메뉴 건너뛰기




Volumn 5, Issue 12, 2010, Pages

A knowledge-based weighting framework to boost the power of genome-wide association studies

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; BIOINFORMATICS; COMPUTER SIMULATION; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; DNA REPLICATION; EXTENSION GENE; GENE FUNCTION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC MODEL; GENETIC RISK; HUMAN; HYPOTHESIS; INTERMETHOD COMPARISON; KNOWLEDGE BASE; POWER ANALYSIS; SAMPLE SIZE; SINGLE NUCLEOTIDE POLYMORPHISM; BINDING SITE; BIOLOGICAL MODEL; BIOLOGY; COMPUTER PROGRAM; GENETIC PREDISPOSITION; GENETICS; GENOMICS; HUMAN GENOME; METABOLISM; METHODOLOGY; STATISTICAL MODEL;

EID: 79251484337     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014480     Document Type: Article
Times cited : (43)

References (56)
  • 1
    • 42349112088 scopus 로고    scopus 로고
    • Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
    • McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, et al. (2008) Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 9: 356-369.
    • (2008) Nat Rev Genet , vol.9 , pp. 356-369
    • McCarthy, M.I.1    Abecasis, G.R.2    Cardon, L.R.3    Goldstein, D.B.4    Little, J.5
  • 2
    • 43049146524 scopus 로고    scopus 로고
    • A HapMap harvest of insights into the genetics of common disease
    • Manolio TA, Brooks LD, Collins FS (2008) A HapMap harvest of insights into the genetics of common disease. J Clin Invest 118: 1590-1605.
    • (2008) J Clin Invest , vol.118 , pp. 1590-1605
    • Manolio, T.A.1    Brooks, L.D.2    Collins, F.S.3
  • 3
    • 34347335667 scopus 로고    scopus 로고
    • Guilt beyond a reasonable doubt
    • Altshuler D, Daly M (2007) Guilt beyond a reasonable doubt. Nat Genet 39: 813-815.
    • (2007) Nat Genet , vol.39 , pp. 813-815
    • Altshuler, D.1    Daly, M.2
  • 4
    • 33845892752 scopus 로고    scopus 로고
    • Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
    • Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE (2007) Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet 39: 17-23.
    • (2007) Nat Genet , vol.39 , pp. 17-23
    • Bertram, L.1    McQueen, M.B.2    Mullin, K.3    Blacker, D.4    Tanzi, R.E.5
  • 5
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Consortium WTCC
    • Consortium WTCC (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 6
    • 62549085618 scopus 로고    scopus 로고
    • Human genetic variation and its contribution to complex traits
    • Frazer KA, Murray SS, Schork NJ, Topol EJ (2009) Human genetic variation and its contribution to complex traits. Nat Rev Genet 10: 241-251.
    • (2009) Nat Rev Genet , vol.10 , pp. 241-251
    • Frazer, K.A.1    Murray, S.S.2    Schork, N.J.3    Topol, E.J.4
  • 7
    • 0036255811 scopus 로고    scopus 로고
    • Candidate-gene approaches for studying complex genetic traits: Practical considerations
    • Tabor HK, Risch NJ, Myers RM (2002) Candidate-gene approaches for studying complex genetic traits: practical considerations. Nat Rev Genet 3: 391-397.
    • (2002) Nat Rev Genet , vol.3 , pp. 391-397
    • Tabor, H.K.1    Risch, N.J.2    Myers, R.M.3
  • 8
    • 49649089565 scopus 로고    scopus 로고
    • Exhaustive prediction of disease susceptibility to coding base changes in the human genome
    • Kulkarni V, Errami M, Barber R, Garner HR (2008) Exhaustive prediction of disease susceptibility to coding base changes in the human genome. BMC Bioinformatics 9(Suppl 9): S3.
    • (2008) BMC Bioinformatics , vol.9 , Issue.SUPPL. 9
    • Kulkarni, V.1    Errami, M.2    Barber, R.3    Garner, H.R.4
  • 9
    • 45449101500 scopus 로고    scopus 로고
    • Natural selection on genes that underlie human disease susceptibility
    • Blekhman R, Man O, Herrmann L, Boyko AR, Indap A, et al. (2008) Natural selection on genes that underlie human disease susceptibility. Curr Biol 18: 883-889.
