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Volumn 43, Issue 2, 2011, Pages 265-270

Wnt signaling and hepatocarcinogenesis: The hepatoblastoma model

Author keywords

Catenin; Classification; Hepatoblastoma; Liver; Wnt

Indexed keywords

BETA CATENIN; MUTANT PROTEIN; WNT PROTEIN;

EID: 78651424156     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2009.07.012     Document Type: Article
Times cited : (96)

References (70)
  • 1
    • 67349252606 scopus 로고    scopus 로고
    • Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastomaand global deregulation in cell growth and survival pathways
    • Adesina AM, Lopez-Terrada D, Wong KK, Gunaratne P, Nguyen Y, Pulliam J, et al. Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastomaand global deregulation in cell growth and survival pathways. Hum Pathol 2009;40:843-53.
    • (2009) Hum Pathol , vol.40 , pp. 843-853
    • Adesina, A.M.1    Lopez-Terrada, D.2    Wong, K.K.3    Gunaratne, P.4    Nguyen, Y.5    Pulliam, J.6
  • 3
    • 34347385893 scopus 로고    scopus 로고
    • Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations
    • Audard V, Grimber G, Elie C, Radenen B, Audebourg A, Letourneur F, et al. Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations. J Pathol 2007;212:345-52.
    • (2007) J Pathol , vol.212 , pp. 345-352
    • Audard, V.1    Grimber, G.2    Elie, C.3    Radenen, B.4    Audebourg, A.5    Letourneur, F.6
  • 5
    • 33846463379 scopus 로고    scopus 로고
    • Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
    • Boyault S, Rickman DS, de Reynies A, Balabaud C, Rebouissou S, Jeannot E, et al. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology 2007;45:42-52.
    • (2007) Hepatology , vol.45 , pp. 42-52
    • Boyault, S.1    Rickman, D.S.2    De Reynies, A.3    Balabaud, C.4    Rebouissou, S.5    Jeannot, E.6
  • 6
    • 33750536032 scopus 로고    scopus 로고
    • Differential gene expression in periportal and perivenous mouse hepatocytes
    • Braeuning A, Ittrich C, Kohle C, Hailfinger S, Bonin M, Buchmann A, et al. Differential gene expression in periportal and perivenous mouse hepatocytes. FEBS J 2006;273:5051-61.
    • (2006) FEBS J , vol.273 , pp. 5051-5061
    • Braeuning, A.1    Ittrich, C.2    Kohle, C.3    Hailfinger, S.4    Bonin, M.5    Buchmann, A.6
  • 7
    • 0033867475 scopus 로고    scopus 로고
    • Genetics of Hepatocellular Carcinoma
    • Buendia MA. Genetics of Hepatocellular Carcinoma. Semin Cancer Biol 2000;10: 185-200.
    • (2000) Semin Cancer Biol , vol.10 , pp. 185-200
    • Buendia, M.A.1
  • 8
    • 0036836623 scopus 로고    scopus 로고
    • Genetic alterations in hepatoblastoma and hepatocellular carcinoma: Common and distinctive aspects
    • Buendia MA. Genetic alterations in hepatoblastoma and hepatocellular carcinoma: common and distinctive aspects. Med Pediatr Oncol 2002;39:530-5.
    • (2002) Med Pediatr Oncol , vol.39 , pp. 530-535
    • Buendia, M.A.1
  • 9
    • 66449086571 scopus 로고    scopus 로고
    • Liver zonation occurs through a beta-catenin-dependent, c-Myc-independent mechanism
    • e1-3
    • Burke ZD, Reed KR, Phesse TJ, Sansom OJ, Clarke AR, Tosh D. Liver zonation occurs through a beta-catenin-dependent, c-Myc-independent mechanism. Gastroenterology 2009;136, 2316-24 e1-3.
    • (2009) Gastroenterology , vol.136 , pp. 2316-2324
    • Burke, Z.D.1    Reed, K.R.2    Phesse, T.J.3    Sansom, O.J.4    Clarke, A.R.5    Tosh, D.6
  • 11
    • 0037191930 scopus 로고    scopus 로고
    • New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism
    • Cadoret A, Ovejero C, Terris B, Souil E, Levy L, Lamers WH, et al. New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism. Oncogene 2002;21:8293-301.
