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Volumn 162, Issue 4, 2011, Pages 917-928

Melanocortins protect against multiple organ dysfunction syndrome in mice

Author keywords

cholinergic anti inflammatory pathway; melanocortin peptides; mouse; multiple organ dysfunction syndrome; nicotinic acetylcholine receptors

Indexed keywords

ALPHA INTERMEDIN; CHLORISONDAMINE; INTERLEUKIN 10; MELANOCORTIN; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN RECEPTOR ANTAGONIST; MESSENGER RNA; PHENYLALANINE DERIVATIVE; RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 79251521843     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01098.x     Document Type: Article
Times cited : (24)

References (60)
  • 1
    • 72149097863 scopus 로고    scopus 로고
    • Guide to Receptors and Channels (GRAC), 4th edition
    • (Suppl.).
    • Alexander SPH, Mathie A, Peters JA, (2009). Guide to Receptors and Channels (GRAC), 4th edition. Br J Pharmacol 158 (Suppl. 1): S1-S254.
    • (2009) Br J Pharmacol , vol.158 , Issue.1
    • Alexander, S.P.H.1    Mathie, A.2    Peters, J.A.3
  • 2
    • 0031868519 scopus 로고    scopus 로고
    • Tumour necrosis factor-a as a target of melanocortins in haemorrhagic shock, in the anaesthetized rat
    • Altavilla D, Cainazzo MM, Squadrito F, Guarini S, Bertolini A, Bazzani C, (1998). Tumour necrosis factor-a as a target of melanocortins in haemorrhagic shock, in the anaesthetized rat. Br J Pharmacol 124: 1587-1590.
    • (1998) Br J Pharmacol , vol.124 , pp. 1587-1590
    • Altavilla, D.1    Cainazzo, M.M.2    Squadrito, F.3    Guarini, S.4    Bertolini, A.5    Bazzani, C.6
  • 3
    • 33646816058 scopus 로고    scopus 로고
    • Activation of the cholinergic anti-infiammatory pathway reduces NF-kB activation, blunts TNF-α production, and protects against splanchnic artery occlusion shock
    • Altavilla D, Guarini S, Bitto A, Mioni C, Giuliani D, Bigiani A, et al. (2006). Activation of the cholinergic anti-infiammatory pathway reduces NF-kB activation, blunts TNF-α production, and protects against splanchnic artery occlusion shock. Shock 25: 500-506.
    • (2006) Shock , vol.25 , pp. 500-506
    • Altavilla, D.1    Guarini, S.2    Bitto, A.3    Mioni, C.4    Giuliani, D.5    Bigiani, A.6
  • 4
    • 0029097491 scopus 로고
    • Permeability of the blood-brain barrier to melanocortins
    • Banks WA, Kastin AJ, (1995). Permeability of the blood-brain barrier to melanocortins. Peptides 16: 1157-1161.
    • (1995) Peptides , vol.16 , pp. 1157-1161
    • Banks, W.A.1    Kastin, A.J.2
  • 5
    • 0030740131 scopus 로고    scopus 로고
    • Multiple organ failure, multiple organ dysfunction syndrome and systemic inflammatory response syndrome. Why no magic bullets?
    • Baue AE, (1997). Multiple organ failure, multiple organ dysfunction syndrome and systemic inflammatory response syndrome. Why no magic bullets? Arch Surg 132: 703-707.
    • (1997) Arch Surg , vol.132 , pp. 703-707
    • Baue, A.E.1
  • 6
    • 33750283880 scopus 로고    scopus 로고
    • MOF, MODS, and SIRS: What is in a name or an acronym?
    • Baue AE, (2006). MOF, MODS, and SIRS: what is in a name or an acronym? Shock 26: 438-449.
    • (2006) Shock , vol.26 , pp. 438-449
    • Baue, A.E.1
  • 8
    • 10244220967 scopus 로고    scopus 로고
    • Influence of ACTH-(1-24) and plasma hyperviscosity on free radical production and capillary perfusion after hemorrhagic shock
    • Bertuglia S, Giusti A, (2004). Influence of ACTH-(1-24) and plasma hyperviscosity on free radical production and capillary perfusion after hemorrhagic shock. Microcirculation 11: 227-238.
