are controlled by erythrocytes. Immunity 24: 767-777.
    • (2006) Immunity , vol.24 , pp. 767-777
    • Schäkel, K.1    von Kietzell, M.2    Hänsel, A.3    Ebling, A.4
  • 13
    • 20144380950 scopus 로고    scopus 로고
    • Tumoricidal potential of native blood dendritic cells: Direct tumor cell killing and activation of NK cell-mediated cytotoxicity
    • Schmitz M, Zhao S, Deuse Y, Schäkel K, Wehner R, et al. (2005) Tumoricidal potential of native blood dendritic cells: direct tumor cell killing and activation of NK cell-mediated cytotoxicity. J Immunol 174: 4127-4134.
    • (2005) J Immunol , vol.174 , pp. 4127-4134
    • Schmitz, M.1    Zhao, S.2    Deuse, Y.3    Schäkel, K.4    Wehner, R.5
  • 14
    • 0024792810 scopus 로고
    • Identification of La ribonucleoproteins as a component of interchromatin granules
    • Carmo-Fonseca M, Pfeifer K, Schröder HC, Vaz MF, Fonseca JE, et al. (1989) Identification of La ribonucleoproteins as a component of interchromatin granules. Exp Cell Res 185: 73-85.
    • (1989) Exp Cell Res , vol.185 , pp. 73-85
    • Carmo-Fonseca, M.1    Pfeifer, K.2    Schröder, H.C.3    Vaz, M.F.4    Fonseca, J.E.5
  • 15
    • 0043198174 scopus 로고    scopus 로고
    • Dendritic cells and host resistance to infection
    • Moll H (2003) Dendritic cells and host resistance to infection. Cell Microbiol 5: 493-500.
    • (2003) Cell Microbiol , vol.5 , pp. 493-500
    • Moll, H.1
  • 16
    • 0033178828 scopus 로고    scopus 로고
    • The role of dendritic cells in the induction and regulation of immunity to microbial infection
    • Sousa CRE, Sher A, Kaye P (1999) The role of dendritic cells in the induction and regulation of immunity to microbial infection. Curr Opin Immunol 11: 392-399.
    • (1999) Curr Opin Immunol , vol.11 , pp. 392-399
    • Sousa, C.R.E.1    Sher, A.2    Kaye, P.3
  • 17
    • 13444301304 scopus 로고    scopus 로고
    • Regulation of antigen presentation and crosspresentation in the dendritic cell network: Facts, hypothesis, and immunological implications
    • Wilson NS, Villadangos JA (2005) Regulation of antigen presentation and crosspresentation in the dendritic cell network: facts, hypothesis, and immunological implications. Adv Immunol 86: 241-305.
    • (2005) Adv Immunol , vol.86 , pp. 241-305
    • Wilson, N.S.1    Villadangos, J.A.2
  • 18
    • 17144417748 scopus 로고    scopus 로고
    • Dendritic cells as therapeutic vaccines against cancer
    • Banchereau J, Palucka AK (2005) Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol 5: 296-306.
    • (2005) Nat Rev Immunol , vol.5 , pp. 296-306
    • Banchereau, J.1    Palucka, A.K.2
  • 19
    • 33847230184 scopus 로고    scopus 로고
    • Receptor-mediated delivery of antigens to dendritic cells: Anticancer applications
    • Proudfoot O, Apostolopoulos V, Pietersz GA (2007) Receptor-mediated delivery of antigens to dendritic cells: anticancer applications. Mol Pharm 4: 58-72.
    • (2007) Mol Pharm , vol.4 , pp. 58-72
    • Proudfoot, O.1    Apostolopoulos, V.2    Pietersz, G.A.3
  • 20
    • 0037122011 scopus 로고    scopus 로고
    • Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance
    • Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, et al. (2002) Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med 196: 1627-1638.
    • (2002) J Exp Med , vol.196 , pp. 1627-1638
    • Bonifaz, L.1    Bonnyay, D.2    Mahnke, K.3    Rivera, M.4    Nussenzweig, M.C.5
  • 21
    • 12144286596 scopus 로고    scopus 로고
    • In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination
    • Bonifaz LC, Bonnyay DP, Charalambous A, Darguste DI, Fujii S, et al. (2004) In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J Exp Med 199: 815-824.