    • (2002) Oncogene , vol.21 , pp. 8293-8301
    • Cadoret, A.1    Ovejero, C.2    Terris, B.3    Souil, E.4    Levy, L.5    Lamers, W.H.6
  • 12
    • 57049182539 scopus 로고    scopus 로고
    • Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer
    • Cairo S, Armengol C, De Reynies A, Wei Y, Thomas E, Renard CA, et al. Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer. Cancer Cell 2008;14: 471-84.
    • (2008) Cancer Cell , vol.14 , pp. 471-484
    • Cairo, S.1    Armengol, C.2    De Reynies, A.3    Wei, Y.4    Thomas, E.5    Renard, C.A.6
  • 13
    • 33746504789 scopus 로고    scopus 로고
    • Hepatoblastomas and liver development: A study of cytokeratin immunoexpression in twenty-nine hepatoblastomas
    • Cajaiba MM, Neves JI, Casarotti FF, de Camargo B, ChapChap P, Sredni ST, et al. Hepatoblastomas and liver development: a study of cytokeratin immunoexpression in twenty-nine hepatoblastomas. Pediatr Dev Pathol 2006;9: 196-202.
    • (2006) Pediatr Dev Pathol , vol.9 , pp. 196-202
    • Cajaiba, M.M.1    Neves, J.I.2    Casarotti, F.F.3    De Camargo, B.4    Chapchap, P.5    Sredni, S.T.6
  • 14
    • 55249106920 scopus 로고    scopus 로고
    • Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology
    • Cavard C, Colnot S, Audard V, Benhamouche S, Finzi L, Torre C, et al. Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology. Future Oncol 2008;4:647-60.
    • (2008) Future Oncol , vol.4 , pp. 647-660
    • Cavard, C.1    Colnot, S.2    Audard, V.3    Benhamouche, S.4    Finzi, L.5    Torre, C.6
  • 15
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006;127:469-80.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 16
    • 33745601104 scopus 로고    scopus 로고
    • Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages
    • 2-7
    • DanYY, Riehle KJ, LazaroC, Teoh N,Haque J,Campbell JS, et al. Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages. Proc Natl Acad Sci USA 2006;103:9912-7.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 991
    • Dan, Y.Y.1    Riehle, K.J.2    Lazaro, C.3    Teoh, N.4    Haque, J.5    Campbell, J.S.6
  • 17
    • 0345006147 scopus 로고    scopus 로고
    • Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
    • de La Coste A, Romagnolo B, Billuart P, Renard CA, Buendia MA, Soubrane O, et al. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci USA 1998;95:8847-51.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8847-8851
    • De La Coste, A.1    Romagnolo, B.2    Billuart, P.3    Renard, C.A.4    Ma, B.5    Soubrane, O.6
  • 18
    • 38649093310 scopus 로고    scopus 로고
    • Stabilization of beta-catenin affectsmouse embryonic liver growth and hepatoblast fate
    • Decaens T, Godard C, de Reynies A, Rickman DS, Tronche F, Couty JP, et al. Stabilization of beta-catenin affectsmouse embryonic liver growth and hepatoblast fate. Hepatology 2008;47:247-58.
    • (2008) Hepatology , vol.47 , pp. 247-258
    • Decaens, T.1    Godard, C.2    De Reynies, A.3    Rickman, D.S.4    Tronche, F.5    Couty, J.P.6
  • 19
    • 14244254732 scopus 로고    scopus 로고
    • Hepatic tumors in childhood: Experience on 245 tumors and review of literature
    • Fabre M, Yilmaz F, Buendia MA. Hepatic tumors in childhood: experience on 245 tumors and review of literature. Ann Pathol 2004;24:536-55.
    • (2004) Ann Pathol , vol.24 , pp. 536-55
    • Fabre, M.1    Yilmaz, F.2    Buendia, M.A.3
  • 21
    • 20444457518 scopus 로고    scopus 로고
    • Microarray analysis identifies a death-fromcancer signature predicting therapy failure in patients with multiple types of cancer
    • Glinsky GV, Berezovska O, Glinskii AB. Microarray analysis identifies a death-fromcancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest 2005;115:1503-21.