    • (2004) Microcirculation , vol.11 , pp. 227-238
    • Bertuglia, S.1    Giusti, A.2
  • 9
    • 0022510505 scopus 로고
    • Adrenal-independent, anti-shock effect of ACTH-(1-24) in rats
    • Bertolini A, Guarini S, Ferrari W, (1986a). Adrenal-independent, anti-shock effect of ACTH-(1-24) in rats. Eur J Pharmacol 122: 387-388.
    • (1986) Eur J Pharmacol , vol.122 , pp. 387-388
    • Bertolini, A.1    Guarini, S.2    Ferrari, W.3
  • 10
    • 0023037452 scopus 로고
    • MSH and other ACTH fragments improve cardiovascular function and survival in experimental hemorrhagic shock
    • Bertolini A, Guarini S, Rompianesi E, Ferrari W, (1986b).-MSH and other ACTH fragments improve cardiovascular function and survival in experimental hemorrhagic shock. Eur J Pharmacol 130: 19-26.
    • (1986) Eur J Pharmacol , vol.130 , pp. 19-26
    • Bertolini, A.1    Guarini, S.2    Rompianesi, E.3    Ferrari, W.4
  • 11
    • 0034713266 scopus 로고    scopus 로고
    • Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
    • Borovikova LV, Ivanova S, Zhang M, Yang H, Botchkina GI, Watkins LR, et al. (2000). Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 405: 458-462.
    • (2000) Nature , vol.405 , pp. 458-462
    • Borovikova, L.V.1    Ivanova, S.2    Zhang, M.3    Yang, H.4    Botchkina, G.I.5    Watkins, L.R.6
  • 12
    • 33846698560 scopus 로고    scopus 로고
    • The melanocortin system in leukocyte biology
    • Catania A, (2007). The melanocortin system in leukocyte biology. J Leukoc Biol 81: 383-392.
    • (2007) J Leukoc Biol , vol.81 , pp. 383-392
    • Catania, A.1
  • 13
    • 0034112590 scopus 로고    scopus 로고
    • Plasma concentrations and anti-cytokine effects of α-melanocyte stimulating hormone in septic patients
    • Catania A, Cutuli M, Garofalo L, Airaghi L, Valenza F, Lipton JM, et al. (2000). Plasma concentrations and anti-cytokine effects of α-melanocyte stimulating hormone in septic patients. Crit Care Med 28: 1403-1407.
    • (2000) Crit Care Med , vol.28 , pp. 1403-1407
    • Catania, A.1    Cutuli, M.2    Garofalo, L.3    Airaghi, L.4    Valenza, F.5    Lipton, J.M.6
  • 14
    • 1542347163 scopus 로고    scopus 로고
    • Targeting melanocortin receptors as a novel strategy to control inflammation
    • Catania A, Gatti S, Colombo G, Lipton JM, (2004). Targeting melanocortin receptors as a novel strategy to control inflammation. Pharmacol Rev 56: 1-29.
    • (2004) Pharmacol Rev , vol.56 , pp. 1-29
    • Catania, A.1    Gatti, S.2    Colombo, G.3    Lipton, J.M.4
  • 15
    • 0037180768 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis
    • Cohen J, (2002). The immunopathogenesis of sepsis. Nature 420: 885-891.
    • (2002) Nature , vol.420 , pp. 885-891
    • Cohen, J.1
  • 16
    • 73449095750 scopus 로고    scopus 로고
    • Science of self-preservation: How melanocortin action in the brain modulates body weight, blood pressure, and ischemic damage
    • Corander MP, Fenech M, Coll AP, (2009). Science of self-preservation: how melanocortin action in the brain modulates body weight, blood pressure, and ischemic damage. Circulation 120: 2260-2268.
    • (2009) Circulation , vol.120 , pp. 2260-2268
    • Corander, M.P.1    Fenech, M.2    Coll, A.P.3
  • 17
    • 13444265866 scopus 로고    scopus 로고
    • Adrenomedullin and its binding protein attenuate the proinflammatory response after hemorrhage
    • Cui X, Wu R, Zhou M, Dong W, Ulloa L, Yang H, et al. (2005). Adrenomedullin and its binding protein attenuate the proinflammatory response after hemorrhage. Crit Care Med 33: 391-398.