    • (2004) J Exp Med , vol.199 , pp. 815-824
    • Bonifaz, L.C.1    Bonnyay, D.P.2    Charalambous, A.3    Darguste, D.I.4    Fujii, S.5
  • 23
    • 33845425072 scopus 로고    scopus 로고
    • Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin
    • Charalambous A, Oks M, Nchinda G, Yamazaki S, Steinman RM (2006) Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin. J Immunol 177: 8410-8421.
    • (2006) J Immunol , vol.177 , pp. 8410-8421
    • Charalambous, A.1    Oks, M.2    Nchinda, G.3    Yamazaki, S.4    Steinman, R.M.5
  • 24
    • 33846574833 scopus 로고    scopus 로고
    • DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes
    • Bozzacco L, Trumpfheller C, Siegal FP, Mehandru S, Markowitz M, et al. (2007) DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes. Proc Natl Acad Sci U S A 104: 1289-1294.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 1289-1294
    • Bozzacco, L.1    Trumpfheller, C.2    Siegal, F.P.3    Mehandru, S.4    Markowitz, M.5
  • 25
    • 38349052185 scopus 로고    scopus 로고
    • Broad T cell immunity to the LcrV virulence protein is induced by targeted delivery to DEC- 205/CD205-positive mouse dendritic cells
    • Do Y, Park CG, Kang YS, Park SH, Lynch RM, et al. (2008) Broad T cell immunity to the LcrV virulence protein is induced by targeted delivery to DEC- 205/CD205-positive mouse dendritic cells. Eur J Immunol 38: 20-29.
    • (2008) Eur J Immunol , vol.38 , pp. 20-29
    • Do, Y.1    Park, C.G.2    Kang, Y.S.3    Park, S.H.4    Lynch, R.M.5
  • 26
    • 51649112493 scopus 로고    scopus 로고
    • Targeting the nuclear antigen 1 of Epstein Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses
    • Gurer C, Strowig T, Brilot F, Pack M, Trumpfheller C, et al. (2008) Targeting the nuclear antigen 1 of Epstein Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Blood 112: 1231-1239.
    • (2008) Blood , vol.112 , pp. 1231-1239
    • Gurer, C.1    Strowig, T.2    Brilot, F.3    Pack, M.4    Trumpfheller, C.5
  • 27
    • 44049086242 scopus 로고    scopus 로고
    • Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice
    • Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, et al. (2008) Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice. Proc Natl Acad Sci U S A 105: 6374-6379.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 6374-6379
    • Mukhopadhaya, A.1    Hanafusa, T.2    Jarchum, I.3    Chen, Y.G.4    Iwai, Y.5
  • 28
    • 0034735552 scopus 로고    scopus 로고
    • The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments
    • Mahnke K, Guo M, Lee S, Sepulveda H, Swain SL, et al. (2000) The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J Cell Biol 151: 673-684.
    • (2000) J Cell Biol , vol.151 , pp. 673-684
    • Mahnke, K.1    Guo, M.2    Lee, S.3    Sepulveda, H.4    Swain, S.L.5
  • 29
    • 33644691658 scopus 로고    scopus 로고
    • On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes
    • Bruder D, Westendorf AM, Hansen W, Prettin S, Gruber AD, et al. (2005) On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes. Diabetes 54: 3395-3401.
    • (2005) Diabetes , vol.54 , pp. 3395-3401
    • Bruder, D.1    Westendorf, A.M.2    Hansen, W.3    Prettin, S.4    Gruber, A.D.5
  • 30
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, et al. (2001) Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 194: 769-779.
    • (2001) J Exp Med , vol.194 , pp. 769-779
    • Hawiger, D.1    Inaba, K.2    Dorsett, Y.3    Guo, M.4    Mahnke, K.5
  • 31
    • 2942523789 scopus 로고    scopus 로고
    • Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo
    • Hawiger D, Masilamani RF, Bettelli E, Kuchroo VK, Nussenzweig MC (2004) Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo. Immunity 20: 695-705.
    • (2004) Immunity , vol.20 , pp. 695-705
    • Hawiger, D.1    Masilamani, R.F.2    Bettelli, E.3    Kuchroo, V.K.4    Nussenzweig, M.C.5
  • 33
    • 77957699240 scopus 로고    scopus 로고
    • Targeting of DEC-205 on human dendritic cells results in efficient MHC class II-restricted antigen presentation
    • [Epub ahead of print]
    • Birkholz K, Schwenkert M, Kellner C, Gross S, Fey G, et al. (2010) Targeting of DEC-205 on human dendritic cells results in efficient MHC class II-restricted antigen presentation. Blood [Epub ahead of print].
