Insight into glutamate excitotoxicity from synaptic zinc homeostasis

International Journal of Alzheimer's Disease

Volumn , Issue , 2011, Pages

  Takeda, Atsushi ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; ZINC;

ALZHEIMER DISEASE; CYTOSOL; EXCITOTOXICITY; HIPPOCAMPUS; HUMAN; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; ZINC METABOLISM;

EID: 79251579593     PISSN: None     EISSN: 20900252     Source Type: Journal    
DOI: 10.4061/2011/491597     Document Type: Review

References (112)

1. Vallee B. L., Falchuk K. H., The biochemical basis of zinc physiology Physiological Reviews 1993 73 1 79 118
2. Sandstead H. H., Frederickson C. J., Penland J. G., History of zinc as related to brain function Journal of Nutrition 2000 130 2 496S 502S
3. Burdette S. C., Lippard S. J., Meeting of the minds: metalloneurochemistry Proceedings of the National Academy of Sciences of the United States of America 2003 100 7 3605 3610
4. Markesbery W. R., Ehmann W. D., Alauddin M., Hossain T. I. M., Brain trace element concentrations in aging Neurobiology of Aging 1984 5 1 19 28
5. Weiss J. H., Sensi S. L., Koh J. Y., Zn 2+: a novel ionic mediator of neural injury in brain disease Trends in Pharmacological Sciences 2000 21 10 395 401
6. Hershey C. O., Hershey L. A., Varnes A., Cerebrospinal fluid trace element content in dementia: clinical, radiologic, and pathologic correlations Neurology 1983 33 10 1350 1353
7. Takeda A., Movement of zinc and its functional significance in the brain Brain Research Reviews 2000 34 3 137 148
8. Takeda A., Zinc homeostasis and functions of zinc in the brain BioMetals 2001 14 3-4 343 351
9. Takeda A., Akiyama T., Sawashita J., Okada S., Brain uptake of trace metals, zinc and manganese, in rats Brain Research 1994 640 1-2 341 344
10. Takeda A., Sawashita J., Okada S., Biological half-lives of zinc and manganese in rat brain Brain Research 1995 695 1 53 58
11. Capasso M., Jeng J. M., Malavolta M., Mocchegiani E., Sensi S. L., Zinc dyshomeostasis: a key modulator of neuronal injury Journal of Alzheimer's Disease 2005 8 2 93 108
12. Mocchegiani E., Bertoni-Freddari C., Marcellini F., Malavolta M., Brain, aging and neurodegeneration: role of zinc ion availability Progress in Neurobiology 2005 75 6 367 390
13. Bressler J. P., Olivi L., Cheong J. H., Kim Y., Maerten A., Bannon D., Metal transporters in intestine and brain: their involvement in metal-associated neurotoxicities Human and Experimental Toxicology 2007 26 3 221 229
14. Frederickson C. J., Neurobiology of zinc and zinc-containing neurons International review of neurobiology 1989 31 145 238
15. Frederickson C. J., Bush A. I., Synaptically released zinc: physiological functions and pathological effects BioMetals 2001 14 3-4 353 366
16. Frederickson C. J., Moncrieff D. W., Zinc-containing neurons Biological Signals 1994 3 3 127 139
17. Qian J., Noebels J. L., Visualization of transmitter release with zinc fluorescence detection at the mouse hippocampal mossy fibre synapse Journal of Physiology 2005 566 3 747 758
18. Frederickson C. J., Giblin L. J. III, Rengarajan B., Masalha R., Frederickson C. J., Zeng Y., Lopez E. V., Koh J. Y., Chorin U., Besser L., Hershfinkel M., Li Y., Thompson R. B., Krezel A., Synaptic release of zinc from brain slices: factors governing release, imaging, and accurate calculation of concentration Journal of Neuroscience Methods 2006 154 1-2 19 29