    • (2005) Crit Care Med , vol.33 , pp. 391-398
    • Cui, X.1    Wu, R.2    Zhou, M.3    Dong, W.4    Ulloa, L.5    Yang, H.6
  • 18
    • 0035144528 scopus 로고    scopus 로고
    • Beneficial effects of tempol, a membrane-permeable radical scavenger, on the multiple organ failure induced by zymosan in the rat
    • Cuzzocrea S, McDonald MC, Mazzon E, Filipe HM, Centorrino T, Lepore V, et al. (2001). Beneficial effects of tempol, a membrane-permeable radical scavenger, on the multiple organ failure induced by zymosan in the rat. Crit Care Med 29: 102-111.
    • (2001) Crit Care Med , vol.29 , pp. 102-111
    • Cuzzocrea, S.1    McDonald, M.C.2    Mazzon, E.3    Filipe, H.M.4    Centorrino, T.5    Lepore, V.6
  • 20
    • 33646814991 scopus 로고    scopus 로고
    • Targeting melanocortin receptors as potential novel therapeutics
    • Getting SJ, (2006). Targeting melanocortin receptors as potential novel therapeutics. Pharmacol Ther 111: 1-15.
    • (2006) Pharmacol Ther , vol.111 , pp. 1-15
    • Getting, S.J.1
  • 22
    • 32544461870 scopus 로고    scopus 로고
    • Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia
    • Giuliani D, Mioni C, Altavilla D, Leone S, Bazzani C, Minutoli L, et al. (2006b). Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia. Endocrinology 147: 1126-1135.
    • (2006) Endocrinology , vol.147 , pp. 1126-1135
    • Giuliani, D.1    Mioni, C.2    Altavilla, D.3    Leone, S.4    Bazzani, C.5    Minutoli, L.6
  • 23
    • 33847690196 scopus 로고    scopus 로고
    • Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage
    • Giuliani D, Mioni C, Bazzani C, Zaffe D, Botticelli AR, Capolongo S, et al. (2007). Selective melanocortin MC4 receptor agonists reverse haemorrhagic shock and prevent multiple organ damage. Br J Pharmacol 150: 595-603.
    • (2007) Br J Pharmacol , vol.150 , pp. 595-603
    • Giuliani, D.1    Mioni, C.2    Bazzani, C.3    Zaffe, D.4    Botticelli, A.R.5    Capolongo, S.6
  • 24
    • 67649836294 scopus 로고    scopus 로고
    • Functional recovery after delayed treatment of ischemic stroke with melanocortins is associated with overexpression of the activity-dependent gene Zif268
    • Giuliani D, Ottani A, Minutoli L, Di Stefano V, Galantucci M, Bitto A, et al. (2009). Functional recovery after delayed treatment of ischemic stroke with melanocortins is associated with overexpression of the activity-dependent gene Zif268. Brain Behav Immun 23: 844-850.
    • (2009) Brain Behav Immun , vol.23 , pp. 844-850
    • Giuliani, D.1    Ottani, A.2    Minutoli, L.3    Di Stefano, V.4    Galantucci, M.5    Bitto, A.6
  • 27
    • 0023195522 scopus 로고
    • Anti-shock effect of ACTH-(1-24): Comparison between intracerebroventricular and intravenous route of administration
    • Guarini S, Vergoni AV, Bertolini A, (1987). Anti-shock effect of ACTH-(1-24): comparison between intracerebroventricular and intravenous route of administration. Pharmacol Res Commun 19: 255-260.
    • (1987) Pharmacol Res Commun , vol.19 , pp. 255-260
    • Guarini, S.1    Vergoni, A.V.2    Bertolini, A.3
  • 28
    • 0025321929 scopus 로고
    • Early treatment with ACTH-(1-24) in a rat model of hemorrhagic shock prolongs survival and extends the time-limit for blood reinfusion to be effective
    • Guarini S, Tagliavini S, Bazzani C, Ferrari W, Bertolini A, (1990). Early treatment with ACTH-(1-24) in a rat model of hemorrhagic shock prolongs survival and extends the time-limit for blood reinfusion to be effective. Crit Care Med 18: 862-865.