    • (2010) Blood
    • Birkholz, K.1    Schwenkert, M.2    Kellner, C.3    Gross, S.4    Fey, G.5
  • 34
    • 67149098316 scopus 로고    scopus 로고
    • Neutrophils phagocytose activated platelets in vivo: A phosphatidylserine, P-selectin, and β2 integrin-dependent cell clearance program
    • Maugeri N, Rovere-Querini P, Evangelista V, Covino C, Capobianco A, et al. (2009) Neutrophils phagocytose activated platelets in vivo: a phosphatidylserine, P-selectin, and β2 integrin-dependent cell clearance program. Blood 21: 5254-5265.
    • (2009) Blood , vol.21 , pp. 5254-5265
    • Maugeri, N.1    Rovere-Querini, P.2    Evangelista, V.3    Covino, C.4    Capobianco, A.5
  • 35
    • 36349032254 scopus 로고    scopus 로고
    • Presence of anti-La autoantibody is associated with a lower risk of nephritis and seizures in lupus patients
    • Malik S, Bruner GR, Williams-Weese C, Feo L, Scofield RH, et al. (2007) Presence of anti-La autoantibody is associated with a lower risk of nephritis and seizures in lupus patients. Lupus 16: 863-866.
    • (2007) Lupus , vol.16 , pp. 863-866
    • Malik, S.1    Bruner, G.R.2    Williams-Weese, C.3    Feo, L.4    Scofield, R.H.5
  • 36
    • 0023154860 scopus 로고
    • Implications of anti-Ro/Sjögren's syndrome A antigen autoantibody in normal sera for autoimmunity
    • Gaither KK, Fox OF, Yamagata H, Mamula MJ, et al. (1987) Implications of anti-Ro/Sjögren's syndrome A antigen autoantibody in normal sera for autoimmunity. J Clin Invest 79: 841-846.
    • (1987) J Clin Invest , vol.79 , pp. 841-846
    • Gaither, K.K.1    Fox, O.F.2    Yamagata, H.3    Mamula, M.J.4
  • 37
    • 0033958471 scopus 로고    scopus 로고
    • Universal PCR amplification of mouse immunoglobulin gene variable regions: The design of degenerate primers and an assessment of the effect of DNA polymerase 3′ to 5′ exonuclease activity
    • Wang Z, Raifu M, Howard M, Smith L, Hansen D, et al. (2000) Universal PCR amplification of mouse immunoglobulin gene variable regions: the design of degenerate primers and an assessment of the effect of DNA polymerase 3′ to 5′ exonuclease activity. J Immunol Methods 13: 167-177.
    • (2000) J Immunol Methods , vol.13 , pp. 167-177
    • Wang, Z.1    Raifu, M.2    Howard, M.3    Smith, L.4    Hansen, D.5
  • 38
    • 34250839415 scopus 로고    scopus 로고
    • Targeting of tumor cells expressing the prostate stem cell antigen (PSCA) using genetically engineered T-cells
    • Morgenroth A, Cartellieri M, Schmitz M, Günes S, Weigle B, et al. (2007) Targeting of tumor cells expressing the prostate stem cell antigen (PSCA) using genetically engineered T-cells. Prostate 67: 1121-1131.
    • (2007) Prostate , vol.67 , pp. 1121-1131
    • Morgenroth, A.1    Cartellieri, M.2    Schmitz, M.3    Günes, S.4    Weigle, B.5
  • 39
    • 0345059081 scopus 로고    scopus 로고
    • A sensitive method for detecting proliferation of rare autoantigen-specific human T cells
    • Mannering SI, Morris JS, Jensen KP, Purcell AW, Honeyman MC, et al. (2003) A sensitive method for detecting proliferation of rare autoantigen-specific human T cells. J Immunol Methods 283: 173-183.
    • (2003) J Immunol Methods , vol.283 , pp. 173-183
    • Mannering, S.I.1    Morris, J.S.2    Jensen, K.P.3    Purcell, A.W.4    Honeyman, M.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.