Molecular mechanisms of glucocorticoids action: Implications for treatment of rhinosinusitis and nasal polyposis

European Archives of Oto-Rhino-Laryngology

Volumn 268, Issue 2, 2011, Pages 247-253

  Grzanka, Alicja ^a   Misiołek, MacIej ^a   Golusiński, Wojciech ^b   Jarza̧b, Jerzy ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Glucocorticoids; Nasal polyps; Nongenomic and genomic action; Rhinitis

Indexed keywords

BETAMETHASONE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; METHYLPREDNISOLONE; PROTEIN KINASE C; VASCULOTROPIN;

ARTICLE; CELL MEMBRANE; CYTOPLASM; DRUG ACTIVITY; DRUG EFFICACY; GENE EXPRESSION; HUMAN; MICROARRAY ANALYSIS; NOSE POLYP; PRIORITY JOURNAL; RHINOSINUSITIS;

ADMINISTRATION, INTRANASAL; GLUCOCORTICOIDS; HUMANS; NASAL POLYPS; RECEPTORS, GLUCOCORTICOID; RHINITIS; SINUSITIS; TRANSCRIPTION, GENETIC;

EID: 78751566749     PISSN: 09374477     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00405-010-1330-z     Document Type: Article

References (43)

1. P Schalek L Otruba A Hahn 2010 Quality of life in patients with chronic rhinosinusitis: a validation of the Czech version of SNOT-22 questionnaire Eur Arch Otorhinolaryngol 267 473 475 10.1007/s00405-009-1180-8 20033700
2. Z Dudvarski I Pendjer V Djukic L Janosevic A Mikic 2008 The analysis of clinical characteristics of the chronic rhinosinusitis: complicated and uncomplicated form Eur Arch Otorhinolaryngol 265 923 927 10.1007/s00405-008- 0587-y 18247038
3. GK Scadding SR Durham R Mirakian, et al. 2008 BSACI guidelines for the management of rhinosinusitis and nasal polyposis Clin Exp Allergy 38 2 260 275 1:CAS:528:DC%2BD1cXjtFalsb0%3D 10.1111/j.1365-2222.2007.02889.x 18167126
4. M Thomas B Yawn D Price, et al. 2008 EPOS primary care guidelines: European position paper on the primary care diagnosis and management of rhinosinusitis and nasal polyps 2007 - a summary Prim Care Resp J 17 2 79 89 10.3132/pcrj.2008.00029
5. DV Wallace MS Dykewicz DI Bernstein, et al. 2008 The diagnosis and management of rhinitis: an updated practice parameter J Allergy Clin Immunol 122 1 84 10.1016/j.jaci.2008.06.003
6. J Bousquet N Khaltaev AA Cruz, et al. 2008 Allergic rhinitis and its impact on asthma (ARIA) 2008 update Allergy 63 8 160 10.1111/j.1398-9995.2007. 01620.x 18331513
7. H Shirasaki K Watanabe E Kanaizumi N Konno J Sato S Narita T Himi 2004 Expression and localization of steroid receptors in human nasal mucosa Acta Otolaryngol 124 8 958 963 1:CAS:528:DC%2BD2cXnvVOnsr4%3D 10.1080/ 00016480310017063 15536653
8. DY Leung JW Bloom 2003 Update on glucocorticoid action and resistance J Allergy Clin Immunol 111 3 22 1:CAS:528:DC%2BD3sXht1Wrsbc%3D 10.1067/mai.2003.97 12532089
9. L Pujols J Mullol A Torrego C Picado 2004 Glucocorticoid receptors in human airways Allergy 59 1042 1052 1:CAS:528:DC%2BD2cXptlKqsbY%3D 10.1111/j.1398-9995.2004.00635.x 15355461
10. L Pujols J Mullol C Picado 2007 Alpha and beta glucocorticoid receptors: relevance in airway diseases Curr Allergy Asthma Rep 7 93 99 1:CAS:528:DC%2BD2sXpt1GrtLk%3D 10.1007/s11882-007-0005-3 17437678
11. L Pujols I Alobid P Benitez A Martinez-Antón J Roca-Ferrer WJ Fokkens J Mullol C Picado 2008 Regulation of glucocorticoid receptor in nasal polyps by systemic and intranasal glucocorticoids Allergy 63 1377 1386 1:STN:280:DC%2BD1crpt1yjtQ%3D%3D 10.1111/j.1398-9995.2008.01745.x 18671773
12. P Stjärne R Mösges M Jorissen D Passàli L Bellussi H Staudinger M Danzig 2006 A randomized controlled trial of mometasone furoate nasal spray for the treatment of nasal polyposis Arch Otolaryngol Head Neck Surg 132 2 179 185 10.1001/archotol.132.2.179 16490876
