-
2
-
-
68849093379
-
Mechanisms of immunosenescence
-
Caruso C., Buffa S., Candore G., Colonna-Romano G., Dunn-Walters D., Kipling D., Pawelec G. Mechanisms of immunosenescence. Immun. Ageing 2009, 6:10.
-
(2009)
Immun. Ageing
, vol.6
, pp. 10
-
-
Caruso, C.1
Buffa, S.2
Candore, G.3
Colonna-Romano, G.4
Dunn-Walters, D.5
Kipling, D.6
Pawelec, G.7
-
3
-
-
0036847971
-
Aging and developmental transitions in the B cell lineage
-
Johnson K.M., Owen K., Witte P.L. Aging and developmental transitions in the B cell lineage. Int. Immunol. 2002, 14:1313-1323.
-
(2002)
Int. Immunol.
, vol.14
, pp. 1313-1323
-
-
Johnson, K.M.1
Owen, K.2
Witte, P.L.3
-
4
-
-
4444320808
-
Ageing, autoimmunity and arthritis: senescence of the B cell compartment - implications for humoral immunity
-
Johnson S.A., Cambier J.C. Ageing, autoimmunity and arthritis: senescence of the B cell compartment - implications for humoral immunity. Arthritis Res. Ther. 2004, 6:131-139.
-
(2004)
Arthritis Res. Ther.
, vol.6
, pp. 131-139
-
-
Johnson, S.A.1
Cambier, J.C.2
-
5
-
-
34249775503
-
Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway
-
Agrawal A., Agrawal S., Cao J.N., Su H., Osann K., Gupta S. Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway. J. Immunol. 2007, 178:6912-6922.
-
(2007)
J. Immunol.
, vol.178
, pp. 6912-6922
-
-
Agrawal, A.1
Agrawal, S.2
Cao, J.N.3
Su, H.4
Osann, K.5
Gupta, S.6
-
6
-
-
38149134471
-
Biology of dendritic cells in aging
-
Agrawal A., Agrawal S., Tay J., Gupta S. Biology of dendritic cells in aging. J. Clin. Immunol. 2008, 28:14-20.
-
(2008)
J. Clin. Immunol.
, vol.28
, pp. 14-20
-
-
Agrawal, A.1
Agrawal, S.2
Tay, J.3
Gupta, S.4
-
7
-
-
47749124174
-
Innate immunity and aging
-
Gomez C.R., Nomellini V., Faunce D.E., Kovacs E.J. Innate immunity and aging. Exp. Gerontol. 2008, 43:718-728.
-
(2008)
Exp. Gerontol.
, vol.43
, pp. 718-728
-
-
Gomez, C.R.1
Nomellini, V.2
Faunce, D.E.3
Kovacs, E.J.4
-
8
-
-
69549133578
-
Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging
-
Agius E., Lacy K.E., Vukmanovic-Stejic M., Jagger A.L., Papageorgiou A.P., Hall S., Reed J.R., Curnow S.J., Fuentes-Duculan J., Buckley C.D., Salmon M., Taams L.S., Krueger J., Greenwood J., Klein N., Rustin M.H., Akbar A.N. Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging. J. Exp. Med. 2009, 206:1929-1940.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1929-1940
-
-
Agius, E.1
Lacy, K.E.2
Vukmanovic-Stejic, M.3
Jagger, A.L.4
Papageorgiou, A.P.5
Hall, S.6
Reed, J.R.7
Curnow, S.J.8
Fuentes-Duculan, J.9
Buckley, C.D.10
Salmon, M.11
Taams, L.S.12
Krueger, J.13
Greenwood, J.14
Klein, N.15
Rustin, M.H.16
Akbar, A.N.17
-
9
-
-
0031715650
-
Age-related modifications of the human alphabeta T cell repertoire due to different clonal expansions in the CD4+ and CD8+ subsets
-
Wack A., Cossarizza A., Heltai S., Barbieri D., D'Addato S., Fransceschi C., Dellabona P., Casorati G. Age-related modifications of the human alphabeta T cell repertoire due to different clonal expansions in the CD4+ and CD8+ subsets. Int. Immunol. 1998, 10:1281-1288.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1281-1288
-
-
Wack, A.1
Cossarizza, A.2
Heltai, S.3
Barbieri, D.4
D'Addato, S.5
Fransceschi, C.6
Dellabona, P.7
Casorati, G.8
-
10
-
-
0034194058
-
Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging
-
Fagnoni F.F., Vescovini R., Passeri G., Bologna G., Pedrazzoni M., Lavagetto G., Casti A., Franceschi C., Passeri M., Sansoni P. Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging. Blood 2000, 95:2860-2868.