19. Valente T., Auladell C., Developmental expression of ZnT3 in mouse brain: correlation between the vesicular zinc transporter protein and chelatable vesicular zinc (CVZ) cells. Glial and neuronal CVZ cells interact Molecular and Cellular Neuroscience 2002 21 2 189 204
20. Valente T., Auladell C., Prez-Clausell J., Postnatal development of zinc-rich terminal fields in the brain of the rat Experimental Neurology 2002 174 2 215 229
21. Cole T. B., Martyanova A., Palmiter R. D., Removing zinc from synaptic vesicles does not impair spatial learning, memory, or sensorimotor functions in the mouse Brain Research 2001 891 1-2 253 265
22. Bird C. M., Burgess N., The hippocampus and memory: insights from spatial processing Nature Reviews Neuroscience 2008 9 3 182 194
23. Frederickson C. J., Danscher G., Zinc-containin neurons in hippocampus and related CNS structures Progress in Brain Research 1990 83 71 84
24. Sindreu C. B., Varoqui H., Erickson J. D., Prez-Clausell J., Boutons containing vesicular zinc define a subpopulation of synapses with low AMPAR content in rat hippocampus Cerebral Cortex 2003 13 8 823 829
25. Smart T. G., Xie X., Krishek B. J., Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc Progress in Neurobiology 1994 42 3 393 441
26. Besser L., Chorin E., Sekler I., Silverman W. F., Atkin S., Russell J. T., Hershfinkel M., Synaptically released zinc triggers metabotropic signaling via a zinc-sensing receptor in the hippocampus Journal of Neuroscience 2009 29 9 2890 2901
27. Takeda A., Tamano H., Insight into zinc signaling from dietary zinc deficiency Brain Research Reviews 2009 62 1 33 44
28. Takeda A., Tamano H., Zinc signaling through glucocorticoid and glutamate signaling in stressful circumstances Journal of Neuroscience Research 2010 88 14 3002 3010
29. Nakashima A. S., Dyck R. H., Zinc and cortical plasticity Brain Research Reviews 2009 59 2 347 373
30. Frederickson C. J., Koh J. Y., Bush A. I., The neurobiology of zinc in health and disease Nature Reviews Neuroscience 2005 6 6 449 462
31. Sensi S. L., Canzoniero L. M. T., Yu S. P., Ying H. S., Koh J. Y., Kerchner G. A., Choi D. W., Measurement of intracellular free zinc in living cortical neurons: routes of entry Journal of Neuroscience 1997 17 24 9554 9564
32. Frederickson C. J., Giblin L. J., Krezel A., McAdoo D. J., Muelle R. N., Zeng Y., Balaji R. V., Masalha R., Thompson R. B., Fierke C. A., Sarvey J. M., de Valdenebro M., Prough D. S., Zornow M. H., Concentrations of extracellular free zinc (pZn) in the central nervous system during simple anesthetization, ischemia and reperfusion Experimental Neurology 2006 198 2 285 293
33. Minami A., Sakurada N., Fuke S., Kikuchi K., Nagano T., Oku N., Takeda A., Inhibition of presynaptic activity by zinc released from mossy fiber terminals during tetanic stimulation Journal of Neuroscience Research 2006 83 1 167 176
34. Takeda A., Fuke S., Minami A., Oku N., Role of zinc influx via AMPA/kainate receptor activation in metabotropic glutamate receptor-mediated calcium release Journal of Neuroscience Research 2007 85 6 1310 1317
35. Takeda A., Fuke S., Tsutsumi W., Oku N., Negative modulation of presynaptic activity by zinc released from schaffer collaterals Journal of Neuroscience Research 2007 85 16 3666 3672
36. Sensi S. L., Ton-That D., Sullivan P. G., Jonas E. A., Gee K. R., Kaczmarek L. K., Weiss J. H., Modulation of mitochondrial function by endogenous Zn 2+ pools Proceedings of the National Academy of Sciences of the United States of America 2003 100 10 6157 6162
