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Volumn 54, Issue 2, 2011, Pages 459-468

The role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathy

Author keywords

Diabetic retinopathy; Inflammation; LRP; Oxidation; Peroxidation; Retina; WNT

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; 7 OXOCHOLESTEROL; ACETYLCYSTEINE; BETA CATENIN; CONNECTIVE TISSUE GROWTH FACTOR; HYDROGEN PEROXIDE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; T CELL FACTOR PROTEIN; WNT PROTEIN;

EID: 78951469821     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1943-1     Document Type: Article
Times cited : (71)

References (49)
  • 1
    • 70349236876 scopus 로고    scopus 로고
    • Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders
    • 1:CAS:528:DC%2BD1MXhtFynsbrN 10.1016/j.exger.2009.07.003 19622391
    • MP Mattson 2009 Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders Exp Gerontol 44 625 633 1:CAS:528:DC%2BD1MXhtFynsbrN 10.1016/j.exger.2009.07.003 19622391
    • (2009) Exp Gerontol , vol.44 , pp. 625-633
    • Mattson, M.P.1
  • 2
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • 1:CAS:528:DyaK3MXmsFSnsbo%3D 10.1016/0891-5849(91)90192-6 1937131
    • H Esterbauer RJ Schaur H Zollner 1991 Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes Free Radic Biol Med 11 81 128 1:CAS:528:DyaK3MXmsFSnsbo%3D 10.1016/0891-5849(91)90192-6 1937131
    • (1991) Free Radic Biol Med , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 3
    • 45249124663 scopus 로고    scopus 로고
    • 4-Hydroxynonenal: A membrane lipid oxidation product of medicinal interest
    • 1:CAS:528:DC%2BD1cXotlWmt74%3D 10.1002/med.20117 18058921
    • G Poli RJ Schaur WG Siems G Leonarduzzi 2008 4-Hydroxynonenal: a membrane lipid oxidation product of medicinal interest Med Res Rev 28 569 631 1:CAS:528:DC%2BD1cXotlWmt74%3D 10.1002/med.20117 18058921
    • (2008) Med Res Rev , vol.28 , pp. 569-631
    • Poli, G.1    Schaur, R.J.2    Siems, W.G.3    Leonarduzzi, G.4
  • 4
    • 3242881654 scopus 로고    scopus 로고
    • Cytotoxicity of oxidized low-density lipoprotein in cultured RPE cells is dependent on the formation of 7-ketocholesterol
    • 10.1167/iovs.04-0075 15277510
    • IR Rodriguez S Alam JW Lee 2004 Cytotoxicity of oxidized low-density lipoprotein in cultured RPE cells is dependent on the formation of 7-ketocholesterol Invest Ophthalmol Vis Sci 45 2830 2837 10.1167/iovs.04-0075 15277510
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2830-2837
    • Rodriguez, I.R.1    Alam, S.2    Lee, J.W.3
  • 5
    • 0021333060 scopus 로고
    • Lipid peroxidation and retinal degeneration
    • 1:CAS:528:DyaL2cXmsF2nsQ%3D%3D 10.3109/02713688408997203 6606531
    • RE Anderson LM Rapp RD Wiegand 1984 Lipid peroxidation and retinal degeneration Curr Eye Res 3 223 227 1:CAS:528:DyaL2cXmsF2nsQ%3D%3D 10.3109/02713688408997203 6606531
    • (1984) Curr Eye Res , vol.3 , pp. 223-227
    • Anderson, R.E.1    Rapp, L.M.2    Wiegand, R.D.3
  • 6
    • 33746373850 scopus 로고    scopus 로고
