Melanocortins counteract inflammatory and apoptotic responses to prolonged myocardial ischemia/reperfusion through a vagus nerve-mediated mechanism

European Journal of Pharmacology

Volumn 637, Issue 1-3, 2010, Pages 124-130

  Ottani, Alessandra ^a   Giuliani, Daniela ^a   Galantucci, Maria ^a   Spaccapelo, Luca ^a   Novellino, Ettore ^b   Grieco, Paolo ^b   Jochem, Jerzy ^c   Guarini, Salvatore ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Apoptosis; Cardioprotection; Inflammation; Melanocortin; Myocardial ischemia reperfusion; Vagus nerve

Indexed keywords

ALPHA INTERMEDIN DERIVATIVE; CASPASE 3; INTERMEDIN; MELANOCORTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NORLEUCINE DEXTRO PHENYLALANINE ALPHA INTERMEDIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART INFARCTION SIZE; HEART LEFT VENTRICLE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; VAGOTOMY; VAGUS NERVE STIMULATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INFLAMMATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MELANOCORTINS; MYOCARDIAL REPERFUSION INJURY; RATS; RATS, WISTAR; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; VAGUS NERVE;

EID: 77953288401     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.03.052     Document Type: Article

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