37. Maret W., Zinc coordination environments in proteins as redox sensors and signal transducers Antioxidants and Redox Signaling 2006 8 9-10 1419 1441
38. Krezel A., Hao Q., Maret W., The zinc/thiolate redox biochemistry of metallothionein and the control of zinc ion fluctuations in cell signaling Archives of Biochemistry and Biophysics 2007 463 2 188 200
39. Frazzini V., Rockabrand E., Mocchegiani E., Sensi S. L., Oxidative stress and brain aging: is zinc the link? Biogerontology 2006 7 5-6 307 314
40. Qin Y., Thomas D., Fontaine C. P., Colvin R. A., Mechanisms of Zn 2+ efflux in cultured cortical neurons Journal of Neurochemistry 2008 107 5 1304 1313
41. Hirano T., Kikuchi K., Urano Y., Nagano T., Improvement and biological applications of fluorescent probes for zinc, ZnAFs Journal of the American Chemical Society 2002 124 23 6555 6562
42. Jia Y., Jeng J. M., Sensi S. L., Weiss J. H., Zn 2+ currents are mediated by calcium-permeable AMPA/kainate channels in cultured murine hippocampal neurones Journal of Physiology 2002 543 1 35 48
43. Ando M., Oku N., Takeda A., Zinc-mediated attenuation of hippocampal mossy fiber long-term potentiation induced by forskolin Neurochemistry International 2010 57 5 608 614
44. Quinta-Ferreira M. E., Matias C. M., Hippocampal mossy fiber calcium transients are maintained during long-term potentiation and are inhibited by endogenous zinc Brain Research 2004 1004 1-2 52 60
45. Quinta-Ferreira M. E., Matias C. M., Tetanically released zinc inhibits hippocampal mossy fiber calcium, zinc and synaptic responses Brain Research 2005 1047 1 1 9
46. Bancila V., Nikonenko I., Dunant Y., Bloc A., Zinc inhibits glutamate release via activation of pre-synaptic KATP channels and reduces ischaemic damage in rat hippocampus Journal of Neurochemistry 2004 90 5 1243 1250
47. Cohen-Kfir E., Lee W., Eskandari S., Nelson N., Zinc inhibition of -aminobutyric acid transporter 4 (GAT4) a link between excitatory and inhibitory neurotransmission Proceedings of the National Academy of Sciences of the United States of America 2005 102 17 6154 6159
48. Lauri S. E., Bortolotto Z. A., Nistico R., Bleakman D., Ornstein P. L., Lodge D., Isaac J. T. R., Collingridge G. L., A role for Ca 2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus Neuron 2003 39 2 327 341
49. Rodrguez-Moreno A., Sihra T. S., Presynaptic kainate receptor facilitation of glutamate release involves protein kinase A in the rat hippocampus Journal of Physiology 2004 557 3 733 745
50. Koizumi S., Fujishita K., Inoue K., Regulation of cell-to-cell communication mediated by astrocytic ATP in the CNS Purinergic Signalling 2005 1 3 211 217
51. Domingues A. M. D. J., Taylor M., Fern R., Glia as transmitter sources and sensors in health and disease Neurochemistry International 2010 57 4 359 366
52. Takeda A., Minami A., Sakurada N., Nakajima S., Oku N., Response of hippocampal mossy fiber zinc to excessive glutamate release Neurochemistry International 2007 50 2 322 327
53. Koh J. Y., Suh S. W., Gwag B. J., He Y. Y., Hsu C. Y., Choi D. W., The role of zinc in selective neuronal death after transient global cerebral ischemia Science 1996 272 5264 1013 1016
54. Choi D. W., Koh J. Y., Zinc and brain injury Annual Review of Neuroscience 1998 21 347 375
55. Lee J. M., Zipfel G. J., Choi D. W., The changing landscape of ischaemic brain injury mechanisms Nature 1999 399 6738 A7 A14
56. Sensi S. L., Jeng J. M., Rethinking the excitotoxic ionic millieu: the emerging role of Zn 2+ in ischemic neuronal injury Current Molecular Medicine 2004 4 2 87 111