    • Age-related macular degeneration (AMD): Pathogenesis and therapy
    • 1:CAS:528:DC%2BD28XhtVKrtbnO 16845209
    • JZ Nowak 2006 Age-related macular degeneration (AMD): pathogenesis and therapy Pharmacol Rep 58 353 363 1:CAS:528:DC%2BD28XhtVKrtbnO 16845209
    • (2006) Pharmacol Rep , vol.58 , pp. 353-363
    • Nowak, J.Z.1
  • 7
    • 0348048874 scopus 로고    scopus 로고
    • Diabetic retinopathy
    • 1:CAS:528:DC%2BD2cXhtFGgug%3D%3D 10.1056/NEJMra021678 14702427
    • RN Frank 2004 Diabetic retinopathy N Engl J Med 350 48 58 1:CAS:528:DC%2BD2cXhtFGgug%3D%3D 10.1056/NEJMra021678 14702427
    • (2004) N Engl J Med , vol.350 , pp. 48-58
    • Frank, R.N.1
  • 8
    • 0043133868 scopus 로고    scopus 로고
    • Changes in blood antioxidants and several lipid peroxidation products in women with age-related macular degeneration
    • 1:STN:280:DC%2BD3s3isFOhug%3D%3D 12747649
    • M Nowak E Swietochowska T Wielkoszynski, et al. 2003 Changes in blood antioxidants and several lipid peroxidation products in women with age-related macular degeneration Eur J Ophthalmol 13 281 286 1:STN:280: DC%2BD3s3isFOhug%3D%3D 12747649
    • (2003) Eur J Ophthalmol , vol.13 , pp. 281-286
    • Nowak, M.1    Swietochowska, E.2    Wielkoszynski, T.3
  • 10
    • 10044255422 scopus 로고    scopus 로고
    • Lipids and lipid peroxidation products in the pathogenesis of age-related macular degeneration
    • 1:CAS:528:DC%2BD2cXhtVKksLbE 10.1016/j.biochi.2004.09.029 15589692
    • J Kopitz FG Holz E Kaemmerer F Schutt 2004 Lipids and lipid peroxidation products in the pathogenesis of age-related macular degeneration Biochimie 86 825 831 1:CAS:528:DC%2BD2cXhtVKksLbE 10.1016/j.biochi.2004.09.029 15589692
    • (2004) Biochimie , vol.86 , pp. 825-831
    • Kopitz, J.1    Holz, F.G.2    Kaemmerer, E.3    Schutt, F.4
  • 11
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • 1:CAS:528:DyaK1cXnvFyju74%3D 10.1146/annurev.cellbio.14.1.59 9891778
    • A Wodarz R Nusse 1998 Mechanisms of Wnt signaling in development Annu Rev Cell Dev Biol 14 59 88 1:CAS:528:DyaK1cXnvFyju74%3D 10.1146/annurev.cellbio.14. 1.59 9891778
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 12
    • 60149112540 scopus 로고    scopus 로고
    • Wnt signaling in retinal development and disease
    • 10.1089/scd.2008.0169
    • N Lad S Cheshier Y Kalani 2008 Wnt signaling in retinal development and disease Stem Cells Dev 18 7 16 10.1089/scd.2008.0169
    • (2008) Stem Cells Dev , vol.18 , pp. 7-16
    • Lad, N.1    Cheshier, S.2    Kalani, Y.3
  • 13
    • 0037155691 scopus 로고    scopus 로고
    • Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
    • 1:CAS:528:DC%2BD38XisFOgs70%3D 10.1016/S0092-8674(02)00685-2 11955436
    • C Liu Y Li M Semenov, et al. 2002 Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism Cell 108 837 847 1:CAS:528:DC%2BD38XisFOgs70%3D 10.1016/S0092-8674(02)00685-2 11955436
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1    Li, Y.2    Semenov, M.3
  • 14
    • 2342430345 scopus 로고    scopus 로고
    • LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: Arrows point the way