    • (1990) Crit Care Med , vol.18 , pp. 862-865
    • Guarini, S.1    Tagliavini, S.2    Bazzani, C.3    Ferrari, W.4    Bertolini, A.5
  • 29
    • 0029835114 scopus 로고    scopus 로고
    • Influence of ACTH-(1-24) on free radical levels in the blood of haemorrhage-shocked rats: Direct ex vivo detection by electron spin resonance spectrometry
    • Guarini S, Bazzani C, Mattera Ricigliano G, Bini A, Tomasi A, Bertolini A, (1996). Influence of ACTH-(1-24) on free radical levels in the blood of haemorrhage-shocked rats: direct ex vivo detection by electron spin resonance spectrometry. Br J Pharmacol 119: 29-34.
    • (1996) Br J Pharmacol , vol.119 , pp. 29-34
    • Guarini, S.1    Bazzani, C.2    Mattera Ricigliano, G.3    Bini, A.4    Tomasi, A.5    Bertolini, A.6
  • 30
    • 0030793624 scopus 로고    scopus 로고
    • Resuscitating effect of melanocortin peptides after prolonged respiratory arrest
    • Guarini S, Bazzani C, Bertolini A, (1997a). Resuscitating effect of melanocortin peptides after prolonged respiratory arrest. Br J Pharmacol 121: 1454-1460.
    • (1997) Br J Pharmacol , vol.121 , pp. 1454-1460
    • Guarini, S.1    Bazzani, C.2    Bertolini, A.3
  • 32
    • 0032732610 scopus 로고    scopus 로고
    • Evidence that melanocortin 4 receptor mediates hemorrhagic shock reversal caused by melanocortin peptides
    • Guarini S, Bazzani C, Cainazzo MM, Mioni C, Ferrazza G, Vergoni AV, et al. (1999). Evidence that melanocortin 4 receptor mediates hemorrhagic shock reversal caused by melanocortin peptides. J Pharmacol Exp Ther 291: 1023-1027.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 1023-1027
    • Guarini, S.1    Bazzani, C.2    Cainazzo, M.M.3    Mioni, C.4    Ferrazza, G.5    Vergoni, A.V.6
  • 33
    • 0037418233 scopus 로고    scopus 로고
    • Efferent vagal fibre stimulation blunts NF-kB activation and protects against hypovolemic hemorrhagic shock
    • Guarini S, Altavilla D, Cainazzo MM, Giuliani D, Bigiani A, Marini H, et al. (2003). Efferent vagal fibre stimulation blunts NF-kB activation and protects against hypovolemic hemorrhagic shock. Circulation 107: 1189-1194.
    • (2003) Circulation , vol.107 , pp. 1189-1194
    • Guarini, S.1    Altavilla, D.2    Cainazzo, M.M.3    Giuliani, D.4    Bigiani, A.5    Marini, H.6
  • 34
    • 19244365947 scopus 로고    scopus 로고
    • Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal anti-inflammatory pathway
    • Guarini S, Cainazzo MM, Giuliani D, Mioni C, Altavilla D, Marini H, et al. (2004). Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal anti-inflammatory pathway. Cardiovasc Res 63: 357-365.
    • (2004) Cardiovasc Res , vol.63 , pp. 357-365
    • Guarini, S.1    Cainazzo, M.M.2    Giuliani, D.3    Mioni, C.4    Altavilla, D.5    Marini, H.6
  • 35
    • 0031252283 scopus 로고    scopus 로고
    • Gradual development of organ damage in the murine zymosan-induced multiple organ dysfunction syndrome
    • Jansen MJ, Hendriks T, Verhofstad AA, Lange W, Geeraedts LMJ, Goris RJ, (1997). Gradual development of organ damage in the murine zymosan-induced multiple organ dysfunction syndrome. Shock 8: 261-267.