57. Noh K. M., Yokota H., Mashiko T., Castillo P. E., Zukin R. S., Bennett M. V. L., Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global schemia-induced death Proceedings of the National Academy of Sciences of the United States of America 2005 102 34 12230 12235
58. Suh S. W., Gum E. T., Hamby A. M., Chan P. H., Swanson R. A., Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase Journal of Clinical Investigation 2007 117 4 910 918
59. Hershfinkel M., Kandler K., Knoch M. E., Dagan-Rabin M., Aras M. A., Abramovitch-Dahan C., Sekler I., Aizenman E., Intracellular zinc inhibits KCC2 transporter activity Nature Neuroscience 2009 12 6 725 727
60. He K., Aizenman E., ERK signaling leads to mitochondrial dysfunction in extracellular zinc-induced neurotoxicity Journal of Neurochemistry 2010 114 2 452 461
61. Lee J. Y., Cole T. B., Palmiter R. D., Koh J. Y., Accumulation of zinc in degenerating hippocampal neurons of ZnT3-null mice after seizures: evidence against synaptic vesicle origin The Journal of Neuroscience 2000 20 11 RC79
62. Ct A., Chiasson M., Peralta M. R. III, Lafortune K., Pellegrini L., Tth K., Cell type-specific action of seizure-induced intracellular zinc accumulation in the rat hippocampus Journal of Physiology 2005 566 3 821 837
63. Lavoie N., Peralta M. R. III, Chiasson M., Lafortune K., Pellegrini L., Seress L., Tth K., Extracellular chelation of zinc does not affect hippocampal excitability and seizure-induced cell death in rats Journal of Physiology 2007 578 1 275 289
64. Takeda A., Tamano H., Itoh H., Oku N., Attenuation of abnormal glutamate release in zinc deficiency by zinc and Yokukansan Neurochemistry International 2008 53 6k8 230 235
65. Meldrum B. S., Glutamate as a neurotransmitter in the brain: review of physiology and pathology Journal of Nutrition 2000 130 4 1007S 1015S
66. Danbolt N. C., Glutamate uptake Progress in Neurobiology 2001 65 1 1 105
67. Dong X. X., Wang Y., Qin Z. H., Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases Acta Pharmacologica Sinica 2009 30 4 379 387
68. Choi D. W., Rothman S. M., The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death Annual Review of Neuroscience 1990 13 171 182
69. Lipton S. A., Rosenberg P. A., Mechanisms of disease: excitatory amino acids as a final common pathway for neurologic disorders New England Journal of Medicine 1994 330 9 613 622
70. Obrenovitch T. P., Urenjak J., Altered glutamatergic transmission in neurological disorders: from high extracellular glutamate to excessive synaptic efficacy Progress in Neurobiology 1997 51 1 39 87
71. Kawata M., Yuri K., Ozawa H., Nishi M., Ito T., Hu Z., Lu H., Yoshida M., Steroid hormones and their receptors in the brain Journal of Steroid Biochemistry and Molecular Biology 1998 65 1-6 273 280
72. Reagan L. P., McEwen B. S., Controversies surrounding glucocorticoid-mediated cell death in the hippocampus Journal of Chemical Neuroanatomy 1997 13 3 149 167
73. Takeda A., Tamano H., Kan F., Itoh H., Oku N., Anxiety-like behavior of young rats after 2-week zinc deprivation Behavioural Brain Research 2007 177 1 1 6
74. Takeda A., Hirate M., Tamano H., Nisibaba D., Oku N., Susceptibility to kainate-induced seizures under dietary zinc deficiency Journal of Neurochemistry 2003 85 6 1575 1580
75. Takeda A., Itoh H., Tamano H., Oku N., Responsiveness to kainate in young rats after 2-week zinc deprivation BioMetals 2006 19 5 565 572
76. Takeda A., Hirate M., Tamano H., Oku N., Release of glutamate and GABA in the hippocampus under zinc deficiency Journal of Neuroscience Research 2003 72 4 537 542