    • 1:CAS:528:DC%2BD2cXjvVaqtbc%3D 10.1242/dev.01117 15084453
    • X He M Semenov K Tamai X Zeng 2004 LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way Development 131 1663 1677 1:CAS:528:DC%2BD2cXjvVaqtbc%3D 10.1242/dev.01117 15084453
    • (2004) Development , vol.131 , pp. 1663-1677
    • He, X.1    Semenov, M.2    Tamai, K.3    Zeng, X.4
  • 15
    • 33645816535 scopus 로고    scopus 로고
    • CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells
    • 1:CAS:528:DC%2BD28Xjs1SlsbY%3D 10.1128/MCB.26.8.2955-2964.2006 16581771
    • W Si Q Kang HH Luu, et al. 2006 CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells Mol Cell Biol 26 2955 2964 1:CAS:528:DC%2BD28Xjs1SlsbY%3D 10.1128/MCB.26.8.2955-2964.2006 16581771
    • (2006) Mol Cell Biol , vol.26 , pp. 2955-2964
    • Si, W.1    Kang, Q.2    Luu, H.H.3
  • 16
    • 73549107654 scopus 로고    scopus 로고
    • Activation of the Wnt pathway plays a pathogenic role in diabetic retinopathy in humans and animal models
    • 1:CAS:528:DC%2BC3cXktlSjsg%3D%3D 10.2353/ajpath.2009.080945 19893025
    • Y Chen Y Hu T Zhou, et al. 2009 Activation of the Wnt pathway plays a pathogenic role in diabetic retinopathy in humans and animal models Am J Pathol 175 2676 2685 1:CAS:528:DC%2BC3cXktlSjsg%3D%3D 10.2353/ajpath.2009.080945 19893025
    • (2009) Am J Pathol , vol.175 , pp. 2676-2685
    • Chen, Y.1    Hu, Y.2    Zhou, T.3
  • 17
    • 77957348383 scopus 로고    scopus 로고
    • The pathogenic role of the canonical Wnt pathway in age-related macular degeneration
    • 10.1167/iovs.09-4278 19875668
    • T Zhou Y Hu Y Chen, et al. 2009 The pathogenic role of the canonical Wnt pathway in age-related macular degeneration Invest Ophthalmol Vis Sci 51 4371 4379 10.1167/iovs.09-4278 19875668
    • (2009) Invest Ophthalmol Vis Sci , vol.51 , pp. 4371-4379
    • Zhou, T.1    Hu, Y.2    Chen, Y.3
  • 18
    • 23744481056 scopus 로고    scopus 로고
    • Glycation does not alter LDL-induced secretion of tissue plasminogen activator and plasminogen activator inhibitor-1 from human aortic endothelial cells
    • 1:CAS:528:DC%2BD2MXpvVKqtrc%3D 10.1196/annals.1333.044 16037259
    • RL Klein AJ Semler JW Baynes SR Thorpe TJ Lyons AJ Jenkins 2005 Glycation does not alter LDL-induced secretion of tissue plasminogen activator and plasminogen activator inhibitor-1 from human aortic endothelial cells Ann N Y Acad Sci 1043 379 389 1:CAS:528:DC%2BD2MXpvVKqtrc%3D 10.1196/annals.1333.044 16037259
    • (2005) Ann N y Acad Sci , vol.1043 , pp. 379-389
    • Klein, R.L.1    Semler, A.J.2    Baynes, J.W.3    Thorpe, S.R.4    Lyons, T.J.5    Jenkins, A.J.6
  • 19
    • 0026027581 scopus 로고
    • Plasminogen activator production by human retinal endothelial cells of nondiabetic and diabetic origin
    • 1:STN:280:DyaK3M7gtVWqtg%3D%3D 1702773
    • MB Grant C Guay 1991 Plasminogen activator production by human retinal endothelial cells of nondiabetic and diabetic origin Invest Ophthalmol Vis Sci 32 53 64 1:STN:280:DyaK3M7gtVWqtg%3D%3D 1702773