    • (1997) Shock , vol.8 , pp. 261-267
    • Jansen, M.J.1    Hendriks, T.2    Verhofstad, A.A.3    Lange, W.4    Geeraedts, L.M.J.5    Goris, R.J.6
  • 36
    • 1942439783 scopus 로고    scopus 로고
    • Involvement of proopiomelanocortin-derived peptides in endogenous central istamine-induced reversal of critical haemorrhagic hypotension in rats
    • Jochem J, (2004). Involvement of proopiomelanocortin-derived peptides in endogenous central istamine-induced reversal of critical haemorrhagic hypotension in rats. J Physiol Pharmacol 55: 57-71.
    • (2004) J Physiol Pharmacol , vol.55 , pp. 57-71
    • Jochem, J.1
  • 37
    • 0028618822 scopus 로고
    • Antiinflammatory effects of the neuropeptide α-MSH in acute, chronic, and systemic inflammation
    • Lipton JM, Ceriani G, Macaluso A, McCoy D, Carnes K, Biltz J, et al. (1994). Antiinflammatory effects of the neuropeptide α-MSH in acute, chronic, and systemic inflammation. Ann NY Acad Sci 741: 137-148.
    • (1994) Ann NY Acad Sci , vol.741 , pp. 137-148
    • Lipton, J.M.1    Ceriani, G.2    MacAluso, A.3    McCoy, D.4    Carnes, K.5    Biltz, J.6
  • 38
    • 0037351537 scopus 로고    scopus 로고
    • α-Melanocyte-stimulating hormone is decreased in plasma of patients with acute brain injury
    • Magnoni S, Stocchetti N, Colombo G, Carlin A, Colombo A, Lipton JM, et al. (2003). α-Melanocyte-stimulating hormone is decreased in plasma of patients with acute brain injury. J Neurotrauma 20: 251-260.
    • (2003) J Neurotrauma , vol.20 , pp. 251-260
    • Magnoni, S.1    Stocchetti, N.2    Colombo, G.3    Carlin, A.4    Colombo, A.5    Lipton, J.M.6
  • 39
    • 38349094193 scopus 로고    scopus 로고
    • Early organ-specific endothelial activation during hemorrhagic shock and resuscitation
    • van Meurs M, Wulfert FM, Knol AJ, De Haes A, Houwertjes M, Aarts LP, et al. (2008). Early organ-specific endothelial activation during hemorrhagic shock and resuscitation. Shock 29: 291-299.
    • (2008) Shock , vol.29 , pp. 291-299
    • Van Meurs, M.1    Wulfert, F.M.2    Knol, A.J.3    De Haes, A.4    Houwertjes, M.5    Aarts, L.P.6
  • 40
    • 27944443181 scopus 로고    scopus 로고
    • Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in rats
    • Mioni C, Bazzani C, Giuliani D, Altavilla D, Leone S, Ferrari A, et al. (2005). Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in rats. Crit Care Med 33: 2621-2628.
    • (2005) Crit Care Med , vol.33 , pp. 2621-2628
    • Mioni, C.1    Bazzani, C.2    Giuliani, D.3    Altavilla, D.4    Leone, S.5    Ferrari, A.6
  • 41
    • 0035845258 scopus 로고    scopus 로고
    • Survival rate after early treatment for acute type-A aortic dissection with ACTH-(1-24)
    • Noera G, Lamarra M, Guarini S, Bertolini A, (2001). Survival rate after early treatment for acute type-A aortic dissection with ACTH-(1-24). Lancet 358: 469-470.
    • (2001) Lancet , vol.358 , pp. 469-470
    • Noera, G.1    Lamarra, M.2    Guarini, S.3    Bertolini, A.4
  • 42
    • 61349113951 scopus 로고    scopus 로고
    • Vagus nerve mediates the protective effects of melanocortins against cerebral and systemic damage after ischemic stroke
    • Ottani A, Giuliani D, Mioni C, Galantucci M, Minutoli L, Bitto A, et al. (2009). Vagus nerve mediates the protective effects of melanocortins against cerebral and systemic damage after ischemic stroke. J Cereb Blood Flow Metab 29: 512-523.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 512-523
    • Ottani, A.1    Giuliani, D.2    Mioni, C.3    Galantucci, M.4    Minutoli, L.5    Bitto, A.6
  • 43
    • 77953288401 scopus 로고    scopus 로고
    • Melanocortins counteract inflammatory and apoptotic responses to prolonged myocardial ischemia/reperfusion through a vagus nerve-mediated mechanism
    • Ottani A, Giuliani D, Galantucci M, Spaccapelo L, Novellino E, Grieco P, et al. (2010). Melanocortins counteract inflammatory and apoptotic responses to prolonged myocardial ischemia/reperfusion through a vagus nerve-mediated mechanism. Eur J Pharmacol 637: 124-130.