-
(2000)
Blood
, vol.95
, pp. 2860-2868
-
-
Fagnoni, F.F.1
Vescovini, R.2
Passeri, G.3
Bologna, G.4
Pedrazzoni, M.5
Lavagetto, G.6
Casti, A.7
Franceschi, C.8
Passeri, M.9
Sansoni, P.10
-
11
-
-
1642462973
-
Characterization of naive, memory and effector CD8+ T cells: effect of age
-
Gupta S., Bi R., Su K., Yel L., Chiplunkar S., Gollapudi S. Characterization of naive, memory and effector CD8+ T cells: effect of age. Exp. Gerontol. 2004, 39:545-550.
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 545-550
-
-
Gupta, S.1
Bi, R.2
Su, K.3
Yel, L.4
Chiplunkar, S.5
Gollapudi, S.6
-
12
-
-
21044451726
-
The influence of age on T cell generation and TCR diversity
-
Naylor K., Li G., Vallejo A.N., Lee W.W., Koetz K., Bryl E., Witkowski J., Fulbright J., Weyand C.M., Goronzy J.J. The influence of age on T cell generation and TCR diversity. J. Immunol. 2005, 174:7446-7452.
-
(2005)
J. Immunol.
, vol.174
, pp. 7446-7452
-
-
Naylor, K.1
Li, G.2
Vallejo, A.N.3
Lee, W.W.4
Koetz, K.5
Bryl, E.6
Witkowski, J.7
Fulbright, J.8
Weyand, C.M.9
Goronzy, J.J.10
-
13
-
-
33745075615
-
A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis
-
Gupta S., Agrawal A., Agrawal S., Su H., Gollapudi S. A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis. Immun. Ageing 2006, 3:5.
-
(2006)
Immun. Ageing
, vol.3
, pp. 5
-
-
Gupta, S.1
Agrawal, A.2
Agrawal, S.3
Su, H.4
Gollapudi, S.5
-
14
-
-
40749132135
-
Homeostasis of the naive CD4+ T cell compartment during aging
-
Kilpatrick R.D., Rickabaugh T., Hultin L.E., Hultin P., Hausner M.A., Detels R., Phair J., Jamieson B.D. Homeostasis of the naive CD4+ T cell compartment during aging. J. Immunol. 2008, 180:1499-1507.
-
(2008)
J. Immunol.
, vol.180
, pp. 1499-1507
-
-
Kilpatrick, R.D.1
Rickabaugh, T.2
Hultin, L.E.3
Hultin, P.4
Hausner, M.A.5
Detels, R.6
Phair, J.7
Jamieson, B.D.8
-
15
-
-
77956621724
-
Gender specificity of altered human immune cytokine profiles in aging
-
Goetzl E.J., Huang M.C., Kon J., Patel K., Schwartz J.B., Fast K., Ferrucci L., Madara K., Taub D.D., Longo D.L. Gender specificity of altered human immune cytokine profiles in aging. FASEB J. 2010, 24:3580-3589.
-
(2010)
FASEB J.