    • (2005) J Clin Invest , vol.115 , pp. 1503-1521
    • Glinsky, G.V.1    Berezovska, O.2    Glinskii, A.B.3
  • 22
    • 47649084257 scopus 로고    scopus 로고
    • APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development
    • Goessling W, North TE, Lord AM, Ceol C, Lee S, Weidinger G, et al. APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Dev Biol 2008;320:161-74.
    • (2008) Dev Biol , vol.320 , pp. 161-174
    • Goessling, W.1    North, T.E.2    Lord, A.M.3    Ceol, C.4    Lee, S.5    Weidinger, G.6
  • 23
    • 34447137342 scopus 로고    scopus 로고
    • Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC
    • Goga A, Yang D, Tward AD, Morgan DO, Bishop JM. Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC. Nat Med 2007;13:820-7.
    • (2007) Nat Med , vol.13 , pp. 820-827
    • Goga, A.1    Yang, D.2    Tward, A.D.3    Morgan, D.O.4    Bishop, J.M.5
  • 25
    • 62549118631 scopus 로고    scopus 로고
    • Wnt signaling, lgr5, and stem cells in the intestine and skin
    • Haegebarth A, Clevers H. Wnt signaling, lgr5, and stem cells in the intestine and skin. Am J Pathol 2009;174:715-21.
    • (2009) Am J Pathol , vol.174 , pp. 715-721
    • Haegebarth, A.1    Clevers, H.2
  • 27
    • 33646128218 scopus 로고    scopus 로고
    • Claudin-1 and claudin-2 differentiate fetal and embryonal components in human hepatoblastoma
    • Halasz J, Holczbauer A, Paska C, Kovacs M, Benyo G, Verebely T, et al. Claudin-1 and claudin-2 differentiate fetal and embryonal components in human hepatoblastoma. Hum Pathol 2006;37:555-61.
    • (2006) Hum Pathol , vol.37 , pp. 555-561
    • Halasz, J.1    Holczbauer, A.2    Paska, C.3    Kovacs, M.4    Benyo, G.5    Verebely, T.6
  • 28
    • 23944461569 scopus 로고    scopus 로고
    • The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds
    • Hirschman BA, Pollock BH, Tomlinson GE. The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds. J Pediatr 2005;147:263-6.
    • (2005) J Pediatr , vol.147 , pp. 263-266
    • Hirschman, B.A.1    Pollock, B.H.2    Tomlinson, G.E.3
  • 29
    • 35648940341 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells
    • Hu M, Kurobe M, Jeong YJ, Fuerer C, Ghole S, Nusse R, et al. Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells. Gastroenterology 2007;133:1579-91.
    • (2007) Gastroenterology , vol.133 , pp. 1579-1591
    • Hu, M.1    Kurobe, M.2    Jeong, Y.J.3    Fuerer, C.4    Ghole, S.5    Nusse, R.6
  • 30
    • 0031757172 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 and cdk4 in tumorigenesis of sporadic hepatoblastomas
    • Kim H, Ham EK, Kim YI, Chi JG, Lee HS, Park SH, et al. Overexpression of cyclin D1 and cdk4 in tumorigenesis of sporadic hepatoblastomas. Cancer Lett 1998;131:177-83.
    • (1998) Cancer Lett , vol.131 , pp. 177-183
    • Kim, H.1    Ham, E.K.2    Kim, Y.I.3    Chi, J.G.4    Lee, H.S.5    Park, S.H.6
  • 31
    • 33748850636 scopus 로고    scopus 로고
    • Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
    • Kirstetter P, Anderson K, Porse BT, Jacobsen SE, Nerlov C. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat Immunol 2006;7: 1048-56.
    • (2006) Nat Immunol , vol.7 , pp. 1048-1056
    • Kirstetter, P.1    Anderson, K.2    Porse, B.T.3    Jacobsen, S.E.4    Nerlov, C.5
  • 32
    • 0033556426 scopus 로고    scopus 로고
    • Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the b-catenin gene
    • Koch A, Denkhaus D, Albrecht S, Leuschner I, von Schweinitz D, Pietsch T. Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the b-catenin gene. Cancer Res 1999;59:269-73.
    • (1999) Cancer Res , vol.59 , pp. 269-273
    • Koch, A.1    Denkhaus, D.2    Albrecht, S.3    Leuschner, I.4    Von Schweinitz, D.5    Pietsch, T.6
  • 33
    • 0031848068 scopus 로고    scopus 로고
    • Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
    • Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, et al. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet 1998;19:379-83.