    • (2010) Eur J Pharmacol , vol.637 , pp. 124-130
    • Ottani, A.1    Giuliani, D.2    Galantucci, M.3    Spaccapelo, L.4    Novellino, E.5    Grieco, P.6
  • 44
    • 0027272339 scopus 로고
    • Involvement of oxygen radicals in shock related cell injury
    • Redl H, Gasser H, Schlag G, Marzi I, (1993). Involvement of oxygen radicals in shock related cell injury. Br Med Bull 49: 556-565.
    • (1993) Br Med Bull , vol.49 , pp. 556-565
    • Redl, H.1    Gasser, H.2    Schlag, G.3    Marzi, I.4
  • 45
    • 66149103723 scopus 로고    scopus 로고
    • Cholinergic control of inflammation
    • Rosas-Ballina M, Tracey KJ, (2009). Cholinergic control of inflammation. J Intern Med 265: 663-679.
    • (2009) J Intern Med , vol.265 , pp. 663-679
    • Rosas-Ballina, M.1    Tracey, K.J.2
  • 46
    • 0025793165 scopus 로고
    • The cell in shock: The origin of multiple organ failure
    • Schlag G, Redl H, Hallström S, (1991). The cell in shock: the origin of multiple organ failure. Resuscitation 21: 137-180.
    • (1991) Resuscitation , vol.21 , pp. 137-180
    • Schlag, G.1    Redl, H.2    Hallström, S.3
  • 47
    • 0031802293 scopus 로고    scopus 로고
    • Cytokine and adhesion molecules in elective and accidental trauma-related ischaemia/reperfusion
    • Seekamp AJ, Jochum M, Ziegler M, Micheal M, Gerd R, (1998). Cytokine and adhesion molecules in elective and accidental trauma-related ischaemia/reperfusion. J Trauma 44: 874-882.
    • (1998) J Trauma , vol.44 , pp. 874-882
    • Seekamp, A.J.1    Jochum, M.2    Ziegler, M.3    Micheal, M.4    Gerd, R.5
  • 48
    • 0029858536 scopus 로고    scopus 로고
    • Elevated selectin levels after severe trauma: A marker for sepsis and organ failure and a potential target for immunomodulatory therapy
    • Simons RK, Hoyt DB, Winchell RJ, Rose RM, Holbrook T, (1996). Elevated selectin levels after severe trauma: a marker for sepsis and organ failure and a potential target for immunomodulatory therapy. J Trauma 41: 653-662.
    • (1996) J Trauma , vol.41 , pp. 653-662
    • Simons, R.K.1    Hoyt, D.B.2    Winchell, R.J.3    Rose, R.M.4    Holbrook, T.5
  • 49
    • 0032698847 scopus 로고    scopus 로고
    • Adrenocorticotropin reverses vascular dysfunction and protects against splanchnic artery occlusion shock
    • Squadrito F, Guarini S, Altavilla D, Squadrito G, Campo GM, Arlotta M, et al. (1999). Adrenocorticotropin reverses vascular dysfunction and protects against splanchnic artery occlusion shock. Br J Pharmacol 128: 816-822.
    • (1999) Br J Pharmacol , vol.128 , pp. 816-822
    • Squadrito, F.1    Guarini, S.2    Altavilla, D.3    Squadrito, G.4    Campo, G.M.5    Arlotta, M.6
  • 50
    • 0015788993 scopus 로고
    • Sequential system failure after rupture of abdominal aortic aneurysms: An unsolved problem in postoperative care
    • Tilney NL, Bailey GL, Morgan AP, (1973). Sequential system failure after rupture of abdominal aortic aneurysms: an unsolved problem in postoperative care. Ann Surg 178: 117-122.
