Arabidopsis ETA2, an apparent ortholog of the human cullin-interacting protein CAND1, is required for auxin responses mediated by the SCF TIR1 ubiquitin ligase

Plant Cell

Volumn 16, Issue 7, 2004, Pages 1883-1897

  Chuang, Huey Wen ^a   Zhang, Wenjing ^a   Gray, William M ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; GENETIC ENGINEERING; HORMONES; ORGANIC ACIDS; PROTEINS;

MOLECULAR ANALYSIS; MUTATION;

PLANT CELL CULTURE;

ARABIDOPSIS; ARABIDOPSIS THALIANA; EMBRYOPHYTA;

EID: 3142702185     PISSN: 10404651     EISSN: None     Source Type: Journal    
DOI: 10.1105/tpc.021923     Document Type: Article

References (49)

1. Alonso, J.M., et al. (2003). Genome-wide insertional mutagenesis of Arabidopsis thaliana. Science 301, 653-657.
2. Cope, G.A., and Deshaies, R.J. (2003). COP9 signalosome: A multifunctional regulator of SCF and other cullin-based ubiquitin ligases. Cell 114, 663-671.
3. Cope, G.A., Suh, G.S., Aravind, L., Schwarz, S.E., Zipursky, S.L., Koonin, E.V., and Deshaies, R.J. (2002). Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298, 608-611.
4. del Pozo, J.C., Dharmasiri, S., Hellmann, H., Walker, L., Gray, W.M., and Estelle, M. (2002). AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis cullin AtCUL1 is required for auxin response. Plant Cell 14, 421-433.
5. del Pozo, J.C., and Estelle, M. (1999). The Arabidopsis cullin AtCUL1 is modified by the ubiquitin-related protein RUB1. Proc. Natl. Acad. Sci. USA 96, 15342-15347.
6. Dharmasiri, W., Dharmasiri, S., Jones, A.M., and Estelle, M. (2003a). Auxin action in a cell-free system. Curr. Biol. 13, 1418-1422.
7. Dharmasiri, S., Dharmasiri, N., Hellmann, H., and Estelle, M. (2003b). The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis. EMBO J. 22, 1762-1770.
8. Doronkin, S., Djagaeva, I., and Beckendorf, S.K. (2003). The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis. Dev. Cell 4, 699-710.
9. Feng, S., Ma, L., Wang, X., Xie, D., Dinesh-Kumar, S.P., Wei, N., and Deng, X.W. (2003). The COP9 signalosome interacts physically with SCF COU and modulates jasmonate responses. Plant Cell 15, 1083-1094.
10. Feng, S., Shen, Y., Sullivan, J.A., Rubio, V., Xiong, Y., Sun, T.-p., and Deng, X.W. (2004). Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein degradation. Plant Cell 16, 1870-1882.
11. Gagne, J.M., Downes, B.P., Shiu, S.H., Durski, A.M., and Vierstra, R.D. (2002). The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis. Proc. Natl. Acad. Sci. USA 99, 11519-11524.
12. Galan, J.M., and Peter, M. (1999). Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism. Proc. Natl. Acad. Sci. USA 96, 9124-9129.
13. Gray, W.M., del Pozo, J.C., Walker, L., Hobbie, L., Risseeuw, E., Banks, T., Crosby, W.L., Yang, M., Ma, H., and Estelle, M. (1999). Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana. Genes Dev. 13, 1678-1691.
14. Gray, W.M., and Estelle, I. (2000). Function of the ubiquitin-proteasome pathway in auxin response. Trends Biochem. Sci. 25, 133-138.
15. Gray, W.M., Hellmann, H., Dharmasiri, S., and Estelle, M. (2002). Role of the Arabidopsis RING-H2 protein RBX1 in RUB modification and SCF function. Plant Cell 14, 2137-2144.
16. Gray, W.M., Kepinski, S., Rouse, D., Leyser, O., and Estelle, M. (2001). Auxin regulates SCF(TIR1)-dependent degradation of AUX/IAA proteins. Nature 414, 271-276.
17. Gray, W.M., Muskett, P.R., Chuang, H.W., and Parker, J.E. (2003). Arabidopsis SGT1b is required for SCF(TIR1)-mediated auxin response. Plant Cell 15, 1310-1319.
18. Hellmann, H., Hobbie, L., Chapman, A., Dharmasiri, S., Dharmasiri, N., del Pozo, C., Reinhardt, D., and Estelle, M. (2003). Arabidopsis AXR6 encodes CUL1 implicating SCF E3 ligases in auxin regulation of embryogenesis. EMBO J. 22, 3314-3325.
19. Hwang, J.W., Min, K.W., Tamura, T.A., and Yoon, J.B. (2003). TIP120A associates with unneddylated cullin 1 and regulates its neddylation. FEBS Lett. 541, 102-108.
20. Jander, G., Morris, S.R., Rounsley, S.D., Bush, D.F., Levin, I.M., and Last, R.L. (2002). Arabidopsis map-based cloning in the post-genome era. Plant Physiol. 129, 440-450.
21. Kawakami, T., Chiba, T., Susuki, T., Iwai, K., Yamanaka, K., Minato, N., Suzuki, H., Shimbara, N., Hidaka, Y., Osaka, F., Omata, M., and Tanaka, K. (2001). NEDD8 recruits E2-ubiquitin to SCF E3 ligase. EMBO J. 20, 4003-4012.
22. Lammer, D., Mathias, M., Laplaza, J.M., Jiang, W., Liu, Y., Callis, J., Goebl, M., and Estelle, M. (1998). Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev. 14, 914-926.
23. Lincoln, C., Britton, J.H., and Estelle, M. (1990). Growth and development of the axr1 mutants of Arabidopsis. Plant Cell 2, 1071-1080.
24. Liu, J., Furukawa, M., Matsumoto, T., and Xiong, Y. (2002). NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases. Mol. Cell 10, 1511-1518.