77. Takeda A., Itoh H., Nagayoshi A., Oku N., Abnormal Ca mobilization in hippocampal slices of epileptic animals fed a zinc-deficient diet Epilepsy Research 2009 83 1 73 80
78. Takeda A., Tamano H., Nagayoshi A., Yamada K., Oku N., Increase in hippocampal cell death after treatment with kainate in zinc deficiency Neurochemistry International 2005 47 8 539 544
79. Bush A. I., Pettingell W. H., Multhaup G., Paradis D. M., Vonsattel J. P., Gusella J. F., Beyreuther K., Masters C. L., Tanzi R. E., Rapid induction of Alzheimer A amyloid formation by zinc Science 1994 265 5177 1464 1467
80. Lee J. Y., Cole T. B., Palmiter R. D., Suh S. W., Koh J. Y., Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice Proceedings of the National Academy of Sciences of the United States of America 2002 99 11 7705 7710
81. Suh S. W., Jensen K. B., Jensen M. S., Silva D. S., Kesslak P. J., Danscher G., Frederickson C. J., Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains Brain Research 2000 852 2 274 278
82. Parameshwaran K., Dhanasekaran M., Suppiramaniam V., Amyloid beta peptides and glutamatergic synaptic dysregulation Experimental Neurology 2008 210 1 7 13
83. Stoltenberg M., Bush A. I., Bach G., Smidt K., Larsen A., Rungby J., Lund S., Doering P., Danscher G., Amyloid plaques arise from zinc-enriched cortical layers in APP/PS1 transgenic mice and are paradoxically enlarged with dietary zinc deficiency Neuroscience 2007 150 2 357 369
84. Kulstad J. J., McMillan P. J., Leverenz J. B., Cook D. G., Green P. S., Peskind E. R., Wilkinson C. W., Farris W., Mehta P. D., Craft S., Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque Journal of Neuropathology and Experimental Neurology 2005 64 2 139 146
85. Takeda A., Sakurada N., Kanno S., Ando M., Oku N., Vulnerability to seizures induced by potassium dyshomeostasis in the hippocampus in aged rats Journal of Health Science 2008 54 1 37 42
86. Mocchegiani E., Giacconi R., Cipriano C., Muti E., Gasparini N., Malavolta M., Are zinc-bound metallothionein isoforms (I+II and III) involved in impaired thymulin production and thymic involution during ageing? Immunity and Ageing 2004 1, article no. 5
87. Idei M., Miyake K., Horiuchi Y., Tabe Y., Miyake N., Ikeda N., Miida T., Serum zinc concentration decreases with age and is associated with anemia in middle-aged and elderly people Rinsho Byori 2010 58 3 205 210
88. Ricci A., Ramacci M. T., Ghirardi O., Amenta F., Age-related changes of the mossy fibre system in rat hippocampus: effect of long term acetyl-L-carnitine treatment Archives of Gerontology and Geriatrics 1989 8 1 63 71
89. Barili P., Fringuelli C., Ricci A., Rossodivita I., Sabbatini M., Age-related changes of sulphide-silver staining in the rat hippocampus Mechanisms of Ageing and Development 1997 99 2 83 94
90. Adlard P. A., Parncutt J. M., Finkelstein D. I., Bush A. I., Cognitive loss in zinc transporter-3 knock-out mice: a phenocopy for the synaptic and memory deficits of Alzheimer's disease? Journal of Neuroscience 2010 30 5 1631 1636
91. Landfield P. W., Eldridge J. C., Evolving aspects of the glucocorticoid hypothesis of brain aging: hormonal modulation of neuronal calcium homeostasis Neurobiology of Aging 1994 15 4 579 588
92. Ferrari E., Casarotti D., Muzzoni B., Albertelli N., Cravello L., Fioravanti M., Bruno Solerte S., Magri F., Age-related changes of the adrenal secretory pattern: possible role in pathological brain aging Brain Research Reviews 2001 37 13 294 300