    • (1991) Invest Ophthalmol Vis Sci , vol.32 , pp. 53-64
    • Grant, M.B.1    Guay, C.2
  • 20
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
    • 1:CAS:528:DC%2BD3MXmt1yjt7Y%3D 10.1016/S0301-0082(01)00011-9 11527574
    • CA Grimes RS Jope 2001 The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling Prog Neurobiol 65 391 426 1:CAS:528: DC%2BD3MXmt1yjt7Y%3D 10.1016/S0301-0082(01)00011-9 11527574
    • (2001) Prog Neurobiol , vol.65 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 21
    • 33845629703 scopus 로고    scopus 로고
    • Redox regulation of 4-hydroxy-2-nonenal-mediated endothelial barrier dysfunction by focal adhesion, adherens, and tight junction proteins
    • 1:CAS:528:DC%2BD28XhtF2gur3O 10.1074/jbc.M607305200 16982627
    • PV Usatyuk NL Parinandi V Natarajan 2006 Redox regulation of 4-hydroxy-2-nonenal-mediated endothelial barrier dysfunction by focal adhesion, adherens, and tight junction proteins J Biol Chem 281 35554 35566 1:CAS:528:DC%2BD28XhtF2gur3O 10.1074/jbc.M607305200 16982627
    • (2006) J Biol Chem , vol.281 , pp. 35554-35566
    • Usatyuk, P.V.1    Parinandi, N.L.2    Natarajan, V.3
  • 22
    • 34548072307 scopus 로고    scopus 로고
    • N-Acetylcysteine-a safe antidote for cysteine/glutathione deficiency
    • 1:CAS:528:DC%2BD2sXpsFKqsrs%3D 10.1016/j.coph.2007.04.005 17602868
    • KR Atkuri JJ Mantovani LA Herzenberg 2007 N-Acetylcysteine-a safe antidote for cysteine/glutathione deficiency Curr Opin Pharmacol 7 355 359 1:CAS:528:DC%2BD2sXpsFKqsrs%3D 10.1016/j.coph.2007.04.005 17602868
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 355-359
    • Atkuri, K.R.1    Mantovani, J.J.2    Herzenberg, L.A.3
  • 23
    • 51849132576 scopus 로고    scopus 로고
    • Improved establishment of autologous stem cells derived from preantral follicle culture and oocyte parthenogenesis
    • 1:CAS:528:DC%2BD1cXhtFaisrzP 10.1089/scd.2007.0168 18752416
    • SP Gong EJ Lee ST Lee, et al. 2008 Improved establishment of autologous stem cells derived from preantral follicle culture and oocyte parthenogenesis Stem Cells Dev 17 695 712 1:CAS:528:DC%2BD1cXhtFaisrzP 10.1089/scd.2007.0168 18752416
    • (2008) Stem Cells Dev , vol.17 , pp. 695-712
    • Gong, S.P.1    Lee, E.J.2    Lee, S.T.3
  • 24
    • 47249122645 scopus 로고    scopus 로고
    • Connective tissue growth factor is necessary for retinal capillary basal lamina thickening in diabetic mice
    • 1:CAS:528:DC%2BD1cXos1Cjurw%3D 10.1369/jhc.2008.950980 18474939
    • EJ Kuiper R van Zijderveld P Roestenberg, et al. 2008 Connective tissue growth factor is necessary for retinal capillary basal lamina thickening in diabetic mice J Histochem Cytochem 56 785 792 1:CAS:528:DC%2BD1cXos1Cjurw%3D 10.1369/jhc.2008.950980 18474939
    • (2008) J Histochem Cytochem , vol.56 , pp. 785-792
    • Kuiper, E.J.1    Van Zijderveld, R.2    Roestenberg, P.3
  • 25
    • 64049116635 scopus 로고    scopus 로고
    • CTGF is increased in basal deposits and regulates matrix production through the ERK (p42/p44mapk) MAPK and the p38 MAPK signaling pathways
    • 10.1167/iovs.08-2383 19011018
