Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer

Biomaterials

Volumn 32, Issue 10, 2011, Pages 2614-2624

  Griesenbach, Uta ^a   Vicente, Catarina C ^a   Roberts, Megan J ^a   Meng, Cuixiang ^a   Soussi, Samia ^a   Xenariou, Stefania ^a   Tennant, Peter ^b   Baker, Alison ^b   Baker, Eilidh ^b   Gordon, Catherine ^b   Vrettou, Christina ^b   McCormick, Dominique ^c   Coles, Rebecca ^c   Green, Anne Marie ^c   Lawton, Anna E ^c   Sumner Jones, Stephanie G ^c   Cheng, Seng H ^d   Scheule, Ronald K ^d   Hyde, Stephen C ^c   Gill, Deborah R ^c   Collie, David D ^b   McLachlan, Gerry ^b   Alton, Eric W F W ^a   more..

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d GENZYME CORPORATION   (United States)

Author keywords

Epithelium; Gene transfer; Lipid; Lung

Indexed keywords

AIR LIQUID INTERFACES; CATIONIC LIPIDS; CLINICAL TRIAL; CLINICAL USE; CYSTIC FIBROSIS; EPITHELIUM; EX-VIVO; FIREFLY LUCIFERASE; GENE TRANSFECTION; HUMAN AIRWAY; IN-VIVO; LUNG; NEBULISATION; NONVIRAL; PRE-CLINICAL; PROMOTER ACTIVITIES; RECOMBINANT PROTEIN; REPORTER GENE; TRANSFER AGENTS;

BIOLOGICAL ORGANS; CELL CULTURE; GENE THERAPY; GENE TRANSFER; LIQUIDS; PHASE INTERFACES;

GENE EXPRESSION;

DRUG CARRIER; GL67A; LUCIFERASE; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; COPEPOD; DRUG BLOOD LEVEL; EX VIVO GENE TRANSFER; GAUSSIA PRINCEPS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO GENE TRANSFER; LUNG LAVAGE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; REPORTER GENE; RESPIRATORY EPITHELIUM; SHEEP;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; ELECTRICITY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENES, REPORTER; HEK293 CELLS; HUMANS; LIPIDS; LUCIFERASES; LUNG; MICE; POLYETHYLENEIMINE; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SHEEP; TIME FACTORS; TRANSFECTION; VIRUSES; WHOLE BODY IMAGING;

ANIMALIA; GAUSSIA PRINCEPS (T. SCOTT, 1894); OVIS; OVIS ARIES;

EID: 79251595357     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.12.001     Document Type: Article

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