, vol.24
, pp. 3580-3589
-
-
Goetzl, E.J.1
Huang, M.C.2
Kon, J.3
Patel, K.4
Schwartz, J.B.5
Fast, K.6
Ferrucci, L.7
Madara, K.8
Taub, D.D.9
Longo, D.L.10
-
16
-
-
20444497416
-
The number of human peripheral blood CD4+ CD25 high regulatory T cells increases with age
-
Gregg R., Smith C.M., Clark F.J., Dunnion D., Khan N., Chakraverty R., Nayak L., Moss P.A. The number of human peripheral blood CD4+ CD25 high regulatory T cells increases with age. Clin. Exp. Immunol. 2005, 140:540-546.
-
(2005)
Clin. Exp. Immunol.
, vol.140
, pp. 540-546
-
-
Gregg, R.1
Smith, C.M.2
Clark, F.J.3
Dunnion, D.4
Khan, N.5
Chakraverty, R.6
Nayak, L.7
Moss, P.A.8
-
17
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
Kim J.M., Rasmussen J.P., Rudensky A.Y. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 2007, 8:191-197.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
18
-
-
33846467889
-
Age-associated decline in effective immune synapse formation of CD4(+) T cells is reversed by vitamin E supplementation
-
Marko M.G., Ahmed T., Bunnell S.C., Wu D., Chung H., Huber B.T., Meydani S.N. Age-associated decline in effective immune synapse formation of CD4(+) T cells is reversed by vitamin E supplementation. J. Immunol. 2007, 178:1443-1449.
-
(2007)
J. Immunol.
, vol.178
, pp. 1443-1449
-
-
Marko, M.G.1
Ahmed, T.2
Bunnell, S.C.3
Wu, D.4
Chung, H.5
Huber, B.T.6
Meydani, S.N.7
-
19
-
-
49649117750
-
Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation
-
Lages C.S., Suffia I., Velilla P.A., Huang B., Warshaw G., Hildeman D.A., Belkaid Y., Chougnet C. Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation. J. Immunol. 2008, 181:1835-1848.
-
(2008)
J. Immunol.
, vol.181
, pp. 1835-1848
-
-
Lages, C.S.1
Suffia, I.2
Velilla, P.A.3
Huang, B.4
Warshaw, G.5
Hildeman, D.A.6
Belkaid, Y.7
Chougnet, C.8
-
20
-
-
77954442921
-
Human CD4-8- T cells are a distinctive immunoregulatory subset
-
Huang M.C., Patel K., Taub D.D., Longo D.L., Goetzl E.J. Human CD4-8- T cells are a distinctive immunoregulatory subset. FASEB J. 2010, 24:2558-2566.
-
(2010)
FASEB J.
, vol.24
, pp. 2558-2566
-
-
Huang, M.C.1
Patel, K.2
Taub, D.D.3
Longo, D.L.4
Goetzl, E.J.5
-
21
-
-
0029968318
-
Shortened telomeres in clonally expanded CD28-CD8+ T cells imply a replicative history that is distinct from their CD28+CD8+ counterparts
-
Monteiro J., Batliwalla F., Ostrer H., Gregersen P.K. Shortened telomeres in clonally expanded CD28-CD8+ T cells imply a replicative history that is distinct from their CD28+CD8+ counterparts. J. Immunol. 1996, 156:3587-3590.
-
(1996)
J. Immunol.
, vol.156
, pp. 3587-3590
-
-
Monteiro, J.1
Batliwalla, F.2
Ostrer, H.3
Gregersen, P.K.4
-
22
-
-
20344373118
-
The role of CD8+ T-cell replicative senescence in human aging
-
Effros R.B., Dagarag M., Spaulding C., Man J. The role of CD8+ T-cell replicative senescence in human aging. Immunol. Rev. 2005, 205:147-157.
-
(2005)
Immunol. Rev.