93. Billard J. M., Ageing, hippocampal synaptic activity and magnesium Magnesium Research 2006 19 3 199 215
94. Foster T. C., Calcium homeostasis and modulation of synaptic plasticity in the aged brain Aging Cell 2007 6 3 319 325
95. Tamano H., Kan F., Kawamura M., Oku N., Takeda A., Behavior in the forced swim test and neurochemical changes in the hippocampus in young rats after 2-week zinc deprivation Neurochemistry International 2009 55 7 536 541
96. Csernansky J. G., Dong H., Fagan A. M., Wang L., Xiong C., Holtzman D. M., Morris J. C., Plasma cortisol and progression of dementia in subjects with Alzheimer-type dementia American Journal of Psychiatry 2006 163 12 2164 2169
97. Dong H., Csernansky J. G., Effects of stress and stress hormones on amyloid-beta protein and plaque deposition Journal of Alzheimer's Disease 2009 18 2 459 469
98. Dong J., Robertson J. D., Markesbery W. R., Lovell M. A., Serum zinc in the progression of Alzheimer's disease Journal of Alzheimer's Disease 2008 15 3 443 450
99. Deshpande A., Kawai H., Metherate R., Glabe C. G., Busciglio J., A role for synaptic zinc in activity-dependent a oligomer formation and accumulation at excitatory synapses Journal of Neuroscience 2009 29 13 4004 4015
100. Cuajungco M. P., Fagt K. Y., Zinc takes the center stage: its paradoxical role in Alzheimer's disease Brain Research Reviews 2003 41 1 44 56
101. Vasto S., Candore G., List F., Balistreri C. R., Colonna-Romano G., Malavolta M., Lio D., Nuzzo D., Mocchegiani E., Di Bona D., Caruso C., Inflammation, genes and zinc in Alzheimer's disease Brain Research Reviews 2008 58 1 96 105
102. Takeda A., Tamano H., Tochigi M., Oku N., Zinc homeostasis in the hippocampus of zinc-deficient young adult rats Neurochemistry International 2005 46 3 221 225
103. Colvin R. A., Bush A. I., Volitakis I., Fontaine C. P., Thomas D., Kikuchi K., Holmes W. R., Insights into Zn 2+ homeostasis in neurons from experimental and modeling studies American Journal of Physiology 2008 294 3 C726 C742
104. Maret W., Molecular aspects of human cellular zinc homeostasis: redox control of zinc potentials and zinc signals BioMetals 2009 22 1 149 157
105. Krezel A., Maret W., Thionein/metallothionein control Zn(II) availability and the activity of enzymes Journal of Biological Inorganic Chemistry 2008 13 3 401 409
106. Stork C. J., Li Y. V., Zinc release from thapsigargin/IP3-sensitive stores in cultured cortical neurons Journal of Molecular Signaling 2010 5, article no. 5
107. Maret W., Li Y., Coordination dynamics of zinc in proteins Chemical Reviews 2009 109 10 4682 4707
108. Vogt K., Mellor J., Tong G., Nicoll R., The actions of synaptically released zinc at hippocampal mossy fiber synapses Neuron 2000 26 1 187 196
109. Takeda A., Kanno S., Sakurada N., Ando M., Oku N., Attenuation of hippocampal mossy fiber long-term potentiation by low micromolar concentrations of zinc Journal of Neuroscience Research 2008 86 13 2906 2911
110. Takeda A., Fuke S., Ando M., Oku N., Positive modulation of long-term potentiation at hippocampal CA1 synapses by low micromolar concentrations of zinc Neuroscience 2009 158 2 585 591
111. Takeda A., Iwaki H., Ando M., Itagaki K., Suzuki M., Oku N., Zinc differentially acts on components of long-term potentiation at hippocampal CA1 synapses Brain Research 2010 1323 59 64
112. Duce J. A., Bush A. I., Biological metals and Alzheimer's disease: implications for therapeutics and diagnostics Progress in Neurobiology 2010 92 1 1 18