    • (1998) Nat Genet , vol.19 , pp. 379-383
    • Korinek, V.1    Barker, N.2    Moerer, P.3    Van Donselaar, E.4    Huls, G.5    Peters, P.J.6
  • 34
    • 67349272856 scopus 로고    scopus 로고
    • Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors
    • Lopez-Terrada D, Gunaratne PH, Adesina AM, Pulliam J, Hoang DM, Nguyen Y, et al. Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors. Hum Pathol 2009;40:783-94.
    • (2009) Hum Pathol , vol.40 , pp. 783-794
    • Lopez-Terrada, D.1    Gunaratne, P.H.2    Adesina, A.M.3    Pulliam, J.4    Hoang, D.M.5    Nguyen, Y.6
  • 35
    • 22344441322 scopus 로고    scopus 로고
    • Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells
    • Lowry WE, Blanpain C, Nowak JA, Guasch G, Lewis L, Fuchs E. Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev 2005;19:1596-611.
    • (2005) Genes Dev , vol.19 , pp. 1596-1611
    • Lowry, W.E.1    Blanpain, C.2    Nowak, J.A.3    Guasch, G.4    Lewis, L.5    Fuchs, E.6
  • 36
    • 33750613935 scopus 로고    scopus 로고
    • Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas
    • Luo JH, Ren B, Keryanov S, Tseng GC, Rao UN, Monga SP, et al. Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas. Hepatology 2006;44:1012-24.
    • (2006) Hepatology , vol.44 , pp. 1012-1024
    • Luo, J.H.1    Ren, B.2    Keryanov, S.3    Tseng, G.C.4    Rao, U.N.5    Monga, S.P.6
  • 37
    • 33747053437 scopus 로고    scopus 로고
    • Early temporal-specific responses and differential sensitivity to lithium and Wnt-3A exposure during heart development
    • Manisastry SM, Han M, Linask KK. Early temporal-specific responses and differential sensitivity to lithium and Wnt-3A exposure during heart development. Dev Dyn 2006;235:2160-74.
    • (2006) Dev Dyn , vol.235 , pp. 2160-2174
    • Manisastry, S.M.1    Han, M.2    Linask, K.K.3
  • 38
    • 34347341779 scopus 로고    scopus 로고
    • Repression of Wnt/{beta}-catenin signaling in the anterior endoderm is essential for liver and pancreas development
    • McLin VA, Rankin SA, Zorn AM. Repression of Wnt/{beta}-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development 2007;134:2207-17.
    • (2007) Development , vol.134 , pp. 2207-2217
    • McLin, V.A.1    Rankin, S.A.2    Zorn, A.M.3
  • 40
    • 33747033130 scopus 로고    scopus 로고
    • Mesodermal Wnt2b signalling positively regulates liver specification
    • Ober EA, Verkade H, Field HA, Stainier DY. Mesodermal Wnt2b signalling positively regulates liver specification. Nature 2006;442:688-91.
    • (2006) Nature , vol.442 , pp. 688-691
    • Ober, E.A.1    Verkade, H.2    Field, H.A.3    Stainier, D.Y.4
  • 41
    • 0035066173 scopus 로고    scopus 로고
    • Nuclear localization of beta-catenin is an important prognostic factor in hepatoblastoma
    • Park WS, Oh RR, Park JY, Kim PJ, Shin MS, Lee JH, et al. Nuclear localization of beta-catenin is an important prognostic factor in hepatoblastoma. J Pathol 2001;193:483-90.
    • (2001) J Pathol , vol.193 , pp. 483-490
    • Park, W.S.1    Oh, R.R.2    Park, J.Y.3    Kim, P.J.4    Shin, M.S.5    Lee, J.H.6
  • 42
    • 0034308703 scopus 로고    scopus 로고
    • SIOPEL trials using preoperative chemotherapy in hepatoblastoma
    • Perilongo G, Shafford E, Plaschkes J. SIOPEL trials using preoperative chemotherapy in hepatoblastoma. Lancet Oncol 2000;1:94-100.