    • N Nagai A Klimava WH Lee K Izumi-Nagai JT Handa 2009 CTGF is increased in basal deposits and regulates matrix production through the ERK (p42/p44mapk) MAPK and the p38 MAPK signaling pathways Invest Ophthalmol Vis Sci 50 1903 1910 10.1167/iovs.08-2383 19011018
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 1903-1910
    • Nagai, N.1    Klimava, A.2    Lee, W.H.3    Izumi-Nagai, K.4    Handa, J.T.5
  • 26
    • 47249104206 scopus 로고    scopus 로고
    • Intraretinal leakage and oxidation of LDL in diabetic retinopathy
    • 10.1167/iovs.07-1440 18362112
    • M Wu Y Chen K Wilson, et al. 2008 Intraretinal leakage and oxidation of LDL in diabetic retinopathy Invest Ophthalmol Vis Sci 49 2679 2685 10.1167/iovs.07-1440 18362112
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 2679-2685
    • Wu, M.1    Chen, Y.2    Wilson, K.3
  • 27
    • 65449157994 scopus 로고    scopus 로고
    • Effect of N-acetylcysteine on the early expression of inflammatory markers in the retina and plasma of diabetic rats
    • 10.1111/j.1442-9071.2009.02000.x 19723131
    • GY Tsai JZ Cui H Syed, et al. 2009 Effect of N-acetylcysteine on the early expression of inflammatory markers in the retina and plasma of diabetic rats Clin Experiment Ophthalmol 37 223 231 10.1111/j.1442-9071.2009.02000.x 19723131
    • (2009) Clin Experiment Ophthalmol , vol.37 , pp. 223-231
    • Tsai, G.Y.1    Cui, J.Z.2    Syed, H.3
  • 28
    • 0032422401 scopus 로고    scopus 로고
    • Immunohistochemical and ELISA assays for biomarkers of oxidative stress in aging and disease
    • 1:CAS:528:DyaK1MXjtVeitA%3D%3D 10.1111/j.1749-6632.1998.tb09909.x 9928437
    • JM Onorato SR Thorpe JW Baynes 1998 Immunohistochemical and ELISA assays for biomarkers of oxidative stress in aging and disease Ann N Y Acad Sci 854 277 290 1:CAS:528:DyaK1MXjtVeitA%3D%3D 10.1111/j.1749-6632.1998.tb09909.x 9928437
    • (1998) Ann N y Acad Sci , vol.854 , pp. 277-290
    • Onorato, J.M.1    Thorpe, S.R.2    Baynes, J.W.3
  • 29
    • 42649140551 scopus 로고    scopus 로고
    • The Wnt signaling pathway: Aging gracefully as a protectionist?
    • 1:CAS:528:DC%2BD1cXlvVSqtr4%3D 10.1016/j.pharmthera.2008.01.004 18313758
    • K Maiese F Li ZZ Chong YC Shang 2008 The Wnt signaling pathway: aging gracefully as a protectionist? Pharmacol Ther 118 58 81 1:CAS:528: DC%2BD1cXlvVSqtr4%3D 10.1016/j.pharmthera.2008.01.004 18313758
    • (2008) Pharmacol Ther , vol.118 , pp. 58-81
    • Maiese, K.1    Li, F.2    Chong, Z.Z.3    Shang, Y.C.4
  • 30
    • 36348999343 scopus 로고    scopus 로고
    • Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization
    • 1:CAS:528:DC%2BD2sXhtlSlt7%2FM 10.1074/jbc.M611289200 17890782
    • Y Chen Y Hu K Lu JG Flannery JX Ma 2007 Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization J Biol Chem 282 34420 34428 1:CAS:528:DC%2BD2sXhtlSlt7%2FM 10.1074/jbc.M611289200 17890782
    • (2007) J Biol Chem , vol.282 , pp. 34420-34428
    • Chen, Y.1    Hu, Y.2    Lu, K.3    Flannery, J.G.4    Ma, J.X.5
  • 31
    • 0042882640 scopus 로고    scopus 로고
    • Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling
    • 1:CAS:528:DC%2BD3sXlvVChtrc%3D 12833161
    • Y Yang R Sharma A Sharma S Awasthi YC Awasthi 2003 Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling Acta Biochim Pol 50 319 336 1:CAS:528:DC%2BD3sXlvVChtrc%3D 12833161
    • (2003) Acta Biochim Pol , vol.50 , pp. 319-336
    • Yang, Y.1    Sharma, R.2    Sharma, A.3    Awasthi, S.4    Awasthi, Y.C.5
  • 32
    • 77649168211 scopus 로고    scopus 로고
    • Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action
    • 10.1016/j.exer.2009.10.014 19895809
    • TU Krohne E Kaemmerer FG Holz J Kopitz 2009 Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action Exp Eye Res 90 261 266 10.1016/j.exer.2009.10.014 19895809
    • (2009) Exp Eye Res , vol.90 , pp. 261-266
    • Krohne, T.U.1    Kaemmerer, E.2    Holz, F.G.3    Kopitz, J.4
  • 33
    • 15944370026 scopus 로고    scopus 로고
    • Toxicity and detoxification of lipid-derived aldehydes in cultured retinal pigmented epithelial cells
    • 1:CAS:528:DC%2BD2MXivV2iurs%3D 10.1016/j.taap.2004.08.023 15808518
    • S Choudhary T Xiao S Srivastava, et al. 2005 Toxicity and detoxification of lipid-derived aldehydes in cultured retinal pigmented epithelial cells Toxicol Appl Pharmacol 204 122 134 1:CAS:528:DC%2BD2MXivV2iurs%3D 10.1016/j.taap.2004.08.023 15808518
    • (2005) Toxicol Appl Pharmacol , vol.204 , pp. 122-134
    • Choudhary, S.1    Xiao, T.2    Srivastava, S.3
  • 34
    • 35648929883 scopus 로고    scopus 로고
    • Gone with the Wnts: Beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism
    • 1:CAS:528:DC%2BD2sXht1ynsrbO 10.1210/me.2007-0259 17622581
    • SC Manolagas M Almeida 2007 Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism Mol Endocrinol 21 2605 2614 1:CAS:528: DC%2BD2sXht1ynsrbO 10.1210/me.2007-0259 17622581
    • (2007) Mol Endocrinol , vol.21 , pp. 2605-2614
    • Manolagas, S.C.1    Almeida, M.2
  • 35
    • 34848814178 scopus 로고    scopus 로고
    • Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription
    • 1:CAS:528:DC%2BD2sXhtVWjsb7M 10.1074/jbc.M702811200 17623658
    • M Almeida L Han M Martin-Millan CA O'Brien SC Manolagas 2007 Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription J Biol Chem 282 27298 27305 1:CAS:528:DC%2BD2sXhtVWjsb7M 10.1074/jbc.M702811200 17623658
    • (2007) J Biol Chem , vol.282 , pp. 27298-27305
    • Almeida, M.1    Han, L.2    Martin-Millan, M.3    O'Brien, C.A.4    Manolagas, S.C.5
  • 36
    • 44049092138 scopus 로고    scopus 로고
    • Interaction of FOXO with beta-catenin inhibits beta-catenin/T cell factor activity
    • 1:CAS:528:DC%2BD1cXjslyru7k%3D 10.1074/jbc.M706638200 18250171
    • D Hoogeboom MA Essers PE Polderman E Voets LM Smits BM Burgering 2008 Interaction of FOXO with beta-catenin inhibits beta-catenin/T cell factor activity J Biol Chem 283 9224 9230 1:CAS:528:DC%2BD1cXjslyru7k%3D 10.1074/jbc.M706638200 18250171
    • (2008) J Biol Chem , vol.283 , pp. 9224-9230
    • Hoogeboom, D.1    Essers, M.A.2    Polderman, P.E.3    Voets, E.4    Smits, L.M.5    Burgering, B.M.6