13. D Duma CM Jewell JA Cidlowski 2006 Multiple glucocorticoid receptor isoforms and mechanisms of post-translational modification J Steroid Biochem Mol Biol 102 11 21 1:CAS:528:DC%2BD28Xht1Cmt7bO 10.1016/j.jsbmb.2006.09.009 17070034
14. B Bartholome CM Spies T Gaber, et al. 2004 Membrane glucocorticoid receptors (mGCR) are expressed in normal peripheral blood mononuclear cells and upregulated following in vitro stimulation and in patients with rheumatoid arthritis FASEB J 18 70 80 1:CAS:528:DC%2BD2cXmt1Knsw%3D%3D 10.1096/fj.03- 0328com 14718388
15. PJ Barnes 2006 How corticosteroids control inflammation: quintiles prize lecture 2005 Br J Pharmacol 148 245 254 1:CAS:528:DC%2BD28XltVCjt74%3D 10.1038/sj.bjp.0706736 16604091
16. K Ito KF Chung IM Adcock 2006 Update on glucocorticoid action and resistance J Allergy Clin Immunol 117 522 543 1:CAS:528:DC%2BD28Xit1aqt7s%3D 10.1016/j.jaci.2006.01.032 16522450
17. C Stellato 2004 Post-transcriptional and nongenomic effects of glucocorticoids Proc Am Thorac Soc 1 255 263 10.1513/pats.200402-015MS 16113443
18. M Benson L Carlsson M Adner M Jernås M Rudemo A Sjögren PA Svensson R Uddman LO Cardell 2004 Gene profiling reveals increased expression of uteroglobin and other anti-inflammatory genes in glucocorticoid-treated nasal polyps J Allergy Clin Immunol 113 1137 1143 1:CAS:528:DC%2BD2cXltVOitLg%3D 10.1016/j.jaci.2004.02.028 15208596
19. AA George RL Schiltz GL Hager 2009 Dynamic access of the glucocorticoid receptor to response elements in chromatin Int J Biochem Cell Biol 41 214 224 1:CAS:528:DC%2BD1cXhsVWnu7zL 10.1016/j.biocel.2008.09.019 18930837
20. V Urbach V Verriere Y Grumbach J Bousquet BJ Harvey 2006 Rapid anti-secretory effects of glucocorticoids in human airway epithelium Steroids 71 323 328 1:CAS:528:DC%2BD28XjtFOrsLk%3D 10.1016/j.steroids.2005.09.014 16298406
21. + exchanger activity in human bronchial epithelial cells J Biol Chem 280 35807 35814 1:CAS:528:DC%2BD2MXhtFCjsbbJ 10.1074/jbc.M506584200 16040608
22. G Horvath S Vasas A Wanner 2007 Inhaled corticosteroids reduce asthma-associated airway hyperperfusion through genomic and nongenomic mechanisms Pulm Pharmacol Ther 20 2 157 162 1:CAS:528:DC%2BD28Xht1eqtLbM 10.1016/j.pupt.2006.03.009 16765074
23. JD Croxtall Q Choudhury RJ Flower 2000 Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism Br J Pharmacol 130 289 298 1:CAS:528:DC%2BD3cXjsl2mtbk%3D 10.1038/sj.bjp.0703272 10807665
24. L Liu YX Wang J Zhou F Long HW Sun Y Liu YZ Chen CL Jiang 2005 Rapid non-genomic inhibitory effects of glucocorticoids on human neutrophil degranulation Inflamm Res 54 1 37 41 1:CAS:528:DC%2BD2MXkvVWrtrs%3D 10.1007/s00011-004-1320-y 15723203
25. F Long YX Wang L Liu J Zhou RY Cui CL Jiang 2005 Rapid nongenomic inhibitory effects of glucocorticoids on phagocytosis and superoxide anion production by macrophages Steroids 70 55 61 1:CAS:528:DC%2BD2cXhtFahs7jN 10.1016/j.steroids.2004.10.004 15610897
26. M Löwenberg C Stan DW Holmes F Buttgereit 2008 Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands Steroids 73 1025 1029 10.1016/j.steroids.2007.12.002 18221974
27. - secretion by dexamethasone in human bronchial epithelium J Physiol 545 869 878 1:CAS:528:DC%2BD3sXpvV2kuw%3D%3D 10.1113/jphysiol.2002.028183 12482892
28. JM Bernstein J Gorfien B Noble JR Yankaskas 1997 Nasal polyposis: immunohistochemistry and bioelectrical findings (a hypothesis for the development of nasal polyps) J Allergy Clin Immunol 99 165 175 1:STN:280:DyaK2s7psVKjsA%3D%3D 10.1016/S0091-6749(97)70091-5 9042040