    • (2008) Curr Biol , vol.18 , pp. 883-889
    • Blekhman, R.1    Man, O.2    Herrmann, L.3    Boyko, A.R.4    Indap, A.5
  • 10
    • 54849408182 scopus 로고    scopus 로고
    • An analysis of human microRNA and disease associations
    • Lu M, Zhang Q, Deng M, Miao J, Guo Y, et al. (2008) An analysis of human microRNA and disease associations. PLoS ONE 3: e3420.
    • (2008) PLoS ONE , vol.3
    • Lu, M.1    Zhang, Q.2    Deng, M.3    Miao, J.4    Guo, Y.5
  • 11
    • 52949119537 scopus 로고    scopus 로고
    • MicroRNA target site polymorphisms and human disease
    • Sethupathy P, Collins FS (2008) MicroRNA target site polymorphisms and human disease. Trends Genet 24: 489-497.
    • (2008) Trends Genet , vol.24 , pp. 489-497
    • Sethupathy, P.1    Collins, F.S.2
  • 12
    • 33644871186 scopus 로고    scopus 로고
    • TAMAL: An integrated approach to choosing SNPs for genetic studies of human complex traits
    • Hemminger BM, Saelim B, Sullivan PF (2006) TAMAL: an integrated approach to choosing SNPs for genetic studies of human complex traits. Bioinformatics 22: 626-627.
    • (2006) Bioinformatics , vol.22 , pp. 626-627
    • Hemminger, B.M.1    Saelim, B.2    Sullivan, P.F.3
  • 13
    • 33748672451 scopus 로고    scopus 로고
    • SNPeffect v2.0: A new step in investigating the molecular phenotypic effects of human nonsynonymous SNPs
    • Reumers J, Maurer-Stroh S, Schymkowitz J, Rousseau F (2006) SNPeffect v2.0: a new step in investigating the molecular phenotypic effects of human nonsynonymous SNPs. Bioinformatics 22: 2183-2185.
    • (2006) Bioinformatics , vol.22 , pp. 2183-2185
    • Reumers, J.1    Maurer-Stroh, S.2    Schymkowitz, J.3    Rousseau, F.4
  • 14
    • 33747871385 scopus 로고    scopus 로고
    • SNP Function Portal: A web database for exploring the function implication of SNP alleles
    • Wang PL, Dai MH, Xuan WJ, McEachin RC, Jackson AU, et al. (2006) SNP Function Portal: a web database for exploring the function implication of SNP alleles. Bioinformatics 22: E523-E529.
    • (2006) Bioinformatics , vol.22
    • Wang, P.L.1    Dai, M.H.2    Xuan, W.J.3    McEachin, R.C.4    Jackson, A.U.5
  • 15
    • 33845545435 scopus 로고    scopus 로고
    • The modular nature of genetic diseases
    • Oti M, Brunner HG (2007) The modular nature of genetic diseases. Clin Genet 71: 1-11.
    • (2007) Clin Genet , vol.71 , pp. 1-11
    • Oti, M.1    Brunner, H.G.2
  • 16
    • 33947095027 scopus 로고    scopus 로고
    • A human phenome-interactome network of protein complexes implicated in genetic disorders
    • Lage K, Karlberg EO, Storling ZM, Olason PI, Pedersen AG, et al. (2007) A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol 25: 309-316.
    • (2007) Nat Biotechnol , vol.25 , pp. 309-316
    • Lage, K.1    Karlberg, E.O.2    Storling, Z.M.3    Olason, P.I.4    Pedersen, A.G.5
  • 17
    • 36248962105 scopus 로고    scopus 로고
    • The genomic landscapes of human breast and colorectal cancers
    • Wood LD, Parsons DW, Jones S, Lin J, Sjoblom T, et al. (2007) The genomic landscapes of human breast and colorectal cancers. Science 318: 1108-1113.
    • (2007) Science , vol.318 , pp. 1108-1113
    • Wood, L.D.1    Parsons, D.W.2    Jones, S.3    Lin, J.4    Sjoblom, T.5
  • 18
    • 33646687963 scopus 로고    scopus 로고
    • A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration
    • Lim J, Hao T, Shaw C, Patel AJ, Szabo G, et al. (2006) A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Cell 125: 801-814.