  • 37
    • 18844382368 scopus 로고    scopus 로고
    • Functional interaction between beta-catenin and FOXO in oxidative stress signaling
    • 1:CAS:528:DC%2BD2MXkt1Sltro%3D 10.1126/science.1109083 15905404
    • MA Essers LM de Vries-Smits N Barker PE Polderman BM Burgering HC Korswagen 2005 Functional interaction between beta-catenin and FOXO in oxidative stress signaling Science 308 1181 1184 1:CAS:528:DC%2BD2MXkt1Sltro%3D 10.1126/science.1109083 15905404
    • (2005) Science , vol.308 , pp. 1181-1184
    • Essers, M.A.1    De Vries-Smits, L.M.2    Barker, N.3    Polderman, P.E.4    Burgering, B.M.5    Korswagen, H.C.6
  • 38
    • 3242883359 scopus 로고    scopus 로고
    • Hydrogen peroxide negatively modulates Wnt signaling through downregulation of beta-catenin
    • 1:CAS:528:DC%2BD2cXlvFyqur4%3D 10.1016/j.canlet.2004.03.003 15279902
    • SY Shin CG Kim EH Jho, et al. 2004 Hydrogen peroxide negatively modulates Wnt signaling through downregulation of beta-catenin Cancer Lett 212 225 231 1:CAS:528:DC%2BD2cXlvFyqur4%3D 10.1016/j.canlet.2004.03.003 15279902
    • (2004) Cancer Lett , vol.212 , pp. 225-231
    • Shin, S.Y.1    Kim, C.G.2    Jho, E.H.3
  • 39
    • 33646858497 scopus 로고    scopus 로고
    • The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled
    • 1:CAS:528:DC%2BD28XksVGnurc%3D 10.1038/ncb1405 16604061
    • Y Funato T Michiue M Asashima H Miki 2006 The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled Nat Cell Biol 8 501 508 1:CAS:528:DC%2BD28XksVGnurc%3D 10.1038/ncb1405 16604061
    • (2006) Nat Cell Biol , vol.8 , pp. 501-508
    • Funato, Y.1    Michiue, T.2    Asashima, M.3    Miki, H.4
  • 40
    • 2642538349 scopus 로고    scopus 로고
    • Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells
    • 1:CAS:528:DC%2BD2cXkvFOkur0%3D 10.1111/j.1471-4159.2004.02413.x 15147515
    • B Dozza MA Smith G Perry M Tabaton P Strocchi 2004 Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells J Neurochem 89 1224 1232 1:CAS:528:DC%2BD2cXkvFOkur0%3D 10.1111/j.1471-4159.2004.02413.x 15147515
    • (2004) J Neurochem , vol.89 , pp. 1224-1232
    • Dozza, B.1    Smith, M.A.2    Perry, G.3    Tabaton, M.4    Strocchi, P.5
  • 41
    • 0344464720 scopus 로고    scopus 로고
    • Wnts and Hedgehogs: Lipid-modified proteins and similarities in signaling mechanisms at the cell surface
    • 1:CAS:528:DC%2BD3sXps12qtro%3D 10.1242/dev.00821 14530294
    • R Nusse 2003 Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface Development 130 5297 5305 1:CAS:528:DC%2BD3sXps12qtro%3D 10.1242/dev.00821 14530294
    • (2003) Development , vol.130 , pp. 5297-5305
    • Nusse, R.1
  • 42
    • 0034727104 scopus 로고    scopus 로고
    • LDL-receptor-related proteins in Wnt signal transduction
    • 1:STN:280:DC%2BD3cvnslKgtQ%3D%3D 10.1038/35035117 11029007
    • K Tamai M Semenov Y Kato, et al. 2000 LDL-receptor-related proteins in Wnt signal transduction Nature 407 530 535 1:STN:280:DC%2BD3cvnslKgtQ%3D%3D 10.1038/35035117 11029007
    • (2000) Nature , vol.407 , pp. 530-535