    • (1973) Ann Surg , vol.178 , pp. 117-122
    • Tilney, N.L.1    Bailey, G.L.2    Morgan, A.P.3
  • 52
    • 0037180778 scopus 로고    scopus 로고
    • The inflammatory reflex
    • Tracey KJ, (2002). The inflammatory reflex. Nature 420: 853-859.
    • (2002) Nature , vol.420 , pp. 853-859
    • Tracey, K.J.1
  • 53
    • 33846817498 scopus 로고    scopus 로고
    • Physiology and immunology of the cholinergic antiinflammatory pathway
    • Tracey KJ, (2007). Physiology and immunology of the cholinergic antiinflammatory pathway. J Clin Invest 117: 289-296.
    • (2007) J Clin Invest , vol.117 , pp. 289-296
    • Tracey, K.J.1
  • 54
    • 71649094123 scopus 로고    scopus 로고
    • Current theories on the pathophysiology of multiple organ failure after trauma
    • Tsukamoto T, Chanthaphavong RS, Pape HC, (2010). Current theories on the pathophysiology of multiple organ failure after trauma. Injury 41: 21-26.
    • (2010) Injury , vol.41 , pp. 21-26
    • Tsukamoto, T.1    Chanthaphavong, R.S.2    Pape, H.C.3
  • 55
    • 0038206536 scopus 로고    scopus 로고
    • The administration of α-melanocyte-stimulating hormone protects the ischemic/reperfused myocardium
    • Vecsernyes M, Juhasz B, Der P, Kocsan R, Feher P, Bacskay I, et al. (2003). The administration of α-melanocyte-stimulating hormone protects the ischemic/reperfused myocardium. Eur J Pharmacol 470: 177-183.
    • (2003) Eur J Pharmacol , vol.470 , pp. 177-183
    • Vecsernyes, M.1    Juhasz, B.2    Der, P.3    Kocsan, R.4    Feher, P.5    Bacskay, I.6
  • 56
    • 0036310110 scopus 로고    scopus 로고
    • Organ damage in zymosan-induced multiple organ dysfunction syndrome in mice is not mediated by inducible nitric oxide synthase
    • Volman TJ, Goris RJ, van der Jagt M, van de Loo FA, Hendriks T, (2002). Organ damage in zymosan-induced multiple organ dysfunction syndrome in mice is not mediated by inducible nitric oxide synthase. Crit Care Med 30: 1553-1559.
    • (2002) Crit Care Med , vol.30 , pp. 1553-1559
    • Volman, T.J.1    Goris, R.J.2    Van Der Jagt, M.3    Van De Loo, F.A.4    Hendriks, T.5
  • 57
    • 3042662412 scopus 로고    scopus 로고
    • Tissue- and time-dependent upregulation of cytokine mRNA in a murine model for the multiple organ dysfunction syndrome
    • Volman TJ, Goris RJ, van der Meer JW, Hendriks T, (2004). Tissue- and time-dependent upregulation of cytokine mRNA in a murine model for the multiple organ dysfunction syndrome. Ann Surg 240: 142-150.
    • (2004) Ann Surg , vol.240 , pp. 142-150
    • Volman, T.J.1    Goris, R.J.2    Van Der Meer, J.W.3    Hendriks, T.4
  • 58
    • 16244372427 scopus 로고    scopus 로고
    • Zymosan-induced generalized inflammation: Experimental studies into mechanisms leading to multiple organ dysfunction syndrome
    • Volman TJ, Hendriks T, Goris RJ, (2005). Zymosan-induced generalized inflammation: experimental studies into mechanisms leading to multiple organ dysfunction syndrome. Shock 23: 291-297.
    • (2005) Shock , vol.23 , pp. 291-297
    • Volman, T.J.1    Hendriks, T.2    Goris, R.J.3
  • 59
    • 0033590515 scopus 로고    scopus 로고
    • Treating patients with severe sepsis
    • Wheeler AP, Bernard GR, (1999). Treating patients with severe sepsis. N Engl J Med 340: 207-214.
    • (1999) N Engl J Med , vol.340 , pp. 207-214
    • Wheeler, A.P.1    Bernard, G.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.