    • (2006) Cell , vol.125 , pp. 801-814
    • Lim, J.1    Hao, T.2    Shaw, C.3    Patel, A.J.4    Szabo, G.5
  • 19
    • 33646884801 scopus 로고    scopus 로고
    • Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genes
    • Franke L, van Bakel H, Fokkens L, de Jong ED, Egmont-Petersen M, et al. (2006) Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genes. Am J Hum Genet 78: 1011-1025.
    • (2006) Am J Hum Genet , vol.78 , pp. 1011-1025
    • Franke, L.1    van Bakel, H.2    Fokkens, L.3    de Jong, E.D.4    Egmont-Petersen, M.5
  • 21
    • 41549139527 scopus 로고    scopus 로고
    • Walking the interactome for prioritization of candidate disease genes
    • Kohler S, Bauer S, Horn D, Robinson PN (2008) Walking the interactome for prioritization of candidate disease genes. Am J Hum Genet 82: 949-958.
    • (2008) Am J Hum Genet , vol.82 , pp. 949-958
    • Kohler, S.1    Bauer, S.2    Horn, D.3    Robinson, P.N.4
  • 22
    • 43249114206 scopus 로고    scopus 로고
    • Network-based global inference of human disease genes
    • Wu X, Jiang R, Zhang MQ, Li S (2008) Network-based global inference of human disease genes. Mol Syst Biol 4: 189.
    • (2008) Mol Syst Biol , vol.4 , pp. 189
    • Wu, X.1    Jiang, R.2    Zhang, M.Q.3    Li, S.4
  • 23
  • 24
    • 0002294347 scopus 로고
    • A Simple Sequentially Rejective Multiple Test Procedure
    • Holm S (1979) A Simple Sequentially Rejective Multiple Test Procedure. Scandinavian Journal of Statistics 6: 65-70.
    • (1979) Scandinavian Journal of Statistics , vol.6 , pp. 65-70
    • Holm, S.1
  • 26
    • 33750168129 scopus 로고    scopus 로고
    • False discovery control with pvalue weighting
    • Genovese CR, Roeder K, Wasserman L (2006) False discovery control with pvalue weighting. Biometrika 93: 509-524.
    • (2006) Biometrika , vol.93 , pp. 509-524
    • Genovese, C.R.1    Roeder, K.2    Wasserman, L.3
  • 27
    • 36248977635 scopus 로고    scopus 로고
    • Improving power in genome-wide association studies: Weights tip the scale
    • Roeder K, Devlin B, Wasserman L (2007) Improving power in genome-wide association studies: weights tip the scale. Genet Epidemiol 31: 741-747.
    • (2007) Genet Epidemiol , vol.31 , pp. 741-747
    • Roeder, K.1    Devlin, B.2    Wasserman, L.3
  • 29
    • 34147122065 scopus 로고    scopus 로고
    • Mendelian Inheritance in Man and its online version, OMIM
    • McKusick VA (2007) Mendelian Inheritance in Man and its online version, OMIM. Am J Hum Genet 80: 588-604.
    • (2007) Am J Hum Genet , vol.80 , pp. 588-604
    • McKusick, V.A.1
  • 30
    • 44849132693 scopus 로고    scopus 로고
    • Physiology, pathology and relatedness of human tissues from gene expression meta-analysis
    • Greco D, Somervuo P, Di Lieto A, Raitila T, Nitsch L, et al. (2008) Physiology, pathology and relatedness of human tissues from gene expression meta-analysis. PLoS ONE 3: e1880.
    • (2008) PLoS ONE , vol.3
    • Greco, D.1    Somervuo, P.2    Di, L.A.3    Raitila, T.4    Nitsch, L.5
  • 31
    • 10744224197 scopus 로고    scopus 로고
    • Development of human protein reference database as an initial platform for approaching systems biology in humans
    • Peri S, Navarro JD, Amanchy R, Kristiansen TZ, Jonnalagadda CK, et al. (2003) Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res 13: 2363-2371.
    • (2003) Genome Res , vol.13 , pp. 2363-2371
    • Peri, S.1    Navarro, J.D.2    Amanchy, R.3    Kristiansen, T.Z.4    Jonnalagadda, C.K.5
  • 32
    • 34548855730 scopus 로고    scopus 로고
    • Unequal evolutionary conservation of human protein interactions in interologous networks
    • Brown KR, Jurisica I (2007) Unequal evolutionary conservation of human protein interactions in interologous networks. Genome Biol 8: R95.