    • (2000) Lancet Oncol , vol.1 , pp. 94-100
    • Perilongo, G.1    Shafford, E.2    Plaschkes, J.3
  • 43
    • 9144254451 scopus 로고    scopus 로고
    • Riskadapted treatment for childhood hepatoblastoma. final report of the second study of the International Society of Paediatric Oncology-SIOPEL 2
    • Perilongo G, Shafford E, Maibach R, Aronson D, Brugieres L, Brock P, et al. Riskadapted treatment for childhood hepatoblastoma. final report of the second study of the International Society of Paediatric Oncology-SIOPEL 2. Eur J Cancer 2004;40:411-21.
    • (2004) Eur J Cancer , vol.40 , pp. 411-421
    • Perilongo, G.1    Shafford, E.2    Maibach, R.3    Aronson, D.4    Brugieres, L.5    Brock, P.6
  • 45
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev 2000;14:1837-51.
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 46
    • 27744548217 scopus 로고    scopus 로고
    • Beta-Catenin and met deregulation in childhood Hepatoblastomas
    • Ranganathan S, Tan X, Monga SP. beta-Catenin and met deregulation in childhood Hepatoblastomas. Pediatr Dev Pathol 2005;8:435-47.
    • (2005) Pediatr Dev Pathol , vol.8 , pp. 435-447
    • Ranganathan, S.1    Tan, X.2    Monga, S.P.3
  • 47
    • 57749087003 scopus 로고    scopus 로고
    • B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver
    • Reed KR, Athineos D, Meniel VS, Wilkins JA, Ridgway RA, Burke ZD, et al. B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver. Proc Natl Acad Sci USA 2008;105:18919-23.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 18919-18923
    • Reed, K.R.1    Athineos, D.2    Meniel, V.S.3    Wilkins, J.A.4    Ridgway, R.A.5    Burke, Z.D.6
  • 48
    • 33847073865 scopus 로고    scopus 로고
    • Tbx3 is a downstream target of the Wnt/β-catenin pathway and a criticalmediator of β-catenin survival functions in liver cancer
    • Renard CA, Labalette C, Armengol C, Cougot D,Wei Y, Cairo S, et al. Tbx3 is a downstream target of the Wnt/β-catenin pathway and a criticalmediator of β-catenin survival functions in liver cancer. Cancer Res 2007;67:901-10.
    • (2007) Cancer Res , vol.67 , pp. 901-910
    • Renard, C.A.1    Labalette, C.2    Armengol, C.3    Cougot Dwei, Y.4    Cairo, S.5
  • 49
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, Willert K, et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 2003;423: 409-14.
    • (2003) Nature , vol.423 , pp. 409-414
    • Reya, T.1    Duncan, A.W.2    Ailles, L.3    Domen, J.4    Scherer, D.C.5    Willert, K.6
  • 50
    • 0036836488 scopus 로고    scopus 로고
    • Hepatoblastoma: Assessment of criteria for histologic classification
    • Rowland JM. Hepatoblastoma: assessment of criteria for histologic classification. Med Pediatr Oncol 2002;39:478-83.
    • (2002) Med Pediatr Oncol , vol.39 , pp. 478-483
    • Rowland, J.M.1
  • 51
    • 0030823738 scopus 로고    scopus 로고
    • Hepatic stem-like cells in hepatoblastoma: Expression of cytokeratin 7, albumin and oval cell associated antigens detected by OV-1 and OV-6
    • Ruck P, Xiao JC, Pietsch T, Von Schweinitz D, Kaiserling E. Hepatic stem-like cells in hepatoblastoma: expression of cytokeratin 7, albumin and oval cell associated antigens detected by OV-1 and OV-6. Histopathology 1997;31:324-9.
    • (1997) Histopathology , vol.31 , pp. 324-9
    • Ruck, P.1    Xiao, J.C.2    Pietsch, T.3    Von Schweinitz, D.4    Kaiserling, E.5
  • 52
    • 0032125734 scopus 로고    scopus 로고
    • Cytogenetic analysis of hepatoblastoma: Hypothesis of cytogenetic evolution in such tumors and results of a multicentric study
    • Sainati L, Leszl A, Stella M, Montaldi A, Perilongo G, Rugge M, et al. Cytogenetic analysis of hepatoblastoma: hypothesis of cytogenetic evolution in such tumors and results of a multicentric study. Cancer Genet Cytogenet 1998;104:39-44.