, vol.205
, pp. 147-157
-
-
Effros, R.B.1
Dagarag, M.2
Spaulding, C.3
Man, J.4
-
23
-
-
29744468405
-
TNF-alpha-induced apoptosis in human naive and memory CD8+ T cells in aged humans
-
Gupta S., Gollapudi S. TNF-alpha-induced apoptosis in human naive and memory CD8+ T cells in aged humans. Exp. Gerontol. 2006, 41:69-77.
-
(2006)
Exp. Gerontol.
, vol.41
, pp. 69-77
-
-
Gupta, S.1
Gollapudi, S.2
-
24
-
-
0029925555
-
Changes in lymphocyte subsets, interleukin 2, and soluble interleukin 2 receptor in old and very old age
-
Rea I.M., Stewart M., Campbell P., Alexander H.D., Crockard A.D., Morris T.C. Changes in lymphocyte subsets, interleukin 2, and soluble interleukin 2 receptor in old and very old age. Gerontology 1996, 42:69-78.
-
(1996)
Gerontology
, vol.42
, pp. 69-78
-
-
Rea, I.M.1
Stewart, M.2
Campbell, P.3
Alexander, H.D.4
Crockard, A.D.5
Morris, T.C.6
-
25
-
-
0029925346
-
Cytokine production pathway in the elderly
-
Caruso C., Candore G., Cigna D., DiLorenzo G., Sireci G., Dieli F., Salerno A. Cytokine production pathway in the elderly. Immunol. Res. 1996, 15:84-90.
-
(1996)
Immunol. Res.
, vol.15
, pp. 84-90
-
-
Caruso, C.1
Candore, G.2
Cigna, D.3
DiLorenzo, G.4
Sireci, G.5
Dieli, F.6
Salerno, A.7
-
26
-
-
0029742896
-
Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity
-
Corral L.G., Muller G.W., Moreira A.L., Chen Y., Wu M., Stirling D., Kaplan G. Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity. Mol. Med. 1996, 2:506-515.
-
(1996)
Mol. Med.
, vol.2
, pp. 506-515
-
-
Corral, L.G.1
Muller, G.W.2
Moreira, A.L.3
Chen, Y.4
Wu, M.5
Stirling, D.6
Kaplan, G.7
-
27
-
-
0033168605
-
Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
-
Corral L.G., Haslett P.A., Muller G.W., Chen R., Wong L.M., Ocampo C.J., Patterson R.T., Stirling D.I., Kaplan G. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J. Immunol. 1999, 163:380-386.
-
(1999)
J. Immunol.
, vol.163
, pp. 380-386
-
-
Corral, L.G.1
Haslett, P.A.2
Muller, G.W.3
Chen, R.4
Wong, L.M.5
Ocampo, C.J.6
Patterson, R.T.7
Stirling, D.I.8
Kaplan, G.9
-
28
-
-
19944430437
-
Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application
-
Hayashi T., Hideshima T., Akiyama M., Podar K., Yasui H., Raje N., Kumar S., Chauhan D., Treon S.P., Richardson P., Anderson K.C. Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application. Br. J. Haematol. 2005, 128:192-203.
-
(2005)
Br. J. Haematol.
, vol.128
, pp. 192-203
-
-
Hayashi, T.1
Hideshima, T.2
Akiyama, M.3
Podar, K.4
Yasui, H.5
Raje, N.6
Kumar, S.7
Chauhan, D.8
Treon, S.P.9
Richardson, P.10
Anderson, K.C.11
-
29
-
-
36849024949
-
Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo
-
Reddy N., Hernandez-Ilizaliturri F.J., Deeb G., Roth M., Vaughn M., Knight J., Wallace P., Czuczman M.S. Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo. Br. J. Haematol. 2008, 140:36-45.
-
(2008)
Br. J. Haematol.