    • Tamai, K.1    Semenov, M.2    Kato, Y.3
  • 43
    • 0037737726 scopus 로고    scopus 로고
    • Wnt proteins are lipid-modified and can act as stem cell growth factors
    • 1:CAS:528:DC%2BD3sXjvFalt7c%3D 10.1038/nature01611 12717451
    • K Willert JD Brown E Danenberg, et al. 2003 Wnt proteins are lipid-modified and can act as stem cell growth factors Nature 423 448 452 1:CAS:528:DC%2BD3sXjvFalt7c%3D 10.1038/nature01611 12717451
    • (2003) Nature , vol.423 , pp. 448-452
    • Willert, K.1    Brown, J.D.2    Danenberg, E.3
  • 44
    • 0030977793 scopus 로고    scopus 로고
    • Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein
    • 1:CAS:528:DyaK2sXhvFWgs7g%3D 10.1016/S0014-5793(97)00148-8 9094417
    • B Friguet LI Szweda 1997 Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein FEBS Lett 405 21 25 1:CAS:528:DyaK2sXhvFWgs7g%3D 10.1016/S0014-5793(97)00148-8 9094417
    • (1997) FEBS Lett , vol.405 , pp. 21-25
    • Friguet, B.1    Szweda, L.I.2
  • 45
    • 0033588087 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules
    • 1:CAS:528:DyaK1MXlsVOnsLg%3D 10.1074/jbc.274.34.23787 10446139
    • K Okada C Wangpoengtrakul T Osawa S Toyokuni K Tanaka K Uchida 1999 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules J Biol Chem 274 23787 23793 1:CAS:528:DyaK1MXlsVOnsLg%3D 10.1074/jbc.274.34.23787 10446139
    • (1999) J Biol Chem , vol.274 , pp. 23787-23793
    • Okada, K.1    Wangpoengtrakul, C.2    Osawa, T.3    Toyokuni, S.4    Tanaka, K.5    Uchida, K.6
  • 46
    • 0442307849 scopus 로고    scopus 로고
    • 4-Hydroxynonenal oxidatively modifies histones: Implications for Alzheimer's disease
    • 1:CAS:528:DC%2BD2cXhtFCisL8%3D 10.1016/j.neulet.2003.11.047 15036618
    • J Drake R Petroze A Castegna, et al. 2004 4-Hydroxynonenal oxidatively modifies histones: implications for Alzheimer's disease Neurosci Lett 356 155 158 1:CAS:528:DC%2BD2cXhtFCisL8%3D 10.1016/j.neulet.2003.11.047 15036618
    • (2004) Neurosci Lett , vol.356 , pp. 155-158
    • Drake, J.1    Petroze, R.2    Castegna, A.3
  • 48
    • 38949194936 scopus 로고    scopus 로고
    • Initiation of Wnt signaling: Control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
    • 1:CAS:528:DC%2BD1cXitVShu7Y%3D 10.1242/dev.013540 18077588
    • X Zeng H Huang K Tamai, et al. 2008 Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions Development 135 367 375 1:CAS:528:DC%2BD1cXitVShu7Y%3D 10.1242/dev.013540 18077588
    • (2008) Development , vol.135 , pp. 367-375
    • Zeng, X.1    Huang, H.2    Tamai, K.3
  • 49
    • 51149123490 scopus 로고    scopus 로고
    • Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation
    • 1:CAS:528:DC%2BD1cXhtVGkurvM 10.1126/science.1160741 18772438
    • W Pan SC Choi H Wang, et al. 2008 Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation Science 321 1350 1353 1:CAS:528:DC%2BD1cXhtVGkurvM 10.1126/science.1160741 18772438
    • (2008) Science , vol.321 , pp. 1350-1353
    • Pan, W.1    Choi, S.C.2    Wang, H.3


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