    • (1998) Cancer Genet Cytogenet , vol.104 , pp. 39-44
    • Sainati, L.1    Leszl, A.2    Stella, M.3    Montaldi, A.4    Perilongo, G.5    Rugge, M.6
  • 53
    • 0035987667 scopus 로고    scopus 로고
    • Outcome of hepatoblastoma treated with the JPLT-1 (Japanese Study Group for Pediatric Liver Tumor) Protocol-1: A report from the Japanese Study Group for Pediatric Liver Tumor
    • Sasaki F, Matsunaga T, Iwafuchi M, Hayashi Y, Ohkawa H, Ohira M, et al. Outcome of hepatoblastoma treated with the JPLT-1 (Japanese Study Group for Pediatric Liver Tumor) Protocol-1: a report from the Japanese Study Group for Pediatric Liver Tumor. J Pediatr Surg 2002;37:851-6.
    • (2002) J Pediatr Surg , vol.37 , pp. 851-856
    • Sasaki, F.1    Matsunaga, T.2    Iwafuchi, M.3    Hayashi, Y.4    Ohkawa, H.5    Ohira, M.6
  • 54
    • 33749182067 scopus 로고    scopus 로고
    • The phenotypes of pluripotent human hepatic progenitors
    • Schmelzer E, Wauthier E, Reid LM. The phenotypes of pluripotent human hepatic progenitors. Stem Cells 2006;24:1852-8.
    • (2006) Stem Cells , vol.24 , pp. 1852-1858
    • Schmelzer, E.1    Wauthier, E.2    Reid, L.M.3
  • 57
    • 33645989449 scopus 로고    scopus 로고
    • Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice
    • Sekine S, Lan BY, Bedolli M, Feng S, Hebrok M. Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice. Hepatology 2006;43:817-25.
    • (2006) Hepatology , vol.43 , pp. 817-825
    • Sekine, S.1    Lan, B.Y.2    Bedolli, M.3    Feng, S.4    Hebrok, M.5
  • 58
    • 0034906471 scopus 로고    scopus 로고
    • Frequent deletions and mutations of the beta-catenin gene are associated with overexpression of cyclin D1 and fibronectin and poorly differentiated histology in childhood hepatoblastoma
    • Takayasu H, Horie H, Hiyama E, Matsunaga T, Hayashi Y, Watanabe Y, et al. Frequent deletions and mutations of the beta-catenin gene are associated with overexpression of cyclin D1 and fibronectin and poorly differentiated histology in childhood hepatoblastoma. Clin Cancer Res 2001;7:901-8.
    • (2001) Clin Cancer Res , vol.7 , pp. 901-908
    • Takayasu, H.1    Horie, H.2    Hiyama, E.3    Matsunaga, T.4    Hayashi, Y.5    Watanabe, Y.6
  • 59
    • 33750726092 scopus 로고    scopus 로고
    • Conditional deletion of beta-catenin reveals its role in liver growth and regeneration
    • Tan X, Behari J, Cieply B, Michalopoulos GK, Monga SP. Conditional deletion of beta-catenin reveals its role in liver growth and regeneration. Gastroenterology 2006;131:1561-72.
    • (2006) Gastroenterology , vol.131 , pp. 1561-1572
    • Tan, X.1    Behari, J.2    Cieply, B.3    Michalopoulos, G.K.4    Monga, S.P.5
  • 60
    • 43949133408 scopus 로고    scopus 로고
    • Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development
    • Tan X, Yuan Y, Zeng G, Apte U, Thompson MD, Cieply B, et al. Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development. Hepatology 2008;47:1667-79.
    • (2008) Hepatology , vol.47 , pp. 1667-1679
    • Tan, X.1    Yuan, Y.2    Zeng, G.3    Apte, U.4    Thompson, M.D.5    Cieply, B.6
  • 61
    • 0037130449 scopus 로고    scopus 로고
    • Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
    • Taniguchi K, Roberts LR, Aderca IN, Dong X, Qian C, Murphy LM, et al. Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 2002;21:4863-71.