, vol.140
, pp. 36-45
-
-
Reddy, N.1
Hernandez-Ilizaliturri, F.J.2
Deeb, G.3
Roth, M.4
Vaughn, M.5
Knight, J.6
Wallace, P.7
Czuczman, M.S.8
-
30
-
-
0038476461
-
Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs
-
Schafer P.H., Gandhi A.K., Loveland M.A., Chen R.S., Man H.W., Schnetkamp P.P., Wolbring G., Govinda S., Corral L.G., Payvandi F., Muller G.W., Stirling D.I. Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs. J. Pharmacol. Exp. Ther. 2003, 305:1222-1232.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 1222-1232
-
-
Schafer, P.H.1
Gandhi, A.K.2
Loveland, M.A.3
Chen, R.S.4
Man, H.W.5
Schnetkamp, P.P.6
Wolbring, G.7
Govinda, S.8
Corral, L.G.9
Payvandi, F.10
Muller, G.W.11
Stirling, D.I.12
-
31
-
-
27144458424
-
Immunomodulatory drugs (IMiDs) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kappaB, OCT-1, or NF-AT
-
Payvandi F., Wu L., Naziruddin S.D., Haley M., Parton A., Schafer P.H., Chen R.S., Muller G.W., Hughes C.C., Stirling D.I. Immunomodulatory drugs (IMiDs) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kappaB, OCT-1, or NF-AT. J. Interferon Cytokine Res. 2005, 25:604-616.
-
(2005)
J. Interferon Cytokine Res.
, vol.25
, pp. 604-616
-
-
Payvandi, F.1
Wu, L.2
Naziruddin, S.D.3
Haley, M.4
Parton, A.5
Schafer, P.H.6
Chen, R.S.7
Muller, G.W.8
Hughes, C.C.9
Stirling, D.I.10
-
32
-
-
67349107194
-
The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells
-
Galustian C., Meyer B., Labarthe M.C., Dredge K., Klaschka D., Henry J., Todryk S., Chen R., Muller G., Stirling D., Schafer P., Bartlett J.B., Dalgleish A.G. The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells. Cancer Immunol. Immunother. 2009, 58:1033-1045.
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 1033-1045
-
-
Galustian, C.1
Meyer, B.2
Labarthe, M.C.3
Dredge, K.4
Klaschka, D.5
Henry, J.6
Todryk, S.7
Chen, R.8
Muller, G.9
Stirling, D.10
Schafer, P.11
Bartlett, J.B.12
Dalgleish, A.G.13
-
33
-
-
67651111993
-
Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases
-
Xu Y., Li J., Ferguson G.D., Mercurio F., Khambatta G., Morrison L., Lopez-Girona A., Corral L.G., Webb D.R., Bennett B.L., Xie W. Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases. Blood 2009, 114:338-345.
-
(2009)
Blood
, vol.114
, pp. 338-345
-
-
Xu, Y.1
Li, J.2
Ferguson, G.D.3
Mercurio, F.4
Khambatta, G.5
Morrison, L.6
Lopez-Girona, A.7
Corral, L.G.8
Webb, D.R.9
Bennett, B.L.10
Xie, W.11
-
34
-
-
10744231369
-
Immunomodulatory drug costimulates T cells via the B7-CD28 pathway
-
LeBlanc R., Hideshima T., Catley L.P., Shringarpure R., Burger R., Mitsiades N., Mitsiades C., Cheema P., Chauhan D., Richardson P.G., Anderson K.C., Munshi N.C. Immunomodulatory drug costimulates T cells via the B7-CD28 pathway. Blood 2004, 103:1787-1790.
-
(2004)
Blood
, vol.103
, pp. 1787-1790
-
-
LeBlanc, R.1
Hideshima, T.2
Catley, L.P.3
Shringarpure, R.4
Burger, R.5
Mitsiades, N.6
Mitsiades, C.7
Cheema, P.8
Chauhan, D.9
Richardson, P.G.10
Anderson, K.C.11
Munshi, N.C.12
-
35
-
-
13544270248
-
Immunological effects of transgenic constitutive expression of the type 1 sphingosine 1-phosphate receptor by mouse lymphocytes
-
Graler M.H., Huang M.C., Watson S., Goetzl E.J. Immunological effects of transgenic constitutive expression of the type 1 sphingosine 1-phosphate receptor by mouse lymphocytes. J. Immunol. 2005, 174:1997-2003.