    • (2007) Genome Biol , vol.8
    • Brown, K.R.1    Jurisica, I.2
  • 33
    • 0037245913 scopus 로고    scopus 로고
    • BIND: The Biomolecular Interaction Network Database
    • Bader GD, Betel D, Hogue CW (2003) BIND: the Biomolecular Interaction Network Database. Nucleic Acids Res 31: 248-250.
    • (2003) Nucleic Acids Res , vol.31 , pp. 248-250
    • Bader, G.D.1    Betel, D.2    Hogue, C.W.3
  • 35
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R (2003) Statistical significance for genomewide studies. Proc Natl Acad Sci U S A 100: 9440-9445.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 36
    • 62049083651 scopus 로고    scopus 로고
    • Inference of non-centrality parameter of a truncated noncentral chi-squared distribution
    • Li QZ, Yu K (2009) Inference of non-centrality parameter of a truncated noncentral chi-squared distribution. Journal of Statistical Planning and Inference 139: 2431-2444.
    • (2009) Journal of Statistical Planning and Inference , vol.139 , pp. 2431-2444
    • Li, Q.Z.1    Yu, K.2
  • 38
    • 0345822598 scopus 로고    scopus 로고
    • The positive false discovery rate: A Bayesian interpretation and the q-value
    • Storey JD (2003) The positive false discovery rate: A Bayesian interpretation and the q-value. The Annals of Statistics 31: 2013-2035.
    • (2003) The Annals of Statistics , vol.31 , pp. 2013-2035
    • Storey, J.D.1
  • 39
    • 33845879059 scopus 로고    scopus 로고
    • SNiPer-HD: Improved genotype calling accuracy by an expectation-maximization algorithm for high-density SNP arrays
    • Hua J, Craig DW, Brun M, Webster J, Zismann V, et al. (2007) SNiPer-HD: improved genotype calling accuracy by an expectation-maximization algorithm for high-density SNP arrays. Bioinformatics 23: 57-63.
    • (2007) Bioinformatics , vol.23 , pp. 57-63
    • Hua, J.1    Craig, D.W.2    Brun, M.3    Webster, J.4    Zismann, V.5
  • 40
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.5
  • 42
    • 34249745769 scopus 로고    scopus 로고
    • GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers
    • Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, et al. (2007) GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron 54: 713-720.
    • (2007) Neuron , vol.54 , pp. 713-720
    • Reiman, E.M.1    Webster, J.A.2    Myers, A.J.3    Hardy, J.4    Dunckley, T.5
  • 43
    • 19944428425 scopus 로고    scopus 로고
    • Genotypes and haplotypes in the IL-1 gene cluster: Analysis of two genetically and diagnostically distinct groups of Alzheimer patients
    • Seripa D, Matera MG, Dal Forno G, Gravina C, Masullo C, et al. (2005) Genotypes and haplotypes in the IL-1 gene cluster: analysis of two genetically and diagnostically distinct groups of Alzheimer patients. Neurobiol Aging 26: 455-464.
    • (2005) Neurobiol Aging , vol.26 , pp. 455-464
    • Seripa, D.1    Matera, M.G.2    Dal, F.G.3    Gravina, C.4    Masullo, C.5
  • 44
    • 49649119504 scopus 로고    scopus 로고
    • Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases
    • Reynolds CH, Garwood CJ, Wray S, Price C, Kellie S, et al. (2008) Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases. J Biol Chem 283: 18177-18186.
    • (2008) J Biol Chem , vol.283 , pp. 18177-18186
    • Reynolds, C.H.1    Garwood, C.J.2    Wray, S.3    Price, C.4    Kellie, S.5
  • 45
    • 34250304714 scopus 로고    scopus 로고
    • Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling
    • Nizzari M, Venezia V, Repetto E, Caorsi V, Magrassi R, et al. (2007) Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling. J Biol Chem 282: 13833-13844.
    • (2007) J Biol Chem , vol.282 , pp. 13833-13844
    • Nizzari, M.1    Venezia, V.2    Repetto, E.3    Caorsi, V.4    Magrassi, R.5
  • 46
    • 20144388360 scopus 로고    scopus 로고
    • Identification of hippocampus-related candidate genes for Alzheimer's disease
    • Taguchi K, Yamagata HD, Zhong W, Kamino K, Akatsu H, et al. (2005) Identification of hippocampus-related candidate genes for Alzheimer's disease. Ann Neurol 57: 585-588.