25. Lyapina, S., Cope, G., Shevchenko, A., Serino, G., Tsuge, T., Zhou, C., Wolf, D.A., Wei, N., and Deshaies, R.J. (2001). Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science 292, 1382-1385.
26. Min, K.W., Hwang, J.W., Lea, J.S., Park, Y., Tamura, T.A., and Yoon, J.B. (2003). TIP120A associates with cullins and modulates ubiquitin ligase activity. J. Biol. Chem. 278, 15905-15910.
27. Nagpal, P., Walker, L.M., Young, J.C., Sonawala, A., Timpte, C., Estelle, M., and Reed, J.W. (2000). AXR2 encodes a member of the Aux/IAA protein family. Plant Physiol. 123, 563-574.
28. Oono, Y., Chen, Q.G., Overvoorde, P.J., Kohler, C., and Theologis, A. (1998). Age mutants of Arabidopsis exhibit altered auxin-regulated gene expression. Plant Cell 10, 1649-1662.
29. Oshikawa, K., Matsumoto, M., Yada, M., Kamura, T., Hatakeyama, S., and Nakayama, K.I. (2003). Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1. Biochem. Biophys. Res. Commun. 303, 1209-1216.
30. Quellet, F., Overvoorde, P.J., and Theologis, A. (2001). IAA17/AXR3: Biochemical insight into an auxin mutant phenotype. Plant Cell 13, 829-841.
31. Podust, V.M., Brownell, J.E., Gladysheva, T.B., Luo, R.S., Wang, C., Coggins, M.B., Pierce, J.W., Lightcap, E.S., and Chau, V. (2000). A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination. Proc. Natl. Acad. Sci. USA 97, 4579-4584.
32. Pringle, J.R., Preston, R.A., Adams, A.E., Stearns, T., Drubin, D.G., Haarer, B.K., and Jones, E.W. (1989). Fluorescence microscopy methods for yeast. Methods Cell Biol. 31, 357-435.
33. Ramos, J.A., Zenser, N., Leyser, O., and Callis, J. (2001). Rapid degradation of auxin/indoleacetic acid proteins requires conserved amino acids of domain Il and is proteasome dependent. Plant Cell 13, 2349-2360.
34. Read, M.A., Brownell, J.E., Gladysheva, T.B., Hottelet, M., Parent, L.A., Coggins, M.B., Pierce, J.W., Podust, V.M., Luo, R.S., Chau, V., and Palombella, V.J. (2000). Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha. Mol. Cell. Biol. 20, 2326-2333.
35. Rogg, L.E., Lasswell, J., and Bartel, B. (2001). A gain-of-function mutation in IAA28 suppresses lateral root development. Plant Cell 13, 465-480.
36. Rouse, D., Mackay, P., Stimberg, P., Estelle, M., and Leyser, O. (1998). Changes in auxin response from mutations in an AUX/IAA gene. Science 279, 1371-1373.
37. Ruegger, M., Dewey, E., Gray, W.M., Hobbie, L., Turner, J., and Estelle, M. (1998). The TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast grr1p. Genes Dev. 12, 198-207.
38. Schwechheimer, C., and Deng, X.W. (2000). The COP/DET/FUS proteins: Regulators of eukaryotic growth and development. Semin. Cell Dev. Biol. 11, 495-503.
39. Schwechheimer, C., Serino, G., Callis, J., Crosby, W.L., Lyapina, S., Deshaies, R.J., Gray, W.M., Estelle, M., and Deng, X.W. (2001). Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Science 292, 1379-1382.
40. Stomp, A.-M. (1991). Histochemical localization of β-glucuronidase. In GUS Protocols, S.R. Gallagher, ed (London: Academic Press), pp. 103-113.
41. Tao, Q., and Zhang, H.B. (1998). Cloning and stable maintenance of DNA fragments over 300 kb in Escherichia coli with conventional plasmid-based vectors. Nucleic Acids Res. 26, 4901-4909.
42. Tian, Q., and Reed, J.W. (1999). Control of auxin-regulated root development by the Arabidopsis thaliana SHY2/IAA3 gene. Development 126, 711-721.
43. Wirbelauer, C., Sutterluty, H., Blondel, M., Gstaiger, M., Peter, M., Reymond, F., and Krek, W. (2000). The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: Evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts. EMBO J. 19, 5362-5375.
44. Yang, X., Menon, S., Lykke-Andersen, K., Tsuge, T., Di, X., Wang, X., Rodriguez-Suarez, R.J., Zhang, H., and Wei, N. (2002). The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1. Curr. Biol. 12, 667-672.
45. Yogosawa, S., Makino, Y., Yoshida, T., Kishimoto, T., Muramatsu, M., and Tamura, T. (1996). Molecular cloning of a novel 120-kDa TBP-interacting protein. Biochem. Biophys. Res. Commun. 229, 612-617.
46. Zenser, N., Ellsmore, A., Leasure, C., and Callis, J. (2001). Auxin modulates the degradation rate of Aux/IAA proteins. Proc. Natl. Acad. Sci. USA 98, 11795-11800.
47. Zheng, J., Yang, X., Harrell, J.M., Ryzhikov, S., Shim, E.H., Lykke-Andersen, K., Wei, N., Sun, H., Kobayashi, R., and Zhang, H. (2002a). CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex. Mol. Cell 10, 1519-1526.
48. Zheng, N., et al. (2002b). Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature 416, 703-709.
49. Zhou, P., and Howley, P.M. (1998). Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases. Mol. Cell 2, 571-580.