29. HC Tillmann BA Stuck M Feuring K Rossol-Haseroth BM Tran R Lösel BM Schmidt K Hörmann M Wehling A Schultz 2004 Delayed genomic and acute nongenomic action of glucocorticosteroids in seasonal allergic rhinitis Eur J Clin Invest 34 67 73 1:CAS:528:DC%2BD2cXhvFeis7s%3D 10.1111/j.1365-2362.2004. 01293.x 14984440
30. F Buttgereit JA Silva M Boers GR Burmester M Cutolo J Jacobs J Kirwan L Köhler P Van Riel T Vischer JW Bijlsma 2002 Standardised nomenclature for glucocorticoid dosages and glucocorticoid treatment regimens: current questions and tentative answers in rheumatology Ann Rheum Dis 61 718 722 1:CAS:528:DC%2BD38XmsVajuro%3D 10.1136/ard.61.8.718 12117678
31. J Haller G Makara E Mikics 2008 The effects of nongenomic glucocorticoid mechanisms on bodily functions and the central neural system. A critical evaluation of findings Front Neuroendocrinol 29 273 291 1:CAS:528: DC%2BD1cXksVeiuro%3D 10.1016/j.yfrne.2007.10.004 18054070
32. M Salter K Biggadike JL Matthews, et al. 2007 Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease Am J Physiol Lung Cell Mol Physiol 293 3 660 667 10.1152/ajplung.00108.2007
33. M Issar S Sahasranaman P Buchwald G Hochhaus 2006 Differences in the glucocorticoid to progesterone receptor selectivity of inhaled glucocorticoids Eur Respir J 27 3 511 516 1:CAS:528:DC%2BD28XjtVKqtb0%3D 10.1183/09031936.06. 00060005 16507850
34. J Newton K Wong Ah-See 2008 A review of nasal polyposis Ther Clin Risk Manag 4 2 507 512 18728843
35. HS Lee A Myers J Kim 2009 Vascular endothelial growth factor drives autocrine epithelial cell proliferation and survival in chronic rhinosinusitis with nasal polyposis Am J Respir Crit Care Med 180 1056 1067 1:CAS:528:DC%2BD1MXhsFynu7zF 10.1164/rccm.200905-0740OC 19762561
36. S Psarras E Volonaki CL Skevaki M Xatzipsalti A Bossios H Pratsinis S Tsigkos D Gourgiotis AG Constantopoulos A Papapetropoulos P Saxoni-Papageorgiou NG Papadopoulos 2006 Vascular endothelial growth factor-mediated induction of angiogenesis by human rhinoviruses J Allergy Clin Immunol 117 291 297 1:CAS:528:DC%2BD28XhtlCktL4%3D 10.1016/j.jaci.2005.11.005 16461129
37. U Pipkorn T Berge 1983 Long-term treatment with budesonide in vasomotor rhinitis Acta Otolaryngol 95 167 171 1:STN:280:DyaL3s7kvFShtw%3D%3D 10.3109/00016488309130931 6829298
38. DR Webb EO Meltzer AF Finn Jr KA Rickard PJ Pepsin R Westlund CK Cook 2002 Intranasal fluticasone propionate is effective for perennial nonallergic rhinitis with or without eosinophilia Ann Allergy Asthma Immunol 88 4 385 390 1:CAS:528:DC%2BD38XjslKitb0%3D 10.1016/S1081-1206(10)62369-1 11995670
39. H Hallen J Enerdal P Graf 1997 Fluticasone propionate nasal spray is more effective and has a faster onset of action than placebo in treatment of rhinitis medicamentosa Clin Exp Allergy 27 552 558 1:CAS:528:DyaK2sXjvF2itb4%3D 10.1111/j.1365-2222.1997.tb00744.x 9179430
40. EO Meltzer F Caballero LM Fromer JH Krouse G Scadding 2010 Treatment of congestion in upper respiratory diseases Int J Gen Med 3 69 91 1:CAS:528:DC%2BC3cXjtVKitLg%3D 20463825
41. RA Settipane DR Charnock 2007 Epidemiology of rhinitis: allergic and nonallergic Clin Allergy Immunol 19 23 34 17153005
42. LH Kalish G Arendts R Sack JC Craig 2009 Topical steroids in chronic rhinosinusitis without polyps: a systematic review and meta-analysis Otolaryngol Head Neck Surg 141 6 674 683 10.1016/j.otohns.2009.08.006 19932837
43. Cingi C, Songu M (2009) Nasal steroid perspective: knowledge and attitudes. Eur Arch Otorhinolaryngol. doi: 10.1007/s00405-009-1159-5