    • (2002) Oncogene , vol.21 , pp. 4863-4871
    • Taniguchi, K.1    Roberts, L.R.2    Aderca, I.N.3    Dong, X.4    Qian, C.5    Murphy, L.M.6
  • 62
    • 0032528190 scopus 로고    scopus 로고
    • Increased risk of hepatoblastoma among immature children with a lower birth weight
    • Tanimura M, Matsui I, Abe J, Ikeda H, Kobayashi N, Ohira M, et al. Increased risk of hepatoblastoma among immature children with a lower birth weight. Cancer Res 1998;58:3032-5.
    • (1998) Cancer Res , vol.58 , pp. 3032-3035
    • Tanimura, M.1    Matsui, I.2    Abe, J.3    Ikeda, H.4    Kobayashi, N.5    Ohira, M.6
  • 63
    • 24944469682 scopus 로고    scopus 로고
    • Cytogenetic evaluation of a large series of hepatoblastomas: Numerical abnormalities with recurring aberrations involving 1q12-q21
    • Tomlinson GE, Douglass EC, Pollock BH, Finegold MJ, Schneider NR. Cytogenetic evaluation of a large series of hepatoblastomas: numerical abnormalities with recurring aberrations involving 1q12-q21. Genes Chromosomes Cancer 2005;44:177-84.
    • (2005) Genes Chromosomes Cancer , vol.44 , pp. 177-184
    • Tomlinson, G.E.1    Douglass, E.C.2    Pollock, B.H.3    Finegold, M.J.4    Schneider, N.R.5
  • 64
    • 0033900096 scopus 로고    scopus 로고
    • Characterization of genomic alterations in hepatoblastomas. A role for gains on chromosomes 8q and 20 as predictors of poor outcome
    • Weber RG, Pietsch T, von Schweinitz D, Lichter P. Characterization of genomic alterations in hepatoblastomas. A role for gains on chromosomes 8q and 20 as predictors of poor outcome. Am J Pathol 2000;157:571-8.
    • (2000) Am J Pathol , vol.157 , pp. 571-578
    • Weber, R.G.1    Pietsch, T.2    Von Schweinitz, D.3    Lichter, P.4
  • 66
    • 0008878205 scopus 로고
    • Primary hepatic tumors of childhood
    • Weinberg AG, Finegold MJ. Primary hepatic tumors of childhood. Hum Pathol 1983;14:512-37.
    • (1983) Hum Pathol , vol.14 , pp. 512-537
    • Weinberg, A.G.1    Finegold, M.J.2
  • 67
    • 41949105179 scopus 로고    scopus 로고
    • Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling
    • Wu X, Tu X, Joeng KS, Hilton MJ, Williams DA, Long F. Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell 2008;133:340-53.
    • (2008) Cell , vol.133 , pp. 340-353
    • Wu, X.1    Tu, X.2    Joeng, K.S.3    Hilton, M.J.4    Williams, D.A.5    Long, F.6
  • 68
    • 49249122615 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells
    • YangW, Yan HX, Chen L, Liu Q, He YQ, Yu LX, et al. Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells. Cancer Res 2008;68:4287-95.
    • (2008) Cancer Res , vol.68 , pp. 4287-4295
    • Yangw Yan, H.X.1    Chen, L.2    Liu, Q.3    He, Y.Q.4    Yu, L.X.5
  • 69
    • 22144477149 scopus 로고    scopus 로고
    • The emerging family of hepatoblastomatumours: Fromontogenesis to oncogenesis
    • ZimmermannA. The emerging family of hepatoblastomatumours: fromontogenesis to oncogenesis. Eur J Cancer 2005;41:1503-14.
    • (2005) Eur J Cancer , vol.41 , pp. 1503-1514
    • Zimmermann, A.1
  • 70
    • 33846846541 scopus 로고    scopus 로고
    • Differential effects of inactivated Axin1 and activated betacatenin mutations in human hepatocellular carcinomas
    • Zucman-Rossi J, Benhamouche S, Godard C, Boyault S, Grimber G, Balabaud C, et al. Differential effects of inactivated Axin1 and activated betacatenin mutations in human hepatocellular carcinomas. Oncogene 2007;26: 774-80.
    • (2007) Oncogene , vol.26 , pp. 774-80
    • Zucman-Rossi, J.1    Benhamouche, S.2    Godard, C.3    Boyault, S.4    Grimber, G.5    Balabaud, C.6


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