    • (2005) Ann Neurol , vol.57 , pp. 585-588
    • Taguchi, K.1    Yamagata, H.D.2    Zhong, W.3    Kamino, K.4    Akatsu, H.5
  • 47
    • 45249117227 scopus 로고    scopus 로고
    • Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating
    • Cheung KH, Shineman D, Muller M, Cardenas C, Mei L, et al. (2008) Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating. Neuron 58: 871-883.
    • (2008) Neuron , vol.58 , pp. 871-883
    • Cheung, K.H.1    Shineman, D.2    Muller, M.3    Cardenas, C.4    Mei, L.5
  • 48
    • 45749130981 scopus 로고    scopus 로고
    • A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk
    • Dreses-Werringloer U, Lambert JC, Vingtdeux V, Zhao H, Vais H, et al. (2008) A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. Cell 133: 1149-1161.
    • (2008) Cell , vol.133 , pp. 1149-1161
    • Dreses-Werringloer, U.1    Lambert, J.C.2    Vingtdeux, V.3    Zhao, H.4    Vais, H.5
  • 49
    • 0036830947 scopus 로고    scopus 로고
    • Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
    • LaFerla FM (2002) Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat Rev Neurosci 3: 862-872.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 862-872
    • Laferla, F.M.1
  • 50
    • 61449106698 scopus 로고    scopus 로고
    • Optimal multistage designs-a general framework for efficient genome-wide association studies
    • Pahl R, Schafer H, Muller HH (2009) Optimal multistage designs-a general framework for efficient genome-wide association studies. Biostatistics 10: 297-309.
    • (2009) Biostatistics , vol.10 , pp. 297-309
    • Pahl, R.1    Schafer, H.2    Muller, H.H.3
  • 51
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K (1996) The future of genetic studies of complex human diseases. Science 273: 1516-1517.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 52
    • 60549101350 scopus 로고    scopus 로고
    • GAB2 as an Alzheimer disease susceptibility gene: Follow-up of genomewide association results
    • Schjeide BM, Hooli B, Parkinson M, Hogan MF, DiVito J, et al. (2009) GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results. Arch Neurol 66: 250-254.
    • (2009) Arch Neurol , vol.66 , pp. 250-254
    • Schjeide, B.M.1    Hooli, B.2    Parkinson, M.3    Hogan, M.F.4    Divito, J.5
  • 53
    • 70349558522 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
    • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, et al. (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 41: 1088-1093.
    • (2009) Nat Genet , vol.41 , pp. 1088-1093
    • Harold, D.1    Abraham, R.2    Hollingworth, P.3    Sims, R.4    Gerrish, A.5
  • 54
    • 60549083544 scopus 로고    scopus 로고
    • An open access database of genome-wide association results
    • Johnson AD, O'Donnell CJ (2009) An open access database of genome-wide association results. BMC Med Genet 10: 6.
    • (2009) BMC Med Genet , vol.10 , pp. 6
    • Johnson, A.D.1    O'Donnell, C.J.2
  • 55
    • 33748672451 scopus 로고    scopus 로고
    • SNPeffect v2.0: A new step in investigating the molecular phenotypic effects of human nonsynonymous SNPs
    • Reumers J, Maurer-Stroh S, Schymkowitz J, Rousseau F (2006) SNPeffect v2.0: a new step in investigating the molecular phenotypic effects of human nonsynonymous SNPs. Bioinformatics 22: 2183-2185.
    • (2006) Bioinformatics , vol.22 , pp. 2183-2185
    • Reumers, J.1    Maurer-Stroh, S.2    Schymkowitz, J.3    Rousseau, F.4
  • 56
    • 33747871385 scopus 로고    scopus 로고
    • SNP Function Portal: A web database for exploring the function implication of SNP alleles
    • Wang P, Dai M, Xuan W, McEachin RC, Jackson AU, et al. (2006) SNP Function Portal: a web database for exploring the function implication of SNP alleles. Bioinformatics 22: e523-529.
    • (2006) Bioinformatics , vol.22
    • Wang, P.1    Dai, M.2    Xuan, W.3    McEachin, R.C.4    Jackson, A.U.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.