-
(2005)
J. Immunol.
, vol.174
, pp. 1997-2003
-
-
Graler, M.H.1
Huang, M.C.2
Watson, S.3
Goetzl, E.J.4
-
36
-
-
0242691672
-
Thiothalidomides: novel isosteric analogues of thalidomide with enhanced TNF-alpha inhibitory activity
-
Zhu X., Giordano T., Yu Q.S., Holloway H.W., Perry T.A., Lahiri D.K., Brossi A., Greig N.H. Thiothalidomides: novel isosteric analogues of thalidomide with enhanced TNF-alpha inhibitory activity. J. Med. Chem. 2003, 46:5222-5229.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 5222-5229
-
-
Zhu, X.1
Giordano, T.2
Yu, Q.S.3
Holloway, H.W.4
Perry, T.A.5
Lahiri, D.K.6
Brossi, A.7
Greig, N.H.8
-
37
-
-
0032100486
-
Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset
-
Haslett P.A., Corral L.G., Albert M., Kaplan G. Thalidomide costimulates primary human T lymphocytes, preferentially inducing proliferation, cytokine production, and cytotoxic responses in the CD8+ subset. J. Exp. Med. 1998, 187:1885-1892.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1885-1892
-
-
Haslett, P.A.1
Corral, L.G.2
Albert, M.3
Kaplan, G.4
-
38
-
-
2042507729
-
Determination of CC-5013, an analogue of thalidomide, in human plasma by liquid chromatography-mass spectrometry
-
Tohnya T.M., Hwang K., Lepper E.R., Fine H.A., Dahut W.L., Venitz J., Sparreboom A., Figg W.D. Determination of CC-5013, an analogue of thalidomide, in human plasma by liquid chromatography-mass spectrometry. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 2004, 811:135-141.
-
(2004)
J. Chromatogr. B Anal. Technol. Biomed. Life Sci.
, vol.811
, pp. 135-141
-
-
Tohnya, T.M.1
Hwang, K.2
Lepper, E.R.3
Fine, H.A.4
Dahut, W.L.5
Venitz, J.6
Sparreboom, A.7
Figg, W.D.8
-
39
-
-
67049171301
-
Phase I study of oral lenalidomide in patients with refractory metastatic cancer
-
Dahut W.L., Aragon-Ching J.B., Woo S., Tohnya T.M., Gulley J.L., Arlen P.M., Wright J.J., Ventiz J., Figg W.D. Phase I study of oral lenalidomide in patients with refractory metastatic cancer. J. Clin. Pharmacol. 2009, 49:650-660.
-
(2009)
J. Clin. Pharmacol.
, vol.49
, pp. 650-660
-
-
Dahut, W.L.1
Aragon-Ching, J.B.2
Woo, S.3
Tohnya, T.M.4
Gulley, J.L.5
Arlen, P.M.6
Wright, J.J.7
Ventiz, J.8
Figg, W.D.9
-
40
-
-
0033523712
-
Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice
-
Haynes L., Linton P.J., Eaton S.M., Tonkonogy S.L., Swain S.L. Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice. J. Exp. Med. 1999, 190:1013-1024.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1013-1024
-
-
Haynes, L.1
Linton, P.J.2
Eaton, S.M.3
Tonkonogy, S.L.4
Swain, S.L.5
-
41
-
-
77953638950
-
-
Distinct roles for IL-2 and IL-15 in the differentiation and survival of CD8+ effector and memory T cells. J. Immunol.
-
D.M. Mitchell, E.V. Ravkov, M.A. Williams, Distinct roles for IL-2 and IL-15 in the differentiation and survival of CD8+ effector and memory T cells. J. Immunol. 184 (2010) 6719-6730.
-
(2010)
, vol.184
, pp. 6719-6730
-
-
Mitchell, D.M.1
Ravkov, E.V.2
Williams, M.A.3
-
42
-
-
0019434273
-
Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans
-
Gillis S., Kozak R., Durante M., Weksler M.E. Immunological studies of aging. Decreased production of and response to T cell growth factor by lymphocytes from aged humans. J. Clin. Invest. 1981, 67:937-942.
-
(1981)
J. Clin. Invest.
, vol.67
, pp. 937-942
-
-
Gillis, S.1
Kozak, R.2
Durante, M.3
Weksler, M.E.4
-
43
-
-
23044433753
-
Homeostasis and the age-associated defect of CD4 T cells
-
Swain S., Clise-Dwyer K., Haynes L. Homeostasis and the age-associated defect of CD4 T cells. Semin. Immunol. 2005, 17:370-377.
-
(2005)
Semin. Immunol.
, vol.17
, pp. 370-377
-
-
Swain, S.1
Clise-Dwyer, K.2
Haynes, L.3
-
44
-
-
1642321982
-
IL-2, regulatory T cells, and tolerance
-
Nelson B.H. IL-2, regulatory T cells, and tolerance. J. Immunol. 2004, 172:3983-3988.
-
(2004)
J. Immunol.
, vol.172
, pp. 3983-3988
-
-
Nelson, B.H.1
-
46
-
-
0028813378
-
Apoptosis in an interleukin-2-dependent cytotoxic T lymphocyte cell line is associated with intracellular acidification. Role of the Na(+)/H(+)-antiport
-
Li J., Eastman A. Apoptosis in an interleukin-2-dependent cytotoxic T lymphocyte cell line is associated with intracellular acidification. Role of the Na(+)/H(+)-antiport. J. Biol. Chem. 1995, 270:3203-3211.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3203-3211
-
-
Li, J.1
Eastman, A.2
-
47
-
-
0038383027
-
Transcriptional program of apoptosis induction following interleukin 2 deprivation: identification of RC3, a calcium/calmodulin binding protein, as a novel proapoptotic factor
-
Devireddy L.R., Green M.R. Transcriptional program of apoptosis induction following interleukin 2 deprivation: identification of RC3, a calcium/calmodulin binding protein, as a novel proapoptotic factor. Mol. Cell. Biol. 2003, 23:4532-4541.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4532-4541
-
-
Devireddy, L.R.1
Green, M.R.2
-
48
-
-
13044311376
-
Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: a phase I/II clinical trial
-
Nussenblatt R.B., Fortin E., Schiffman R., Rizzo L., Smith J., Van Veldhuisen P., Sran P., Yaffe A., Goldman C.K., Waldmann T.A., Whitcup S.M. Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: a phase I/II clinical trial. Proc. Natl Acad. Sci. USA 1999, 96:7462-7466.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 7462-7466
-
-
Nussenblatt, R.B.1
Fortin, E.2
Schiffman, R.3
Rizzo, L.4
Smith, J.5
Van Veldhuisen, P.6
Sran, P.7
Yaffe, A.8
Goldman, C.K.9
Waldmann, T.A.10
Whitcup, S.M.11
-
49
-
-
2942537826
-
Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta
-
Bielekova B., Richert N., Howard T., Blevins G., Markovic-Plese S., McCartin J., Frank J.A., Wurfel J., Ohayon J., Waldmann T.A., McFarland H.F., Martin R. Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta. Proc. Natl Acad. Sci. USA 2004, 101:8705-8708.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 8705-8708
-
-
Bielekova, B.1
Richert, N.2
Howard, T.3
Blevins, G.4
Markovic-Plese, S.5
McCartin, J.6
Frank, J.A.7
Wurfel, J.8
Ohayon, J.9
Waldmann, T.A.10
McFarland, H.F.11
Martin, R.12
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